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Acta Geochimica 2021年第6期40卷 1023-1049页

作者： Bruna Saar de Almeida Mauro César Geraldes Carlos Augusto Sommer Felipe Corrales Antonio Joāo Paes de barros Universidade do Estado do Rio de Janeiro Rio de JaneiroBrazil University of Geneva GenevaSwitzerland Universidade Federal do Rio Grande do Sul Rio Grande do SulBrazil METAMAT(Mato Grosso State Geological Survey) CuiabaBrazil

The volcanic rocks of the Colíder and Roosevelt formations are extensively exposed in the south-central portion of the Amazonian Craton where effusive and pyroclastic rocks have been *** units,topped by chemical sediments and oceanic facies as rhyolite and andesite lavas,rhyodacite,and porphyritic dacite,with frequent intercalations of pyroclastic and epiclastic ***-rock geochemistry for 55 samples of rhyolitic to andesitic composition suggests the involvement of fertile mantle-derived components with E-MORB to OIB *** analyzed rocks display calc-alkaline to shoshonitic affinity consistent with generation related to an active continental *** whole-rock Sm-Nd isotope data from selected felsic volcanic rocks of the Colíder and Roosevelt formations yield negative initial eNd values between–3 and–9,indicating the predominantly crustal nature of the parental magmas with early Archean to late Paleoproterozoic(ca.2.5–2.0 Ga)depleted mantle model ages.

关键词： Amazonian craton Geochemistry Sm-Nd isotopes Paleoproterozoic Volcanism

Y-chromosome microdeletions in nonobstructive azoospermia and severe oligozoospermia

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Asian Journal of Andrology 2017年第3期19卷 338-345页

作者： Carolina Goncalves Mariana Cunha Eduardo Rocha Susana Fernandess, Joaquina Silva Luis Ferraz Cristiano Oliveira Alberto barros Mairio Sousa Department of Biology ClCECO University of Aveiro Campus Universitario de Santiago 3810-193 Aveiro Portugal Department of Microscopy Laboratory of Cell Biology Institute of Biomedical Sciences Abel Salazar University of Porto (ICBAS-UP) Rua Jorge Viterbo Ferreira 228 4050-313 Porto Portugal and Multidisciplinary Unit for Biomedical Research ICBAS-UP Portugal Centre for Reproductive Genetics Prof. Alberto barros Av. do Bessa 240 1° Dto. Frente 4100-009 Porto Portugal Department of Microscopy Laboratory of Histology and Embryology ICBAS-UP Rua Jorge Viterbo Ferreira 228 4050-313 Porto Portugal Department of Genetics Faculty of Medicine University of Porto Alameda Prof. Hernani Monteiro 4200-319 Porto Portugal and Institute for Innovation and Health Research (13S) University of Porto Portugal Department of Urology Hospital Center of Vila Nova de Gala Rua Conceicao Fernandes 4430-502 Vila Nova de Gala Portugal.

The aim of the present work was to present the outcomes of the patients with Y-chromosome microdeletions treated by intracytoplasmic sperm injection （ICSI）, either using fresh （TESE） or frozen-thawed （TESE-C） testicular sperm and ejaculated sperm （EJAC）. The originality of this work resides in the comparisons between the different types of Y-microdeletions （AZFa, AZFb, and AZFc） and treatments, with detailed demographic, stimulation, embryological, clinical, and newborn （NB） outcomes. Of 125 patients with Y-microdeletions, 33 patients presented severe oligozoospermia （18 performed ICSI with ejaculated sperm） and 92 secretory azoospermia （65 went for TESE with 40 having successful sperm retrieval and performed ICSI）. There were 51 TESE treatment cycles and 43 TESE-C treatment cycles, with a birth of 19 NB （2 in AZFa/TESE-C, 12 in AZFc/TESE, and 5 in AZFc/TESE-C）. Of the 29 EJAC cycles, there was a birth of 8 NB （in AZFc）. In TESE and EJAC cycles, there were no significant differences in embryological and clinical parameters. In TESE-C cycles, there was a significant lower oocyte maturity rate, embryo cleavage rate and mean number of embryos transferred in AZFb, and a higher mean number of oocytes and lower fertilization rate in AZFc. In conclusion, although patients with AZFc microdeletions presented a high testicular sperm recovery rate and acceptable clinical outcomes, cases with AZFa and AZFb microdeletions presented a poor prognosis. Due to the reported heredity of microdeletions, patients should be informed about the infertile consequences on NB and the possibility of using preimplantation genetic diagnosis for female sex selection.

关键词： intracytoplasmic sperm injection newborn outcomes nonobstructive azoospermia severe oligozoospermia testicularsperm extraction Y-chromosome microdeletions

Late onset acute Vogt-Koyanagi-Harada syndromechallenges on the way

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International Journal of Ophthalmology(English edition) 2018年第3期11卷 524-527页

作者： Sandra Rodrigues-barros Jacqueline Martins Sousa Bruno Carvalho Gabriel Andrade Heloisa Nascimento Department of Ophthalmology Hospital Garcia de Orta Avenida Torrado da Silva Almada 2801-951 Portugal Department of Ophthalmology and Visual Sciences Escola Paulista de Medicina Universidade Federal de Sao Paulo Rua Botucatu 821 Vila Clementino Sao Paulo SP 04023-062 Brazil Department of Ophthalmology Centro Hospitalar de Lisboa Central Alameda Santo Antonio dos Capuchos Lisboa 1169- 050 Portugal

Dear Editor,We would like to share some clinical cases of late onset acute Vogt-Koyanagi-Harada syndrome （VKH）, a rare diagnosis in this age range.

