检索结果-南通市图书馆

Physiological Response Mechanism and Drought Resistance Evaluation of Passiflora edulis Sims under Drought Stress

Phyton-International Journal of Experimental Botany 2024年第6期93卷 1345-1363页

作者： Binyang Zhao Fengchan Wu Guojun Cai Peiyu Xi Yulin Guo anding Li College of Forestry Guizhou UniversityGuiyang550025China Guizhou Institute of Biology Guizhou Academy of SciencesGuiyang550009China College of Resources and Environment Hunan Agricultural UniversityChangsha410128China

In order to explore the response mechanism of Passiﬂora edulis Sims to drought stress,the changes in morpho-logical and physiological traits of Passiﬂora edulis Sims under different drought conditions were studied.A total of 7 germplasm resources of Passiﬂora edulis Sims were selected and tested under drought stress by the pot culture method under 4 treatment levels:75%–80%(Control,CK)of maximumﬁeld water capacity,55%–60%(Light Drought,LD)of maximumﬁeld water capacity,i.e.,mild drought,40%–45%(Moderate Drought,MD)of max-imumﬁeld water capacity,i.e.,moderate drought and 30%–35%(Severe Drought,SD)of maximumﬁeld water capacity,i.e.,severe *** the 40th day of drought treatment,1. indices,including seedling growth mor-phology,physiology,and biochemistry,were *** results showed that under drought stress,the height and ground diameter of *** Sims gradually decreased with increasing drought stress,and there were signiﬁ-cant differences in seedling height and ground diameter among the *** stress signiﬁcantly inhib-ited the growth of seven *** Sims *** contents of soluble sugar(SS),soluble protein(SP),proline(Pro),and other substances in *** Sims basically increased with increasing drought *** the aggrava-tion of drought stress,the malondialdehyde(MDA)content of *** Sims tended to increase to different degrees,the superoxide dismutase(SOD)activity and peroxidase(POD)activity both tended to increase atﬁrst and then decrease,and the change in catalase(CAT)activity mostly showed a gradual increasing *** con-tents of endogenous hormones in *** Sims signiﬁcantly differed under different degrees of drought *** the aggravation of drought stress,the abscisic acid(ABA)content of *** Sims tended to increase,whereas the contents of gibberellin(GA),indoleacetic acid(IAA),and zeatin nucleoside(ZR)exhibited a down-ward trend.A comprehensive evaluation of the drought resistance of seven *** Sim

关键词： Drought resistance water stress phytohormone morphological trait physiological traits

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

烟台市中西部及邻区的水库淤积

引用

山地学报 2004年第1期22卷 79-86页

作者：杜国云刘贤赵王庆高桂颂张安定烟台师范学院地理与资源管理学院招远市水务局烟台师范学院地理与资源管理学院山东烟台　264025 山东招远　265400

将水库淤积按沉积动力学特征分为河流沉积淤积和水库沉积淤积两种基本类型,相映建立了两种淤积动力模型。枯水期水库水位下降时,河流沉积淤积体较水库沉积淤积体有较大面积的出露,枯水期淤积面积构成了水库淤积体大小及淤积程度的重要... 详细信息

将水库淤积按沉积动力学特征分为河流沉积淤积和水库沉积淤积两种基本类型,相映建立了两种淤积动力模型。枯水期水库水位下降时,河流沉积淤积体较水库沉积淤积体有较大面积的出露,枯水期淤积面积构成了水库淤积体大小及淤积程度的重要侧面和重要参数,水库淤积程度是枯水期水库淤积面积的函数。结合陆地卫星TM图像,对研究区内的30个水库淤积状况统计后,按淤积程度离差分为三级:Ⅰ级,DEPDEV1.Ⅲ级,DEPDEV>1.对图像平面数据与水利部门实测的水库淤积量数据进行对比,发现图像数据与兴利库容以下实测数据协同性好。最后,分别在流域内及整个研究区域,对水库淤积程度的空间分布进行了分析。

关键词：烟台市中西部 TM图像水库淤积区域变化

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Increased retinal venule diameter as a prognostic indicator for recurrent cerebrovascular events:a prospective observational study

