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环球科学 2017年第10期 19-19页

作者：安德里亚·马克斯(andrea Marks) 李想

触摸式导航地图可以帮助盲人穿过日趋复杂的交通路口。

关键词：盲人地图触觉技术

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国际视野下的数字人文教育

术前计划与磁共振纤维束成像在颅脑肿瘤切除中的应用

图书馆学情报学 2020年第9期

作者： Tanja Wissik Jennifer Edmond Frank Fischer Franciska de Jong Stefania Scagliola andrea Scharnhorst Hendrik Schmeer Walter Scholger Leon Wessels

数字人文以其新实践、新途径和新方法丰富了传统的人文学科领域。进入21世纪以来，暑期学校、研讨会和其他类似形式的教育活动普及了一系列与之相关的必备技能，以保证学生、学者们能够把握数字时代的新机会，同时世界各地推出了越来越... 详细信息

数字人文以其新实践、新途径和新方法丰富了传统的人文学科领域。进入21世纪以来，暑期学校、研讨会和其他类似形式的教育活动普及了一系列与之相关的必备技能，以保证学生、学者们能够把握数字时代的新机会，同时世界各地推出了越来越多相关的学士和硕士项目。本文论述的焦点——数字人文课程登记中心(Digital Humanities Course Registry，DHCR)的创建就是为了展现全球日益兴盛的数字人文教育状况，其使命是广泛收集同类课程的资料，提供数字人文领域教学和培训的最新动态。文章探讨了数字人文这一新兴领域，并对CLARIN和DARIAH这两个欧洲基础设施进行介绍——它们是DHCR的共同运营者。文中还具体描述了DHCR的数据模型和数据管护流程，简要介绍其历史。利用DHCR实时数据，以定量方式描绘了数字人文教学的国际格局。

关键词：数字人文教学教育登记中心研究基础设施

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国际医学放射学杂志 2010年第1期 95-95页

作者： A.Romano G.D'andrea G.Minniti L.Mastronardi L.Ferrante L.Fantozzi 赵峰 Department of Neuroradiology S.Andrea HospitalUniversity SapienzaVia di Grottarossa 103500189RomeItaly

本研究目的为①评价辨别纤维束轨迹的可能性;②观察神经导航系统在术前计划中的应用;③评估病人在术前与术后的临床情况;④评价手术计划及手术过程中这种信息的作用。前瞻性的序贯研究28例右利手病人。所有病人由神经科医生在术前与术... 详细信息

本研究目的为①评价辨别纤维束轨迹的可能性;②观察神经导航系统在术前计划中的应用;③评估病人在术前与术后的临床情况;④评价手术计划及手术过程中这种信息的作用。前瞻性的序贯研究28例右利手病人。所有病人由神经科医生在术前与术后阶段进行临床评估。重建分离的椎体束、视辐射和弓形神

关键词：纤维束术前计划神经导航系统磁共振

产前应激及炎症相关基因的甲基化水平对儿童早期肥胖指标影响的队...

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Renal function assessment in atrial fibrillation:Usefulness of chronic kidney disease epidemiology collaboration vs reexpressed 4 variable modification of diet in renal disease

2017环境与公共健康学术会议暨中国环境科学学会环境医学与健康分会、中国毒理学会生化与分子毒理专业委员会2017年年会

作者： Shaowei Wu Chris Gennings Rosalind J.Wright ander Wilson Heather H.Burris Allan C.Just Joseph M.Braun Katherine Svensson Jia Zhong Kasey J.M.Brennan Alexandra Dereix Alejandra Cantoral Lourdes Schnaas Martha Maria Tellez-Rojo Robert O.Wright andrea A.Baccarelli Department of Occupational and Environmental Health Sciences School of Public HealthPeking University Population Health and Science Policy Mount Sinai Hospital The Mindich Child Health & Development Institute Icahn School of Medicine at Mount Sinai Department of Statistics Colorado State University Department of Neonatology and Obstetrics Gynecology and Reproductive BiologyBeth Israel Deaconess Medical CenterHarvard Medical School Department of Preventive Medicine Icahn School of Medicine at Mount Sinai Department of Epidemiology School of Public HealthBrown University Department of Environmental Health Sciences Mailman School of Public HealthColumbia University

