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Standard precaution measurements during ophthalmology practice in the pandemic stage of COVId-19

International Journal of Ophthalmology(English edition) 2020年第7期13卷 1017-1022页

作者： Ahm.d.moham.d.Reda Wael m.Ahmed department of ophthalmology Faculty of MedicineAin Sham UniversityCairo 11566Egypt dar Eloyoun Eye Laser Centers Muscat 118Oman

AIm:To take specific precautions and keep a safe practice during providing ophthalmology health services without compromising the patient’s safety as well as the team workers and the community in the pandemic stage of corona virus disease 2019(COVId-19).mETHOdS:Applying patient circulation scheme implemented in our ophthalmology centers with the guidance of ministry of health infection control guidelines star ted from the moment that we receive a call or Whats App message or Facebook inquiry from patients until 21 d after patients first visit if *** directions were ***,community awareness of the disease and the ophthalmology related advices in how eye can transfers the infection and how to protect our eyes not to be infected through videos interviews of our consultants and distribution in social m.d.a like Instagram,Facebook,Whats App pages radio and TV interviews as well as leaflet health awareness for distribution for ***,scheduling of patients’appointments to prevent overcrowdings and cross ***,protective measurements tools in the center to detect and prevent any exposure of the patients to patients and to protect m.d.cal staff,COVId-19 scoring system was set up to identify patients with fever,respiratory symptoms,acute conjunctivitis or recent travel to outbreak areas and to encourage these individuals to postpone their appointments for at least 21 *** use of personal protective equipment was *** all the elective surgeries keeping only the emergency types advised by fourth:how to deal with our patients if they need an urgent ophthalmological intervention and how to deal with suspected cases of corona if any cases ***:Our measures helped our colleagues to try to keep providing ophthalmology health services without increasing the incidence of infection for COVId-19 until this pandemic is ***:In our practice,ophthalmologists should work with new aura of social m.d.a to facilitate the

关键词： corona virus COVId-19 Instagram Facebook WhatsApp personal protective equipment

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Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor^(■) RH40 using experimental design

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Asian Journal of Pharmaceutical Sciences 2018年第6期13卷 536-545页

作者： Thuy Tran Thomas Rades Anette müllertz department of Pharmacy Faculty of Health and Medical Sciences University of Copenhagen Bioneer: FARmA Faculty of Health and Medical Sciences University of Copenhagen

The development of self-nanoemulsifying drug delivery systems(SNEddS) to enhance the oral bioavailability of lipophilic drugs is usually based on traditional one-factor-at-a-time approaches. These approaches may be inadequate to analyse the effect of each excipient and their potential interactions on the emulsion droplet size form.d.when dispersing the SNEddS in an aqueous environment. The current study investigates the emulsion droplet sizes form.d.from SNEddS containing different levels of the natural surfactant monoacyl phosphatidylcholine to reduce the concentration of the synthetic surfactant polyoxyl 40 hydrogenated castor oil(Kolliphor ~? RH40). monoacyl phosphatidylcholine was used in the form of Lipoid S LPC 80(LPC, containing approximately 80% monoacyl phosphatidylcholine, 13% phosphatidylcholine and 4% concomitant components). The investigated SNEddS comprised of long-chain or m.d.um-chain glycerides(40% to 75%), Kolliphor ~? RH40(5% to 55%), LPC(0 to 40%) and ethanol(0 to 10%). d-optimal design, multiple linear regression, and partial least square regression were used to screen different SNEddS within the investigated excipient ranges and to analyse the effect of each excipient on the resulting droplet size of the dispersed SNEddS measured by dynamic light scattering. All investigated formulations form.d.nano-emulsions with droplet sizes from about 20 to 200 nm. The use of m.d.umchain glycerides was more likely to result in smaller and more monodisperse droplet sizes compared to the use of long-chain glycerides. Kolliphor~? RH40 exhibited the most significant effect on reducing the emulsion droplet sizes. Increasing LPC concentration increased the emulsion droplet sizes, possibly because of the reduction of Kolliphor~? RH40 concentration. A higher concentration of ethanol resulted in an insignificant reduction of the emulsion droplet size. The study provides different ternary diagrams of SNEddS containing LPC and Kolliphor ~? RH40 as a reference for form

关键词： monoacyl phosphatidylcholine Self-nanoemulsifying drug delivery systems d-optimal design Polyoxyl 40 hydrogenated castor oil Kolliphor^(■)(RH40) droplet size Cryogenic transmission electron microscopy

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Pottery glaze——An excellent adsorbent for the removal of Cu(Ⅱ) from aqueous solution

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Chinese Journal Of Geochemistry 2012年第2期31卷 136-146页

作者： Rifaqat Ali Khan Rao m.Kashifuddin Environmental Research Laboratory Department of Applied ChemistryFaculty of Engineering and TechnologyAligarh Muslim University

