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Revision of the Conodont Mockina slovakensis and Its Paleogeographic Implications for the Upper Triassic Intraplatform Basins of the Alps

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Journal of Earth Science 2021年第3期32卷 657-666页

作者： Yixing Du Viktor Karadi Guido Roghi Maurizio Ponton andrea cozzi Manuel Rigo Department of Geosciences University of Padova35131 PadovaItaly Department of Palaeontology Eotvos Lorand UniversityBudapest 1117Hungary Institute of Geosciences and Earth Resources National Research Council of Italy35131 PadovaItaly Department of Mathematics and Geosciences University of Trieste34128 TriesteItaly Eni Sharjah B.V 73500 SharjahUnited Arab Emirates

Mockina slovakensis,thought to have evolved from Epigondolella praeslovakensis,is an important species of the Norian(Upper Triassic),generally considered as the representative of the uppermost Alaunian to upper Sevatian in the Tethys.The previous description of M.slovakensis was incomplete,thus has led to some misidentifications.We thus update the description of M.slovakensis and discuss its comparisons and occurrence based on the new conodont investigations in Dolomia di Forni and the data from previous literatures.The conodont assemblage in the succession of Dolomia di Forni is dominated by M.slovakensis,along with rare M.postera and E.praeslovakensis.We described two morphotypes of M.slovakensis(morphotypes A and B),on the basis of shape of the lateral profile.These two morphotypes can also be observed in the E.praeslovakensis.Moreover,M.slovakensis is usually documented as almost monospecific conodont association in intraplatform basins,thus its paleogeographic implications are also discussed.

关键词： Mockina conodont morphotype intraplatform basin

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Clinical epidemiology of chronic viral hepatitis B:A Tuscany real-world large-scale cohort study

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World Journal of Hepatology 2018年第5期10卷 409-416页

作者： Cristina Stasi Caterina Silvestri Roberto Berni Maurizia Rossana Brunetto Anna Linda Zignego Cristina Orsini Stefano Milani Liana Ricciardi andrea De Luca Pierluigi Blanc Cesira Nencioni Donatella Aquilini Alessandro Bartoloni Giampaolo Bresci Santino Marchi Franco Filipponi Piero Colombatto Paolo Forte andrea Galli Sauro Luchi Silvia Chigiotti Alessandro Nerli Giampaolo Corti Rodolfo Sacco Paola Carrai Angelo Ricchiuti Massimo Giusti Paolo Almi andrea cozzi Silvia Carloppi Giacomo Laffi Fabio Voller Francesco Cipriani Observatory of Epidemiology Regional Health Agency of TuscanyFlorence 50141Italy Center for Systemic Manifestations of Hepatitis Viruses(MaSVE) Internal Medicine and Liver UnitDepartment of Experimental and Clinical MedicineCareggi University HospitalFlorence 50134Italy Web Solutions Data Visualization and Scientific DocumentationRegional Health Agency of TuscanyFlorence 50141Italy Hepatology Unit Department of Clinical and Experimental MedicineUniversity Hospital of PisaPisa 56100Italy Gastroenterology Research Unit Department of Experimental and Clinical Biomedical Sciences“Mario Serio”Careggi University HospitalFlorence 50134Italy Infectious Disease Unit Hospital of LuccaLucca 55100Italy Infectious Diseases Unit Department of Medical BiotechnologiesSiena University HospitalSiena 53100Italy Infectious Disease Unit “S.Maria Annunziata”HospitalPonte a Niccheri 50012Italy Infectious Disease Unit Hospital of GrossetoGrosseto 58100Italy Infectious Disease Unit Hospital of PratoPrato 59100Italy Infectious and Tropical Diseases Unit Department of Experimental and Clinical MedicineCareggi University HospitalFlorence 50134Italy Gastroenterology and Metabolic Disorders Department of SurgeryCisanello University HospitalPisa 56100Italy Gastroenterology Unit Department of Translational Research and New Technologies in Medicine and SurgeryCisanello University Hospital of PisaPisa 56100Italy Liver Surgery and Transplantation Unit Department of Surgical PathologyMedicineMolecular and Critical AreaCisanello University HospitalPisa 56100Italy Internal Medicine Unit “San Jacopo”HospitalPistoia 51100Italy Infectious Diseases and Hepatology Unit Department of Internal and Specialized MedicineUniversity Hospital of SienaSiena 53100Italy Gastroenterology Unit San Giuseppe HospitalEmpoli 50053Italy Internal Medicine and Liver Unit Department of Experimental and Clinical MedicineCareggi University HospitalFlorence 50135Italy Department of Prevention Central Tuscany Local UnitFlorence 5