Background:Maternal stress during pregnancy may influence childhood growth and adiposity,possibly through immune/inflammatory *** investigated whether exposure to prenatal stress and methylation in inflammation-related genes were associated with childhood adiposity in424 mother-child pairs in Mexico City,***:A stress index was created based on four

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World Journal of Cardiology 2015年第10期7卷 685-694页

作者： Rami Riziq-Yousef Abumuaileq Emad Abu-Assi andrea López-López Sergio Raposeiras-Roubin Moisés Rodríguez-Manero Luis Martínez-Sande Francisco Javier García-Seara Xesus Alberte Fernandez-López Jose Ramón González-Juanatey Cardiology Department University Clinical Hospital of Santiago de Compostela

AIM: To compare the performance of the re-expressed Modification of Diet in Renal Disease equation vs the new Chronic Kidney Disease Epidemiology Collaboration equation in patients with non-valvular atrial ***: We studied 911 consecutive patients with non-valvular atrial fibrillation on vitamin-K antagonist. The performance of the re-expressed Modification of Diet in Renal Disease equation vs the new Chronic Kidney Disease Epidemiology Collaboration equation in patients with non-valvular atrial fibrillation with respect to either a composite endpoint of major bleeding, thromboembolic events and all-cause mortality or each individual component of the composite endpoint was assessed using continuous and categorical ≥ 60, 59-30, and < 30 m L/min per 1.73 m2 estimated glomerular filtration ***: During 10 ± 3 mo, the composite endpoint occurred in 98(10.8%) patients: 30 patients developed major bleeding, 18 had thromboembolic events, and 60 died. The new equation provided lower prevalence of renal dysfunction < 60 m L/min per 1.73 m2(32.9%),compared with the re-expressed equation(34.1%). Estimated glomerular filtration rate from both equations was independent predictor of composite endpoint(HR = 0.98 and 0.97 for the re-expressed and the new equation, respectively; P < 0.0001) and all-cause mortality(HR = 0.98 for both equations, P < 0.01). Strong association with thromboembolic events was observed only when estimated glomerular filtration rate was < 30 m L/min per 1.73 m2: HR is 5.1 for the re-expressed equation, and HR = 5.0 for the new equation. No significant association with major bleeding was observed for both ***: The new equation reduced the prevalence of renal dysfunction. Both equations performed similarly in predicting major adverse outcomes.

关键词： Atrial fibrillation Anticoagulants Follow-up studies Kidney Prognosis

The Faces of Fungi database:fungal names linked with morphology,phylogeny and human impacts

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Fungal Diversity 2015年第5期74卷 3-18页

作者： Subashini C.Jayasiri Kevin D.Hyde Hiran A.Ariyawansa Jayarama Bhat Bart Buyck Lei Cai Yu-Cheng Dai Kamel A.Abd-Elsalam Damien Ertz Iman Hidayat Rajesh Jeewon E.B.Gareth Jones Ali H.Bahkali Samantha C.Karunarathna Jian-Kui Liu J.Jennifer Luangsa-ard H.Thorsten Lumbsch Sajeewa S.N.Maharachchikumbura Eric H.C.McKenzie Jean-Marc Moncalvo Masoomeh Ghobad-Nejhad Henrik Nilsson Ka-Lai Pang Olinto L.Pereira Alan J.L.Phillips Olivier Raspé Adam W.Rollins andrea I.Romero Javier Etayo Faruk Selçuk Steven L.Stephenson Satinee Suetrong Joanne E.Taylor Clement K.M.Tsui Alfredo Vizzini Mohamed A.Abdel-Wahab Ting-Chi Wen Saranyaphat Boonmee Dong Qin Dai Dinushani A.Daranagama Asha J.Dissanayake Anusha H.Ekanayaka S.C.Fryar Sinang Hongsanan Ruvishika S.Jayawardena Wen-Jing Li Rekhani H.Perera R.Phookamsak Nimali Ide Silva Kasun M.T.hambugala Qing Tian Nalin N.Wijayawardene Rui-Lin Zhao Qi Zhao Ji-Chuan Kang Itthayakorn Promputtha Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agro forestry Centre East and Central Asia Office 132 Lanhei RoadKunming 650201China Botany and Microbiology Department College of ScienceKing Saud UniversityRiyadh 1145Saudi Arabia Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha403108 GoaIndia Department of Botany Goa UniversityGoa 403206India Muséum National d’Histoire Naturelle Département Systématique et EvolutionCP 39ISYEBUMR 7205 CNRS MNHN UPMC EPHE12 Rue BuffonF-75005 ParisFrance State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesWest Beicheng RdBeijingChina Institute of Microbiology Beijing Forestry UniversityPO Box 61Beijing 100083China Plant Pathology Research Institute Agricultural Research Center(ARC)12619 GizaEgypt Botanic Garden Meise Department Bryophytes-Thallophytes(BT)Nieuwelaan 38B-1860 MeiseBelgium Fédération Wallonie-Bruxelles Direction Générale de l’Enseignement non obligatoire et de la Recherche scientifiqueRue A.Lavallée 11080 BruxellesBelgium Microbiology Division Research Center for BiologyIndonesian Institute of Sciences(LIPI)Jl.Raya Jakarta-Bogor KM 46Cibinong 16911West JavaIndonesia Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Science&Education The Field Museum1400 S.Lake Shore DriveChicagoIL 60605USA Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand Department of Natural History Royal Ontario Museumand Department of Ecology and Evolutionary BiologyUniversity of Toronto100 Queen’s ParkTorontoON M5S2C6Canada Department of Biotechnology Iranian Research Organiza

