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Clinical Application of Dynamic Gait index-Brazilian Brief version

Advances in Aging Research 2018年第6期7卷 113-118页

作者： Carlos Kazuo Taguchi élida Pinto Costa Lucas vieira Alves Larissa Karoline Santos Erbson Rodrigues de Oliveira Silva Brenda Carla de Lima Araújo Fabíola andréa andrade dos Santos Allan Robert da Silva Audiology Departament Federal University of Sergipe S&atilde o Cristóv&atilde o Brazil Federal University of Sergipe S&atilde o Cristóv&atilde o Brazil Education Coordinator of Sergipe State Aracaju Brazil Speech Therapist and Audiology Departament Federal University of Sergipe S&atilde o Cristóv&atilde o Brazil University Hospital Board Federal University of Sergipe S&atilde o Cristóv&atilde o Brazil Statistical Departament Federal University of Sergipe S&atilde o Cristóv&atilde o Brazil

introduction: in elderly, the progressive degenerations in the nervous system and vestibular system compromise the human body balance leading to a greater risk of falls. The Dynamic Gait index is a protocol that predicts risks to falls in seniors. Objective: To analyze the results of the application of the Dynamic Gait index (DGi)-Brazilian brief proposal and establish correlation with the original version. Methods: Study approved by the Ethics and Research Committee of Federal University of Sergipe (number 0197.0.107000.09). We analyzed 223 files of socially active elderly, female gender, aged ranged 60 to 85 years, mean 68.54 (±7.61) years since 2014. The volunteers were evaluated by the DGi-Brazil. For the statistical analysis, the Pearson Correlation Momentum Correlation Test with Spearman Correlation was used, with p ≤ 0.05 and r = 1.0. Results: Sixty-three (27.8%) of the volunteers presented an altered DGi scores. The statistical analysis indicated that Task 1 and Task 2 did not contribute to decrease the total score in the test. The worst performances occurred in Tasks 3, 5 and 6. There was founded a positive correlation between Tasks 1 and 2;1 and 8;3 and 4;3 and 5;4 and 5;2 and 4;2 and 7. Negative correlation occurred between Tasks 4 and 8, and 6 was not correlated with another Task. Conclusion: The DGi-Brazilian brief version presented an excellent correlation with the original proposal and may be useful in clinical practice as a tool to evidence future risks of falls in the elderly people.

关键词： Aged Postural Balance Accidental Falls Clinical Protocols

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Efficacy and tolerability of hydrogen carbonate-rich waterfor heartburn

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World Journal of Gastrointestinal Pathophysiology 2016年第1期7卷 171-180页

作者： andré-michael beer ralf uebelhack ute pohl Klinik Blankenstein Ruhr-Universität Bochum45527 HattingenGermany Analyze and Realize GmbH 13456 BerlinGermany

AiM To investigate the efficacy and safety of mineralwater with a high content of hydrogen carbonate inpatients with ***： This open, single-center, single-armclinical pilot study enrolled 50 patients, 18-64 yearsold, who had been suffering from heartburn at leasttwice a week for at least 3 mo before entering thestudy. Pharmacological treatment of heartburn was notpermitted, and patients with severe organic diseaseswere excluded. After a run-in period of one week, theparticipants received 1.5 L of the test water for thefollowing 6 wk; 300 mL with meals t.i.d., the remainderto be drunk throughout the day. During the trial, therewere five visits at the study center （screening, baseline,two interim visits and the final visit）. The efficacyendpoints included incidence and duration of heartburnepisodes per week by patient＇s self-assessment （heartburndiary） as well as changes in symptom severity asper symptom specific questionnaires [Reflux Disease Questionnaire （RDQ）; Quality of Life in Reflux andDyspepsia （QOLRAD）; Gastrointestinal Quality of Lifeindex] and overall health-related quality of life per SF-12（12-question short form） at each visit. At the end of thestudy, patients and investigators independently ratedthe overall efficacy of the test water on a 4-point Likertscale. Safety was assessed by evaluation of adverseevents （AEs）, vital signs （heart rate, blood pressure）and laboratory parameters. Changes from initial to finalexaminations were assessed by the non-parametricWilcoxon test; categorical variables were comparedusing the χ 2 test, and for more than 5 categories, by ***： Twenty-eight participants were men, 22women. The mean age of the patients in the fullanalysis set/intention-to treat population （FAS/iTT） was40.6 years. Forty-two participants completed the studyaccording to the study protocol and formed the perprotocolset （PP population）; 48 participants drank thewater at least once as requested and were analyzedas iTT population.

