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Science China(Life Sciences) 2019年第4期62卷 526-534页

作者： Vandeclécio Lira da Silva andré mauricio ribeiro dos santos Wilfredo Blanco Sandro José de Souza Bioinformatics Multidisciplinary Environment (BioME) Universidade Federal do Rio Grande do Norte (UFRN) Programa de Pós-Gradua??o em Genética e Biologia Molecular (PPGBM) Universidade Federal do Pará (UFPA) Department of Computer Science Universidade Estadual do Rio Grande do Norte (UERN) Brain Institute Universidade Federal do Rio Grande do Norte (UFRN)

The gain of transcription factor binding sites(TFBS) is believed to represent one of the major causes of biological *** we used strategies based on comparative genomics to identify 21,822 TFBS specific to the human lineage(TFBS-HS),when compared to chimpanzee and gorilla genomes. More than 40%(9,206) of these TFBS-HS are in the vicinity of 1,283 genes.A comparison of the expression pattern of these genes and the corresponding orthologs in chimpanzee and gorilla identified genes differentially expressed in human tissues. These genes show a more divergent expression pattern in the human testis and brain, suggesting a role for positive selection in the fixation of TFBS gains. Genes associated with TFBS-HS were enriched in gene ontology categories related to transcriptional regulation, signaling, differentiation/development and nervous ***, genes associated with TFBS-HS present a higher expression breadth when compared to genes in general. This biased distribution is due to a preferential gain of TFBS in genes with higher expression breadth rather than a shift in the expression pattern after the gain of TFBS.

关键词： TFBS transcript factor human evolution expression breadth

Elevation transition of aquatic insects closely matches a thermal feature in the Yungas of Northwestern Argentina

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Journal of Mountain Science 2024年第2期21卷 433-448页

作者： Alexandra BUITRAGO-GUACANAME Carlos MOLINERI andrés LIRA-NORIEGA Daniel andrés dos santos Neotropical Biodiversity Institute(CONICET-UNT) UNT-DomesHorco Molle S/N4107 TucumánArgentina CONACYT Research Fellow Network of Advanced Molecular StudiesInstitute of Ecology A.COld Road to Coatepec 351El HayaCP 91073XalapaVeracruzMexico Biostatistics Chair Faculty of Natural Sciences and IMLNational University of TucumánSan Miguel de TucumánMiguel Lillo 2054000 TucumánArgentina

Temperature is a key factor that shapes the distribution of *** knowledge about how species respond to temperature is relevant to devise strategies for addressing the impacts of climate *** insects are particularly vulnerable to climate change,yet there is still much to learn about their ecology and *** the Yungas ecoregion of Northwestern Argentina,cold-and warm-adapted species of the orders Ephemeroptera,Plecoptera,and Trichoptera(EPT)are segregated by *** modeled the ecological niche of South American EPT species in this region using available data and projected their potential distribution in geographic *** were grouped based on their ecogeographic similarity,and we analyzed their replacement pattern along elevation gradients,focusing on the ecotone where opposing thermal preferences *** this interface,we identified critical points where the combined incidence of cold and warm assemblages maximizes,indicating a significant transition *** found that the Montane Cloud Forest holds the interface,with a particularly greater suitability at its lower *** main axis of the interface runs in a N-S direction and falls between 14°C-16°C mean annual *** probability of a particular location within a basin being classified as part of the interface increases as Kira’s warmth index approaches a score around *** the interface is critical for defining the thermal limits of species distribution and designing biomonitoring *** in the location of thermal constants related to mountainous ecotones may cause vertical displacement of aquatic insects and vegetation *** have recognized significant temperature thresholds that serve as indicators of suitability for the *** global warming is anticipated to shift these indicators,we suggest using them to monitor the imprints of climate change on mountain ecosystems.

