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Large-scale genome-wide SNP analysis reveals the rugged(and ragged)landscape of global ancestry,phylogeny,and demographic history in chicken breeds

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Journal of Zhejiang University-Science b(biomedicine & biotechnology) 2024年第4期25卷 324-340页

作者： Natalia V.DEMENTIEVA Yuri S.SHCHERbAKOV Olga I.STANISHEVSKAYA anatoly b.vakhrameev Tatiana A.LARKINA Artem P.DYSIN Olga A.NIKOLAEVA Anna E.RYAbOVA Anastasiia I.AZOVTSEVA Olga V.MITROFANOVA Grigoriy K.PEGLIVANYAN Natalia R.REINbACH Darren K.GRIFFIN Michael N.ROMANOV Russian Research Institute of Farm Animal Genetics and breeding-branch of the L.K.Ernst Federal Research Centre for Animal Husbandry.Pushkin St.Petersburg196601Russia School of biosciences University of KentCanterburyCT27NJUK L.K.Ernst Federal Research Center for Animal Husbandry DubrovitsyPodolskMoscow Oblast142132Russia

The worldwide chicken gene pool encompasses a remarkable,but shrinking,number of divergently selected breeds of diverse *** study was a large-scale genome-wide analysis of the landscape of the complex molecular architecture,genetic variability,and detailed structure among 49 *** populations represent a significant sample of the world's chicken breeds from Europe(Russia,Czech Republic,France,Spain,UK,etc.),Asia(China),North America(USA),and Oceania(Australia).based on the results of breed genotyping using the Illumina 60K single nucleotide polymorphism(SNP)chip,a bioinformatic analysis was carried *** included the calculation of heterozygosity/homozygosity statistics,inbreeding coefficients,and effective population *** also included assessment of linkage disequilibrium and construction of phylogenetic *** multidimensional scaling,principal component analysis,and ADMIXTURE-assisted global ancestry analysis,we explored the genetic structure of populations and subpopulations in each *** overall 49-population phylogeny analysis was also performed,and a refined evolutionary model of chicken breed formation was proposed,which included egg,meat,dual-purpose types,and ambiguous *** a large-scale survey of genetic resources in poultry farming using modern genomic methods is of great interest both from the viewpoint of a general understanding of the genetics of the domestic chicken and for the further development of genomic technologies and approaches in poultry *** general,whole genome SNP genotyping of promising chicken breeds from the worldwide gene pool will promote the further development of modern genomic science as applied to poultry.

关键词： Chicken genome diversity Single nucleotide polymorphism(SNP)analysis Gene pool Global ancestry Phylogeny Demographic history

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Gradient-induced long-range optical pulling force based on photonic band gap

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Light(Science & Applications) 2024年第5期13卷 865-874页

作者： Wenlong Lu Alexey V.Krasavin Sheng Lan anatoly V.Zayats Qiaofeng Dai Guangdong basic Research Center of Excellence for Structure and Fundamental Interactions of Matter Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and DevicesSchool of Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhou 510006China Department of Physics and London Centre for Nanotechnology King’s College LondonLondon WC2R 2LSUK

Optical pulling provides a new degree of freedom in optical *** is generally believed that long-range optical pulling forces cannot be generated by the gradient of the incident ***,we theoretically propose and numerically demonstrate the realization of a long-range optical pulling force stemming from a self-induced gradient field in the manipulated *** analogy to potential barriers in quantum tunnelling,we use a photonic band gap design in order to obtain the intensity gradients inside a manipulated object placed in a photonic crystal waveguide,thereby achieving a pulling *** the usual scattering-type optical pulling forces,the proposed gradient-field approach does not require precise elimination of the reflection from the manipulated *** particular,the Einstein-Laub formalism is applied to design this unconventional gradient *** magnitude of the force can be enhanced by a factor of up to 50 at the optical resonance of the manipulated object in the waveguide,making it insensitive to *** developed approach helps to break the limitation of scattering forces to obtain longrange optical pulling for manipulation and sorting of nanoparticles and other *** developed principle of using the band gap to obtain a pulling force may also be applied to other types of waves,such as acoustic or water waves,which are important for numerous applications.