关键词： Heartburn Hydrogen carbonate-rich mineralwater Open clinical pilot study Patients Regurgitation Gastroesophageal reflux disease symptoms Dyspepsia Blood pressure Tolerability Quality of life

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耦合膜系统实现从工业污水和卤水中有价物质提取

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膜科学与技术 2019年第4期39卷 148-148页

作者：何涛 Alexey volkov andréa Moura Bernardes Lue-Ann de Kock Sourja Ghosh 膜材料与分离技术实验室中国科学院上海高等研究院上海201210 A.v.Topchiev institute of Petrochemical Synthesis Russian Academy of SciencesLeninsky pr.29MoscowRussia119991 Federal University of Rio Grande do Sul LACOR-DEMAT-PPGE3M-UFRGSAv.Bento Gon alves 9500Porto Alegre.RSBrasil University of South Africa Nanotechnology and Water Sustainability Research Unit(NanoWS)South Africa Water Technology Division CSIR-CGCRIKolkataIndia

金砖五国,包括中国、俄罗斯、巴西、南非和印度,为世界经济高速发展的新兴经济体.在人口增长、环境保护、饮用水以及食品需求等方面存在共同问题.金砖五国社会发展分布呈现两极化,有人口高密度发达工业和农业地区,也有基础设施、电力和... 详细信息

金砖五国,包括中国、俄罗斯、巴西、南非和印度,为世界经济高速发展的新兴经济体.在人口增长、环境保护、饮用水以及食品需求等方面存在共同问题.金砖五国社会发展分布呈现两极化,有人口高密度发达工业和农业地区,也有基础设施、电力和净水供应严重缺乏的偏远地区.我们面临与西方发达国家不同的挑战.生物工艺技术可能会有效地解决碳循环问题,化石燃料会逐渐被可再生能源替代,但是对于制约高科技和经济发展的稀有和贵重金属,一旦被开采并进入到生态圈,则很难再生且不可持续.最为典型的是电子器件、电池和太阳能电池板等的需求增长,大量的贵金属从地下资源流失到城市和工业生产过程.将这些资源重新回收是熵减小过程,需要耗费大量能源.

关键词：金砖五国新兴经济体太阳能电池板两极化食品需求生物工艺贵重金属基础设施

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Non invasive blood flow measurement in cerebellum detects minimal hepatic encephalopathy earlier than psychometric tests

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World Journal of Gastroenterology 2014年第33期20卷 11815-11825页

作者： vicente Felipo Amparo Urios Carla Giménez-Garzó Omar Cauli Maria-Jesús andrés-Costa Olga González Miguel A Serra Javier Sánchez-González Roberto Aliaga Remedios Giner-Durán vicente Belloch Carmina Montoliu Laboratory of Neurobiology Centro Investigación Príncipe Felipe 46012Valencia Spain Fundación investigación Hospital Clínico de valencia. instituto de investigación Sanitaria INCLIVA 46010 Valencia Spain Servicio DigestivoHospital Arnau de vilanova 46015 Valencia Spain Grupo Hepatología Servicio Aparato Digestivo Hospital Clínico de Valencia 46010 Valencia Spain Philips Healthcare Iberia 28050 Madrid Spain ERESA Unidad RM 46015 Valencia Spain Departamento de Patología Facultad de Medicina Universidad de Valencia 46010 Valencia Spain

AiM: To assess whether non invasive blood flow measurement by arterial spin labeling in several brain regions detects minimal hepatic encephalopathy. METHODS: Blood flow(BF) was analyzed by arterial spin labeling(ASL) in different brain areas of 14 controls, 24 cirrhotic patients without and 16 cirrhotic patients with minimal hepatic encephalopathy(MHE). images were collected using a 3 Tesla MR scanner(Achieva 3T-TX, Philips, Netherlands). Pulsed ASL was performed. Patients showing MHE were detected using the battery Psychometric Hepatic Encephalopathy Score(PHES) consisting of five tests. Different cognitive and motor functions were also assessed: alterations in selective attention were evaluated using the Stroop test. Patients and controls also performed visuo-motor and bimanual coordination tests. Several biochemical parameters were measured: serum pro-inflammatory interleukins(iL-6 and iL-18), 3-nitrotyrosine, cGMP and nitrates+nitrites in plasma, and blood ammonia. Bivariate correlations were ***: in patients with MHE, BF was increased in cerebellar hemisphere(P = 0.03) and vermis(P = 0.012) and reduced in occipital lobe(P = 0.017). BF in cerebellar hemisphere was also increased in patients without MHE(P = 0.02). Bimanual coordination was impaired in patients without MHE(P = 0.05) and much more in patients with MHE(P visuo-motor coordination was impaired only in patients with MHE(P ion was slightly affected in patients without MHE and more strongly in patients with MHE(Pin cerebellar hemisphere and vermis correlated with performance in most tests of PHES [(number connection tests A(NCT-A), B(NCT-B)and line tracing test] and in the congruent task of Stroop test. BF in frontal lobe correlated with NCT-A. Performance in bimanual and visuomotor coordination tests correlated only with BF in cerebellar hemisphere. BF in occipital lobe correlates with performance in the PHES battery and with CFF. BF in cerebellar

