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Detection and Classification of Diabetic Retinopathy Using DCNN and BSN Models

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Computers, Materials & Continua 2022年第7期72卷 597-609页

作者： S.Sudha A.srinivasan T.Gayathri Devi Department of ECE SRCSASTRA Deemed UniversityKumbakonamIndia

Diabetes is associated with many complications that could lead to *** retinopathy,a complication of diabetes,is difficult to diagnose and may lead to vision *** identification of micro features in fundus images for the diagnosis of DR is a complex and challenging task for *** clinical testing involves complex procedures and is timeconsuming,an automated system would help ophthalmologists to detect DR and administer treatment in a timelymanner so that blindness can be *** research works have focused on image processing algorithms,or neural networks,or signal processing techniques alone to detect diabetic ***,we aimed to develop a novel integrated approach to increase the accuracy of *** approach utilized both convolutional neural networks and signal processing *** this proposed method,the biological electro retinogram(ERG)sensor network(BSN)and deep convolution neural network(DCNN)were developed to detect and classify *** the BSN system,electrodes were used to record ERGsignal,which was preprocessed to be *** was performed in the frequency domain by the application of fast Fourier transform(FFT)and mel frequency cepstral coefficients(MFCCs)were *** neural network(ANN)classifier was used to classify the signals of eyes with DR and normal ***,fundus images were captured using a fundus camera,and these were used as the input for DCNN-based *** DCNN consisted of many layers to facilitate the extraction of features and classification of fundus images into normal images,non-proliferative DR(NPDR)or earlystage DR images,and proliferative DR(PDR)or advanced-stage DR ***,it classifiedNPDRaccording tomicroaneurysms,hemorrhages,cotton wool spots,and exudates,and the presence of new blood vessels indicated *** accuracy,sensitivity,and specificity of the ANNclassifier were found to be 94%,95%,and 93%,***

关键词： Deep convolution neural network artificial neural network nonproliferative diabetic retinopathy biological ERG sensor network

Anti-diabetic activity of quercetin extracted from Phyllanthus emblica ***: In silico and in vivo approaches

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Journal of Pharmaceutical Analysis 2018年第2期8卷 109-118页

作者： Prabhu srinivasan S.Vijayakumar Swaminathan Kothandaraman Manogar Palani Computational Phytochemistry Lab PG and Research Department of Botany and Microbiology A. V. V. M Sri Pushpam College (Autonomous) Department of Physics RKM Vivekananda College (Autonomous)

In this study, molecular interactions of the ligands, quercetin, gallic acid, and metformin with various diabetes mellitus-related protein targets, such as glycogen phosphorylase and peroxisome proliferatoractivated receptor gamma, were assessed. It was revealed that quercetin possesses good binding affinity to both targets. Quercetin is a major constituent of methanolic extracts of Phyllanthus emblica fruit. The antihyperglycemic effect of quercetin in streptozotocin(STZ)-induced diabetic rats was examined. The isolated quercetin administered at a dose of 75 mg/kg body weight produced a maximum decrease of14.78% in blood glucose levels in the diabetic rats after 7 days of treatment. Furthermore, quercetin doses of 50 and 75 mg/kg were shown to significantly improve the profiles of triglycerides, high-density lipoprotein, very-low-density lipoprotein, low-density lipoprotein, and total cholesterol at the end of the study in STZ-induced diabetic rats. The administration of quercetin(25, 50, and 75 mg/kg body weight)daily for 28 days in STZ-induced diabetic rats resulted in a significant decrease in blood glucose and urine sugar levels, with a considerable rise in plasma insulin and hemoglobin levels. Therefore, quercetin is a potential drug with antidiabetic and antihyperglycemic action mediated by changes in the levels of glucose, cholesterol, and triglycerides as indicated by in silico and in vivo studies.

关键词： Bioactive molecules Glycogen phosphorylase Molecular docking Phyllanthus emblica Quercetin Albino Wister male rats

Structural, Thermal, Linear and Nonlinear Optical Studies on New NLO Crystal∶DL-Threonium Trichloroacetate

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Journal of Rare Earths 2006年第Z1期24卷 249-252页

作者： Gubendiran Ramesh Kumar srinivasan Gokul Raj Rajagopal Mohan Ramasamy Jayave Department of Physics Presidency college Chennai-600 005 India Department of Physics Presidency college Chennai-600 005 India Department of Physics Presidency college Chennai-600 005 India Department of Physics Presidency college Chennai-600 005 India Crystal Growth Centre Anna University Chennai-600 025 India

Crystals of DL-threonium trichloroacetate (DLTTCA) was synthesized from an aqueous solution by slow evaporation technique. The grown crystals were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, UV-Vis-NIR and SHG measurements. Vibrational structure of the crystal was elucidated from FTIR analysis and the hydrogen bond interactions were discussed in detail. The ultraviolet transparent cutoff falls at 212 nm. Thermal stability of the compound was also studied. The powder SHG efficiency of the compound was measured as 0.62 times to that of KDP.

