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Occupational physical activity, all-cause, cardiovascular disease, and cancer mortality in 349,248 adults: Prospective and longitudinal analyses of the MJ Cohort

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Journal of Sport and Health Science 2024年第4期13卷 579-589页

作者： Emmanuel Stamatakis Matthew N.Ahmadi Tiana-Lee Elphick Bo-Huei Huang Susan Paudel Armando Teixeira-Pinto Li-Jung Chen Borja del Pozo Cruz Yun-Ju Lai andreas Holtermann Po-Wen Ku Sydney School of Health Sciences Faculty of Medicine and HealthCharles Perkins CentreUniversity of SydneySydneyNSW 2006Australia Sydney School of Public Health Faculty of Medicine and HealthUniversity of SydneySydneyNSW 2006Australia Department of Exercise Health Science “National”Taiwan University of SportTaichung 40404China Department of Sports Science and Clinical Biomechanics University of Southern DenmarkOdense 5230Denmark Division of Endocrinology and Metabolism Department of Internal MedicinePuli Branch of Taichung Veterans General HospitalNantou 54552China National Research Centre for the Working Environment Copenhagen 2100Denmark Graduate Institute of Sports and Health Management “National”Chung Hsing UniversityTaichung 40227China

Background:Evidence on the health benefits of occupational physical activity(OPA)is *** examined the associations of baseline OPA and OPA changes with all-cause,cardiovascular disease(CVD),and cancer mortality and survival ***:This study included prospective and longitudinal data from the MJ Cohort,comprising adults over 18 years recruited in 1998-2016,349,248 adults(177,314 women)with baseline OPA,of whom 105,715(52,503 women)had 2 OPA measures at 6.3±4.2 years(mean±SD)*** were baseline OPA,OPA changes,and baseline leisure-time physical ***:Over a mean mortality follow-up of 16.2±5.5 years for men and 16.4±5.4 years for women,11,696 deaths(2033 of CVD and 4631 of cancer causes)in men and 8980 deaths(1475 of CVD and 3689 of cancer causes)in women *** moderately heavy/heavy baseline OPA was beneficially associated with all-cause mortality in men(multivariable-adjusted hazard ratio(HR)=0.93,95%confidence interval(95%CI):0.89-0.98 compared to light OPA)and women(HR=0.86,95%CI:0.79-0.93).Over a mean mortality follow-up of 12.5±4.6 years for men and 12.6±4.6 years for women,OPA decreases in men were detrimentally associated(HR=1.16,95%CI:1.01-1.33)with all-cause mortality,while OPA increases in women were beneficially(HR=0.83,95%CI:0.70-0.97)associated with the same *** or changes in OPA showed no associations with CVD or cancer ***:Higher baseline OPA was beneficially associated with all-cause mortality risk in both men and *** longitudinal OPA analyses partly confirmed the prospective findings,with some discordance between sex groups.

关键词： Cancer Cardiovascular disease Epidemiology Mortality

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Effects of combined aerobic,resistance and inspiratory training in patients with pulmonary hypertension:A systematic review

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World Journal of Critical Care Medicine 2024年第2期13卷 168-179页

作者： Christos Kourek Antonia Zachariou Eleftherios Karatzanos Michalis Antonopoulos Theodora Soulele andreas Karabinis Serafim Nanas Stavros Dimopoulos Department of Clinical Ergospirometry Exercise and Rehabilitation Laboratory1^(st)Department of Critical Care MedicineEvangelismos HospitalNational and Kapodistrian University of AthensAthens 10676Greece Department of Cardiology 417 Army Share Fund Hospital of AthensAthens 11521Greece Cardiac Surgery ICU Onassis Cardiac Surgery centerAthens 17674AtticaGreece Cardiac Surgery ICU Onassis Cardiac Surgery CenterAthens 17674Greece Cardiac Surgery Intensive Care Unit Onassis Cardiac Surgery CenterAthens 17674Greece Department of Clinical Ergospirometry Exercise and Rehabilitation LaboratoryNational and Kapodistrian University of AthensAthens 10676Greece

BACKGROUND Pulmonary hypertension(PH)is a serious progressive disorder of the modern world,characterized by endothelial dysfunction and impaired *** with PH usually present exercise intolerance from the very early stages and reduced exercise *** training has been shown to have beneficial effects in patients with cardiovascular ***,data regarding the effects of combined exercise training programs in patients with PH still remains *** To investigate the effects of combined exercise training programs on exercise capacity and quality of life in patients with *** Our search included all available randomized controlled trials(RCTs)regarding combined aerobic,resistance and inspiratory training programs in patients with PH in 4 databases(Pubmed,PEDro,Embase,CINAHL)from 2012 to *** RCTs were included in the final *** capacity,assessed by peak VO_(2)or 6-min walking test(6MWT),as well as quality of life,assessed by the SF-36 questionnaire,were set as the primary outcomes in our *** Peak VO_(2)was measured in 4 out of the 5 RCTs while 6MWT was measured in all *** indices of functional capacity were significantly increased in patients with PH who underwent combined exercise training compared to the controls in all of the included RCTs(P<0.05).Quality of life was measured in 4 out of 5 *** patients improved their quality of life in each group,however,only 2 RCTs demonstrated further improvement in patients performing combined training compared to *** By this systematic review,we have demonstrated that combined aerobic,resistance and inspiratory exercise training is safe and has beneficial effects on aerobic capacity and quality of life in patients with *** exercise training regimen may be part of the therapeutic strategy of the syndrome.