In the present study,pottery glaze was investigated as an excellent adsorbent for the removal of Cu(Ⅱ) ions from aqueous *** of concentration,contact time,pH,and effect of electrolyte concentration,adsorbent doses and temperature were studied by using batch process to optimize conditions for maximum adsorption. Equilibrium isotherm.d.ta were analyzed using Langmuir,Freundlich and Temkin isotherms at 30,40 and 50℃. Therm.d.namic parameters such as standard enthalpy change(ΔH0),free energy change(ΔG 0)and entropy change (ΔS0)were also *** parameters indicated that adsorption process is endothermic and spontaneous in *** mean energy calculated from.d.binin-Radushkeuich(d-R)isotherms showed chemical nature of *** kinetic data were evaluated using the pseudo-first-order and pseudo-second order kinetic equations and it was found that data best fitted pseudo-second-order m.d.l over a wide range of initial Cu(Ⅱ)concentrations supporting that chemisorption process was *** adsorption and desorption studies carried out by batch process suggested 100% desorption of Cu(Ⅱ)ions with 0.1 N HCl solution.

关键词：吸附剂水溶液除铜陶器 Langmuir 电解质浓度批处理过程釉

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钆对比剂过敏反应和降低后续过敏反应发生率的策略:系统综述和meta分析

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国际医学放射学杂志 2020年第5期 614-615页

作者： d.T.Walker m.S.davenport T.A.mcGrath m.d.F.mcInnes T.Shankar N.Schieda 刘思睿 department of m.d.cal Imaging The Ottawa Hospital

摘要皮质激素使用后发生钆类对比剂(GBCA)过敏反应的机制尚不清楚。目的根据GBCA类别确定GBCA过敏反应总体发生率,并确定使用替代GBCA或皮试对过敏反应

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足尺磁流变阻尼器的建模及动态特性

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地震工程与工程振动 2001年第S1期21卷 8-23页

作者：杨广强 B.F SpencerJr J.d.Carlson m.K. Sain 美国圣母大学土木及地质工程系 notrdarnein46556 美国LORd公司美国圣母大学电气工程系 notredamein46556

在过去三十年左右的时间里，结构保护系统受到了广大研究者的普遍关注。这种保护系统可以用来降低自然灾害（如地震、强风）对土木工程建筑的损害。由于磁流变阻尼器机械结构简单，动态范围大，能耗低、回复力大，鲁棒性良好，能够在满... 详细信息

在过去三十年左右的时间里，结构保护系统受到了广大研究者的普遍关注。这种保护系统可以用来降低自然灾害（如地震、强风）对土木工程建筑的损害。由于磁流变阻尼器机械结构简单，动态范围大，能耗低、回复力大，鲁棒性良好，能够在满足不同工程项目需求的同时提供有效的结构抗震抗风手段，目前它是一种非常有前途的半主动结构减震装置。本文首先介绍了磁流变液体和装置的主要特性和优点，建立了磁流变阻尼器的伪静力轴对称模型．并将其结果和平行板模型以及阻尼器实验结果进行了比较。尽管伪静力模型对于阻尼器的设计十分有效，但是它们还不足以描述阻尼器的动态特性。对实际工程应用来说，动态响应时间是一项非常重要的性能指标。文章还讨论了影响磁流变阻尼器动态响应时间的因素，建立了基于Ｂｏｕｃ—Ｗｅｎ模型的阻尼器动态模型。同时文章也提出了优化阻尼器动态响应的途径和方法以及其实验验证。

关键词：磁流变液体磁流变阻尼器阻尼器智能阻尼装置智能材料滞回模型参数识别系统辨识流变技术

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Parallel Algebraic multigrid methods in Gyrokinetic Turbulence Simulations

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Communications in Computational Physics 2007年第5期2卷 881-899页

作者： m.F.Adams Y.Nishimura Columbia University APAM500 W.120th St.Rm 200MC 4701New YorkNY 10027USA department of Physics and Astronomy University of CaliforniaIrvineCA 92697-4575USA.

Parallel algebraic multigrid methods in gyrokinetic turbulence simulations are *** equations of the elliptic operator−■^(2)u+αu=f(with bothα=0 and α≠0)are ubiquitous in magnetically confined fusion plasma ***αis equal to zero a“pure”Laplacian or Poisson equation results and whenαis greater than zero a so called Helmholtz equation is *** a gyrokinetic turbulence simulation m.d.l as a testbed,we investigate the performance characteristics of basic classes of linear solvers(direct,one-level iterative,and multilevel iterative methods)on 2d unstructured finite element method(FEm)problems for both the Poisson and the Helmholtz equations.

关键词： Algebraic multigrid gyrokinetic Poisson equation particle in cell simulation.