关键词： Austral Yungas Ecological Niche Model Ephemeroptera Kira’s warmth index Plecoptera Trichoptera

Plant growth and metabolism of exotic and native Crotalaria species for mine land rehabilitation in the Amazon

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Journal of Forestry Research 2024年第1期35卷 143-154页

作者： Hemelyn Soares das Chagas Rafael Silva Guedes Markus Gastauer Paula Godinho ribeiro Allan Klynger da Silva Lobato Cecílio Frois Caldeira Fabrício William deÁvila andréRodrigues dos Reis Silvio Junio Ramos Instituto Tecnológico Vale Rua Boaventura da Silva955BelémPA 66055-090Brazil Universidade Federal do Sul e Sudeste do Pará XinguaraPABrazil Núcleo de Pesquisa Vegetal Básica e Aplicada Universidade Federal Rural da AmazôniaParagominasPABrazil Departamento de Engenharia Florestal Universidade Estadual do Centro-Oeste/UNICENTROIratiPRBrazil School of Sciences and Engineering São Paulo State University(UNESP)TupãSP.CEP 17602-496Brazil

Despite its enormous benefits,mining is respon-sible for intense changes to vegetation and soil ***,after extraction,it is necessary to rehabilitate the mined areas,creating better conditions for the establishment of plant species which is *** study evaluated mineral and organic fertilization on the growth,and carbon and nitrogen(N)metabolism of two Crotalaria species[Cro-talaria spectabilis(exotic species)and Crotalaria maypu-rensis(native species from Carajás Mineral Province(CMP)]established on a waste pile from an iron mine in CMP.A control(without fertilizer application)and six fertilization mixtures were tested(i=NPK;ii=NPK+micronutrients;iii=NPK+micronutrients+organic compost;iv=PK;v=PK+micronutrients;vi=PK+micronutrients+organic compost).Fertilization contributed to increased growth of both species,and treatments with NPK and micronutrients had the best results(up to 257%***),while organic fertilization did not show *** Crotalaria had a greater number of nodules,higher nodule dry mass,chlorophyll a and b contents and showed free ammonium as the predominant N form,reflecting greater increments in biomass compared to native *** having lower growth,the use of this native species in the rehabilitation of mining areas should be considered,mainly because it has good development and meets current government legislation as an opportunity to restore local biodiversity.

关键词： Biological nitrogen fixation Mining Nitrogen metabolism Plant nutrition

The Colíder Paleoproterozoic felsic volcanism:New insights into stratigraphy and petrogenesis in the southern Amazonian Craton

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Geoscience Frontiers 2024年第2期15卷 274-303页

作者： andré Massanobu Ueno Kunifoshita Felipe Holanda dos santos Maria JoséMesquita Instituto de Geociências Universidade Estadual de Campinas(UNICAMP)Rua Carlos Gomes250CEP:13083-855 CampinasSão PauloBrazil Departamento de Geologia Universidade Federal do CearáCampus do PiciBloco 912CEP:60440-554 FortalezaCearáBrazi

The eastern side of Alta Floresta Mineral Province(AFMP)(União do Norte region)comprises an effusive/-subvolcanic phase,explosive phase,and epiclastic *** effusive/subvolcanic phase comprises massive porphyritic rhyolite with different degrees of crystallinity,porphyritic rhyolite with flow structure,and microcrystalline *** explosive phase is characterized by welded lapilli tuff,lapilli tuff with flow structure,stratified lapilli tuff,and tuff with accretionary *** and siltstones characterize epiclastic *** are porphyritic rhyolite dikes that cut the volcanic *** rocks of the Colíder Group are rhyolites(>70%SiO2)with calcic-alkaline to alkaline-calcic affinity.A rhyolitic rock is predominantly ferroan and metaluminous,while a pyroclastic rock is predominantly magnesian to ferroan and meta-to peraluminous in *** rocks have a high LREE content,and slight fractionation of HREE suggests they have hybrid geochemical characteristics of high potassium calc-alkaline,shoshonitic,and suggestive affinities of A-type magmas,probably produced in a post-collisional orogenic *** rocks have a relatively high level of Ba and Rb and a negative anomaly for Sr,P,Nb,Ta,and Ti,suggesting an intra-plate mantle source with contributions from a metasomatized mantle *** rocks do not have adakitic characteristics nor fertility for Cu-Au(Sr/Y<1.9 and LaN/YbN<38.0)as in other regions of the *** welded lapilli tuff rocks show U-Pb age of 1838±17 Ma and 1817±2 Ma and are the older explosive *** effusive/subvolcanic phase has U-Pb ages of 1800±3 Ma and 1792±3 Ma obtained in the massive porphyritic *** age interval of approximately 46 Ma(1838–1792 Ma)suggests the presence of two or more volcanic cycles or distinct volcanic *** on the interpretation of volcanic and epiclastic deposits and remote sensing products,the paleoenvironmental reconstruction includes subaerial with effusive/subvolcani