AIM To build a regional database of chronic patients to define the clinical epidemiology of hepatitis B virus(HBV)-infected patients in the Tuscan public health care system.METHODS This study used a cross-sectional cohort design. We evaluated chronic viral hepatitis patients with HBV referred to the outpatient services of 16 hospital units. Information in the case report forms included main demographic data, blood chemistry data, viral hepatitis markers, instrumental evaluations, and eligibility for treatment or ongoing therapy and liver transplantation. RESULTS Of 4015 chronic viral hepatitis patients, 1096(27.3%) were HBV infected. The case report form was correctly completed for only 833 patients(64% males, 36% females; mean age 50.1 ± 15.4). Of these HBV-infected patients, 73% were Caucasian, 21% Asian, 4% Central African, 1% North African and 1% American. Stratifying patients by age and nationality, we found that 21.7% of HBV-infected patients were aged < 34 years(only 2.8% were Italian). The most represented routes of transmission were nosocomial/dental procedures(23%), mother-to-child(17%) and sexual transmission(12%). The most represented HBV genotypes were D(72%) and A(14%). Of the patients, 24.7% of patients were HBe Ag positive, and 75.3% were HBe Ag negative. Of the HBV patients 7% were anti-HDV positive. In the whole cohort, 26.9% were cirrhotic(35.8% aged < 45 years), and 47% were eligible for or currently undergoing treatment, of whom 41.9 % were cirrhotic. CONCLUSION Only 27.3% of chronic viral hepatitis patients were HBV infected. Our results provide evidence of HBV infection in people aged < 34 years, especially in the foreign population not protected by vaccination. In our cohort of patients, liver cirrhosis was also found in young adults.

关键词： Hepatitis B virus infection Liver fibrosis Cirrhosis Public health Epidemiology

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The Applications of Genome Editing in Xenotransplantation

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Journal of Genetics and Genomics 2016年第5期43卷 233-237页

作者： andrea Perota Irina Lagutina Corinne Quadalti Giovanna Lazzari Emanuele cozzi Cesare Galli Avantea Laboratory of Reproductive Technologies Cremona Italy Department of Veterinary Medical Sciences University of Bologna Italy Avantea Foundation Cremona Italy Transplant Immunology Unit Padua General Hospital Padua Italy

Higher living standards and better medical care are increasing the lifespan of people around the world.Aging populations,however,have an increased incidence of loss of function or failure of cell,tissue or organ.This has led to the development of new medical disciplines,such as organ transplantation and more recently regenerative medicine.

关键词： disciplines Genome populations enormous editing programmable incidence rejection targeting pancreas

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Intrinsic and Extrinsic Exciton Recombination Pathways in AgInS_(2)Colloidal Nanocrystals

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Energy Material Advances 2021年第1期2021卷 165-174页

作者： Matteo L.Zaffalon Valerio Pinchetti andrea Camellini Sergey Vikulov Chiara Capitani Bing Bai Meng Xu Francesco Meinardi Jiatao Zhang Liberato Manna Margherita Zavelani-Rossi Scott A.Crooker Sergio Brovelli Dipartimento di Scienza dei Materiali Universitàdegli studi di Milano-Bicoccavia Roberto Cozzi 5520125 MilanoItaly Dipartimento di Energia Politecnico di MilanoVia Ponzio 34/320133 MilanoItaly Istituto Italiano di Tecnologia Via Morego 3016163 GenovaItaly Glass to Power SpA Via Fortunato Zeni 838068 RoveretoItaly Beijing Key Laboratory of Construction-Tailorable Advanced Functional Materials and Green Applications School of Materials Science&EngineeringBeijing Institute of TechnologyBeijing 100081China IFN-CNR Piazza Leonardo da Vinci 3220133 MilanoItaly National High Magnetic Field Laboratory Los Alamos National LaboratoryLos AlamosNew Mexico 87545USA

Ternary I-III-VI2 nanocrystals(NCs),such as AgInS_(2) and CuInS_(2),are garnering interest as heavy-metal-free materials for photovoltaics,luminescent solar concentrators,LEDs,and bioimaging.The origin of the emission and absorption properties in this class of NCs is still a subject of debate.Recent theoretical and experimental studies revealed that the characteristic Stokesshifted and long-lived luminescence of stoichiometric CuInS_(2) NCs arises from the detailed structure of the valence band featuring two sublevels with different parity.The same valence band substructure is predicted to occur in AgInS_(2) NCs,yet no experimental confirmation is available to date.Here,we use complementary spectroscopic,spectro-electrochemical,and magneto-optical investigations as a function of temperature to investigate the band structure and the excitonic recombination mechanisms in stoichiometric AgInS_(2) NCs.Transient transmission measurements reveal the signatures of two subbands with opposite parity,and photoluminescence studies at cryogenic temperatures evidence a dark state emission due to enhanced exchange interaction,consistent with the behavior of stoichiometric CuInS_(2) NCs.Lowering the temperature as well as applying reducing electrochemical potentials further suppress electron trapping,which represents the main nonradiative channel for exciton decay,leading to nearly 100%emission efficiency.

关键词： parity valence applying

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