引用

Neural Regeneration Research 2024年第5期19卷 1156-1160页

作者： Ying Zhao Dawei Dong Ding Yan Bing Yang Weirong Gui Man Ke anding Xu Zefeng Tan Department of Neurology and Stroke Center the First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong ProvinceChina Clinical Neuroscience Institute the First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong ProvinceChina Department of Neurology the First People’s Hospital of FoshanFoshanGuangdong ProvinceChina

Microvasculature of the retina is considered an alternative marker of cerebral vascular risk in healthy ***,the ability of retinal vasculature changes,specifically focusing on retinal vessel diameter,to predict the recurrence of cerebrovascular events in patients with ischemic stroke has not been determined *** previous studies have shown a link between retinal vessel diameter and recurrent cerebrovascular events,they have not incorporated this information into a predictive ***,this study aimed to investigate the relationship between retinal vessel diameter and subsequent cerebrovascular events in patients with acute ischemic ***,we sought to establish a predictive model by combining retinal veessel diameter with traditional risk *** performed a prospective observational study of 1.1.patients with acute ischemic stroke who were admitted to the First Affiliated Hospital of Jinan *** of these patients underwent digital retinal imaging within 72 hours of admission and were followed up for 3 *** found that,after adjusting for related risk factors,patients with acute ischemic stroke with mean arteriolar diameter within 0.5-1.0 disc diameters of the disc margin(MAD_(0.5-1.0DD))of≥74.1.μm and mean venular diameter within 0.5-1.0 disc diameters of the disc margin(MVD_(0.5-1.0DD))of≥83.91.m tended to experience recurrent cerebrovascular *** established three multivariate Cox proportional hazard regression models:model 1.included traditional risk factors,model 2 added MAD_(0.5-1.0DD)to model 1.and model 3 added MVD0.5-1.0DD to model *** 3 had the greatest potential to predict subsequent cerebrovascular events,followed by model 2,and finally model *** findings indicate that combining retinal venular or arteriolar diameter with traditional risk factors could improve the prediction of recurrent cerebrovascular events in patients with acute ischemic stroke,and that retinal imaging c

关键词： acute ischemic stroke arteriolar cerebrovascular events diameter digital retinal imaging microvasculature prediction recurrent retina venular

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons

引用

Neural Regeneration Research 2024年第4期19卷 908-914页

作者： Yalan Chen Junxin Kuang Yimei Niu Hongyao Zhu Xiaoxia Chen Kwok-Fai So anding Xu Lingling Shi Guangdong-Hong Kong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan University Department of Neurology and Stroke Center The First Affiliated HospitalJinan University Department of Psychiatry The First Affiliated HospitalJinan University Co-innovation Center of Neuroregeneration Nantong University

Midbrain dopaminergic neurons play an important role in the etiology of neurodevelopmental and neurodegenerative *** also represent a potential source of transplanted cells for therapeutic *** vitro differentiation of functional midbrain dopaminergic neurons provides an accessible platform to study midbrain neuronal dysfunction and can be used to examine obstacles to dopaminergic neuronal *** evidence and impressive advances in human induced pluripotent stem cells,with tuned neural induction and differentiation protocols,makes the production of induced pluripotent stem cell-derived dopaminergic neurons *** SB431.42 and dorsomorphin dual inhibitor in an induced pluripotent stem cell-derived neural induction protocol,we obtained multiple subtypes of neurons,including 20%tyrosine hydroxylase-positive dopaminergic *** obtain more dopaminergic neurons,we next added sonic hedgehog(SHH)and fibroblast growth factor 8(FGF8)on day 8 of *** increased the proportion of dopaminergic neurons,up to 75%tyrosine hydroxylase-positive neurons,with 1.%tyrosine hydroxylase and forkhead box protein A2(FOXA2)co-expressing *** further optimized the induction protocol by applying the small molecule inhibitor,CHIR99021.CHIR).This helped facilitate the generation of midbrain dopaminergic neurons,and we obtained 31.74%midbrain dopaminergic neurons based on tyrosine hydroxylase and FOXA2 ***,we have established three induction protocols for dopaminergic *** on tyrosine hydroxylase and FOXA2 immunostaining analysis,the CHIR,SHH,and FGF8 combined protocol produces a much higher proportion of midbrain dopaminergic neurons,which could be an ideal resource for tackling midbrain-related diseases.