关键词： Paleoproterozoic volcanism Eroded volcanic caldera Lithofacies analysis Colíder Group Amazonian Craton

Changes in calcium accumulation and utilization efficiency and their impact on recycling,immobilization,and export across the oil palm cycle

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Oil Crop Science 2024年第3期9卷 143-150页

作者： Ismael de Jesus Matos Viégas Luma Castro de Souza Eric Victor de Oliveira Ferreira Milton Garcia Costa Glauco andré dos santos Nogueira Vitor Resende do Nascimento Candido Ferreira de Oliveira Neto Capanema Campus Federal Rural University of the Amazon(UFRA)Av.Barao de CapanemaCaixa D'agua5514-6434ParaBrazil Center of Agricultural and Environmental Sciences Federal University of Maranhao(UFMA)ChapadinhaBR-222km 04SNBoa Vista65500000MaranhaoBrazilc Capitao Poço Campus Federal Rural University of the Amazon(UFRA)Tv.Pau AmareloS/n-Vila Nova68650-000Capitao PoçoParaBrazil Department of Soil Science Sao Paulo State University(Unesp)School of Agricultural and Veterinarian SciencesJaboticabalVia de Acesso Prof.Paulo Donato CastelaneCastellane-S/N-Vila Industrial14884-900Sao PauloBrazil Institute of Agricultural Sciences(ICA) Federal Rural University of the Amazon(UFRA)Estr.Principal da Ufra2150Curio-Utinga66077-580BelemParaBrazil

Effective calcium(Ca)management is crucial for optimizing oil palm cultivation and enhancing crop *** study aimed to gain insights into the dynamics of Ca concentration,accumulation,exportation,immobilization,and recycling in various oil palm organs relative to plant *** experiment was conducted at the Agropalma enterprise site in the northeastern region of Para State,Brazil,evaluating seven plant age treatments:2,3,4,5,6,7,and 8 years *** a completely randomized design with four *** results demonstrated an age-related increase in Ca concentration in petioles,rachis,arrows,male inflorescences,peduncles,and ***,Ca accumulation exhibited an upward trend in all organs with progressing plant ***,the study revealed an enhanced Ca use efficiency across all plant organs in correlation with the age of oil palm *** findings underscore the dynamic nutritional demands of oil palm,influencing Ca immobilization,cycling,and export throughout its developmental stages.

关键词： Elaeis guineensis Jacq Ca cycling Ca export Ca immobilization Ca use efficiency Plant nutrition Amazon

Personalized medicine:Clinical oncology on molecular view of treatment

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World Journal of Clinical Oncology 2024年第8期15卷 992-1001页

作者： Rafick Costa dos santos Da Silva Nathalia de andrade Simon andréAlves dos santos Gabriel De Melo Olegário Jayne Ferreira Da Silva Naide Oliveira Sousa Manuel Alvarez Troncoso Corbacho Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória Da Conquista 45029-094BahiaBrazil

