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World Journal of Orthopedics 2023年第11期14卷 836-842页

作者： Grayson Kelmer andrea h johnson Justin J Turcotte Daniel E Redziniak Orthopedic Research Anne Arundel Medical CenterAnnapolisMD 21401United States Medical School Campbell University School of Osteopathic MedicineLillingtonNC 27546United States Orthopedic Surgery Anne Arundel Medical CenterAnnapolisMD 21401United States

BACKGROUND Cyclops lesions are a known complication of anterior cruciate ligament(ACL)reconstruction,with symptomatic cyclops syndrome occurring in up to 11%of *** cyclops lesions have been rarely documented;this case study documents the successful treatment of a recurrent cyclops *** SUMMARY A 28-year-old female presented following a non-contact injury to the right *** and clinical exam revealed an ACL tear,and arthroscopic reconstruction was *** years later a cyclops lesion was discovered and removed via arthroscopic *** months postoperatively,the patient presented with pain,stiffness,and difficulty achieving terminal extension.A smaller recurrent cyclops lesion was diagnosed,and a repeat synovectomy was *** patient recovered *** To the best of our knowledge,this is the first documented case of recurrent cyclops lesion after bone-patellar tendon-bone allograft ACL reconstruction presenting as cyclops syndrome.

关键词： Anterior cruciate ligament Cyclops lesion Cyclops syndrome Knee arthroscopy Anterior cruciate ligament reconstruction Case report

The outcomes and safety of patients undergoing endoscopic retrograde cholangiopancreatography combining a single-use cholangioscope and a single-use duodenoscope:A multicenter retrospective international study

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hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 71-76页

作者： Alessandro Fugazza Matteo Colombo Michel Kahaleh V.Raman Muthusamy Bick Benjamin Wim Laleman Carmelo Barbera Carlo Fabbri Jose Nieto Abed Al-Lehibi Mohan Ramchandani Amy Tyberg haroon Shahid Avik Sarkar Dean Ehrlich Stuart Shermand Cecilia Binda Marco Spadaccini andrea Iannone Kareem Khalaf Nageshwar Reddy andrea Anderloni Alessandro Repici Division of Gastroenterology and Digestive Endoscopy Humanitas Research Hospital-IRCCSVia Manzoni 5620089RozzanoMilanoItaly Gastroenterology Rutgers Robert Wood JohnsonNew BrunswickNew JerseyUSA Vatche and Tamar Manoukian Division of Digestive Diseases University of CaliforniaLos Angeles School of Medicine at UCLALos AngelesCaliforniaUSA Division of Digestive and Liver Disorders Indiana University School of MedicineIndianapolisINUSA Department of Gastroenterology and hepatology University Hospitals LeuvenKU Leuven3000 LeuvenBelgium U.O.C.di Gastroenterologia ed Endoscopia Digestiva Ospedale Giuseppe MazziniASL TeramoItaly Gastroenterology and Digestive Endoscopy Unit Forlì-Cesena HospitalsAUSL RomagnaForlì-CesenaItaly Borland Groover Clinic JacksonvilleFloridaUSA Department of Gastroenterology and hepatology King Fahad Medical CityRiyadhSaudi Arabia Asian Institute of Gastroenterology HyderabadIndia Section of Gastroenterology Department of Emergency and Organ TransplantationUniversity of BariBari 70124Italy Department of Biomedical Sciences Humanitas UniversityVia Rita Levi Montalcini 420090Pieve EmanueleMilanItaly

Background: Duodenoscope-related multidrug-resistant organism(MDRO) infections raise concerns. Disposable duodenoscopes have been recently introduced in the market and approved by regulatory agencies with the aim to reduce the risk of endoscopic retrograde cholangiopancreatography(ERCP) associated infections. The aim of this study was to evaluate the outcome of procedures performed with single-use duodenoscopes in patients with clinical indications to single-operator cholangiopancreatoscopy. Methods: This is a multicenter international, retrospective study combining all patients who underwent complex biliopancreatic interventions using the combination of a single-use duodenoscope and a single-use cholangioscope. The primary outcome was technical success defined as ERCP completion for the intended clinical indication. Secondary outcomes were procedural duration, rate of cross-over to reusable duodenoscope, operator-reported satisfaction score(1 to 10) on performance rating of the single-use duodenoscope, and adverse event(AE) rate. Results: A total of 66 patients(26, 39.4% female) were included in the study. ERCP was categorized according to ASGE ERCP grading system as 47(71.2%) grade 3 and 19(28.8%) grade 4. The technical success rate was 98.5%(65/66). Procedural duration was 64(interquartile range 15-189) min, cross-over rate to reusable duodenoscope was 1/66(1.5%). The satisfaction score of the single-use duodenoscope classified by the operators was 8.6 ± 1.3 points. Four patients(6.1%) experienced AEs not directly related to the single-use duodenoscope, namely 2 post-ERCP pancreatitis(PEP), 1 cholangitis and 1 ***: Single-use duodenoscope is effective, reliable and safe even in technically challenging procedures with a non-inferiority to reusable duodenoscope, making these devices a viable alternative to standard reusable equipment.

