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World Journal of Diabetes 2017年第4期8卷 120-129页

作者： Aik.terini Trik.alinou Athanasia k.Papazafiropoulou andreas Melidonis Department of Internal Medicine and Diabetes Center Tzaneio General Hospital of Piraeus18536 PiraeusGreece

It is true that a primary goal of diabetes early diagnosis and treatment is quality of life(QoL). The term QoL is still confusing but it is agreed that it composes of four components:The physical component, mental, cogitative component, psychological and social component. Many articles have been written addressing those four components. During the last five years 15500 articles and reviews have been written addressing diabetes and coronary arterial disease, 16100 addressing diabetes and renal function, 28900 addressing diabetes and retinopathy, 16800 addressing diabetic foot ulcers and other 26300 addressing diabetic neuropathy. Moreover 17200 articles are dealing with diabetic sexual dysfunction, 24500 with the correlation of diabetes and depression 17500 about diabetes and dementia, only 1 about diabetes and family functioning and 1950000 about diabetes and QoL, indicating the worldwide interest. In order to confront this metabolic anomaly and its consequences, researchers developed numerous generic and disease specific psychometric tools. With the aid of those psychometric tools the scientific community has started to realize the gruesome effect of diabetes on patients' lives. Diabetic's QoL becomes worse when complications start to develop or comorbidities coexist. Dominant amongst complications, in health-related quality of life(HRQoL) lowering, but not related to risk.factors(genetic, the weight of birth, or others) is coronary arterial disease followed by renal failure, blindness, and the combination of micro-and macrovascular complications and in some studies by sexual dysfunction. Moreover many are the comorbidities which deteriorate further the effect of diabetes in a patient life. Among them obesity, hypertension, dyslipidemia, depression, arthritis are the most common. Most intriguing field for research is the interaction of diabetes and depression and in some cases the progression to dementia. Many aspects and combinations of actions are under researche

关键词： Type 2 diabetes Quality of life Diabetes co morbidities Diabetes complications Dementia Diabetes type 3

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Tunable structural colors on display

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Light(Science & Applications) 2022年第6期11卷 1036-1037页

作者： andreas Tittl Chair in Hybrid Nanosystems Nanoinstitute MunichFaculty of PhysicsLudwig-Maximilians-Universitat MünchenKoniginstraβe 1080539 MünchenGermany

Structural coloration tak.s inspiration from the bright hues found in nature to control the reflection and transmission of light from artificially structured *** them with active electrical tuning heralds break.hrough... 详细信息

关键词： materials tuning break.hrough

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Geoscience material structures prediction via CALYPSO methodology

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Chinese Physics B 2019年第10期28卷 38-49页

作者： andreas Hermann Centre for Science at Extreme Conditions and SUPA School of Physics and Astronomy The University of Edinburgh

Many properties of planets such as their interior structure and thermal evolution depend on the high-pressure properties of their constituent materials. This paper reviews how crystal structure prediction methodology can help shed light on the transformations materials undergo at the extreme conditions inside planets. The discussion focuses on three areas:(i) the propensity of iron to form compounds with volatile elements at planetary core conditions(important to understand the chemical mak.up of Earth's inner core),(ii) the chemistry of mixtures of planetary ices(relevant for the mantle regions of giant icy planets), and(iii) examples of mantle minerals. In all cases the abilities and current limitations of crystal structure prediction are discussed across a range of example studies.

关键词： crystal structure prediction core materials planetary ices hydrous minerals

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On the Separation Mechanism between a Shark.s Tooth and Its Jaw Base, with Special Emphasis on an Observation Made from a White Shark. <i>Carcharodon carcharias</i>

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Open Journal of Animal Sciences 2018年第3期8卷 329-334页

作者： Erich k. Ritter andreas Dellios Department of Mathematics & Statistics University of West Florida Pensacola FL USA Shark.Research Institute Global Shark.Attack.File Princeton NJ USA Shark.School 5970 Osprey Place Pensacola FL USA

Feeding is the lik.ly cause for tooth shedding in shark.. Although the overall process of loosing teeth has been well studied, hardly any emphasis has been given to the actual separation mechanism between a shark.s tooth base and the surrounding jaw tissue. Attention is given to this very process, in connection to a never before videotaped tooth loss of a white shark. Carcharodon carcharias, that occurred within 0.3 seconds. Since the shark.did not bite into anything prior to this observation, the cause for this tooth loss does not seem feeding but fatigue related, triggered through a combination of mechanical and potentially biochemical degradation processes.