关键词： dopaminergic neurons FGF signal induced pluripotent stem cells midbrain neural differentiation SHH signal SMAD signal WNT signal

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Penumbra-targeted CircOGDH siRNA-loaded nanoparticles alleviate neuronal apoptosis in focal brain ischaemia

引用

Stroke & Vascular Neurology 2024年第2期9卷 134-144,I0396-I0413页

作者： Yanfang Liu Tianyuan Zhang Xing Zou Zhongwen Yuan Yufeng Li Jiankun Zang Niu He Lizhen He anding Xu Dan Lu Department of Neurology and Stroke Center Jinan University First Affiliated HospitalGuangzhouGuangdongChina Department of Clinical Neuroscience Institute The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdongChina Key Lab of Guangzhou Basic and Translational Research of Pan-vascular Diseases The First Affiliated Hospital of Jinan UniversityGuangzhouChina

Background Nanoparticles(NPs)are a class of substances that can be loaded with therapeutic agents delivered to specific *** our earlier research,we identified a neuron-derived circular RNA(circRNA),circular oxoglutarate dehydrogenase(CircOGDH),as a promising therapeutic target for acute ischaemic *** study dedicated to explore a prospective preliminary strategy of CircOGDH-based NP delivered to the ischaemic penumbra region in middle cerebral artery occlusion/reperfusion(MCAO/R)*** Immunofluorescence in primary cortex neurons and in vivo fluorescence imaging revealed endocytosis of Poly(lactide-co-glycolide)(PLGA)poly amidoamine(PAMAM)@CircOGDH small interfering RNA(siRNA)*** blotting analysis and CCK8 assay were performed to evaluate the apoptotic level in ischaemic neurons treated with PLGA–PAMAM@CircOGDH siRNA *** reverse transcription PCR experiments,mice behaviour test,T2 MRI analysis,Nissl and TdT-mediated dUTP nick end labeling(TUNEL)co-staining were performed to evaluate the apoptosis level of ischaemic penumbra neurons in MCAO/R *** evaluation of NPs in MCAO/R mice was detected by blood routine examination,liver and kidney function examination and HE *** PLGA–PAMAM@CircOGDH siRNA NPs were successfully *** of PLGA–PAMAM@CircOGDH siRNA NPs in ischaemic neurons alleviated neuronal apoptotic level in vitro and in ***,mice behaviour test showed that the neurological defects of MCAO/R mice were significantly alleviated after the tail injection of PLGA–PAMAM@CircOGDH siRNA NPs,and no toxic effects were *** In conclusion,our results suggest that PLGA–PAMAM@CircOGDH siRNA NPs can be delivered to the ischaemic penumbra region and alleviate neuron apoptosis in MCAO/R mice and in ischaemic neurons;therefore,our study provides a desirable approach for using circRNA-based NPs for the treatment of ischaemic stroke.

关键词： OGD routine loaded

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Atherosclerosis-related biomarker PABPC1.predicts pan-cancer events

引用

Stroke & Vascular Neurology 2024年第2期9卷 108-125,I0001-I0005页

作者： Miao Lin Liubing Hu Si Shen Jiyue Liu Yanyan Liu Yixian Xu Honglin Chen Kazuo Sugimoto Jianshuang Li Ikuo Kamitsukasa Takaki Hiwasa Hao Wang anding Xu Stroke Center The First Affiliated HospitalJinan UniversityGuangzhouChina Department of Anesthesiology The First Affiliated HospitalJinan UniversityGuangzhouChina The Biomedical Translational Research Institute Faculty of Medical ScienceJinan UniversityGuangzhouChina Department of Radiology Medical Imaging CenterThe First Affiliated HospitalJinan UniversityGuangzhouChina Department of Biochemistry and Genetics Graduate School of MedicineChiba UniversityChibaJapan Department of Neurology Dongzhimen HospitalBeijing University of Chinese MedicineBeijingChina Department of Neurology Chiba Rosai HospitalChibaJapan Department of Neurology Chibaken Saiseikai Narashino HospitalChibaJapan Department of Neurological Surgery Graduate School of MedicineChiba UniversityChibaJapan

