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a.socia.ion of Body Composition a.d a.robic Fitness on Hea.t Ra.e Va.ia.ility a.d Recovery in Young-a.ult Bla.k Men

Interna.iona. Journa. of Clinica. Medicine 2013年第12期4卷 532-538页

作者： Micha.l R. Esco Robert L. Herron Stephen J. Ca.ter andrew a. flatt Exercise Physiology La.ora.ory Department of Kinesiology The University of Alabama Tuscaloosa USA Huma. Performa.ce La.ora.ory Department of Physical Education and Exercise Science Auburn University at Montgomery Montgomery USA

Ba.kground: The prima.y purpose of this investiga.ion wa. to determine the differences in resting hea.t ra.e va.ia.ility a.d hea.t ra.e recovery between norm-referenced a.robic fitness groupings, independent of body composition, in Bla.k men. a.ditiona.ly, we sought to cla.ify the independent rela.ionships tha. hea.t ra.e va.ia.ility a.d hea.t ra.e recovery displa.ed with ma.ima. a.robic fitness a.d selected body composition mea.ures. Methods: Body ma.s index, wa.st circumference, a.d the sum of skinfold thickness were determined in forty Bla.k men (23 ± 3 yea.s). Ea.h subject a.sumed a.supine position while hea.t ra.e va.ia.ility wa. a.a.yzed for 5-minute a.d recorded a. norma.ized high-frequency power a.d norma.ized low-frequency power to norma.ized high frequency ra.io. a.gra.ed exercise trea.mill protocol wa. performed to a.ta.n ma.ima. a.robic fitness. Hea.t ra.e recovery wa. recorded a. 1- a.d 2-minute of a.cool-down period. Hea.t ra.e va.ia.ility a.d hea.t ra.e recovery were compa.ed a.ross two groups whose ma.ima. a.robic fitness wa. either below or a.ove the norma.ive mea. va.ue for the a.e group of men. Results: The results indica.ed tha. hea.t ra.e va.ia.ility wa. higher in the group whose ma.ima. a.robic fitness wa. a.ove the norma.ive mea. va.ue compa.ed with the lower fit group (p a.pea.ed when a.justing for body composition (p > 0.05). Regression a.a.ysis revea.ed tha. the sum of skinfolds a.counted for the va.ia.ion in norma.ized high frequency power (R2 = 0.20, p a.d norma.ized low-frequency power to norma.ized high frequency ra.io (R2 = 0.30, p a.st circumference a.counted for the va.ia.ion in hea.t ra.e recovery a. 2-minute (R2 = 0.20, p Conclusion: The results suggest tha. hea.t ra.e va.ia.ility a.d hea.t ra.e recovery hold independent rela.ionships to body composition but not a.robic fitness in young-a.ult, Bla.k men.

关键词： Skinfold Thickness Wa.st Circumference Ca.diova.cula. a.tonomic

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Soluble epoxide hydrola.e:a.next-genera.ion drug ta.get for a.zheimer's disea.e a.d rela.ed dementia.

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Neura. Regenera.ion Resea.ch 2025年第9期20卷 2585-2586页

作者： andrew Gregory Chengyun Ta.g Fa. Fa. Depa.tment of Physiology Medical College of GeorgiaAugusta UniversityAugustaGAUSA

a.zheimer's disea.e(a.)a.d a.zheimer's disea.erela.ed dementia.(a.RD)represent a.significa.t public hea.th cha.lenge,with projections indica.ing a.substa.tia. increa.e in a.fected individua.s due to the a.ing globa. *** the World Hea.th Orga.iza.ion,a./a.RD ha. a.fected more tha. 55 million individua.s worldwide,with a. a.ditiona. 10 million ca.es dia.nosed ea.h yea..

关键词： a.zheimer popula.ion drug

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Huma. endogenous retrovirus type-W a.d multiple sclerosis–rela.ed smoldering neuroinfla.ma.ion

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Neura. Regenera.ion Resea.ch 2025年第3期20卷 813-814页

作者： Joel Gruchot La.ra.Reiche andrew Cha. Robert Hoepner Pa.rick Küry Depa.tment of Neurology Medical Faculty and University Hospital DüsseldorfHeinrich Heine University DüsseldorfDüsseldorfGermany Depa.tment of Neurology InselspitalBern University Hospital and University of BernBernSwitzerland

Introduction to huma. endogenous retrovirus type-W(HERV-W): Genomic inherita.ce from the pa.t includes retrovira. sequences tha. ha.e been sta.ly incorpora.ed into our genomes a.d a.count for up to 8% of huma. DNa.

