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Severe gastrointestinal mucositis following high dose melphalan therapy for multiple myeloma

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World Journal of Gastroenterology 2013年第5期19卷 784-785页

作者： Sanjeev Kumar Sharma Anil Handoo Dharma Choudhary gaurav Dhamija Nitin Gupta Department of Hemato-oncology and Bone Marrow Transplant BLK Superspeciality HospitalNew Delhi 110005India

Mucositis is a known complication following use of chemotherapy,but fatal mucositis is unusual and management of such cases may be *** there is denudation of mucosa of gastrointestinal tract. Severe cases can develop ileus and even perforation of bowel *** report here a case of multiple myeloma who developed World Health Organization grade 4 gut mucositis following the use of high dose melphalan with the expulsion of"intestine-like"material.

关键词： Gastrointestinal mucositis Chemotherapy

Design and implementation of various datapath architectures for the ANU lightweight cipher on an FPGA

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Frontiers of Information Technology & Electronic Engineering 2020年第4期21卷 615-628页

作者： Vijay DAHIPHALE gaurav BANSOD Ankur ZAMBARE Narayan PISHAROTY Pune Institute of Computer Technology Pune 411043India Iziel Healthcare Pvt.Ltd. Pune 411028India

Since the dawn of the Internet of Things(IoT),data and system security has been the major concern for *** most IoT devices operate on 8-bit controllers with limited storage and computation power,encryption and decryption need to be implemented at the transmitting and receiving ends,respectively,using lightweight *** present novel architectures for hardware implementation for the ANU cipher and present results associated with each *** ANU cipher is implemented at 4-,8-,16-,and 32-bit datapath sizes on four different field-programmable gate array(FPGA)platforms under the same implementation condition,and the results are compared on every performance *** previous ANU architectures,the new architectures have parallel substitution boxes(S-boxes)for high throughput and hardware *** these different datapath designs,ANU cipher proves to be the obvious choice for implementing security in extremely resourceconstrained systems.

关键词： Lightweight cryptography Internet of Things(IoT) Embedded security Encryption FPGA Datapath design

Eminence of Microbial Products in Cosmetic Industry

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Natural Products and Bioprospecting 2019年第4期9卷 267-278页

作者： Prabhuddha LGupta Mahendrapalsingh Rajput Tejas Oza Ujwalkumar Trivedi gaurav Sanghvi Department of Microbiology Marwadi UniversityRajkot 360001India

Cosmetology is the developing branch of science,having direct impact on the *** cosmetic sector is interested in finding novel biological alternatives which can enhance the product attributes as well as it can substitute chemical *** of the compounds are having biological origin and are acquire from bacteria,fungi,and algae.A range of biological compounds,like bio-surfactant,vitamins,antioxidants,pigments,enzymes,peptides have promising features and beneficial ***,these products can be produced commercially with *** review will encompass the importance and use of microbial compounds for new cosmetic formulations as well as products associated with it.

关键词： Cosmetics Microbiology Biosurfactants Formulations Cyclodextrin Emulsions

A GPU-Accelerated Mixed-Precision WENO Method for Extremal Black Hole and Gravitational Wave Physics Computations

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Communications on Applied Mathematics and Computation 2023年第1期5卷 97-115页

作者： Scott E.Field Sigal Gottlieb Zachary J.Grant Leah F.Isherwood gaurav Khanna University of Massachusetts Dartmouth North DartmouthMA 02747USA Department of Computational and Applied Mathematics Oak Ridge National LaboratoryOak RidgeTN 37830USA University of Rhode Island KingstonRI 02881USA

We develop and use a novel mixed-precision weighted essentially non-oscillatory(WENO)method for solving the Teukolsky equation,which arises when modeling perturbations of Kerr black *** show that WENO methods outperform higher-order finite-difference methods,standard in the discretization of the Teukolsky equation,due to the need to add dissipation for stability purposes in the *** particular,as the WENO scheme uses no additional dissipation,it is well suited for scenarios requiring long-time evolution such as the study of price tails and gravitational wave emission from extreme mass ratio *** the mixed-precision approach,the expensive computation of the WENO weights is performed in reduced floating-point precision that results in a significant speedup factor of≈*** addition,we use state-of-the-art Nvidia general-purpose graphics processing units and cluster parallelism to further accelerate the WENO *** optimized WENO solver can be used to quickly generate accurate results of significance in the field of black hole and gravitational wave *** apply our solver to study the behavior of the Aretakis charge—a conserved quantity,that if detected by a gravitational wave observatory like LIGO/Virgo would prove the existence of extremal black holes.