关键词： Single-operator cholangioscopy Single-use duodenoscope Endoscopic retrograde cholangiopancreatography Indeterminate biliary stricture Difficult biliary stones

Marked elevation of B-type natriuretic peptide in patients with heart failure and preserved ejection fraction

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The Journal of Biomedical Research 2014年第4期28卷 255-261页

作者： Samuel Tate andrea Griem Blythe Durbin-johnson Clifton Watt Saul Schaefer Department of Internal Medicine Division of Cardiovascular MedicineUniversity of California DavisDavisCAUSA Department of Public health Sciences Division of BiostatisticsUniversity of California DavisDavisCAUSA Cardiology Section Department of Veteran AffairsNorthern California Health Care SystemMatherCAUSA

Marked elevations of B-type natriuretic peptide （BNP） are not generally seen in patients with heart failure and preserved ejection fraction （hFpEF）. The objective of this study was to examine the clinical and laboratory characteristics of a large cohort of patients with hFpEF and markedly elevated BNP. A retrospective examination of 421 inpatients at a university hospital admitted with a diagnosis of hFpEF was performed. Clinical and echocardiographic data in 4 groups of patients with levels of BNP ≤ 100 pg/mL, 100-400 pg/mL, 400-1,000 pg/mL and 〉 1,000 pg/mL were compared. Patients with hFpEF and BNP 〉 1,000 pg/mL （28% of the population） were characterized by impaired renal function and greater use of anti-hypertensive medications. A subset of these patients with BNP 〉 1,000 pg/mL had normal renal function （21%） and were significantly older, more frequently female, and tended to have lower ejection fractions. Conversely, patients with hFpEF and BNP ≤100 pg/mL were younger and had preserved renal function. BNP was inversely related to the likelihood of subsequent admission for heart failure, but not to myocardial infarction or death. In conclusion： BNP 〉 1,000 pg/mL is seen in almost 1/3 of patients hospitalized with hFpEF. This elevation of BNP often reflects impaired renal function, but can also be seen in patients with preserved renal function but relatively impaired systolic function.

关键词： B-type natriuretic peptide diastolic heart failure chronic kidney disease

Appendectomy for Appendicitis has Worse hospital Outcomes in Inflammatory Bowel Disease Patients

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Journal of Biosciences and Medicines 2018年第5期6卷 23-35页

作者： Ravi Babu Pavurala andrea johnson Alice hinton Somashekar G. Krishna Anita Afzali Cheng Zhang Department of Medicine College of Medicine The Ohio State University Columbus OH USA Division of Gastroenterology Hepatology &amp amp Nutrition College of Medicine The Ohio State University Columbus OH USA Division of Biostatistics College of Public Health The Ohio State University Columbus OH USA Department of Gastroenterology MercyCrest Gastroenterology Springfield OH USA

Background and Aims: Appendectomy is the choice of surgery for appendicitis but little is known about its outcomes in patients with Inflammatory Bowel Disease (IBD). We sought to compare hospital outcomes of appendectomy for appendicitis between patients with and without IBD. Methods: This is a cross-sectional study utilizing the Nationwide Inpatient Sample between 2009 and 2013. Patients with appendicitis undergoing appendectomy were identified using appropriate International Classification of Diseases codes. Primary outcomes of interest included length of stay (LOS), hospital costs, and post-surgical complications. Univariate and multivariate analyses were used to compare these outcomes between patients with and without IBD. Results: A total of 849,312 patients with appendicitis undergoing appendectomy were included in this study, of which 4261 patients had IBD. IBD patients had longer LOS and increased hospital costs. Crohn’s disease (CD) patients were more likely to develop post-operative pulmonary embolism (adjusted odds ratio (aOR) 7.06, 95% Confidence Interval (CI) (2.19, 22.79)) and anemia (aOR 2.23, 95% CI (1.21, 4.10)), whereas ulcerative colitis patients were more likely to develop post-operative deep vein thrombosis (aOR 9.79, 95% CI (2.41, 39.75)). CD patients were more likely to have perforated ap-pendicitis (aOR 1.37, 95% CI (1.67, 1.11)) and open appendectomy (aOR 1.56, 95% CI (1.96, 1.27)). Conclusions: Appendectomy for appendicitis in IBD patients is associated with adverse hospital outcomes. Focused attempts are needed to decrease the risk of DVT and PE in these patients. Treating patient’s pre-surgical anemia and proactive venous thromboembolism prophylaxis in IBD patients undergoing appendectomy for appendicitis might improve hos-pital outcomes.