关键词： Arterial spin labelling Neurological impair-ment B

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vibration Analysis and Fatigue Assessment of *** ii:Mechanical Equipment

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Journal of Civil Engineering and Architecture 2021年第10期15卷 504-510页

作者： Ana C.S.da Silva Gabriel M.Sant’Anna Lucia H.G.Cardoso andrév.Castilho JoséG.S.da Silva State University of Rio de Janeiro(UERJ) Rio de Janeiro/RJ 20550-900Brazil Structural Engineering Department(ESTR) State University of Rio de Janeiro(UERJ)Rio de Janeiro/RJ 20550-900Brazil

Floors subjected to mechanical equipment loads frequently present problems associated with excessive vibration which can cause human discomfort or even reduce the structure service *** this context,this work aims to develop an analysis methodology in order to assess the fatigue performance of steel-concrete composite floors,when subjected to vibrations induced by mechanical *** studied structural model corresponds to a steel-concrete composite floor spanning 10 m by 10 m,with a total area of 100 m^(2).The numerical model developed for the dynamic analysis adopted the usual mesh refinement techniques present in finite element method(FEM)simulations implemented in the ANSYS *** investigated floor dynamic response was calculated through the consideration of the dynamic loadings imposed by the mechanical equipment,simulated based on the use of harmonic forces applied on the concrete ***,the dynamic structural response was performed considering several scenarios for the positioning of the equipment,in order to verify the occurrence of excessive *** fatigue assessment is based on a linear cumulative damage rule through the use of the Rainflow-counting algorithm and S-N curves from traditional design *** results of this investigation indicated that the equipment position affects directly the floor dynamic structural response and also significantly influences the structure service life.

关键词： Steel-concrete composite floors mechanical equipment dynamic structural analysis fatigue assessment.

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Diversity among isolates of the Tangerine Pathotype of Alternaria alternata

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American Journal of Plant Sciences 2018年第2期9卷 196-215页

作者： andréa Celina Ferreira Demartelaere Luciana Cordeiro do Nascimento Cristina O.Marinho Marciano Costa Nunes Patrícia Clemente Abraao Rommel S.S.Gomes Monica Danielly de Mello Oliveira Larissa Almeida Mirelly M.Porcino Caroline vargas e Silva Wilza C.O.Souza Programa de Pós-Graduacao em Agronomia Departamento de Fitotecnia e Ciencias AmbientaisUniversidade Federal da ParaíbaAreiaBrazil

The tangerine pathotype of Alternaria alternata is the aetiological agent of Alternaria brown spot on tangerines. in the state of Paraíba, Brazil, its occurrence on “Dancy” tangerine trees is associated with genetic aspects as well as the influence of environmental conditions on reproduction and dissemination within and between populations. The aim of the present study was to evaluate the diversity of isolates of this pathogen using morphophysiological and molecular markers. For the analysis of mycelial growth and sporulation, 30 isolates from different locations were examined at 24-hour intervals until the seventh day, when the spores were quantified. The 30 isolates were characterised based on molecular markers (iSSR) and genetic similarity (Jaccard index). A factor arrangement was used: 30 isolates, four media (ODA, PDA, LEA and v8), three light regimes (continuous dark, alternating light and continuous light) and three temperatures (15°C, 25°C and 35°C), with 12 repetitions. Groups 1, 2 and 3 presented low genetic variability. Group 4 showed high genetic variability of the isolates obtained from the Massaranduba (state of Paraíba-Brazil) producing region and higher mycelial growth and sporulation of A. alternata. The continuous light regime and the temperature 25°C in PDA and v8 media were the ideal conditions for the mycelial growth and sporulation, respectively, of the isolates of A. alternata.