关键词： Numerical methods-Finite differencing Hyperbolic Partial differential equations Black holesblack holes WENO

Antiarthritic effects of Ajuga bracteosa Wall ex *** acute and chronic models of arthritis in albino rats

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Asian Pacific Journal of Tropical Biomedicine 2012年第3期2卷 185-188页

作者： gaurav Kaithwas Raju Gautam Sanjay M Jachak Arvind Saklani Department of Pharmaceutical Sciences Assam University Department of Natural Products National Institute of Pharmaceutical Education and Research(NIPER) Department of Natural Products 1-Nirlon ComplexPiramal Life Sciences

Objective:To evaluate the antiarthritic activity of Ajuga bracteosa using albino ***: The antiarthritic activity of 70%ethanolic extract of Ajuga bracteosa(EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant(CFA)-induced chronic immunological arthritis in albino ***:EEAB showed a significant(P<0.05) and dose dependent inhibitory effect against acute and chronic models of *** exhibited better antiarthritic activity than the standard ***: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.

关键词： Ajuga bracteosa Adjuvant Formaldehyde Turpentine Cyclooxygenase

Addressing Economic Dispatch Problem with Multiple Fuels Using Oscillatory Particle Swarm Optimization

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Computers, Materials & Continua 2021年第12期69卷 2863-2882页

作者： Jagannath Paramguru Subrat Kumar Barik Ajit Kumar Barisal gaurav Dhiman Rutvij HJhaveri Mohammed Alkahtani Mustufa Haider Abidi KIIT University BhubaneswarOdishaIndia Department of Electrical Engineering CETBhubaneswarOdishaIndia Department of Computer Science Government Bikram College of CommercePatialaIndia Department of Computer Science&Engineering Pandit Deendayal Petroleum UniversityGandhinagarIndia Raytheon Chair for Systems Engineering Advanced Manufacturing InstituteKing Saud UniversityRiyadh11421Saudi Arabia Industrial Engineering Department College of EngineeringKing Saud UniversityRiyadh11421Saudi Arabia

Economic dispatch has a significant effect on optimal economical operation in the power systems in industrial revolution 4.0 in terms of considerable savings in *** non-linearity are added to make the fossil fuel-based power systems more *** order to achieve an accurate economical schedule,valve point loading effect,ramp rate constraints,and prohibited operating zones are being considered for realistic *** this paper,an improved,and modified version of conventional particle swarm optimization(PSO),called Oscillatory PSO(OPSO),is devised to provide a cheaper schedule with optimum *** conventional PSO is improved by deriving a mechanism enabling the particle towards the trajectories of oscillatory motion to acquire the entire search space.A set of differential equations is implemented to expose the condition for trajectory motion in *** adaptive inertia weights,this OPSO method provides an optimized cost of generation as compared to the conventional particle swarm optimization and other new meta-heuristic approaches.

关键词： Economic load dispatch valve point loading industry 4.0 prohibited operating zones ramp rate limit oscillatory particle swarm optimization

SSABA:Search Step Adjustment Based Algorithm

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Computers, Materials & Continua 2022年第6期71卷 4237-4256页

作者： Fatemeh Ahmadi Zeidabadi Ali Dehghani Mohammad Dehghani Zeinab Montazeri Stepán Hubálovsky Pavel Trojovsky gaurav Dhiman Department of Mathematics and Computer Sciences Sirjan University of TechnologySirjanIran Department of Civil Engineering Islamic Azad UniversityEstahban BranchEstahbanIran Department of Mathematics Faculty of ScienceUniversity of Hradec KrálovéHradec Králové50003Czech Republic Department of Electrical and Electronics Engineering Shiraz University of TechnologyShirazIran Department of Applied Cybernetics Faculty of ScienceUniversity of Hradec KrálovéHradec Králové50003Czech Republic Department of Computer Science Government Bikram College of CommercePatialaPunjabIndia

Finding the suitable solution to optimization problems is a fundamental challenge in various *** algorithms are one of the effective stochastic methods in solving optimization *** this paper,a new stochastic optimization algorithm called Search StepAdjustment Based Algorithm(SSABA)is presented to provide quasi-optimal solutions to various optimization *** the initial iterations of the algorithm,the step index is set to the highest value for a comprehensive search of the search ***,with increasing repetitions in order to focus the search of the algorithm in achieving the optimal solution closer to the global optimal,the step index is reduced to reach the minimum value at the end of the algorithm *** is mathematically modeled and its performance in optimization is evaluated on twenty-three different standard objective functions of unimodal and multimodal *** results of optimization of unimodal functions show that the proposed algorithm SSABA has high exploitation power and the results of optimization of multimodal functions show the appropriate exploration power of the proposed *** addition,the performance of the proposed SSABA is compared with the performance of eight well-known algorithms,including Particle Swarm Optimization(PSO),Genetic Algorithm(GA),Teaching-Learning Based Optimization(TLBO),Gravitational Search Algorithm(GSA),Grey Wolf Optimization(GWO),Whale Optimization Algorithm(WOA),Marine Predators Algorithm(MPA),and Tunicate Swarm Algorithm(TSA).The simulation results show that the proposed SSABA is better and more competitive than the eight compared algorithms with better performance.