关键词： optical waveguide scattering

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Regulation of apoptosis in the ischemic penumbra in the first day post-stroke

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Neural Regeneration Research 2020年第2期15卷 253-254页

作者： anatoly b.Uzdensky Laboratory of Molecular Neurobiology Academy of Biology and Biotechnology Southern Federal University

Stroke is one of leading causes of human disability and death. More than 17 million stroke incidences occur in the world each year. In ischemic stroke (70-80% of all strokes) cerebral vessel occlusion quickly, for few... 详细信息

关键词： human disability apoptosis depletion,

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Axotomy induces damage to glial cells remote from the transection site in the peripheral nervous system

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Neural Regeneration Research 2018年第4期13卷 639-640页

作者： anatoly b.Uzdensky Laboratory of Molecular Neurobiology Academy of Biology and BiotechnologySouthern Federal University

Traumatic cerebral or spinal cord injury induced by military,traffic,and sports accidents,falls or environmental and anthropogenic catastrophes are among main causes of people mortality and disability,especially in yo... 详细信息

关键词： Axotomy induces damage to glial cells remote from the transection site in the peripheral nervous system CSR

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Histone acetylation and deacetylation in ischemic stroke

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Neural Regeneration Research 2021年第8期16卷 1529-1530页

作者： anatoly b.Uzdensky Svetlana Demyanenko Laboratory of Molecular Neurobiology Academy of Biology and BiotechnologySouthern Federal UniversityRostov-on-DonRussia

Stroke is the second leading cause of death in the world. A significant part of survived people become invalids, dependent on others and in need of outside care. This is a heavy burden for their families and society. The life of patients surviving ischemic stroke(~80% of all strokes) may be subdivided by three main phases:(a) The acute phase that lasts about first 24 hours, when the neurons may be saved and the neuroprotective therapy may be efficient;(b) The early recovery phase that lasts for several days and weeks, when the repair and regeneration processes develop, and partial recovery of brain functions occurs;and (c) The chronic phase(weeks, months and years)。

关键词： protective acute death

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Short-term reliability evaluation for power stations by using Lz-transform

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Journal of Modern Power Systems and Clean Energy 2013年第2期1卷 110-117页

作者： anatoly LISNIANSKI Hanoch bENHAIM Reliability Department The Israel Electric Corporation1 Nativ HaOr StreetP.O.B.10HaifaIsrael

A short-term reliability evaluation is used for power stations,where each power generating unit is presented by a multi-state Markov *** main obstacle for reliability evaluation in such a case is a“curse of dimensionality”—a great(huge)number of states of entire power station that should be analyzed.A modern approach is proposed based on using Lz-transform that drastically simplifies *** proposed approach is useful for power system security analysis and short-term operating *** order to illustrate the proposed approach,the short-term reliability evaluation for a power station with different coal fired generating units is presented.

关键词： Power system Generating unit Generating capacity Multi-State Markov model Lz-transform Universal generating function

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Plasma-Assisted Chemistry in High-Speed Flow

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Plasma Science and Technology 2007年第6期9卷 760-765页

作者： Sergey b.LEONOV Dmitry A.YARANTSEV anatoly P.NAPARTOVICH Igor V.KOCHETOV Joint Institute for High Temperature Russian Academy of Science Izhorskaya str.13/19Moscow 125412Russia State

Fundamental problems related to the high-speed combustion are analyzed. The result of plasma-chemical modeling is presented as a motivation of experimental activity. Numerical simulations of the effect of uniform non-equilibrium discharge on the premixed hydrogen and ethylene-air mixture in supersonic flow demonstrate an advantage of such a technique over a heating. Experimental results on multi-electrode non-uniform discharge maintenance behind wallstep and in cavity of supersonic flow are presented. The model test on hydrogen and ethylene ignition is demonstrated at direct fuel injection to low-temperature high-speed airflow.

关键词： high-speed combustion electrical discharge nonequilibrium kinetics

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3,6-bis(2,2,2-trinitroethylnitramino)-1,2,4,*** and energy abilities as a component of solid composite propellants

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Defence Technology（防务技术） 2022年第7期18卷 1148-1155页

作者： anatoly G.Korepin Natalia M.Glushakova David b.Lempert anatoly I.Kazakov Gennady V.Shilov Denis V.Korchagin Vadim M.Volokhov Elena S.Amosova Sergey M.Aldoshin Institute of Problems of Chemical Physics Ac.Semenov Avenue 1Chernogolovka142432Russian Federation