关键词： Citrus tangerine Alternaria Brown Spot Fungal variability Environment Factors iSSR Markers

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Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease(GCKD)cohort

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Bone Research 2023年第4期11卷 764-771页

作者： Katharina Charlotte Reimer Jennifer Nadal Heike Meiselbach Matthias Schmid Ulla T.Schultheiss Fruzsina Kotsis Helena Stockmann Nele Friedrich Matthias Nauck vera Krane Kai-Uwe Eckardt Markus P.Schneider Rafael Kramann Jürgen Floege Turgay Saritas Department of Nephrology Rheumatologyand Clinical ImmunologyUniversity Hospital RWTH AachenAachenGermany institute of Experimental Medicine and Systems Biology RWTH Aachen UniversityAachenGermany institute for Cell and Tumor Biology RWTH Aachen UniversityAachenGermany institute of Medical Biometry Informatics and EpidemiologyUniversity Hospital of BonnBonnGermany Department of Nephrology and Hypertension University of Erlangen-NürnbergErlangenGermany institute of Genetic Epidemiology Faculty of Medicine and Medical Center-University of FreiburgFreiburgGermany Department of Medicine iv-Nephrology and Primary Care Faculty of Medicine and Medical Center-University of FreiburgFreiburgGermany Department of Nephrology and Medical intensive Care Charité-Universitätsmedizin BerlinBerlinGermany Department of Nephrology University Medical Center RegensburgRegensburgGermany institute of Clinical Chemistry and Laboratory Medicine University Medicine GreifswaldGreifswaldGermany DZHK(German Centre for Cardiovascular Research) Partner Site GreifswaldUniversity MedicineGreifswaldGermany Department of Medicine i Division of NephrologyUniversity Hospital WürzburgWürzburgGermany

Mineral and bone disorder(MBD)in chronic kidney disease(CKD)is tightly linked to cardiovascular disease(CvD).in this study,we aimed to compare the prognostic value of nine MBD biomarkers to determine those associated best with adverse cardiovascular(Cv)outcomes and *** 5217 participants of the German CKD(GCKD)study enrolled with an estimated glomerular filtration rate(eG FR)between 30–60 mL·min-1 per 1.73 m2 or overt proteinuria,serum osteoprotegerin(OPG),C-terminal fibroblast growth factor-23(FGF23),intact parathyroid hormone(iP TH),bone alkaline phosphatase(BAP),cross-linked C-telopeptide of type 1 collagen(CTX1),procollagen 1intact N-terminal propeptide(P1NP),phosphate,calcium,and 25-OH vitamin D were measured at *** with missing values among these parameters(n=971)were excluded,leaving a total of 4246 participants for *** a median follow-up of6.5 years,387 non-Cv deaths,173 Cv deaths,645 nonfatal major adverse Cv events(MACEs)and 368 hospitalizations for congestive heart failure(CHF)were *** and FGF23 were associated with all outcomes,with the highest hazard ratios(HRs)for *** the final Cox regression model,adjusted for Cv risk factors,including kidney function and all other investigated biomarkers,each standard deviation increase in OPG was associated with non-Cv death(HR 1.76,95%Ci:1.35–2.30),Cv death(HR 2.18,95%Ci:1.50–3.16),MACE(HR 1.38,95%Ci:1.12–1.71)and hospitalization for CHF(HR 2.05,95%Ci:1.56–2.69).Out of the nine biomarkers examined,stratification based on serum OPG best identified the CKD patients who were at the highest risk for any adverse Cv outcome and mortality.

关键词： Kidney cardiovascular vitamin

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2例日光性视网膜病变患者的多焦视网膜电图和光学相干断层扫描表现

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世界核心医学期刊文摘（眼科学分册） 2005年第2期1卷 11-11页

作者： Schatz P. Eriksson U. Ponjavic v. andr éasson S. 秦雪娇 Department of Op hthalmology Lund University Hospital 221 85 Lund Sweden

Purpose: Clinical investigation of central retinal dysfunction in two cases of solar retinopathy. Methods: Two patients were examined for best corrected visua l acuity (vA), fundus inspection, visual fields, multifocal electroretinography (mfERG) with a stimulus pattern of 241 hexagons and, at follow-up, also with op tical coherence tomography (OCT). Results: At the initial examination, mfERG rev ealed central retinal dysfunction, which had improved by the time of follow-up. in Case 1, a foveal oedema regressed over time, although vA remained slightly r educed. in Case 2, OCT showed spots of increased reflectivity corresponding to t he patient’s symptoms. Conclusion: Central retinal dysfunction due to solar ret inopathy may improve over time. However, structural and functional changes may p ersist. This report illustrates that mfERG and OCT are useful tools for objectiv e documentation of the pathology in solar retinopathy.