Taxonomic names are key links between various databases that store information on different *** global fungal nomenclural and taxonomic databases(notably Index Fungorum,Species Fungorum and MycoBank)can be sourced to find taxonomic details about fungi,while DNA sequence data can be sourced from NCBI,EBI and UNITE *** the sequence data may be linked to a name,the quality of the metadata is variable and generally there is no corresponding link to images,descriptions or herbarium *** is generally no way to establish the accuracy of the names in these genomic databases,other than whether the submission is from a reputable *** tackle this problem,a new database(FacesofFungi),accessible at ***(FoF)has been *** fungal database allows deposition of taxonomic data,phenotypic details and other useful data,which will enhance our current taxonomic understanding and ultimately enable mycologists to gain better and updated insights into the current fungal classification *** addition,the database will also allow access to comprehensive metadata including descriptions of voucher and type *** database is user-friendly,providing links and easy access between taxonomic ranks,with the classification system based primarily on molecular data(from the literature and via updated web-based phylogenetic trees),and to a lesser extent on morphological data when molecular data are *** FoF species are not only linked to the closest phylogenetic representatives,but also relevant data is provided,wherever available,on various applied aspects,such as ecological,industrial,quarantine and chemical *** data include the three main fungal groups(Ascomycota,Basidiomycota,Basal fungi)and fungus-like *** FoF webpage is an output funded by the Mushroom Research Foundation which is an NGO with seven directors with mycological *** webpage has 76 curators,and with the help of these s

关键词： Classification Database Faces of Fungi Fungi Phylogeny Taxonomy

Nature：研究鉴定出侵袭性胰腺癌细胞及其弱点

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现代生物医学进展 2017年第14期17卷 I0002-I0003页

作者： Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda Univ Texas MD Anderson Canc Ctr Dept Genom Med Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Inst Appl Canc Sci Houston TX 77030 USA European Inst Oncol I-20141 Milan Italy Sun Yat Sen Univ Ctr Canc State Key Lab Oncol South China Guangzhou 510060 Guangdong Peoples R China Univ Cattolica Sacro Cuore Ist Patol Gen I-00168 Rome Italy Baylor Coll Med Grad Program Struct & Computat Biol & Mol Biophys Houston TX 77030 USA Johns Hopkins Univ Sol Goldman Pancreat Canc Res Ctr Dept Pathol Baltimore MD 21287 USA Univ Texas MD Anderson Canc Ctr Dept Mol & Cellular Oncol Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Translat Mol Pathol Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Leukemia Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Off Technol Commercializat Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Canc Syst Imaging Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Canc Biol Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Expt Therapeut Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr ORBIT Platform Houston TX 77030 USA Univ Texas MD Anderson Canc Ctr Dept Surg Oncol Houston TX 77030 USA Friedrich Alexander Univ Erlangen Nuremberg Univ Hosp Dept Pathol D-91054 Erlangen Germany Friedrich Alexander Univ Erlangen Nuremberg Dept Pathol D-91054 Erlangen Germany Friedrich Alexander Univ Erlangen Nuremberg Sheikh Ahmed Bin Zayed Nahyan Ctr Pancreat Canc R D-91054 Erlangen Germany St Jude Childrens Res Hosp Ctr Comprehens Canc Memphis TN 77027 USA St Jude Childrens Res Hosp Dept Oncol Memphis TN 77027 USA C4 Therapeut Cambridge MA 02142 USA Univ Texas Syst Inst Hlth Transformat Austin TX 78701 USA