关键词： Shark Tooth Loss Tooth Shedding White Shark

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Plasma optics improving plasma accelerators

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Light(Science & Applications) 2022年第9期11卷 1954-1955页

作者： andreas Dopp Ludwig-Maximilians-Universit?t Munchen GarchingGermany

Plasma accelerators driven by high-power lasers can provide high-energy electron beams on a dramatically smaller scale than conventional radio-frequency ***,the performance of these accelerators is fundamentally limited by the diffraction of the ***-generated plasma waveguides can mitigate this problem and,combined with a controlled injection method for electrons,highlight the potential of novel laser-plasma optics.

关键词： optics Plasma conventional

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Numerical micro-texture optimization for lubricated contacts-A critical discussion

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Friction 2022年第11期10卷 1772-1809页

作者： Max MARIAN andreas ALMQVIST andreas ROSENk.ANZ Michel FILLON Department of Mechanical and Metallurgical Engineering Pontificia Universidad Católica de ChileSantiago 690411Chile Division of Machine Elements LuleåUniversity of TechnologyLuleåSE-97187Sweden Department of Chemical Engineering Biotechnology and MaterialsFCFMUniversity of ChileSantiago 8370456Chile Institut Pprime CNRSUniversity of PoitiersPoitiers Cedex TSA 4112386073France

Despite numerous experimental and theoretical studies reported in the literature,surface micro-texturing to control friction and wear in lubricated tribo-contacts is still in the trial-and-error *** tribological behaviour and advantageous micro-texture geometries and arrangements largely depend on the contact type and the operating *** scale implementation is hampered by the complexity of numerical *** substantiates the urgent need to numerically design and optimize micro-textures for specific *** these aspects have not been covered by other review articles yet,we aim at summarizing the existing state-of–the art regarding optimization strategies for micro-textures applied in hydrodynamically and elastohydrodynamically lubricated *** analysis demonstrates the great potential of optimization strategies to further tailor micro-textures with the overall aim to reduce friction and wear,thus contributing toward an improved energy efficiency and sustainability.

关键词： micro-texturing hydrodynamics elastohydrodynamics tribo-simulation optimization

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SMRs-overview,international developments,safety features and the GRS simulation chain

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Frontiers in Energy 2021年第4期15卷 793-809页

作者： andreas SCHAFFRATH andreas WIELENBERG Robert k.LGER Armin SEUBERT Gesellschaft für Anlagen-und Reak.orsicherheit gGmbH Boltzmannstrasse 1485748 Garching near MunichGermany

The Gesellschaft für Anlagen-und Reak.orsicherheit(GRS)gGmbH as the main technical support organization for the German Federal Government in nuclear safety has been dealing with small modular reactors(SMRs)for about one decade since SMRs are one interesting option for new builds in most countries worldwide which continue to use nuclear energy for commercial electricity *** four different SMR designs are in operation,four in construction,one is licensed,and further 12 are in a licensing *** this paper,definitions,history,and current developments of SMRs are ***,selected trends of SMR development such as factory fabrication and transport,compactness and modularity,core design,improved core cooling,exclusion of accidents,features for preventing and limiting the impact of severe accidents,economic viability,competitiveness and licensing are *** gaps of the GRS simulation chain programs with a view to applications in nuclear licensing procedures are identified and a strategy for closing these gaps is ***,selected work.on the extension and improvement of the simulation chain and first generic test analyses are presented.

关键词： small modular reactors(SMRs) history recent developments safety aspects simulation chain of the Gesellschaft für Anlagen-und Reak.orsicherheit(GRS)

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Targeted nanopore sequencing for the identification of novel PRMT1 circRNAs unveils a diverse transcriptional profile of this gene in breast cancer cells

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Genes & Diseases 2024年第2期11卷 589-592页

作者： Maria Papatsirou andreas Scorilas Diamantis C.Sideris Christos k.k.ntos Department of Biochemistry and Molecular Biology National and Kapodistrian University of AthensPanepistimiopolisAthens GR 15701Greece

Long-read sequencing with nanopore technology has been widely utilized for the identification of the full-length sequence of RNA molecules."It is especially suitable for the identification of circular RNAs(circRNAs),which are regulatory molecules that are regarded as promising non-invasive biomark.rs for various human malignancies,including breast cancer.2 The impact of circRNAs derived from the protein arginine methyltransferase 1(PRMT1)gene has not been clarified yet,even though the effect of PRMT1-mediated methylation on breast cancer cell characteristics has been well established.