关键词：视网膜电图视网膜病变视网膜功能黄斑中心凹光性刺激模式矫正视力监测工具六角形临床症状

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Adsorption of 5.5’-Disulfonicindigotin(5.5’-Di)onto Green Coconut Fiber(Cocos nucifera L.):Kinetic and isotherms

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Journal of Encapsulation and Adsorption Sciences 2014年第2期4卷 37-52页

作者： Lívia F.Zeferino ivanise Gaubeur Maria E.v.Suárez-iha Patricia A.M.Freitas Centro Universitário do instituto Mauáde Tecnologia Escola de Engenharia MauáSao Caetano do SulBrazil Centro de Ciências Naturais e Humanas Universidade Federal do ABCSanto AndréBrazil Escola de Engenharia Universidade Presbiteriana MackenzieSao PauloBrazil

Green coconut fiber (Cocos nucifera L.) has been largely used in solid-phase extraction. The effect of the initial dye concentration (1.91, 3.02 and 4.02) × 10-5 mol·L-1 and solid phase contact (SPE) time were evaluated at different temperatures (283, 298 and 313) K at pH 2. Kinetic experimental data were applied to three simplified kinetic models: pseudo-first order, pseudo-second order, and intraparticle diffusion. The adsorption of 5.5’-Di onto the solid phase showed excellent fit to the pseudo-second order model. At 283, 298 and 313 K the maximum sorption, qmax,exp, for the lowest initial concentration (Co = 1.91 × 10-5 mol·L-1) of 5.5’-Di were (5.01, 5.24 and 6.14) × 10-4 g·g-1;for Co = 3.02 × 10-5 mol·L-1 (0.93, 1.01 and 1.03) × 10-3

关键词： 5.5’-Disulfonicindigotin Green Coconut isotherm and Kinetic Modeling

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2015年巴西寨卡病毒感染与小头畸形之间可能存在的关联

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上海预防医学 2017年第1期29卷 82-84页

作者： Lavinia Schuler-Faccini Erlane M.Ribeiro ian M.L.Feitosa Dafne D.G.Horovitz Denise P.Cavalcanti andréPessoa Maria Juliana R.Doriqui Joao ivanildo Neri Joao Monteiro de Pina Neto Hector Y.C.Wanderley Mirlene Cernach Antonette S.El-Husny Marcos v.S.Pone Cassio L.C.Serao Maria Teresa v.Sanseverino 朱秋丽(译) 陆仁敏(校) Universidade Federal do Rio Grande do Sul Brazil Hospital infantil Albert Sabin FortalezaCEBrazil Universidade Federal de Pernambuco Brazil Fundaqao Oswaldo Cruz Rio de JaneiroBrazil University of Campinas Sao PauloBrazil Hospital infantil Juvencio Mattos MaranhaoBrazil Universidade Potiguar Rio Grande do NorteBrazil University of Sao Paulo Ribeirao PretoBrazil Secretaria de Estado da Saude do Espirito Santo Brazil Universidade Federal de Sao Paulo Brazil Centro Universitario do Estado do Para Brazil Universidade do Estado do Rio de Janeiro Brazil Hospital de Clinicas de Porto Alegre Brazil Brazilian Medical Genetics Society-Zika Embryopathy Task Force 不详

2015年初,通过伊蚊传播的寨卡病毒在登革热病毒流行地区巴西的东北部暴发,该病毒属于黄病毒属。2015年9月,寨卡病毒流行地区开始出现关于小头畸形患儿的报道,且报道数量呈现增加的趋势。与此同时,有2名妇女产前超声检查发现有胎儿畸形,... 详细信息

2015年初,通过伊蚊传播的寨卡病毒在登革热病毒流行地区巴西的东北部暴发,该病毒属于黄病毒属。2015年9月,寨卡病毒流行地区开始出现关于小头畸形患儿的报道,且报道数量呈现增加的趋势。与此同时,有2名妇女产前超声检查发现有胎儿畸形,在她们的羊水中也检测出寨卡病毒RNA。

关键词：小头畸形病毒感染报道数量登革热病毒产前超声检查胎儿畸形西寨黄病毒属病毒流行先天性异常

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