关键词： Pulmonary hypertension Exercise training Peak VO2 Functional capacity Quality of life

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基于GQFD的手持工具人机工程设计研究

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湖北工业大学学报 2024年第3期39卷 86-92页

作者：程文婷李慧 andreas Papenfuss 湖北工业大学工业设计学院湖北武汉430068 Atelier Papenfuss设计公司魏玛99423

为优化手持工具的用户使用体验,提出一种将基于灰色关联分析的质量功能展开(GQFD)与人机工程相结合的设计方法,并将其应用于手持工具的产品研发中。首先采用非参与式观察法观察用户行为并获取用户需求,并依据手持工具的人机工程设计原... 详细信息

为优化手持工具的用户使用体验,提出一种将基于灰色关联分析的质量功能展开(GQFD)与人机工程相结合的设计方法,并将其应用于手持工具的产品研发中。首先采用非参与式观察法观察用户行为并获取用户需求,并依据手持工具的人机工程设计原则将用户需求转化为对应的设计要素;再运用GQFD构建设计质量屋,对用户需求与设计要素的相关关系度进行量化评价,分析设计要素重要度,从而明确重点设计目标;最后根据人机工程学的原理和方法,对重点设计目标进行分析设计,得到最终的设计方案。将该方法应用于德国Prym公司的手工钳改良设计项目,设计结果不仅满足了用户使用需求,而且提升了用户体验,为手持工具类产品的创新设计提供一种新的研究思路。

关键词：手持工具质量功能展开人机工程灰色关联分析用户需求

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管道清洁机器人的创新应用

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现代制造 2024年第1期 27-29页

作者： andreas Seegen Ellen-Christine Rei 不详

地下排水管道需要定期的维护保养,而且最好是在不挖开地面的情况下进行维护保养。为此,Pipetronics公司开发了一种可对地下管道进行维护保养的机器人。这款机器人由Faulhaber公司研发生产的无刷直流电机来驱动机器人车轮运转,驱动机器... 详细信息

地下排水管道需要定期的维护保养,而且最好是在不挖开地面的情况下进行维护保养。为此,Pipetronics公司开发了一种可对地下管道进行维护保养的机器人。这款机器人由Faulhaber公司研发生产的无刷直流电机来驱动机器人车轮运转,驱动机器人的清洁工具完成地下管道的清洁。

关键词：机器人地下管道维护保养 Pipe 无刷直流电机创新应用清洁工具

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超越PISA:大变局时代背景下教育高质量发展的再定义

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全球教育展望 2024年第4期53卷 3-5页

作者：安德烈亚斯·施莱歇尔经济合作与发展组织(OECD)教育与技能司

二十年来,国际学生评估项目(PISA)所开展的全球测评不仅成为衡量各个国家和经济体教育发展质量的风向标,亦成为推动全球教育改革的催化剂。PISA 2022是经济合作与发展组织(OECD)在新冠疫情期间开展的新一轮国际测评,相对于成绩并未有明... 详细信息

二十年来,国际学生评估项目(PISA)所开展的全球测评不仅成为衡量各个国家和经济体教育发展质量的风向标,亦成为推动全球教育改革的催化剂。PISA 2022是经济合作与发展组织(OECD)在新冠疫情期间开展的新一轮国际测评,相对于成绩并未有明显波动的历轮测评,本轮测评结果显示,全球整体遭遇前所未有的成绩下滑。这意味着全球教育改革前功尽弃?抑或全球教育发展隐忧悄然而至?本刊在第一时间组织“PISA 2022深度解读”专栏,基于PISA 2022的数据结果对教育系统的韧性、学习效率和教师支持三个关键议题进行深入研究,并邀请OECD教育与技能司司长、教育政策特别顾问安德烈亚斯·施莱歇尔(andreas Schleicher)作为专栏评论人发表见解,从而对大变局时代背景下教育高质量发展做出再定义。期待本期专栏能对我国教育系统正在推进的教育高质量发展和建设教育强国的新使命、新任务有所启示。

关键词： PISA 深度解读教育强国学习效率成绩下滑测评结果施莱歇尔大变局

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精英足球运动员教育、训练与人才培养路径

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体育科研 2024年第3期45卷 11-19页

作者： andreas Hohmann Dirk Mack Maximilian Siener 张辉德国拜罗伊特大学拜罗伊特体育科学中心拜罗伊特95448 德国TSG霍芬海姆俱乐部(德甲)青年足球部辛斯海姆74889 浙江大学教育学院体育学系浙江杭州310058