关键词： PRMT1 breast cancer

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The significance of cherts as mark.rs of Ocean Plate Stratigraphy and paleoenvironmental conditions:New insights from the Neoproterozoic-Cambrian Blovice accretionary wedge,Bohemian Massif

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Geoscience Frontiers 2023年第1期14卷 162-180页

作者： Luk.šAck.rman Jirízák.Václav k.chlík.Jan Pašava k.relZák.andreas Pack.František.Veselovsk. Ladislav Strnad Institute of Geology of the Czech Academy of Sciences Rozvojová269CZ-16500 Prague 6Czech Republic Czech Geological Survey Klárov3CZ-11821 Prague 1Czech Republic Institute of Geology and Paleontology Faculty of ScienceCharles UniversityAlbertov 6Prague 12843Czech Republic Geowissenschaftliches Zentrum Universität GöttingenGoldschmidtstraβe 1D-37077 GöttingenGermany Laboratories of the Geological Institutes Faculty of ScienceCharles UniversityAlbertov 6Prague 12843Czech Republic

The Ediacaran to early Cambrian Blovice accretionary complex,Bohemian Massif,hosts abundant chert bodies that formed on an oceanic plate and were involved in subduction beneath the northern margin of *** relationships of cherts to their host,their microstructure and elemental as well as isotopic compositions revealed diverse processes of chert petrogenesis reflecting depositional environment and position on the oceanic *** deep-water cherts formed through a hydrothermal precipitation of silica-rich gels on outer trench swell of the subducted slab with none or only minor addition of terrigenous *** the contrary,the shallow-water cherts formed in lagoons on seamount slopes,and at least some of them represent a product of hydrothermal replacement of former carbonate and/or evaporite *** both chert types,the hydrothermal fluids were of low temperature and continuous pervasive hydrothermal alteration of oceanic crust,together with an elevated Si content in Neoproterozoic seawater,served as the major source of *** the other hand,minor carbon enrichment in chert is mostly link.d to variable incorporation of organic matter that was deposited on the *** earth element(REE)systematics of the cherts indicate predominantly oxygenated environment for the shallow-water cherts whereas the deep-water cherts were deposited in diverse redox conditions,depending on their distance from hydrothermal *** these data,we demonstrate that the cherts once formed a part of Ocean Plate Stratigraphy(OPS)now dismembered and mixed with terrigenous siliciclastic material to form OPS mé*** our data with those from the existing literature,we show that cherts can serve as significant mark.rs of OPS since the Archean,recording a complex interplay between seafloor-related volcanic(production of MORB-and OIB-lik. magmas)and sedimentary processes,hydrothermal activity at mid-ocean ridges and seamount chains as well as at outer slopes o

关键词： Chert Accretionary wedge Ediacaran Triple oxygen isotopes Strontium isotopes Ocean Plate Stratigraphy

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Dependence of impact regime boundaries on the initial temperatures of projectiles and targets

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Defence Technology（防务技术） 2024年第1期31卷 49-57页

作者： Stefano Signetti andreas Heine Fraunhofer-Institut für k.rzzeitdynamik Ernst-Mach-InstitutEMIErnst-Zermelo-Str.479104 Freiburg im BreisgauGermany

Towards higher impact velocities,ballistic events are increasingly determined by the material *** effects might range from moderate thermal softening to full phase *** particular,it is of great interest to quantify the conditions for incipient or full melting of metals during impact interactions,which result in a transition from still strength-affected to hydrodynamic material *** this work.we investigate to which extent the respective melting thresholds are also dependent on the initial,and generally elevated,temperatures of projectiles and targets before *** is studied through the application of a model developed recently by the authors to characterize the transition regime between high-velocity and hypervelocity impact,for which the melting thresholds of materials were used as the defining *** obtained results are expected to be of general interest for ballistic application cases where projectiles or targets are *** conditions might result,for example,from aerodynamic forces acting onto a projectile during atmospheric flight,explosive shapedcharge-jet formation or armor exposure to environmental *** performed analyses also broaden the scientific understanding of the relevance of temperature in penetration events,generally k.own since the 1960s,but often not considered thoroughly in impact studies.

关键词： Ballistic impact Thermal effects Metallic targets Energy partitioning Homologous temperature

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