关键词： Late onset acute Vogt-Koyanagi-Harada syndromechallenges the way

Doxycycline induces bone repair and changes in Wnt signalling

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International Journal of Oral Science 2017年第3期9卷 158-166页

作者： kátia do nascimento gomes ana paula negreiros nunes alves paula góes pinheiro dutra glauce socorro de barros viana faculty of dentistry pharmacy and nursingfederal university of cearáFortalezaBrazil faculty of medicine federal university of cearáFortaleza Brazil

Doxycycline （DOX） exhibits anti-inflammatory and MMP inhibitory properties. The objectives of this study were to evaluate the effects of DOX on alveolar bone repair. Controls （CTL） and DOX-treated （10 and 25 mg. kg- 1） molars were extracted, and rats were killed 7 or 14 days later. The maxillae were processed and subjected to histological and immunohistochemical assays. Hematoxylin-eosin staining （7th day） revealed inflammation in the CTL group that was partly reversed after DOX treatment. On the 14th day, the CTL group exhibited bone neoformation, conjunctive tissue, re-epithelization and the absence of inflammatory infiltrate. DOX-treated groups exhibited complete re-epithelization, tissue remodelling and almost no inflammation. Picrosirius red staining in the DOXlO group （7th and 14th days） revealed an increased percentage of type I and III collagen fibres compared with the CTL and DOX25 groups. The DOXlO and DOX25 groups exhibited increases in osteoblasts on the 7th and 14th days. However, there were fewer osteoclasts in the DOXlO and DOX25 groups on the 7th and 14th days. Wnt-lOb- immunopositive cells increased by 130% and 150% on the 7th and 14th days, respectively, in DOX-treated groups compared with the CTL group. On the 7th day, Dickkopf （Dkk）-I immunostaining was decreased by 63% and 46% in the DOXlO and DOX25 groups, respectively. On the 14th day, 69% and 42% decreases in immunopositive cells were observed in the DOXlO and DOX25 groups, respectively, compared with the CTL group. By increasing osteoblasts, decreasing osteoclasts, activating Wnt lOb and neutralising Dkk, DOX is a potential candidate for bone repair in periodontal diseases.

关键词： alveolar bone loss bone diseases bone repair doxycycline Dickkopf-1 immunohistochemistry Wnt-lOb

Preandean geological confguration of the eastern North Patagonian Massif, Argentina

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Geoscience Frontiers 2013年第6期4卷 693-708页

作者： Daniel A.Gregori José Kostadinoff Guillermina Alvarez Ariel Raniolo Leonardo Strazzere Juan C.Martínez Mercedes barros INGEOSUR Cátedra de Geología ArgentinaUniversidad Nacional del SurSan Juan 6708000 Bahía BlancaArgentina Departamento de Física Universidad Nacional del SurArgentina Cátedra de Geofísica Universidad Nacional del SurArgentina Cátedra de Cartografía Universidad Nacional del SurArgentina INGEOSUR Cátedra de PetrologíaUniversidad Nacional del SurArgentina

The Preandean geological configuration of the eastern North Patagonian Massif is established through the use of geological and geophysical *** positive gravity anomalies located near the Atlantic coast are due to 535 and 540 Ma old rocks belonging to the Pampean Orogeny （Precambrian-middle Cambrian）,which are widely recognized in central and northern *** Famatinian Cycle （Ordovician-Devonian） is represented by a Silurian-Devonian marine basin equivalent to those of eastern-central Argentina and South Africa,and which was deformed at the end of the Devonian byan～E-W to WNW-ESE compressional event,part of the Famatinian *** strong gravity gradients,the NW-SE belt is coincident with fault zones which were originated during the Gondwanide *** event also produced NW-SE overthrusting of the Silurian-Devonian sequences and strike-slip faults that displaced blocks in the same *** deformation event belongs to the Gondwanide Orogeny that includes movements related to a counterclockwise rotation of blocks in northern *** strong negative anomalies located in the western part of the area stem from the presence of rocks of the Jurassic Ca（n）adón Asfalto basin interbedded in the Marifil *** volcaniclastic sequences show mild deformation of accommodation zones in a pre-Jurassic paleorelief.