The work addresses to the study of the molecular and crystal structure and properties of a new energyintensive compound 3,6-bis(2,2,2-trinitroethylnitramino)-1,2,4,5-tetrazine(NbTAT),first obtained by the authors in *** compound crystallizes in the monoclinic system,space group P2(1)/n,density at room temperature 1.939 g/cm^(3).The energies of crystal packing and pairwise intermolecular interactions in NbTAT and its unnitrated analogue bTAT were calculated,and their comparative analysis was carried *** enthalpy of formation of NbTAT molecules was calculated by quantum-chemical methods using Gaussian 09,and the enthalpy of formation of NbTAT in the solid phase(618 kJ/mol)was *** energy capabilities of NbTAT as an oxidizer of solid composite propellants are *** is shown that in metal-free compositions NbTAT is significantly superior to ammonium perchlorate(AP),dinitramide ammonium salt(ADN),HMX,bTAT at all stages of rocket systems,and is comparable to the superdense CL-20 yielding to the latter at the lower stages and slightly winning at the upper stages.

关键词： Nitrogen heterocycles Quantum chemistry Enthalpy of formation 3,6-bis(2,2,2-trinitroethylnitramino)-1,2,4,5-tetrazine Crystal structure Energetic ability

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Characterization and Electrochemical Properties of Nanostructured Zr-Doped Anatase TiO_2 Tubes Synthesized by Sol–Gel Template Route

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Journal of Materials Science & Technology 2017年第6期33卷 527-534页

作者： Denis P.Opra Sergey V.Gnedenkov Sergey L.Sinebryukhov Elena I.Voit Alexander A.Sokolov Evgeny b.Modin anatoly b.Podgorbunsky Yury V.Sushkov Veniamin V.Zheleznov Institute of Chemistry Far Eastern Branch of Russian Academy of Sciences Far Eastern Federal University National Research Centre "Kurchatov Institute"

A series of nanostructured Zr-doped anatase TiO_2 tubes with the Zr/Ti molar ratio of 0.01, 0.02, 0.03, and0.09 were prepared by a sol–gel technology on a carbon fiber template. The electrochemical performance of Zr-doped anatase TiO_2 as anodes for rechargeable lithium batteries was investigated and compared with undoped titania. Tests represented that after 35-fold charge/discharge cycling at C/10 the reversible capacity of Zr-doped titania（Zr/Ti = 0.03） reaches 135 m A h g^（-1）, while the capacity of undoped titania（Zr/Ti = 0） yielded only 50 m A h g^（-1）. based on the results of the physicochemical investigation, three reasons of improving electrochemical performance of Zr-doped titania were suggested. According to the scanning electron microscopy and transmission electron microscopy, Zr^（4＋） doping induces a decrease in nanoparticle size, which facilitates the Li＋diffusion. The Raman investigations show the more open structure of Zr-doped TiO_2 as compared to undoped titania due to changing of the unit cell parameters, that significantly affects on the reversibility of the insertion/extraction process. The electrochemical impedance spectroscopy results indicate that substitution of Zr^（4＋） for Ti^（4＋） into anatase TiO_2 has favorable effects on the conductivity.

关键词： Li-ion batteries Anatase titania Nanostructured materials Sol–gel template process Doping Electrochemical performance

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New Facts in Regression Estimation under Conditions of Multicollinearity

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Open Journal of Statistics 2016年第5期6卷 842-861页

作者： anatoly Gordinsky berman Engineers LTD Modiin Israel

This paper considers the approaches and methods for reducing the influence of multi-collinearity. Great attention is paid to the question of using shrinkage estimators for this purpose. Two classes of regression models are investigated, the first of which corresponds to systems with a negative feedback, while the second class presents systems without the feedback. In the first case the use of shrinkage estimators, especially the Principal Component estimator, is inappropriate but is possible in the second case with the right choice of the regularization parameter or of the number of principal components included in the regression model. This fact is substantiated by the study of the distribution of the random variable , where b is the LS estimate and β is the true coefficient, since the form of this distribution is the basic characteristic of the specified classes. For this study, a regression approximation of the distribution of the event based on the Edgeworth series was developed. Also, alternative approaches are examined to resolve the multicollinearity issue, including an application of the known Inequality Constrained Least Squares method and the Dual estimator method proposed by the author. It is shown that with a priori information the Euclidean distance between the estimates and the true coefficients can be significantly reduced.

关键词： Linear Regression Multicollinearity Two Classes of Regression Models Shrinkage Estimators Inequality Constrained Least Squres Estimator Dual Estimator

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