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Helicobacter pylori vacA s1a and s1b alleles from clinical isolates from.d.fferent regions of Chile show a distinct geographic distribution

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World Journal of Gastroenterology 2005年第40期11卷 6366-6372页

作者： mI díaz A Valdivia P martínez JL Palacios P Harris J Novales E Garrido d Valderrama C Shilling A Kirberg E Hebel J Fierro R Bravo F Siegel G Leon G Klapp A Venegas departamento de Genética molecular y microbiología. Pontificia Universidad Católica de Chile. Santiago departamento de Pediatría Centro de diagnóstico Terapéutico Los Angeles Unidad de Gastroenterología Anatomía Patológica Centro de Endoscopía Quirúrgica Hospital Base de Linares Hospital Regional de Valdivia Instituto de Bioquímica Hospital Regional de Punta Arenas

AIm： To establish the most common vacA alleles in Helicobacter pylori （ H pylon） strains isolated from Chilean patients and its relationship with gastritis and gastroduodenal ulcers, mETHOdS： Two hundred and forty five Hpyloriclinical isolates were obtained from 79 biopsies from Chilean infected patients suffedng from gastrointestinal diseases. An average of 2-3 strains per patient was isolated and the vac4 genotype was analyzed by PCR and 3% agarose electrophoresis. Some genotypes were checked by dNA sequencing. RESULTS： The most prevalent vacA genotype in Chilean patients was slb ml （76%）, followed by sla ml （21%）. In oontrast, the s2 m2 genotype was scarcely represented （3%）. The slb ml genotype was found most frequently linked to gastropathies （P〈0.05） rather than ulcers. Ulcers were found more commonly in male and older patients. Curiously, patents Imng in dties located North and far South of Santiago, thecapital and largest Chilean city, carried almost exclusively strains with the slb ml genotype. In contrast, patients from Santiago and cities located South of Santiago carded strains with either one or both sla ml and slb ml genotypes. Regarding the s2 m2 genotype, comparison with GenBank sequences revealed that Chilean s2 sequence was identical to those of Australian, American, and Colombian strains but quite different from those of Alaska and India. CONCLUSION： differences in geographic distribution of the s and m vacA alleles in Chile and a relationship of slb ml genotype with gastritis were found. Sequence data in part support a hispanic origin for the vacA genotype. Asymmetric distribution of genotypes slb ml and s2 m2 recedes H Pyloristrain distribution in Spain and Portugal.

关键词： Hpylori vacA alleles Chilean isolates s1 s2 m1 and m2 sequences

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microglia as hackers of the matrix:sculpting synapses and the extracellular space

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Cellular & molecular Immunology 2021年第11期18卷 2472-2488页

作者： Joshua d.Crapser miguel A.Arreola Kate I.Tsourmas Kim N.Green department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA

microglia shape the synaptic environment in health and disease,but synapses do not exist in a ***,pre-and postsynaptic terminals are surrounded by extracellular matrix(ECm),which together with glia comprise the four elements of the contemporary tetrapartite synapse *** research in this area is still just beginning,accumulating evidence points toward a novel role for microglia in regulating the ECm.d.ring normal brain homeostasis,and such processes may,in turn,become dysfunctional in *** it relates to synapses,microglia are reported to m.d.fy the perisynaptic matrix,which is the diffuse matrix that surrounds dendritic and axonal terminals,as well as perineuronal nets(PNNs),specialized reticular formations of compact ECm that enwrap neuronal subsets and stabilize proximal *** interconnected relationship between synapses and the ECm in which they are embedded suggests that alterations in one structure necessarily affect the dynamics of the other,and microglia may need to sculpt the matrix to m.d.fy the synapses ***,we provide an overview of the microglial regulation of synapses,perisynaptic matrix,and PNNs,propose candidate mechanisms by which these structures may be m.d.fied,and present the implications of such m.d.fications in normal brain homeostasis and in disease.

关键词： Neuroscience Perineuronal nets microglia Extracellular matrix Neuroinflammation

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梯度洗脱液相色谱的智能优化

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中国科学（B辑） 1991年第11期22卷 1130-1138页

作者：林炳承刘文烨卢佩章 d.L.massart m.d..Smet 中国科学院大连化学物理研究所大连116012 布鲁塞尔弗里大学

本文从被测组分的分子结构和其差异入手,通过对梯度状态下柱内过程的描述,保留值和宽度的预测,讨论了梯度洗脱液相色谱的一种优化方法。

关键词：液相色谱梯度洗脱手性药物分离

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Power Laws and Skew distributions

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Communications in Computational Physics 2012年第8期12卷 721-731页

作者： Reinhard mahnke Jevgenijs Kaupuzs mãrtins Brics Institute of Physics Rostock UniversityD-18051 RostockGermany Institute of mathematics and Computer Science University of LatviaLV-1459 RigaLatvia

Power-law distributions and other skew distributions,observed in various m.d.ls and real systems,are considered.A m.d.l,describing evolving systems with increasing number of elements,is considered to study the distribution over element *** power-law distributions are *** non-stationary skew distributions are obtained and analyzed,based on exact solutions and numerical simulations.

关键词： Power law critical exponent evolving system skew distribution

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