Cancer,the second leading global cause of death,impacts both physically and *** treatments such as surgeries,chemotherapy,and radiotherapy have adverse effects,driving the need for more precise *** medicine enables more targeted *** mapping,alongside other molecular biology approaches,identifies specific genes,contributing to accurate *** review addresses,in clinical use,a molecular perspective on *** like alpha-fetoprotein,beta-human chorionic gonadotropin,5-hydroxyindoleacetic acid,programmed death-1,and cytotoxic T lymphocyte-associated protein 4 are explored,providing valuable ***,with an emphasis on artificial intelligence,revolutionizes the analysis of biological data,offering more accurate *** like liquid biopsy are emphasized for early *** medicine guides therapeutic strategies based on the molecular characteristics of the tumor,as evidenced in the molecular subtypes of breast *** allow personalized treatments,highlighting the role of trastuzumab and endocrine *** the benefits,challenges persist,including high costs,tumor heterogeneity,and ethical *** obstacles requires collaboration,ensuring that advances in molecular biology translate into accessible benefits for all.

关键词： Oncology Neoplasia Molecular biology Personalized medicine Molecular Markers Cancer

Noninvasive Ventilation Interfaces in the Treatment of Acute Respiratory Insufficiency: A Critical Review

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Open Journal of Emergency Medicine 2024年第3期12卷 95-103页

作者： andréa Nóbrega Cirino Nogueira Chakira Torres Lima Renata dos santos Vasconcelos Suzy Maria Montenegro Pontes Arnaldo Aires Peixoto Junior Renan Magalhães Montenegro Junior Clinical Research Unit Walter Cantdio University Hospital Federal University of Cear/EBSERH Fortaleza Brazil

Background: Noninvasive ventilation (NIV) is an important therapeutic modality for the treatment of acute respiratory failure (ARF). In this review, we critically analyze randomized controlled trials on the most used NIV interfaces in the treatments of ARF. Methods: The searches were conducted in the Medline, Lilacs, PubMed, Cochrane, and Pedro databases from June to November 2021. The inclusion criteria were Randomized clinical trials (RCTs) published from 2016 to 2021 in Portuguese, Spanish, or English and involving adults (aged ≥ 18 years). The eligibility criteria for article selection were based on the PICO strategy: Population—Adults with ARF;Intervention—NIV Therapy;Comparison—Conventional oxygen therapy, high-flow nasal cannula (HFNC) oxygen therapy, or NIV;Outcome—improvement in ARF. The search for articles and the implementation of the inclusion criteria were independently conducted by two researchers. Results: Seven scientific articles involving 574 adults with ARF due to various causes, such as chest trauma, decompensated heart failure, coronavirus disease 2019 (COVID-19), and postoperative period, among others, were included. The interfaces cited in the studies included an oronasal mask, nasal mask, full-face mask, and helmet. In addition, some favorable outcomes related to NIV were reported in the studies, such as a reduction in the rate of orotracheal intubation and shorter length of stay in the ICU. Conclusions: The most cited interfaces in the treatment of ARF were the oronasal mask and the helmet.

关键词： Noninvasive Ventilation Respiratory Insufficiency Respiration Artificial Continuous Positive Airway Pressure

TODIM and TOPSIS with Z-numbers

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Frontiers of Information Technology & Electronic Engineering 2019年第2期20卷 283-291页

作者： Renato A.KROHLING andré G.C.PACHECO Guilherme A.dos santos Department of Production Engineering Federal University of Espirito Santo Graduate Program in Computer Science Federal University of Espirito Santo

In this paper, we present an approach that can handle Z-numbers in the context of multi-criteria decision-making problems. The concept of Z-number as an ordered pair Z=(A, B) of fuzzy numbers A and B is used, where A is a linguistic value of a variable of interest and B is a linguistic value of the probability measure of A. As human beings, we communicate with each other by means of natural language using sentences like "the journey from home to university most likely takes about half an hour." The Z-numbers are converted to fuzzy numbers. Then the Z-TODIM and Z-TOPSIS are presented as a direct extension of the fuzzy TODIM and fuzzy TOPSIS, respectively. The proposed methods are applied to two case studies and compared with the standard approach using crisp values. The results obtained show the feasibility of the approach.