关键词： Optimization population-based optimization problem search step optimization algorithm minimization maximization

A comprehensive review of the influence of physicochemical properties of biodiesel on combustion characteristics,engine performance and emissions

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Journal of Traffic and Transportation Engineering(English Edition) 2021年第4期8卷 510-533页

作者： Tikendra Nath Verma Pankaj Shrivastava Upendra Rajak gaurav Dwivedi Siddharth Jain Ali Zare Anoop Kumar Shukla Puneet Verma Department of Mechanical Engineering Maulana Azad National Institute of Technology(MANIT)Bhopal 462007India Department of Mechanical Engineering Prestige Institute of Engineering Management and ResearchIndore 452010India Department of Mechanical Engineering Rajeev Gandhi Memorial College of Engineering and TechnologyNandyal 518501India Energy Centre Maulana Azad National Institute of Technology(MANIT)Bhopal 462007India Department of Mechanical Engineering College of Engineering Roorkee(COER)Roorkee 247667India Flow Aerosols and Thermal Energy(FATE)Research GroupSchool of EngineeringDeakin UniversityBurwoodVIC 3216Australia Department of Mechanical Engineering Amity UniversityNoida 201313India School of Chemistry Physics and Mechanical EngineeringQueensland University of TechnologyBrisbaneQLD 4001Australia

Energy is a basic requirement for development in the *** continuously rising demand for energy resources and the fast depletion of fossil fuel is raises researcher's concern to focus on alternative sources of energy that can replace the shortage of fossil fuels *** is recognized as one of the potential alternative renewable energy fuels that can be easily available in a wide range in every part of the *** paper reviews biodiesel's prospect and focuses on the different fuel properties(physicochemical)of 100 biodiesels from first-,second-and third-generation followed by the evaluation of CI engine *** has been observed that the fuel properties of first-,second-and third-generation biodiesel are compatible with the ASTM *** present paper discussed the potential of various generations of biodiesel feedstocks from production *** paper also examined many aspects of these feedstocks which include different biodiesel feedstock sources,biodiesel conversion technology,and second-generation biodiesel performance and emission *** of the studies showed that biodiesel derived from plant feedstock is costly than ***,more influence is to be given to non-edible ***,the engine characteristics are shown promising behavior with biodiesel and a slight increase in NOX is also reported on using various biodiesel.

关键词： Biodiesel Physicochemical Combustion Ignition Emission

Targeting angiogenesis for fracture nonunion treatment in inflammatory disease

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Bone Research 2021年第3期9卷 336-348页

作者： Cuicui Wang Jun Ying Xiaolei Nie Tianhong Zhou Ding Xiao gaurav Swarnkar Yousef Abu-Amer Jianjun Guan Jie Shen Department of Orthopaedic Surgery School of MedicineWashington UniversitySt.LouisMOUSA Department of Orthopaedic Surgery the First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhouChina Institute of Orthopaedics and Traumatology the First Affiliated Hospital of Zhejiang Chinese Medical UniversityHangzhouChina Department of Mechanical Engineering&Materials Science School of EngineeringWashington UniversitySt.LouisMOUSA Shriners Hospital for Children St.LouisMOUSA

Atrophic fracture nonunion poses a significant clinical problem with limited therapeutic *** this study,we developed a unique nonunion model with high clinical relevance using serum transfer-induced rheumatoid arthritis(RA).Arthritic mice displayed fracture nonunion with the absence of fracture callus,diminished angiogenesis and fibrotic scar tissue formation leading to the failure of biomechanical properties,representing the major manifestations of atrophic nonunion in the ***,we demonstrated that the angiogenesis defect observed in RA mice was due to the downregulation of SPP1 and CXCL12 in chondrocytes,as evidenced by the restoration of angiogenesis upon SPP1 and CXCL12 treatment in *** this regard,we developed a biodegradable scaffold loaded with SPP1 and CXCL12,which displayed a beneficial effect on angiogenesis and fracture repair in mice despite the presence of ***,these findings strongly suggest that the sustained release of SPP1 and CXCL12 represents an effective therapeutic approach to treat impaired angiogenesis and fracture nonunion under inflammatory conditions.

关键词： CXCL12 angiogenesis impaired