关键词： endogenous infla.ma.ion Huma.

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Experimenta. Study for Effect of Multi-Site Spa.k Ignition on Dedica.ed Hybrid Engine Performa.ce under High Dilution Condition

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Journa. of Therma. Science 2025年第1期34卷 254-267页

作者： Ya. Bowen Wa.ERS Benja.in Ha.NES andrew MCGHEE Mike HU Tiega.g DENG Wei PU Yongxia. Ma.Tia.yu Powertra.n Engineering R&D Center Chongqing Changan Automobile Co.Ltd. Cha.ga. UK R&D Centre Limited

In this study,a.triple spa.k ignition scheme wa. first designed on a.three-cylinder 1.5-L dedica.ed hybrid engine（DHE）.On this ba.is,the effect of different ignition modes on engine combustion a.d emission cha.a.teristics wa. studied,especia.ly under high dilution *** results tested a. 2000 r/min a.d 0.8 MPa.BMEP（bra.e mea. effective pressure） show tha. with highly increa.ed in-cylinder flow intensity,using only pa.sive precha.ber（PPC） ha. a.lower lea. limit tha. tha. with single centra. spa.k plug（CSP）,thereby lea.ing to slightly higher minimum fuel consumption a.d nitrogen oxides（NOx） *** side spa.k plugs（SSP）ba.ed on PPC ca. result in improved ca.a.ility of lea. limit extension a.d engine performa.ce tha. ***,the improvement level is lower tha. tha. with triple spa.k plugs（TSP）.a. the excess a.r ra.io λincrea.es,the a.va.ta.e of PPC a.d PPC with SSP in improving the combustion pha.ing compa.ed with CSP gra.ua.ly ***,the increa.ing tendency of their ignition dela. a.d combustion dura.ion is more *** a.ded SSP ba.ed on PPC ca. effectively shorten the ignition dela. of lea.er mixture,but the combustion dura.ion ca. be only slightly *** a.result,under extremely lea. condition,the a.va.ta.e of PPC a.d PPC with SSP in terms of combustion cha.a.teristics over CSP becomes much *** contra.t,the TSP ignition ca. a.hieve much shorter ignition dela. a.d combustion dura.ion simulta.eously under this *** to the highest a.a.la.le dilution level,the TSP ignition a.hieves the lowest ra. ***,it ca. a.so reduce the ra. ca.bon monoxide（CO） a.d hydroca.bons（HC） emissions compa.ed to CSP due to a.more thorough combustion of the end ga. *** on the excellent performa.ce of TSP,the highest engine bra.e therma. efficiency（BTE） wa. further *** results show tha. with norma. RON 92 fuel,the engine fina.ly a.hieved 43.69% a.d 45.02% BTE under stochiometric mode with exha.st

关键词： dedica.ed hybrid engine high dilution condition NOx emissions pa.sive precha.ber therma. efficiency triple spa.k plug scheme

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CO2-media.ed bica.bona.e conversion to concentra.ed forma.e in a.CEM-ba.ed electrolyzer

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Journa. of Energy Chemistry 2025年第1期100卷 605-611页

作者： Ha.cheng Xiong Donghua. Wu Ha.na. Li andrew Li Qikun Hu Siya. Song Bingjun Xu Qi Lu Sta.e Key La.ora.ory of Chemica. Engineering Department of Chemical Engineering Tsinghua University College of Chemistry a.d Molecula. Engineering Peking University Ordos La.ora.ory

Renewa.le energy-driven bica.bona.e conversion to va.ua.le chemica.s presents a. a.tra.tive stra.egy for mitiga.ing CO2emissions,a. bica.bona.e ca. be efficiently genera.ed from the ca.ture of a.mospheric CO2using a.ka.ine solutions with rea.tive *** this work,we present a.CO2-media.ed bica.bona.e conversion to pure forma.e using a.ca.ion excha.ge membra.e-ba.ed electrolyzer with a.25 cm2electrode *** electrolysis a.hieved selectivities exceeding 75%for forma.e a. a.tota. current of 2.5 a.a.hieving forma.e concentra.ions up to 1.2 M a.d yields a. high a. 95%over extended *** techno-economic a.sessment confirmed the economic via.ility of the process,highlighting the potentia. for bica.bona.e electrolysis a. a.susta.na.le method for producing va.ua.le chemica.s.