儿童和青少年时期系统的足球训练,可以促进年轻足球运动员专项技能和专项体能的发展。旨在结合最新的研究成果、科学知识和应用实践,区分5岁到成年足球运动员的训练目标和方法,审视足球长期教育过程是否符合现代足球训练、运动表现和比... 详细信息

儿童和青少年时期系统的足球训练,可以促进年轻足球运动员专项技能和专项体能的发展。旨在结合最新的研究成果、科学知识和应用实践,区分5岁到成年足球运动员的训练目标和方法,审视足球长期教育过程是否符合现代足球训练、运动表现和比赛的要求。强调各个年龄组足球运动员应有特定的足球教育理念、训练目标和方法,这对青春期(U15和U17)及青春期后(U19和U21)的足球运动员尤其重要,因为他们必须准备并确保顺利过渡到精英足球运动员水平。

关键词：足球运动员教育与训练特定年龄组的训练目标与方法运动表现分析比赛形式

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向未来迈进科隆RTL广播中心非正式会议中心

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室内设计与装修 2024年第11期 98-103页

作者： [瑞士]Evolútion Design andreas Buchberger(摄影) 树林(编译) Evolution Design

在当今快速变化的工作环境中,企业越来越重视创造能够促进合作与创新的空间。RTL德国广播中心的新非正式会议中心正是这种理念的生动体现。建筑与设计工作室Evolution Design以其独特的设计和对细节的关注,打造了2个充满活力的会议中心... 详细信息

在当今快速变化的工作环境中,企业越来越重视创造能够促进合作与创新的空间。RTL德国广播中心的新非正式会议中心正是这种理念的生动体现。建筑与设计工作室Evolution Design以其独特的设计和对细节的关注,打造了2个充满活力的会议中心,为员工提供了一个既舒适又功能齐全的社交与工作空间。

关键词：广播中心非正式会议设计工作室 RTL 合作与创新

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Chemical Bonding and Interpretation of Time-Dependent Electronic Processes with Maximum Probability Domains

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物理化学学报 2018年第5期34卷 528-536页

作者： SAVIN andreas Laboratoire de Chimie Theorique CNRS and Sorbonne Universite UPMC Univ Paris 06 4 place Jussieu F 75252 Paris cedex 05France.

Tools have been designed obtain information about chemical bonds from quantum mechanical *** work well for solutions of the stationary Schr?dinger equation, but it is not clear whether Lewis electron pairs they aim to reproduce survive in time-dependent processes, in spite of the underlying Pauli principle being obeyed in this regime. A simple model of two same-spin non-interacting fermions in a one-dimensional box with an opaque wall, is used to study this problem, because it allows presenting the detailed structure of the wave function. It is shown that i)oscillations persisting after the Hamiltonian stopped changing produce for certain time intervals states where Lewis electron pairs are spatially separated, and ii) methods(like density analysis, or the electron localization function) that are widely used for describing bonding in the stationary case, have limitations in such situations. An exception is provided by the maximum probability domain(the spatial domain that maximizes the probability to find a given number of particles in it). It is conceptually simple, and satisfactorily describes the phenomenon.

关键词：量子力学化学键化学分析波函数

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Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada Patrick Heimel Markus Kerbl LászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi andreas H.Teuschl-Woller David Hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). However, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

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Better understanding of c-reactive protein and leukocytes in psychiatric inpatients with affective disorders:A biopsychosocial approach

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World Journal of Clinical Cases 2024年第19期12卷 3824-3836页

作者： Felix Kölblinger Elena MD Schönthaler andreas Baranyi Tatjana Stross Frederike T Fellendorf Dirk von Lewinski Robert Queissner Eva Z Reininghaus Nina Dalkner Clinical Department of Psychiatry and Psychotherapeutic Medicine Medical University of GrazGraz 8036Austria Clinical Department of Cardiology Medical University of GrazGraz 8036Austria

BACKGROUND Affective disorders(AD)have been linked to inflammatory processes,although the underlying mechanisms of this relationship are still not fully *** is hypothesized that demographic,somatic,lifestyle,and personality variables predict inflammatory parameters in *** To identify biopsychosocial factors contributing to inflammation in AD measured with two parameters,C-reactive protein(CRP)and *** This observational study investigated 186 hospital inpatients diagnosed with AD using demographic parameters,serum inflammatory markers,somatic variables,psychological questionnaires,and lifestyle *** regression analyses were used to predict inflammatory markers from demographic,somatic,lifestyle,and personality *** Analyses showed that 33.8%of the variance of CRP was explained by body mass index and other somatic medication(***-diabetics),age and education,and age of affective disorder *** leukocytes,20.1%of the variance was explained by smoking,diet,metabolic syndrome(MetS),and anti-inflammatory medication(***-steroidal anti-inflammatory drugs).Other psychiatric or behavioural variables did not reach *** Metabolic components seem important,with mounting evidence for a metabolic affective disorder *** modifications and psychoeducation should be employed to prevent or treat MetS in AD.

关键词： Affective disorders C-reactive protein Leukocytes Metabolic syndrome Health behaviour Personality

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