关键词： Multi-criteria decision-making TODIM TOPSIS Fuzzy number Z-number

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高压条件下块体碳纳米管的制备(英文)

新型炭材料 2014年第3期29卷 193-202页

作者： Pamela andréa Mantey dos santos Аrea de Ciências Tecnológicas Centro Universitário Franciscano UNIFRA Santa Maria 97010-032 RS Brasil Instituto de Química Universidade Federal do Rio Grande do Sul UFRGS Porto Alegre 91501-970 RS Brasil Instituto de Ffsica Universidade Federal do Rio Grande do Sul UFRGS Porto Alegre 91501-970 RS Brasil) Instituto de Ffsica Universidade Federal do Rio Grande do Sul UFRGS Porto Alegre 91501-970 RS Brasil) Instituto de Ffsica Universidade Federal do Rio Grande do Sul UFRGS Porto Alegre 91501-970 RS Brasil) Instituto de Ffsica Universidade Federal do Rio Grande do Sul UFRGS Porto Alegre 91501-970 RS Brasil

分别以高纯碳纳米管(MWCNTs)、未纯化MWCNTs和盐酸纯化MWCNTs为原料,铅(Pb)和石墨(Gr)为压力传递媒介,在4GPa和7.7GPa高压和室温条件下制备块体碳纳米管。其直径约为6nm,呈圆柱形块体。采用拉曼光谱仪、X-射线衍射仪、氮吸附仪和透射电... 详细信息

分别以高纯碳纳米管(MWCNTs)、未纯化MWCNTs和盐酸纯化MWCNTs为原料,铅(Pb)和石墨(Gr)为压力传递媒介,在4GPa和7.7GPa高压和室温条件下制备块体碳纳米管。其直径约为6nm,呈圆柱形块体。采用拉曼光谱仪、X-射线衍射仪、氮吸附仪和透射电镜表征样品。结果表明,含有MgO催化剂杂质的未纯化MWCNTs,以Pb为媒介时,在7.7GPa下可获得最佳压缩样品。高压可引起MWCNTs压缩和剪切应力。Pb容器作为准静压传递媒介可提供更多压缩应力,同时杂质能作为黏结剂,从而有利于得到致密化度较高的MWCNTs。

关键词：碳纳米管高压块体碳纳米管拉曼光谱透射电镜

Changes on Anuran Tadpole Functional Diversity along an Environmental Gradient at the Southernmost Atlantic Rainforest Remnant

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Asian Herpetological Research 2020年第1期11卷 63-70页

作者： Victor Mendes LIPINSKI andre Passaglia SCHUCH Tiago Gomes dos santos Post Graduation Program of Animal Biodiversity Federal University of Santa MariaLaboratory of HerpetologyDepartment of BiologyAv.Roraima no 1000 building 17room 1140Camobi97105-900Santa MariaRSBrazil Universidade Federal do Pampa Av.Antonio Trilha1847Centro973000000 Sao GabrielRSBrasil Southern Regional Space Research Center CRS/INPE-MCTIP.O.Box 5021room 104197110-970Santa MariaRSBrazil

For decades the ecologists are using the same methods in order to determine the environmental health of a community,however,the crescent need on defining how these processes act,triggered the development of new methods that could classify the organisms and their function at the *** we used the anuran larvae to understand the effects of an environmental gradient on the structure and organization of the anuran assemblages along it,and to access in a realistic form,the actual state of preservation of the la rgest remnant of Atlantic Rainforest on the Southernmost portion of *** found that despite the higher diversity of species and the conservation unit status of the place,the ecosystem itself is still in danger,given the low number of functional groups and thus a higher number of ecosystem services that can be lost.

关键词： Anuran ecosystem function conservation unities tadpoles