Background Atherosclerosis(AS)and tumours are the leading causes of death worldwide and share common risk factors,detection methods and molecular ***,searching for serum markers shared by AS and tumours is beneficial to the early diagnosis of *** The sera of 23 patients with AS-related transient ischaemic attack were screened by serological identification of antigens through recombinant cDNA expression cloning(SEREX),and cDNA clones were *** function enrichment analysis was performed on cDNA clones to identify their biological pathways and determine whether they were related to AS or ***,gene–gene and protein–protein interactions were performed and AS-associated markers would be *** expression of AS biomarkers in human normal organs and pan-cancer tumour tissues were ***,immune infiltration level and tumour mutation burden of various immune cells were *** curves analysis could show the expression of AS markers in *** AS-related sera were screened by SEREX,and 83 cDNA clones with high homology were *** functional enrichment analysis,it was found that their functions were closely related to AS and tumour *** multiple biological information interaction screening and the external cohort validating,poly(A)binding protein cytoplasmic 1.PABPC1.was found to be a potential AS *** assess whether PABPC1.was related to pan-cancer,its expression in different tumour pathological stages and ages was *** AS-associated proteins were closely related to cancer immune infiltration,we investigated and found that PABPC1.had the same role in ***,analysis of Kaplan-Meier survival curves revealed that high PABPC1.expression in pan-cancer was associated with high risk of *** Through the findings of SEREX and bioinformatics pan-cancer analysis,we concluded that PABPC1.might serve as a potential biomarker for the

关键词： diagnosis cancer organs

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Thrombus migration in patients with acute ischaemic stroke undergoing endovascular thrombectomy

引用

Stroke & Vascular Neurology 2024年第2期9卷 126-133,I0006-I0395页

作者： ZeFeng Tan Lei Zhang Li'an Huang Hongyu Qiao Min Guan Bing Yang Pengfei Yang Yongwei Zhang Hongjian Shen Yu Zhou Bo Hong Huaizhang Shi Hongxing Han Xinyi Leng Yi Dong Changlin Lian Wenhuo Chen anding Xu Jianmin Liu Neurology First People's Hospital of FoshanFoshanGuangdongChina Department of Neurology Jinan University First Affiliated HospitalGuangzhouGuangdongChina Neurovascular Center Changhai HospitalNaval Medical UniversityShanghaiChina Department of Neurosurgery First Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Neurology Linyi People's HospitalLinyiShandongChina Medicine&Therapeutics The Chinese University of Hong KongHong KongChina Neurology Huashan Hospital Fudan UniversityShanghaiChina Neurology Zhangzhou Municipal Hospital of Fujian Province and Zhangzhou Affiliated Hospital of Fujian Medical UniversityZhangzhouFujianChina Stroke Center Jinan University First Affiliated HospitalGuangzhouGuangdongChina

Objective The impact of thrombus migration(TM)prior to endovascular thrombectomy(EVT)on clinical outcomes and revascularisation rates remains *** aimed to examine whether preinterventional TM modifies the treatment effects of direct EVT versus bridging EVT in acute large vessel occlusion *** All patients undergoing catheter angiography in the Direct Intra-arterial thrombectomy in order to Revascularise acute ischaemic stroke patients with large vessel occlusion Efficiently in Chinese Tertiary hospitals:A Multicentre randomised clinical Trial were *** was determined by radiologists unaware of the study by analysing discrepancies between computed tomographic angiography at baseline and first-run digital subtraction angiography before *** primary outcome was the score on the modified Rankin scale(mRS)assessed at 90 *** Of 627 included patients,the TM rate was 1..3%(71.627).In the multivariable logistic regression model,baseline National Institutes of Health Stroke Scale score(adjusted OR 0.956,95%CI 0.91. to 0.999;p=0.043)and intravenous thrombolysis(adjusted OR 2.61.,95%CI 1.51. to 4.51.;p1.were independently associated with *** patients with TM were less likely to be completely recanalised than those without TM(21.27%vs 36.23%,p=0.040).The interaction of TM and the EVT treatment effect did not significantly affect mRS shift analysis(p=0.687)or mRS scores of 0 to 1.p=0.436).Conclusion Preinterventional TM does not modify the treatment effects of direct versus bridging EVT on functional outcomes in patients with acute ischaemic stroke with anterior large vessel *** leads to a lower complete recanalisation rate.

