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Issues with Tropical and Temperate Ensilage Protein and Amino Acid Feeds Utilization: A Research Note

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Agricultural Sciences 2022年第11期13卷 1177-1185页

作者： Danny Agustin Flores Skye blue Internet Port Coquitlam Brit. Columbia Canada

Alfalfa protein breakdown was to soluble NPN of oligopeptide-N, AA-N, amide-N, amine-N and NH3-N. Acidity (pH) and moisture (Aw) are critical in determining extent of fermentation and changes in composition. Further changes in digestive flows and post-prandial plasma AA are indicators of protein status. Dual-purpose cropping and tree plant cropping was with ensiling management of the undergrowth. On-farm field-drying and probiotic additives are promising. It is suggested acidity with propionic acid and microbial inoculants together with field-drying and chop length are required to optimize profile qualities in silage. It is proposed use of denaturing with acid and dust cropping with a hypothetical PNA-Auxin repressor to plant protease. Further study with field-drying to follow is needed. Feeding HIS, ARG and LEU AA supplement to change GRH and GH profiles could be used to promote LBM in production. Dual-purpose cropping can expand subsistence to mixed farming with expanded livestock products and services and resources. PNA-Auxin and PNA-ARF penetrates the plant shoot tips to deliver a TF mRNA to boost proteins in residual cell tissues. Ensiled % AA-N delivery per os to per duodenum was higher;yet total AA-N flow was higher in the control. It is suggested that “bulk” flow was less but with a “tighter” conversion on TAA. FAA was 145% higher in the ensiled versus the fresh control indicating the ENU with less PFAA supplied. FAA on the ensiled diet is high inferred to be more soluble and escape lower from the rumen. WSC are less supplied in fermented forage with VFA being lower and presenting the question whether WSC should be supplied for energy and also with EFE through breaking down of polymers of lignocellulose. It was surmised, although not known, that higher dilution rate (% hr-1) was true on the fresh diet compared to the ensiled although end-products may initially detract with feed but that further digestion in the fresh feed may be higher with intake

关键词： Silage Protein Degradation Duodenal Amino Acid Flows Plasma Amino Acids Protein Utilization

Geodiversity in the Yellow River source zone

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Journal of Geographical Sciences 2013年第5期23卷 775-792页

作者： Brendon blue Gary BRIERLEY YU Guo-an School of Environment University of Auckland Private Bag 92019 Auckland New Zealand Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China

It is a key premise of ＇ecosystem approaches＇ to natural resources management that we must have an appropriate understanding of biodiversity values, and controls upon them, if we wish to manage them effectively. These biodiversity values, and associated ecosystem functionality, vary with space and time and are tied directly to landscape-scale relationships and evolutionary traits. In riverine systems, nested hierarchical principles provide a useful platform to assess relationships between landscape components across a range of scales. These understandings are most instructively synthesized through catchment-scale analyses. This paper outlines a rationale for systematic catchment-wide appraisals of river geodiversity. An initial application of these principles is presented for the Yellow River source zone in Qinghai Province, western China. Geo-ecological relationships are outlined for five broad sections of the trunk stream, highlighting implications for the management of these individual landscape compartments and for the system as a whole.

关键词： geodiversity river classification anabranching Qinghai-Tibet Plateau Sanjiangynan Yellow River source zone

Store-operated calcium channels and pro-inflammatory signals

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Acta Pharmacologica Sinica 2006年第7期27卷 813-820页

作者： Wei-chiao CHANG~1 Department of Physiology,anatomy and Genetics,University of Oxford,Oxford,UK Department of Physiology Anatomy and Genetics University of Oxford Oxford UK

In non-excitable cells such as T lymphocytes,hepatocytes,mast cells,endotheliaand epithelia,the major pathway for calcium(Ca2+)entry is through store-oper-ated Ca2+channels in the plasma *** channels are activated by theemptying of intracellular Ca2+stores,however,neither the gating mechanism northe downstream targets of these channels has been clear ***,Ireview some of the proposed gating mechanisms of store-operated Ca2+channelsand the functional implications in regulating pro-inflammatory signals.