关键词： Ulcerative Colitis Crohn’s Disease Inflammatory Bowel Disease Appendicitis Appendectomy Outcomes

The Deep Carbon Observatory: A Ten-Year Quest to Study Carbon in Earth

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Engineering 2019年第3期5卷 372-378页

作者： Craig M. Schiffries andrea johnson Mangum Jennifer L. Mays Michelle hoon-Starr Robert M. hazen Geophysical Laboratory Carnegie Institution for Science Washington DC 20015 USA

1. Overview The Deep Carbon Observatory (DCO) is a ten-year research program to investigate the quantities, movements, forms, and origins of carbon in Earth. More than 90% of Earth’s carbon may reside in the planet’s deep interior, and DCO’s overarching mission is to understand Earth’s entire carbon cycle—beyond the atmosphere, oceans, and shallow crustal environments, which have drawn most previous research attention—to include the deep carbon cycle [1,2]. A decade of focused research has led to major discoveries by DCO scientists on the physical, chemical, and biological roles of carbon in Earth.

关键词： Deep Carbon Earth

Massive gastrointestinal bleeding: An unusual case of asymptomatic extrarenal, visceral, fibromuscular dysplasia

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World Journal of Gastroenterology 2007年第43期13卷 5771-5774页

作者： Paula andrea Rodriguez Urrego Mark Flanagan Wilson S Tsai Craig Rezac Nicola Barnard Department of Pathology Robert Wood Johnson Medical School-University of Medicine and Dentistry of New Jersey United States Department of Surgery RWJMS-UMDNJ United States Department of heart Lung and Esophageal Surgery University of Pittsburgh Medical Center United States

Extrarenal fibromuscular dysplasia causing gastro- intestinal bleeding without other manifestations and especially sparing renal vasculature is uncommon. The diagnosis of this entity is usually made by radiographic appearance and the treatment is controversial. To our knowledge only seven cases of visceral fibromuscular dysplasia as a primary manifestation of the disease have been described, symptoms range from abdominal pain to gangrene. This is the first case of visceral fibromuscular dysplasia presenting with otherwise asymptomatic gastrointestinal bleeding, without bowel necrosis or ischemic changes. We provide a review of the literature.

关键词： Fibromuscular dysplasia Extrarenal Visceral Gastrointestinal bleeding Intimal fibroplasia

Rare presentation of post-transplant lymphoproliferative disorder isolated to gastroesophageal junction

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World Journal of Gastrointestinal Oncology 2013年第12期5卷 230-234页

作者： Brad M haverkos Veeral M Oza andrea johnson Jon Walker Arwa Shana'ah Department of Medicine Division of He-matology and Medical Oncology Ohio State University Wexner Medical Center Department of Medicine Division of Gastroenterology Hepatology and Nutrition Ohio State University Wexner Medical Center Department of Medicine Division of Internal Medicine Ohio State University Wexner Medical Center Department of Medicine Division of Gastroenterology Hepatology and Nutrition Ohio State Uni- versity Wexner Medical Center Department of Pathology Ohio State University Wexner Medical Center

Post transplant lymphoproliferative disorder (PTLD) represents a life threatening disorder occurring after transplantation, ranging from a polyclonal mononucleo- sis like illness to a monomorphic high grade neoplasm with cytologic and histopathologic evidence indica- tive of transformation to lymphoma. PTLD of diffuse large B-cell lymphoma (DLBCL) subtype, isolated to the esophagus is a rare diagnosis. We describe the first case of an immunocompromised adult patient diagnosed with DLBCL-PTLD limited to his esophagus without an associated mass or locoregional lymphade-nopathy on imaging since the institution of the revised Cheson criteria, which includes positron emission tomography-computed tomography as the standard staging modality. Even more unique to our case was the suggestion of underlying cytomegalovirus (CMV) gastritis leading to a hypothesis about a less well understood relationship between CMV and Epstein Barr virus (EBV). In the post transplant setting, im- munocompromised state, or EBV positive state, upper gastrointestinal symptoms should prompt investigation with an upper endoscopy (EGD). Additionally, specific to our case, the fact that the patients' presentation was suspicious for CMV gastritis raises the possibility that the CMV infection predated his PTLD increasing his risk of acquiring PTLD. This reemphasizes the im- portance and diagnostic utility of early screening with EGD in patients after transplantation.