关键词： growth from solution nonlinear optical materials

Electrochemical corrosion behavior of acid treated strip cast AM50 and AZX310 magnesium alloys in 3.5 wt.% NaCl solution

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Journal of Magnesium and Alloys 2017年第3期5卷 277-285页

作者： srinivasan Arthanari Rajendran Nallaiyan Shin Kwang Seon Magnesium Technology Innovation Center School of Materials Science and EngineeringSeoul National University1 Gwanak-roGwanak-guSeoul 08826Republic of Korea Department of Chemistry Anna UniversityChennai 600025TamilnaduIndia

The influence of acid treatments on the surface morphology and electrochemical corrosion behavior of strip-cast AM50 and AZX310 alloys have been studied in the present *** alloys were acid treated using H_(3)PO_(4)(AT-1),HF(AT-2)and HNO3(AT-3)for different treatment durations viz.,60,300 and 600 *** acid treatments produced a surface layer consisting of corresponding magnesium salts of the acids and were confirmed from the X-ray diffraction(XRD),scanning electron microscopy(SEM)and energy dispersive X-ray analysis(EDAX).AT-1 treatment produced cracked and network porous morphology for AM50 and AZX310 alloys respectively andAT-3 treatment exhibited dense creaked surface layer formation while AT-2 does not produce any significant change in the *** studies revealed that,the acid treatment significantly altered the corrosion process by altering anodic and cathodic reaction rates of AM50 and AZX310 *** HNO3(AT-3)treatment was effective compared to other treatments to control the corrosion rate in the studied treatment *** surface morphology and chemical composition of surface layer produced during the treatment was correlated to explain the corrosion results.

关键词： Magnesium Pretreatment Corrosion Acid treatment Polarization

CURE CHARACTERISTICS OF HYDROXYL TERMINATED POLYBUTADIENE PREPOLYMER WITH BLOCKED TOLUENE DIISOCYANATE-Ⅰ

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Chinese Journal of Polymer Science 1993年第3期11卷 284-291页

作者： Prathima Kamath M.srinivasan V.N.Krishnamurthy Department of Chemistry Indian Institute of Technology Madras 600 036 INDIADepartment of Chemistry Indian Institute of Technology Madras 600 036 INDIAVikram Sarabhai Space Centre Trivandrum 695 022INDIA

Controlled release of TDI and hence the cure characteristics of several blocked TDI with HTPB are reported. The reactions were followed through viscosity measurements as a function of time and temperature under the catalytic influence of triethylamine. The effect of nature of substituents present on the end capping substrate, temperature, solvent, basicity of catalyst and kinetics thereon have been studied.

关键词： Blocked TDI HTPB Cure characteristics Toluene diisocyanate

Networking Controller Based Real Time Traffic Prediction in Clustered Vehicular Adhoc Networks

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Intelligent Automation & Soft Computing 2023年第2期35卷 2189-2203页

作者： T.S.Balaji S.srinivasan Saveetha School of Engineering Saveetha Institute of Medical and Technical SciencesSaveetha UniversitySaveetha NagarThandalamChennai602105India Department of Electronics and Communication Engineering College of Engineering and TechnologySRM Institute of Science and TechnologyVadapalani CampusChennai600026India Department of Biomedical Engineering Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesSaveetha UniversitySaveetha NagarThandalamChennai602105India

