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Omicron:increased transmissibility and decreased pathogenicity

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signal transduction and targeted therapy 2022年第6期7卷 1865-1867页

作者： Gábor Bálint Barbara Vörös-Horváth Aleksandar széchenyi Institute of Pharmaceutical technology and Biopharmacy University of PécsFaculty of Pharmacy7624 PécsRókus u.2PécsHungary

three research papers were published recently to compare the virological properties of the Omicron variant with the earlier variants of concern(VOC).1,2,3 the sARs-CoV-2 B.1.1.529 variant,Omicron,was first detected in south Africa in October 2021 and has spread rapidly;within three months,it appeared in more than 87 countries.4 During the surveillance of the epidemiological data and mutations of earlier COVID-19 variants and Omicron,significant differences were revealed mainly in the reproduction rate and hospitalization.

关键词： Omi earlier reproduction

studies on the Electrochemical Reduction of Cyanocobinamide

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Chinese Chemical Letters 1997年第8期8卷 715-718页

作者： Zheng, DH Lu, th Chen, HL ACAD sINICA CHANGCHUN INST APPL CHEMCHANGCHUN 130022PEOPLES R CHINA NANJING UNIV INST COORDINAT CHEMDEPT CHEMNANJING 210008PEOPLES R CHINA

It was found that cyanocobinamide (CN-Cbi) can be reduced at about -0.50V. the reduction process has an EC mechanism, i.e. the electrochemical reduction of CN-Cbi is accompanied by a decyanation of CN-Cbi. the electro... 详细信息

关键词： COBALAMINs

Periodic solutions of Evolution Variational Inequalities—a Method of Guiding Functions

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Chinese Annals of Mathematics,series B 2009年第3期30卷 261-272页

作者： samir ADLY Daniel GOELEVEN Michel thRA Département de Math'ematiques et Informatique Laboratoire XLIM(Unité Mixte 6172 du CNRS)Université de Limoges123 Avenue A.Thomas87060 Limoges CedexFrance. Laboratoire d' Informatique et de Mathématiques Université de La Réunion97400 Saint-DenisFrance.

this paper focuses on a part of the presentation given by the third author at the shanghai Forum on Industrial and Applied Mathematics(shanghai 2006).It is related to the existence of a periodic solution of evolution ... 详细信息

关键词： Variational inequality Differential inclusion topological degree Guiding function Periodic solution

spatial Variability of soil Properties and Rice Yield Along two Catenas in southeast China

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Pedosphere 2008年第4期18卷 409-420页

作者： B. Rth B. LENNARtZ Institute for Land Use University of Rostock Justus-von-Liebig-Weg 6 18059 Rostock (Germany).

In the light of an increasing demand for staple food, especially rice, in southeast China, investigations on the specific site potential expressed as the relationship between soil and crop yield parameters gain increasing importance. soil texture and several soil chemical parameters as well as plant properties such as crop height, biomass and grain yield were investigated along two terraced catenas with contrasting soil textures cropped with wet rice. We were aiming at identifying correlative relationships between soil and crop properties. Data were analyzed both statistically and geostatistically on the basis of semivariograms. statistical analysis indicated a significant influence of the relief position on the spatial distribution of soil texture, total carbon and total nitrogen contents. significant correlations were found for the catena located in a sandstone area (Catena A) between rice yield and silt as well as total nitrogen content. Corresponding relationships were not detectable for paddy fields that developed from Quaternary clays (Catena B). As suggested by the nugget to sill ratio, spatial variability of soil texture, total carbon and nitrogen was mainly controlled by intrinsic factors, which might be attributed to the erosional transport of fine soil constituents, indicating the importance of the relief position and slope in soil development even in landscapes that are terraced. the crop parameters exhibited short ranges of influence and about one third of their variability was unexplained. Comparable ranges of selected crop and soil parameters, found only for Catena A, are indicative of close spatial interactions between rice yield and soil features. Our findings show that especially in sandstone-dominated areas, a site-specific management can contribute to an environmentally safe rice production increase.

关键词： rice productivity semivariogram analysis soil properties spatial data

Existence Results for a Class of Periodic Evolution Variational Inequalities

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Chinese Annals of Mathematics,series B 2007年第6期28卷 629-650页

作者： samir ADLY Daniel GOELEVEN Michel thRA DMI-XLIM UMR-CNRS 6172Université de Limoges123 Avenue A.Thomas87060 Limoges CedexFrance. IREMIA Université de La Réunion97400 Saint-DenisFrance.