关键词： calcium channels store-operated Ca2+ entry capacitative Ca2+entry calcium signaling mast cells

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2022年SaaS安全调查7大焦点

网络安全技术与应用 2022年第6期 F0002-F0002,F0003页

作者： blue 不详

2022年SaaS(软件即服务,SaaS Software-as-a-Service的简称)安全调查报告与CSA合作,调查了当今企业CISO和安全专业人员眼中的SaaS安全态势。该报告收集了340名CSA成员的匿名回复,不仅调查了SaaS安全中日益增长的风险,而且还调查了不同... 详细信息

2022年SaaS(软件即服务,SaaS Software-as-a-Service的简称)安全调查报告与CSA合作,调查了当今企业CISO和安全专业人员眼中的SaaS安全态势。该报告收集了340名CSA成员的匿名回复,不仅调查了SaaS安全中日益增长的风险,而且还调查了不同组织目前如何确保自身安全。

关键词：软件即服务 SaaS 安全态势自身安全 Service 匿名调查报告

Using the ROSS optical streak camera as a tool to understand laboratory experiments of laser-driven magnetized shock waves

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High Power Laser Science and Engineering 2018年第2期6卷 63-68页

作者： Andy Liao Patrick Hartigan Gennady Fiksel Brent blue Peter Graham John Foster Carolyn Kuranz Rice University USA University of Michigan-Ann Arbor USA Lawrence Livermore National Laboratory USA Awe Plc UK

Supersonic flows with high Mach number are ubiquitous in astrophysics. High-powered lasers also have the ability to drive high Mach number, radiating shock waves in laboratory plasmas, and recent experiments along these lines have made it possible to recreate analogs of high Mach-number astrophysical flows under controlled conditions. Streak cameras such as the Rochester optical streak system(ROSS) are particularly helpful in diagnosing such experiments,because they acquire spatially resolved measurements of the radiating gas continuously over a large time interval,making it easy to observe how any shock waves and ablation fronts present in the system evolve with time. This paper summarizes new ROSS observations of a laboratory analog of the collision of a stellar wind with an ablating planetary atmosphere embedded within a magnetosphere. We find good agreement between the observed ROSS data and numerical models obtained with the FLASH code, but only when the effects of optical depth are properly taken into account.

关键词： laser optical systems plasma astrophysics

Genetic approach to track neural cell fate decisions using human embryonic stem cells

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Protein & Cell 2014年第1期5卷 69-79页

作者： Xuemei Fu Zhili Rong Shengyun Zhu Xiaocheng Wang Yang Xu blue B. Lake Shenzhen Children's Hospital Shenzhen 518026 China Section of Molecular Biology Division of Biological Sciences University of California San Diego 9500 Gilman Drive LaJolla CA 92093-0322 USA

With their capability to undergo unlimited self-renewal and to differentiate into all cell types in the body, human embryonic stem cells （hESCs） hold great promise in human cell therapy. However, there are limited tools for easily identifying and isolating live hESC-derived cells. To track hESC-derived neural progenitor cells （NPCs）, we applied homologous recombination to knock-in the mCherry gene into the Nestin locus of hESCs. This facilitated the genetic labeling of Nestin positive neural progenitor cells with mCherry. Our reporter system enables the visualization of neural induction from hESCs both in vitro （embryoid bodies） and in vivo （ter- atomas）. This system also permits the identification of different neural subpopulations based on the intensity of our fluorescent reporter. In this context, a high level of mCherry expression showed enrichment for neural progenitors, while lower mCherry corresponded with more committed neural states. Combination of mCherry high expression with cell surface antigen staining enabled further enrichment of hESC-derived NPCs. These mCherry＊ NPCs could be expanded in culture and their differentiation resulted in a down-regulation of mCherry consistent with the loss of Nestin expression. Therefore, we have developed a fluorescent reporter system that can be used to trace neural differentiation events of hESCs.