关键词： Electroca.a.ysis Techno-economic a.sessments Electrochemistry Flow electrolyzer

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Predicting Sta.da.dized Precipita.ion Eva.otra.spira.ion Index for Fa.a.N’Gourma.by 2050 Using CMPI-6 Outputs under SSPs Scena.ios

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Journa. of Environmenta. Science a.d Engineering(a. 2025年第1期14卷 31-42页

作者： Tog-Noma.Pa.ricia.Emma.Bontogho andrew Ireson Dominic Boa.eng-Gya.biby a.dulla.i Dini High Institute of Susta.na.le Development University Yembila Abdoulaye ToguyéniBP 54 Fada N’GourmaBurkina Faso Globa. Institute for Wa.er Security School of Environment and SustainabilityUniversity of SaskatchewanSaskatoonCanada Depa.tment of a.ricultura. a.d Resource Economics University of Energy and Natural Resourcescity P.O.Box 214SunyaniGhana

Extreme wea.her events,such a. floods a.d droughts,a.e expected to rise significa.tly worldwide a. a.result of clima.e *** future drought pa.terns is therefore a.key a.proa.h for ela.ora.ing a.ticipa.ory wa.er resources ma.a.ement responses to clima.e *** this pa.er,future meteorologica. drought conditions a.e investiga.ed ba.ed on the SPEI(Sta.da.dised Precipita.ion Eva.otra.spira.ion Index).This study ma.es use of observed a.d projected *** simula.ed da.a.were retrieved from the CMIP6(Coupled Model Intercompa.ison Project Pha.e 6)over the period 2025-2050,a.d the Delta.cha.ge method wa. a.opted to remove the bia. in the *** SPEI a. va.ious sca.es ha. been estima.ed under four future scena.ios(SSP1-2.6,SSP2-4.5,SSP3-7.0 a.d SSP5-8.5).The trend a.a.ysis of the projected SPEI wa. performed a. pa.n-Kenda.l)test in order to detect the sta.istica.ly significa.t trend of the drought a.a.nst the null hypothesis of no *** show la.ge va.ia.ility in the ma.nitude of drought in the pa.t a.d *** on SPEI a. 24 months a.cumula.ion,the result shows tha. under SSP1-2.6,the ba.in will experience a.wet period during the first deca.e(SPEI=0.60),the second deca.e will be dry(SPEI24=-0.43).The rema.ning yea.s will be a.so dry(SPEI=-0.34).Under SSP2-4.5,SSP3-7.0 a.d SSP5-8.5 scena.ios,the district will experience a.wet period during the first two deca.es with SPEI ra.ging from 0.38 to *** wet period will be followed by a.dry period under these scena.ios ra.ging from-0.14 ***,under SSPs scena.ios,two ma.n periods cha.a.terized by a.ra.nfa.l recovery spa.ning from followed by a.modera.ely prolonged drought a.e identified within the study *** findings of this study ma. provide va.ua.le informa.ion for developing proa.tive mea.ures to reduce wa.er insecurity in Fa.a.N’Gourma.through effective drought mitiga.ion.

关键词： Clima.e cha.ge drought index CMPI-6 Fa.a.N’Gourma SSP-scena.ios.

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Infla.ma.ome links tra.ma.ic bra.n injury, chronic tra.ma.ic encepha.opa.hy, a.d a.zheimer's disea.e

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Neura. Regenera.ion Resea.ch 2025年第6期20卷 1644-1664页

作者： Ga.riela.Seplovich Ya.a. Bouchi Jua. Pa.lo de Rivero Va.ca.i Jennifer C.Munoz Pa.eja.andrew Reisner La.ra.Bla.kwell Yehia.Mechref Kevin K.Wa.g J.a.ria. Tynda.l Binu Tha.a.a. Fira. Kobeissy Depa.tment of Surgery Morehouse School of MedicineAtlantaGAUSA Depa.tment of Neurobiology Center for NeurotraumaMultiomics&Biomarkers(CNMB)Neuroscience InstituteMorehouse School of MedicineAtlantaGAUSA Depa.tment of Neurologica. Surgery a.d the Mia.i Project to Cure Pa.a.ysis University of Miami Miller School of MedicineMiamiFLUSA Division of Pedia.ric Critica. Ca.e Department of PediatricsUniversity of Miami Miller School of MedicineMiamiFLUSA Depa.tment of Pedia.rics Emory UniversityAtlantaGAUSA Depa.tment of Neurosurgery Children’s Healthcare of AtlantaAtlantaGAUSA Depa.tment of Chemistry a.d Biochemistry Texas Tech UniversityLubbockTXUSA Morehouse School of Medicine AtlantaGAUSA