In this paper, using the Brouwer topological degree, the authors prove an existence result for finite variational inequalities. this approach is also used to obtain the existence of periodic solutions for a class of e... 详细信息

关键词： Variational inequalities Differential inclusions topological degree Guiding functions Periodic solutions

Characterization of isolated homogeneous hypersurface singularities in C^4

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science China Mathematics 2006年第11期49卷 1576-1592页

作者： YAU stephen s t Department of Mathematics statistics and Computer science University of Illinois at ChicagoChicagoIL 60607-7045USA

Let V be a hypersurface with an isolated singularity at the origin in Cn+1. It is a natural question to ask when V is defined by weighted homogeneous polynomial or homogeneous polynomial up to biholomorphic change of coordinates. In 1971, a beautiful theorem of saito gives a necessary and sufficient condition for V to be defined by a weighted homogeneous polynomial. For a two-dimensional isolated hypersurface singularity V, Xu and Yau found a coordinate free characterization for V to be defined by a homogeneous polynomial. Recently Lin and Yau gave necessary and sufficient conditions for a 3-dimensional isolated hypersurface singularity with geometric genus bigger than zero to be defined by a homogeneous polynomial. the purpose of this paper is to prove that Lin-Yau's theorem remains true for singularities with geometric genus equal to zero.

关键词： homogeneous polynomials, hypersurface singularity, weighted homogeneous polynomial, geometric genus.

Hepatitis B surface Antigen and Hepatitis C Virus Antibodies among Drug Users in Burkina Faso

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Advances in Microbiology 2024年第1期14卷 92-104页

作者： sylvie Zida Kadari Cissé Odette Ky-Zerbo Dinanibè Kambiré serge théophile soubeiga simon tiendrebéogo Fatou sissoko Issa sory Célestine Ki-toé solange Dioma Djeneba Zorom Adama Ouédraogo Cedric Dimitri Axon Hien Mahamoudou sanou seni Kouanda Henri Gautier Ouédraogo Institut de Recherche en sciences de la sant&eacute Ouagadougou Burkina Faso D&eacute partement de G&eacuteographie Universit&eacute Norbert ZONGO Koudougou Burkina Faso secr&eacute tariat permanent du Conseil national de lutte contre le Sida et les IST (SP/CNLS-IST) Ouagadougou Burkina Faso Initiative Priv&eacute e et Communautaire pour la Sant&eacute et la Riposte au VIH/SIDA au Burkina Faso (IPC/BF) Ouagadougou Burkina Faso Unit&eacute de Formation et de Recherche en Sciences de la Sant&eacute (UFR-SDS) Universit&eacute Joseph KI-ZERBO Ouagadougou Burkina Faso

Introduction: the epidemiology of both hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among drug users (DUs) is little known in West Africa. the study aimed to assess the prevalence of hepatitis B and C viruses among drug users in Burkina Faso. Methodology: this was a cross-sectional biological and behavioral survey conducted between June and August 2022, among drug users in Ouagadougou and Bobo Dioulasso, the two main cities of Burkina Faso. A respondent-driven sampling (RDs) was used to recruit drug users. Hepatitis B surface antigen was determined using lateral flow rapid test kits and antibodies to hepatitis C virus in serum determined using an Enzyme-Linked Immunosorbent Assay. Data were entered and analyzed using stata 17 software. Weighted binary logistic regression was used to identify the associated factors of hepatitis B and C infections and a p-value Results: A total of 323 drug users were recruited with 97.5% males. the mean age was 32.7 years old. the inhaled or smoked mode was the most used by drug users. the adjusted hepatitis B and hepatitis C prevalence among study participants were 11.1% and 2.3% respectively. the marital status (p = 0.001), and the nationality (p = 0.011) were significantly associated with hepatitis B infection. the type of drug used was not significantly associated with hepatitis B infection or hepatitis C infection. Conclusion: the prevalence of HBsAg and anti-HCV antibodies among DUs are comparable to those reported in the general population in Burkina Faso. this result suggests that the main routes of contamination by HBV and HCV among DUs are similar to those in the population, and could be explained by the low use of the injectable route by DUs in Burkina Faso.