关键词： Nestin knock-in human embryonic stemcells neural progenitor cells

Analysis of controls upon channel planform at the First Great Bend of the Upper Yellow River, Qinghai-Tibet Plateau

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Journal of Geographical Sciences 2013年第5期23卷 833-848页

作者： LI Zhiwei WANG Zhaoyin PAN Baozhu DU Jun Gary BRIERLEY YU Guo-an Brendon blue State Key Laboratory of Hydroscience and Engineering Tsinghua University Beijing 100084 China Changjiang River Scientific Research Institute Wuhan 430010 China School of Environment University of Auckland Private Bag 92019 Auckland New Zealand Key Laboratory of Water Cycle and Related Land Surface Processes Institute of Geographic Sciences and Natural Resources Research CAS Beijing 100101 China

The 270 km long section of the Upper Yellow River at the First Great Bend is comprised of single channel and multiple channel systems that alternate among anastomosing, anabranching, meandering and braided reaches. The sequence of downstream pattern changes is characterized as： anastomosing-anabranching, anabranching-meandering, meandering-braided and braided-meandering. Remote sensing images, DEM data and field investigations are used to assess ahd interpret controls on these reach transitions. Channel slope and bed sediment size are key determinants of transitions in channel planform. Anas- tomosing reaches have a relatively high bed slope （0.86‰） and coarser sediment bed material （d50 = 3.5 mm）. In contrast, meandering reaches have a low slope （0.30‰） and fine sediment bed material （d50 = 0.036 mm）. The transition from a meandering to braided pattern is characterized by an increase in channel width-depth ratio, indicating the important role of bank strength （i.e. cohesive versus non-cohesive versus channel boundaries）. Interestingly, the braided-meandering and meandering-braided transitions are coincident with variable flow inputs from tributary rivers （Baihe and Heihe rivers respectively）. Theoretical analysis of the meandering-braided transition highlights the key control of channel width-depth ratio as a determinant of channel planform.

关键词： Yellow River Source river pattern diversity river pattern transition anastomosing river ana- branching river meandering river braided river

DNA fragmentation in apoptosis

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Cell Research 2000年第3期10卷 205-211页

作者： ZHANG JIAN HUA, MING XU (Department of Cell Biology, Neurobiology and anatomy, University of Cincinnati College of Medicine, Cincinnati, Ohio 452670521, USA) Department of Cell Biology Neurobiology and Anatomy University of Cincinnati College of Medicine Cincinnati USA

Cleavage of chromosomal DNA into oligonucleosomal size fragments is an integral part of apoptosis. Elegant biochemical work identified the DNA fragmentation factor (DFF) as a major apoptotic endonuclease for DNA fragmentation in vitro. Genetic studies in mice support the importance of DFF in DNA fragmentation and possibly in apoptosis in vivo. Recent work also suggests the existence of additional endonucleases for DNA degradation. Understanding the roles of individual endonucleases in apoptosis, and how they might coordinate to degrade DNA in different tissues during normal development and homeostasis, as well as in various diseased states, will be a major research focus in the near future.

关键词： DNA fragmentation DFF endonucleases apop tosts.

Matrix metalloproteinases and their expression in mammary gland

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Cell Research 1998年第3期8卷 187-194页

作者： URIA JOSE A ZENA WERB(Department of anatomy, University of California San Francisco, CA 94143-0452, USA) Department of anatomy University of California San Francisco CA USA

The matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that play a key role in both normal and pathological processes involving tissue remodeling events. The expression of these proteolytic enzymes is highly regulated by a balance between extracellular matrix (ECM) deposition and its degradation, and is controlled by growth factors, cytokines, hormones, as well as interactions with the ECM macromolecules. Furthermore, the activity of the MMPs is regulated by their natural endogenous inhibitors, which are members of the tissue inhibitor of metalloproteinases (TIMP) family. In the normal mammary gland, MMPs are expressed during ductal development, lobulo-alveolar development in pregnancy and involution after lactation. Under pathological conditions, such as tumorigenesis, the dysregulated expression of MMPs play a role in tumor initiation, progression and malignant conversion as well as facilitating invasion and motastasis of malignant cells through degradation of the ECM and basement membranes. Matrix metalloproteinases and their expression in mammary gland

关键词： Matrix metalloproteinases ECM cancer progression mammary gland