Tra.ma.ic bra.n injury, chronic tra.ma.ic encepha.opa.hy, a.d a.zheimer's disea.e a.e three distinct neurologica. disorders tha. sha.e common pa.hophysiologica. mecha.isms involving neuroinfla.ma.ion. One sequela.of neuroinfla.ma.ion includes the pa.hologic hyperphosphoryla.ion of ta. protein, a. endogenous microtubule-a.socia.ed protein tha. protects the integrity of neurona. cytoskeletons. Ta. hyperphosphoryla.ion results in protein misfolding a.d subsequent a.cumula.ion of ta. ta.gles forming neurotoxic a.grega.es. These misfolded proteins a.e cha.a.teristic of tra.ma.ic bra.n injury, chronic tra.ma.ic encepha.opa.hy, a.d a.zheimer's disea.e a.d ca. lea. to downstrea. neuroinfla.ma.ory processes, including a.sembly a.d a.tiva.ion of the infla.ma.ome complex. Infla.ma.omes refer to a.fa.ily of multimeric protein units tha., upon a.tiva.ion, relea.e a.ca.ca.e of signa.ing molecules resulting in ca.pa.e-induced cell dea.h a.d infla.ma.ion media.ed by the relea.e of interleukin-1β cytokine. One specific infla.ma.ome, the NOD-like receptor protein 3, ha. been proposed to be a.key regula.or of ta. phosphoryla.ion where it ha. been shown tha. prolonged NOD-like receptor protein 3 a.tiva.ion a.ts a. a.ca.sa. fa.tor in pa.hologica. ta. a.cumula.ion a.d sprea.ing. This review begins by describing the epidemiology a.d pa.hophysiology of tra.ma.ic bra.n injury, chronic tra.ma.ic encepha.opa.hy, a.d a.zheimer's disea.e. Next, we highlight neuroinfla.ma.ion a. a. overriding theme a.d discuss the role of the NOD-like receptor protein 3 infla.ma.ome in the forma.ion of ta. deposits a.d how such ta.opa.hic entities sprea. throughout the bra.n. We then propose a.novel fra.ework linking tra.ma.ic bra.n injury, chronic tra.ma.ic encepha.opa.hy, a.d a.zheimer's disea.e a. infla.ma.omedependent pa.hologies tha. exist a.ong a.tempora. continuum. Fina.ly, we discuss potentia. thera.eutic ta.gets tha. ma. intercept this pa.hwa. a.d ultima.ely minimize long-term neurologica. decline.

关键词： a.zheimer's disea.e ca.pa.e-1 chronic tra.ma.ic encepha.opa.hy infla.ma.omes neurodegenera.ion neuroinfla.ma.ion NLRP1 NLRP3 pyroptosis ta.opa.hy tra.ma.ic bra.n injury

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Do bla.k-furred a.ima.s compensa.e for high sola. a.sorption with sma.ler ha.rs？ a.test with a.polymorphic squirrel species

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Current Zoology 2011年第6期57卷 731-736页

作者： Mela.ie a. FRa.TO andrew K. Da.IS Odum School of Ecology The University of Georgia Athens GA USA 30602

In polymorphic ma.ma.ia. species tha. displa. multiple color forms, those with da.k, or mela.ic pela.e would be prone to overhea.ing, especia.ly if they live in wa.m clima.es, beca.se their fur a.sorbs sola. energy a. a.higher ra.e. However, experimenta. studies indica.e tha. certa.n physica. properties of fur of da.k individua.s a.pea. to prevent, or minimize hea. stress, a.though it is not clea. wha. properties do so. Here, we tested the possibility tha. bla.k-furred individua.s simply ha.e shorter or thinner ha.r fibers, which would crea.e a.lighter （in terms of weight） coa. or one tha. a.lows grea.er a.r flow for eva.ora.ive coo- ling. We exa.ined museum specimens of ea.tern fox squirrels Sciurus niger, a.species na.ive to the United Sta.es a.d one tha. displa.s brown, grey or a.l-bla.k pela.e color, a.d used ima.e a.a.ysis procedures to qua.tify ha.rs from the dorsa. surfa.e a.d ta.l. From exa.ina.ion of 43 specimens （19 brown, 9 bla.k a.d 15 grey）, a.d 1,720 ha.rs, we found no significa.t difference in ha.r lengths a.ross color morphs, but significa.t differences in ha.r fiber widths. Bla.k squirrels ha. thinner body ha.rs tha. other forms （7% thinner）, but thicker ta.l ha.rs （9% thicker） tha. the others. Given tha. the dorsa. surfa.e would be directly exposed to sola. ra.ia.ion, we interpret this to be a. a.a.ta.ion to prevent hea. stress during the da.. The thicker ta.l ha.rs ma. be a. a.a.ta. tion for nighttime thermoregula.ion, since squirrels sleep with their ta.ls wra.ped a.ound their bodies. These results a.d to a.growing litera.ure body of the functiona. significa.ce of ma.ma.ia. pela.e [Current Zoology 57 （6）： 731-736, 2011].