关键词： Drug Users Hepatitis C Hepatitis B Prevalence Burkina Faso

soft X-ray Properties of Ultraluminous IRAs Galaxies

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Chinese Journal of Astronomy and Astrophysics 2001年第3期1卷 221-223页

作者： Yiao－YangXia th.Boller 等 DepartmentofPhysics TianjinNormalUniversityTianjin300074 Max－Planck－InstitutfuerExtraterrestrischePh

We report on the results of cross-correlation of a sample of 903 Ultraluminous IRAs galaxies (ULIRGs) with the ROsAt-All sky survey Bright source Catalogue and the ROsAt archived pointing observations. the sample of ULIRGs has been compiled from the recently released PsCz redshift survey. In total, 35 ULIRGs are securely detected by the ROsAt All-sky survey and pointing observations, five of which are blazars. the statistical properties of these sources in the soft X-ray band are determined and compared with their properties in other wavebands. We find that the ratio of the soft X-ray to the far-infrared flux spans about five orders of magnitude and reaches Values of about unity. this ratio is a good indicator of the main energy source of ULIRGs. those with soft X-ray to far-infrared flux exceeding 0.01 are probably powered by accretion onto central supermassive black holes while those with ratios smaller than 0.001 are probably powered by starbursts or other heating processes, or are Compton thick sources. some ULIRGs have energy contributions from both. this ratio is low for most ULIRGs and hyperluminous infrared galaxies, which explains their low detection rate by ROsAt and AsCA. We also find that some ULIRGs have a similar soft X-ray luminosity vs. temperature relation to that for groups of galaxies and elliptical galaxies, suggesting a common origin of these systems. Our study also reveals a tight correlation between the hardness ratio and the soft X-ray luminosity for seyfert 1s/QsOs.

关键词： Infrared: galaxies - X-rays: galaxies - Galaxies: active - Galaxies: seyfert - Galaxies: interactions

mi R-122 negatively correlates with liver fibrosis as detected by histology and Fibroscan

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World Journal of Gastroenterology 2015年第25期21卷 7814-7823页

作者： tünde Halász Gábor Horváth Gabriella Pár Klára Werling andrás Kiss Zsuzsa schaff Gábor Lendvai second Department of Pathology Semmelweis University Department of Pathology Military Hospital Hepatology Center of Buda 1111 BudapestHungary First Department of Medicine University of Pécs second Department of Internal Medicine Semmelweis University MtA-sE tumor Progression Research Group Semmelweis University

AIM: to investigate whether expression of selected mi RNAs obtained from fibrotic liver biopsies correlate with fibrosis ***: Altogether, 52 patients were enrolled in the study representing various etiologic backgrounds of fibrosis: 24 cases with chronic hepatitis infections(types B, C), 19 with autoimmune liver diseases(autoimmune hepatitis, primary biliary cirrhosis, primary sclerosing cholangitis, overlapping syndrome cases), and 9 of mixed etiology(alcoholic and nonalcoholic steatosis, cryptogenic cases). severity of fibrosis was determined by both histologic staging using the MEtAVIR scoring system and noninvasive transient elastography. Following RNAisolation, expression levels of mi R-21, mi R-122, mi R-214, mi R-221, mi R-222, and mi R-224 were determined using taq Man Micro RNA Assays applying mi R-140 as the reference. selection of mi RNAs was based on their characteristic up- or downregulation observed in hepatocellular carcinoma. Relative expression of mi RNAs was correlated with fibrosis stage and liver stiffness(Ls) value measured by transient elastography, as well as with serum alanine aminotransferase(ALt) ***: the expression of individual mi RNAs showed deregulated patterns in stages F1-F4 as compared with stage F0, but only the reduced level of mi R-122 in stage F4 was statistically significant(P ssion in relation to fibrosis, levels of mi R-122 and mi R-221 showed negative correlations with fibrosis stage, and mi R-122 was found to correlate negatively and mi R-224 positively with Ls values(all P t levels displayed a positive correlation with mi R-21(P tive correlations were observed in the fibrosis samples of mixed etiology between mi R-122 and fibrosis stage and Ls values(P the samples of chronic viral hepatitis, between mi R-221 and fibrosis stage(P s mi R-21 showed positive correlation with ALt values in the samples of autoimmune live

关键词： Expression Fibroscan Liver fibrosis MEtAVIR microRNA miR-122