关键词： patients throm acute

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

正则化相场格子玻尔兹曼两相流模型

引用

力学学报 2024年第8期56卷 2259-2270页

作者：李游李贵李桥忠代安定牛小东湖南城市学院理学院湖南益阳413000 湖南城市学院土木工程学院湖南益阳413000 江苏科技大学船舶与海洋工程学院江苏镇江212100 汕头大学机械电子工程系广东汕头515063

目前,基于相场理论的格子玻尔兹曼(lattice Boltzmann,LB)模型已经被广泛应用于气-液两相流流动问题中.为了提高已有相场LB模型的数值稳定性,提出了一种新型的正则化相场格子玻尔兹曼模型(regularized lattice Boltzmann model,RLBM)用... 详细信息

目前,基于相场理论的格子玻尔兹曼(lattice Boltzmann,LB)模型已经被广泛应用于气-液两相流流动问题中.为了提高已有相场LB模型的数值稳定性,提出了一种新型的正则化相场格子玻尔兹曼模型(regularized lattice Boltzmann model,RLBM)用于模拟大密度比和大黏度比的气液两相流动.该模型由界面追踪和流场求解两个核心模块构成,其中界面变化采用守恒型Allen-Cahn (A-C)相场方程控制,流场演化则通过不可压NavierStokes (N-S)方程控制.首先,构建了两个正则化格子玻尔兹曼方程(lattice Boltzmann equation,LBE)分别获取流场信息和相场信息.与标准的单松弛模型不同的是,提出的模型在演化方程的碰撞项中引入了非平衡态的预前碰撞函数,且该预前碰撞项仅与宏观量有关.通过Chapman-Enskog (C-E)多尺度展开分析,证实了所提出的模型能够准确地恢复到宏观流场控制方程和相场控制方程.进一步地,为了验证本模型的有效性,模拟了4个两相流典型算例,包括静态液滴、Rayleigh-Taylor(R-T)不稳定性问题、气泡上升和单个液滴撞击液膜.数值结果证实了提出的模型能够准确地模拟大密度比、大黏度比、大雷诺数下的气液两相流流动问题.更重要的是,相较于传统的相场单松弛模型在小的迁移率(θ_(M)1.^(-2))下就会诱发数值方法不收敛的问题,提出的模型在模拟迁移率较小(θ_(M)=1.0×1.^(-6))的复杂两相流动时表现出更好的稳定性,能够更准确地刻画界面流动,捕捉界面形态.

关键词：正则化相场模型气-液两相流 Allen-Cahn方程格子玻尔兹曼方法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

互花米草侵入滩涂生态修复路径探索

引用

港口航道与近海工程 2024年第3期61卷 146-150页

作者：葛安定中交第一航务工程勘察设计院有限公司天津300220

滨海湿地是近海生物重要栖息繁殖地和鸟类迁徙中转站,具有重要的生态功能,江苏如东湿地是国家重点保护的湿地之一,保护并及时修复受损沿海生态意义重大。本文结合具体项目,探索通过人工割除、维护性疏浚弃土覆盖、良性植被替代相组合的... 详细信息

滨海湿地是近海生物重要栖息繁殖地和鸟类迁徙中转站,具有重要的生态功能,江苏如东湿地是国家重点保护的湿地之一,保护并及时修复受损沿海生态意义重大。本文结合具体项目,探索通过人工割除、维护性疏浚弃土覆盖、良性植被替代相组合的方式,探索修复被互花米草入侵破坏的沿海生态的路径,为沿海生态保护一体化项目提供借鉴。

关键词：互花米草侵入生态修复

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

化工火灾事故的风险管理策略探讨

引用

化工管理 2024年第21期 113-116页

作者：刘安定无锡市消防救援支队滨湖大队江苏无锡214100

文章在分析化工火灾事故风险管理现状的基础上,从风险评估、预警系统、消防设施配置、应急响应机制等方面,提出了优化风险管理的对策建议,通过构建多维度火灾风险评估模型、提升预警系统智能化水平等措施,可有效提升化工企业火灾风险防... 详细信息

文章在分析化工火灾事故风险管理现状的基础上,从风险评估、预警系统、消防设施配置、应急响应机制等方面,提出了优化风险管理的对策建议,通过构建多维度火灾风险评估模型、提升预警系统智能化水平等措施,可有效提升化工企业火灾风险防控能力。文章还通过实际案例的分析,论证了相关策略的可行性与有效性,为化工企业火灾风险管理实践提供了参考。

关键词：化工火灾风险管理智能预警

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：