在一项新的研究中，来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植（patient—derived tumorxenograft,PDx）和模式小鼠开展一系列临床前实验，鉴定出一种门卫蛋白（gatekee Perprotein）阻止胰腺癌细胞转化为... 详细信息

在一项新的研究中，来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植（patient—derived tumorxenograft,PDx）和模式小鼠开展一系列临床前实验，鉴定出一种门卫蛋白（gatekee Perprotein）阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型，并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。

关键词：胰腺癌癌细胞侵袭性鉴定异种移植研究人员细胞类型细胞转化

肿瘤病人FDGPET及分次团注多层螺旋CT融合成像的初步研究

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国际医学放射学杂志 2016年第3期 306-306页

作者： M.Scialpi I.Palumbo S.Gravante T.Buresta A.D’andrea L.Pierotti 曾繁勇 Department of Surgical and Biomedical Sciences Division of Radiology 2Perugia UniversityS.Mariadella Misericordia Hospital

摘要目的评估分次团注多层螺旋CT结合18F-FDG PET融合成像技术在肿瘤病人随访中的价值。材料与方法本研究征得医院伦理委员会同意。38例行FDG PET/非增强CT检查以及分次团注增强多层螺旋CT检查用于再分期的肿瘤病人被纳入本回顾性分析... 详细信息

摘要目的评估分次团注多层螺旋CT结合18F-FDG PET融合成像技术在肿瘤病人随访中的价值。材料与方法本研究征得医院伦理委员会同意。38例行FDG PET/非增强CT检查以及分次团注增强多层螺旋CT检查用于再分期的肿瘤病人被纳入本回顾性分析。分次团注CT检查方案包含

关键词：团注分次 FDGPET 融合成像 CT 多层螺旋肿瘤病人

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循证医学：乳房再造

中国美容整形外科杂志 2014年第12期25卷 I0016-I0016页

作者： Toni Zhong Colleen M. McCarthy Alison N. Price andrea L. Pusic 朱利娜高景恒张晨袁继龙多伦多大学加拿大安大略省多伦多斯隆凯特林癌症纪念中心纽约《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科辽宁省人民医院整形外科

学习目标通过学习本文，读者可以达到以下目的：①识别乳房再造可用的各种手术方法；②对有乳房再造需求的患者进行综合的评估；③获得关于不同乳房再造方法适应证和禁忌证的知识；④理解不同乳房再造方法所固有的并发症；⑤总结术后长... 详细信息

学习目标通过学习本文，读者可以达到以下目的：①识别乳房再造可用的各种手术方法；②对有乳房再造需求的患者进行综合的评估；③获得关于不同乳房再造方法适应证和禁忌证的知识；④理解不同乳房再造方法所固有的并发症；⑤总结术后长期主观和客观的影响。概要本文内容是美国整形外科委员会资格认证维护项目继续外科学教育考核评估内容。本文的目的是概述乳腺切除术后乳房畸形的诊治方法。

关键词：乳房再造循证医学学习目标考核评估切除术后外科学教育手术方法资格认证

一项在HBeAg阳性、慢性乙型肝炎(CHB)患者中比较磷丙替诺福韦(TAF)与富马酸替诺福韦二吡呋酯(TDF)的3期研究:96周时疗效和安全性结果

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一项在HBeAg阳性、慢性乙型肝炎(CHB)患者中比较磷丙替诺福韦(TAF...