The vehicular ad hoc network(VANET)is an emerging network tech-nology that has gained popularity because to its low cost,ﬂexibility,and seamless *** deﬁned networking(SDN)technology plays a critical role in network administration in the future generation of VANET withﬁfth generation(5G)*** of the beneﬁts of VANET,energy economy and trafﬁc control are signiﬁcant architectural *** and real-time trafﬁcﬂow prediction(TFP)becomes critical for managing trafﬁc effectively in the *** controllers are a critical issue in VANET,which has garnered much interest in recent *** this objective,this study develops the SDNTFP-C technique,a revolutionary SDN controller-based real-time trafﬁcﬂow forecasting technique for clustered *** proposed SDNTFP-C technique combines the SDN controller’s scalability,ﬂexibility,and adaptability with deep learning(DL)***,a novel arithmetic optimization-based clustering technique(AOCA)is developed to cluster automobiles in a *** TFP procedure is then performed using a hybrid convolutional neural network model with atten-tion-based bidirectional long short-term memory(HCNN-ABLSTM).To optimise the performance of the HCNN-ABLSTM model,the dingo optimization techni-que was used to tune the hyperparameters(DOA).The experimental results ana-lysis reveals that the suggested method outperforms other current techniques on a variety of evaluation metrics.

关键词： VANET trafﬁcﬂow prediction clustering metaheuristics SDN controller deep learning

Evaluation of Insulin Resistance Markers and Their Relationship with ADIPO Q Gene Polymorphism in Clinically Euthyroid Type 2 Diabetic Patients

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Biomedical and Environmental Sciences 2022年第6期35卷 543-546页

作者： Rajendran Jayanthi anandaraj Lokeshmaran Ramasamy Sathiya Abu Raghavan srinivasan Departments of Biochemistry and Community Medicine Mahatma Gandhi Medical College&Research InstituteSri Balaji VidyapeethPondicherry–607402

Insulin resistance(IR)has a nexus with metabolic *** homeostatic model assessment for insulin resistance(HOMA-IR),HOMA-β,quantitative insulin sensitivity check index(QUICKI),glucoseinsulin ratio,and triglyceride(TAG)/high density lipoprotein(HDL)have been increasingly recognized as insulin sensitivity/resistance markers[1].Hyperinsulinemic euglycemic clamp(HEC),the gold standard,has inherent practical demerits and thus paves the way for a simplified but objectivized approach to quantifying insulin sensitivity/resistance.

关键词： Marker Patients lipoprotein

CURE CHARACTERISTICS OF HYDROXYL TERMINATED POLYBUTADIENE PREPOLYMER WITH BLOCKED TOLUENE DIISOCYANATE-Ⅱ

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Chinese Journal of Polymer Science 1994年第1期12卷 91-97页

作者： Prathima Kamath M.srinivasan V.N.Krishnamurthy Department of Chemistry Indian Institute of Technology Madras-600036 INDIADepartment of Chemistry Indian Institute of Technology Madras-600036 INDIAVikram Sarabhai Space Centre Trivandrum-695022 INDIA

Cure characteristics of hydroxyl terminated polybutadiene (HTPB) prepolymer with avariety of blocked toluene diisocyanate (TDI) in the presence of triethylamine (TEA) andchloroacetic acid catalyst are reported. Phenol, thiophenol, p-chloropheno1, p-nitrophenol,p-cresol, resorcinol, naphthols, caprolactam and butylated-hydroxytoluene were used as blockingagents. Viscosity measurements have been carried out using a mixture of HTPB and blocked TDIin cyclohexanone in the presence of the catalysts at 50℃ and 60℃ using Haake rotational vis-cometer. Viscosity measurements have also been carried out with 50% solids such as ammonium sulphate along with HTPB and TDI adduct.

关键词： Hydroxyl terminated polybutadiene Blocked toluene diisocyanate Cure characteristics

Optimal Solution of Fuzzy Transportation Problem Using Octagonal Fuzzy Numbers

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Computer Systems Science & Engineering 2021年第6期37卷 415-421页

作者： D.Gurukumaresan C.Duraisamy R.srinivasan Department of Mathematics Kongu Engineering CollegeErode638060India Department of Ancient Science Faculty of ScienceTamil UniversityThanjavur613010India

In this paper a fuzzy transportation problem under a fuzzy environment is solved using octagonal fuzzy *** transportation problem is significant and has been widely studied in the field of applied mathematics to solve a system of linear equations in many applications in *** of concurrent linear equations play a vital major role in operational *** main perspective of this research paper is to find out the minimum amount of transportation cost of some supplies through a capacitated network formerly the availability and the demand notes are octagonal fuzzy *** fuzzy numbers are used and showed a membership *** illustrate this method,a fuzzy transportation problem is solved by using octagonal fuzzy numbers using the ranking *** is shown that it is the best optimal solution and it is demonstrated with a numerical example.

关键词： Linear equation transportation problem fuzzy transportation problem ranking technique trapezoidal fuzzy numbers