关键词： Preandean geological configuration North Patagonia Argentina Tectonics

Short mucin 1 alleles are associated with low virulent H pylori strains infection

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World Journal of Gastroenterology 2007年第12期13卷 1885-1886页

作者： Bárbara Peleteiro Nuno Lunet Filipe Santos-Silva Leonor David Céu Figueiredo Henrique barros Department of Hygiene and Epidemiology Medical Faculty University of Porto Portugal Institute of Molecular Pathology and Immunology of the University of Porto Portugal

TO THE EDITORWe read with interest the article published by Nguyen et al in the World Journal of Gastroenterology, showing an association between short MUC6 alleles and H pjloff infection. These results, together with previous observations by Vinall et al, reinforce the role of mucin genes （MUC6 and MUC1） VNTR polymorphisms for the variability in individual susceptibility to H pylori infection that cannot be explained by differences in environmental factors.

关键词： H pylori MUC1 Polymorphism cagA vacA

To Open the Mouth,to Show the Tongue:Anthropophagic Gestures in Brazilian Art

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Journal of Foreign Languages and Cultures 2021年第2期5卷 143-151,155,156页

作者： Eduardo Jorge de Oliveira andre Masseno University of Zurich

This essay seeks to articulate a detailed reading through two anatomical selections-the mouth and tongue-in Brazilian art from the end of the *** reading is part of a shift in the matrix of Oswald de Andrade’s“Anthropophagic Manifesto,”originally published in the Re vista de Antropofagia in 1928,whose interpretations spread in Brazil during the second half of the 20th *** study mobilises elements of the manifesto and its resonance in the works of artists such as Anna Maria Maiolino,Lygia Pape,Paulo Bruscky,and Lenora de barros.

关键词： mouth tongue Anthropophagic Manifesto Oswald de Andrade Brazilian art

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可变信息板安全信息有效性研究(英文)

交通运输系统工程与信息 2010年第3期10卷 18-23页

作者： TAY Richard DE barros Alex 拉筹伯大学法律及管理系澳大利亚维多利亚州墨尔本市卡尔加里大学土木工程系加拿大阿尔伯特省卡尔加里市T2N1N4

虽然多数先进技术应用的目的是改善路网的运行效率和安全性,但目前为止其在提高道路安全性方面的作用并不突出.例如,可以提供大容量、多方面信息的可变信息板,其设立之初的唯一目的是引导驾驶员的道路行驶.事实上,这种信息传达装置在不... 详细信息

虽然多数先进技术应用的目的是改善路网的运行效率和安全性,但目前为止其在提高道路安全性方面的作用并不突出.例如,可以提供大容量、多方面信息的可变信息板,其设立之初的唯一目的是引导驾驶员的道路行驶.事实上,这种信息传达装置在不发布路段行驶信息的情况下,还可以发布交通安全信息以改善交通安全状况.本文选取两种禁止超速信息为研究对象,分析了该信息的发布对于驾驶员态度和路段行驶车速的影响.对近100名驾驶员进行抽样调查.测试路段为加拿大埃德蒙顿市和卡尔加里市间2号高速公路.研究结果表明,本文所选取的两种禁止超速标识对驾驶员态度和行驶车速产生的影响相对较小.

关键词：交通工程信息技术可变信息板加速道路安全信息驾驶行为

Mechanism of friction reduction of unsaturated fatty acids as additives in diesel fuels

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Friction 2013年第3期1卷 252-258页

作者： Jean Michel MARTIN Christine MATTA Maria-Isabel De barros BOUCHET Cyrielle FOREST Thierry Le MOGNE Thomas DUBOIS Michael MAZARIN Laboratory of Tribology and System Dynamics Ecole Centrale de Lyon69134 EcullyFrance TOTAL CReSBP2269360 Solaize CedexFrance

This paper investigates the effect of unsaturated fatty acid additives on the lubricating properties of a biodiesel,composed of a blend of fatty acid methyl esters(FAMEs)and a conventional diesel *** presence of fatty acids as additives for biodiesel improves their lubricating properties at elevated temperature *** formation of a protective lubricating tribochemical film on the steel contact surfaces has been *** temperature conditions and possibly oxygen are needed to form this film that reduces friction and limits *** analytical tools have revealed the insulating nature of the formed tribofilm and its chemical ***-induced reticulation is thought to play a major role in the growth of this insulating film.

关键词： biodiesel low friction fatty acids tribochemistry surface analysis

Mitochondrial Translation in Health and Disease

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Open Journal of Endocrine and Metabolic Diseases 2013年第2期3卷 1-9页

作者： Claudia C. Ferreiro-barros Mario H. barros Departamento de Microbiologia—Instituto de Ciencias Biomedicas—Universidade de Sao Paulo Sao Paulo Brazil

Mitochondrial disorders have become the most common cause of inborn errors of metabolism. Impairments in mitochondrial protein synthesis are one of the causes of these diseases, which are clinically and genetically heterogeneous. The mitochondrial translation machinery decodes 13 polypeptides essential for the oxidative phosphorylation process. Mitochondria protein synthesis depends on the integrity of mitochondrial rRNAs and tRNAs genes, and at least one hundred of nuclear encoded products. Diseases caused by mutations in mitochondrial genes as well as in ribosomal proteins, translational factors, RNA modifying enzymes, and all other constituents of the translational machinery have been described in patients with combine respiratory chain deficiency, and are the object of this review.

关键词： Mitochondrial Diseases Respiratory Chain