关键词： B-cell lymphoma Esophageal Lymphopro-liferative Post-transplant Epstein barr virus

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北极圈之梦与南森北极钻探计划

海洋地质动态 2004年第9期20卷 23-27页

作者： andrea johnson 许冬王汝建

冰雪覆盖的北冰洋，在阻挡考察者数十年后，将成为最后一个被科学钻探组织征服的大盆地。对高纬度北极地区钻孔进行成功的再现将是可与人类登月相比拟的海洋盛事。仍覆盖着神秘面纱的这片冰冻的海洋，将是首次开展的综合大洋钻探计划(IO... 详细信息

冰雪覆盖的北冰洋，在阻挡考察者数十年后，将成为最后一个被科学钻探组织征服的大盆地。对高纬度北极地区钻孔进行成功的再现将是可与人类登月相比拟的海洋盛事。仍覆盖着神秘面纱的这片冰冻的海洋，将是首次开展的综合大洋钻探计划(IODP)最先涉足的地方之一，将宣告科学探索新时代的到来。

关键词：北极圈北冰洋钻探科学考察

Flow behavior and fracture of Al−Mg−Si alloy at cryogenic temperatures

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Transactions of Nonferrous Metals Society of China 2021年第3期31卷 595-608页

作者： Danielle Cristina Camilo MAGALhAES andrea Madeira KLIAUGA Vitor Luiz SORDI Department of Materials Engineering Federal University of Sao Carlos−UFSCarRod.Washington Luizkm 23513565-905Sao Carlos–SPBrazil

The tensile and fracture behaviors of AA6061 alloy were investigated in order to provide quantitative data about this alloy at cryogenic *** of AA6061 alloy were solution heat treated before tensile tests at 298,173 and 77 K and tested at strain rates in the range from 0.1 to 0.0001 s^(−1).The results indicate the suppression of the Portevin−Le Chatelier(PLC)effect and dynamic strain aging(DSA)at 77 *** contrast,at 298 K,a remarkable serrated flow,characteristic of the PLC effect,is ***,the tensile behavior at 77 K,compared with that observed at 173 and 298 K,shows a simultaneous increase in strength,uniform elongation,modulus of toughness,strain-hardening exponent and strain rate sensitivity,which is related to a decrease in the dynamic recovery rate at low *** responses are reflected on the fracture morphology,since the dimple size decreases at 77 K,while the area covered by dimples *** of the johnson−Cook model show that a good agreement can be obtained for tests at 173 and 77 K,in which DSA is suppressed.

关键词： cryogenic temperature aluminum alloy flow behavior strain rate sensitivity work-hardening behavior johnson−Cook model fracture

*** the link between reduced reading ability and cognitive decline in older adults with acquired vision impairment:a feasibility study

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Annals of Eye Science 2019年第1期 204-204页

作者： Swaathi Balaji Karine Elalouf andrea Urqueta-Alfaro Julie-Andrée Marinier Aaron johnson Natalie Phillips Eva Kehayia M.Kathy Pichora-Fuller Walter Wittich École d'Optométrie Universitéde MontréalMontréalQCCanada Centre de recherche interdisciplinaire en réadaptation du Montréal métropolitain MontrealQCCanada Department of Psychology Concordia UniversityMontréalQCCanada School of Physical and Occupational Therapy McGill UniveristyMontréalQCCanada Department of Psychology University of Toronto at MississaugaMississaugaOntarioCanada

Background:Reading enables us to obtain information,to engage in leisure,educational,business and other activities,and fosters cognitive *** vision loss can have a negative effect on an individual’s ability to read,and,by extension,reduce overall quality of *** addition,a growing body of research on the association between reading and cognition has linked a decrease in reading ability with negative changes in cognitive ***,the purpose of the current study is to test the feasibility of a research protocol that will be used to study the association between reduced reading ability and cognitive impairment,specifically in older adults with acquired vision ***:Seven participants(age range,27-60 years,Mage=44,4 males)completed a series of questionnaires and assessments that measured their cognitive,hearing,and reading *** participants had normal hearing,vision and cognition,with the exception of one(two pre-existing hearing conditions).Cognition was tested using the Rey Auditory Verbal Learning Test(RAVLT),the RAVLT 50-word Recognition test,the Verbal Fluency Test,an auditory Trail-Making task,and an auditory 1-N-back memory *** was used to assess ear health,and hearing was measured with self-administered computerized audiometry(home hearing Test)and a speech-in-noise test(Canadian Digit Triplet Test).Questionnaires included the hearing handicap Inventory for the Elderly,and a multiple-choice questionnaire on subjective reading ability and reading ***,reading acuity,speed and comprehension were assessed using the International Reading Speed Texts and the ***:In testing the feasibility of this protocol,the uninterrupted length of testing time,including obtaining consent,was determined to be between 60-90 *** of the assessments and tests(RAVLT,MNRead,audiogram)were reported to be mentally ***,all pilot participants were able to complete all *** the exception of s

关键词： Cognition vision impairment reading rehabilitation