检索结果-南通市图书馆

Study of biological markers in skin quality treatment by subcutaneous injection of a stabilized composition of 26 mg/mL of high molecular weight HA

引用

Plastic and Aesthetic Research 2022年第1期9卷 539-552页

作者： Jérémie Bon Bétemps Samuel Gavard Molliard Basste Hadjab Mhd Badi anas ghazal Marco Cerrano Research and Development Department Kylane Laboratoires SAPlan-les-Ouates 1228Switzerland Art Clinic Riyadh 12432Saudi Arabia Derma Clinic Jeddah 23432Saudi Arabia Entourage Clinique Lausanne 1003Switzerland

Aim:Hyaluronic acid(HA)injectables have gained rapid acceptance for the treatment of skin rejuvenation.A novel HA/sorbitol composition intended for skin quality improvement containing 2.6%of high molecular weight HA stabilized by sorbitol was recently designed to be injected *** aim of this study was to assess the expression of biological markers of skin quality after administration of the ***:The HA/sorbitol composition was evaluated after injection into the superficial adipose tissue with ex vivo cultured human skin explants versus a product comparator to study the general morphology of the skin tissues and the expression of HA,elastin,collagen type Ⅰ,collagen type Ⅲ,and fibrillin-1 in the dermal ***:The results demonstrate that the HA/sorbitol composition is able to boost the production of HA,elastin,collagen type Ⅰ,collagen type Ⅲ,and fibrillin-1 in the dermis while providing a proper quality of skin ***:The HA/sorbitol composition improved biological markers of skin quality in the dermis after product injection into the superficial adipose *** novel composition can be considered as an attractive solution to treat skin aging by injecting a specific HA/sorbitol formulation to strategically target the subcutaneous tissue to improve the quality of the different layers of the skin.

关键词： Facial aging hyaluronic acid sorbitol skin quality biological markers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stabilized composition of 26 mg/mL of high molecular weight HA for subcutaneous injection to improve skin quality

引用

Plastic and Aesthetic Research 2022年第1期9卷 564-575页

作者： Samuel Gavard Molliard Jérémie Bon Bétemps Basste Hadjab anas ghazal Mhd Badi Marco Cerrano Department of Research and Development Kylane Laboratoires SAPlan-les-Ouates 1228Switzerland Department of Clinic Derma ClinicJeddah 23432Saudi Arabia Department of Clinic Art ClinicRiyadh 12432Saudi Arabia Department of Clinic Entourage CliniqueLausanne 1003Switzerland

Aim:Skin firmness is one of the key parameters to define skin quality and facial *** the minimally invasive anti-aging strategies,hyaluronic acid(HA)injection is widely accepted to improve skin *** most of the available HA injectables are designed and intended for intradermal injection,a novel HA/sorbitol composition containing 2.6% high molecular weight hyaluronic acid stabilized by sorbitol was recently developed to be specifically injected into the adipose tissue to improve the quality of all skin layers,especially the skin ***:The HA/sorbitol composition was investigated versus product comparators in terms of biophysical properties,tolerance in subcutaneous tissue with in vivo implantation study,and skin firmness assessment on human skin ***:The HA/sorbitol composition was characterized by unique and differentiated biophysical properties,proper distribution and high tolerance of the gel composition into the adipose tissue,and the ability to efficiently improve skin ***:The HA/sorbitol composition represents a new attractive solution to treat facial skin aging with an injection strategy specifically targeting the adipose tissue instead of the dermis,to improve the quality of the skin.

关键词： Facial aging hyaluronic acid sorbitol biophysical properties skin quality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：