关键词： Polymorphism Mela.ism Fox squirrels Sciurus niger Hea. stress Ha.r morphology

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Selected physica. a.d chemica. properties of mecha.ica.ly extra.ted neem seed oil sourced a. a.preserva.ive for ligno-cellulose in south-western Nigeria

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Forestry Studies in China 2011年第4期13卷 263-269页

作者： andrew a. ERa.HRUMEN Depa.tment of Forest Resources Ma.a.ement Faculty of Agriculture and Forestry University of Ibadan Ibadan Nigeria

Most of the seeds produced by neem （a.a.ira.hta.indica.a. Juss） trees in Nigeria.a.e currently underutilized. Hence, releva.t litera.ure provides only limited informa.ion conceming ma.y of the seed oils from this country, especia.ly where it concems the potentia. a.plica.ions of these oils a. preserva.ives for ligno-cellulose a.a.nst bio-deteriora.ion. Using sta.da.d procedures therefore, this study wa. ca.ried out to eva.ua.e a.d document selected physica. a.d chemica. properties of neem seed oil （NSO）, mecha.ica.ly extra.ted using a.cold press a. 31.03 N-mm^-2 pressure a.d a.room tempera.ure of 25 ± 2℃. The results show tha. oil yield wa. 38.42% with a.specific gra.ity of 0.91 ± 0.01. The a.ount of a.id wa. 18.24 ± 1.31 mg KOH.g^-1 a.d tha. of iodine 93.12 ± 2.01 g-100 g^- 1, while sa.onifica.ion a.d peroxide va.ues were 172.88 ± 2.06 a.d 1.42 ± 0.04 mg·g^-1 respectively. The implica.ion of the va.ues obta.ned, pa.ticula.ly those for the chemica. properties, a. they concern the potentia. a.plica.ion of NSO a. a.preserva.ive for ligno-eellulose, is likely tha. it ma. be useful in this rega.d since the va.ues ma. support some of the documented a.ti-microbia. properties of the oil, a.though other physica. a.d chemica. properties tha. ma. a.fect this potentia. a.e recommended for investiga.ions. Conclusions a.d other recommenda.ions follow in line with the results of the study.

关键词： neem seed oil physica. a.d chemica. properties mecha.ica. extra.tion cold press

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Vibra.ion induced flow in hoppers:DEM 2D polygon model

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Pa.ticuology 2008年第6期6卷 455-466页

作者： Fera. Y. Fra.ge Pa.l a. La.gston andrew J. Ma.chett John Dodds Fa.ulty of Mining a.d Environmenta. Engineering Al-Hussein Bin Talal University Jordan Chemica. a.d Environmenta. Engineering Nottingham University University Park Chemica. Engineering University of Teesside Centre Ra.SODEE Ecole Des Mines

a.two-dimensiona. discrete element model （DEM） simula.ion of cohesive polygona. pa.ticles ha. been developed to a.sess the benefit of point source vibra.ion to induce flow in wedge-sha.ed hoppers. The pa.ticle-pa.ticle intera.tion model used is ba.ed on a.multi-conta.t principle. The first pa.t of the study investiga.ed pa.ticle discha.ge under gra.ity without vibra.ion to determine the critica. orifice size （Bc） to just susta.n flow a. a.function of pa.ticle sha.e. It is shown tha. polygona.-sha.ed pa.ticles need a.la.ger orifice tha. circula. pa.ticles. It is a.so shown tha. Bc decrea.es a. the number of pa.ticle vertices increa.es. a.dition of circula. pa.ticles promotes flow of polygons in a.linea. ma.ner. The second pa.t of the study showed tha. vibra.ion could enha.ce flow, effectively reducing Bc. The model demonstra.ed the importa.ce of vibra.or loca.ion （height）, consistent with previous continuum model results, a.d vibra.ion a.plitude in enha.cing flow.

关键词： Bulk solids Vibra.ion DEM Hoppers Ma.eria.s ha.dling Polygon

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