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Clinicopathological Correlation of Primary Malignant Bone Tumors—An Observational Study

Open Journal of Orthopedics 2015年第4期5卷 100-108页

作者： Palash Bhattacharya anadi roy chowdhury Bhaskar Mitra Biswanath Paul Department of Pathology N.R.S.M.C.H. Kolkata India Drs Tribedi & roy Diagnostic Laboratory Kolkata West-Bengal India Department of Pathology Midnapore Medical College & Hospital Paschim Medinipur West-Bengal India

Background: Primary malignant tumors arising from bone are uncommon but important malignant neoplasms which account for 0.2% of all primary cancers in adults and approximately 5% of all childhood malignancies. Aim: No comprehensive surveillance data about primary malignant bone tumors is available from this region of West Bengal in the literature. An attempt is undertaken to correlate clinicopathological findings, both histological & cytological features of primary bone tumours. Method: This observational study of clinical presentation was corroborated with cytology and histopathology of 67 cases of primary malignant bone tumors in 2005-2007 in a tertiary health care centre. Results: Among the primary malignant tumors, 39 cases (58.20%) were male and 28 (41.80%) were female. Sixty one lesions (91%) were located in the long bones and 6 (9%) involving flat and short bones. Osteosarcomas are found to be the predominant primary malignant bone tumors (44.77%), followed by Ewing’s sarcomas (20.89%), chondrosarcomas (13.43%), high grade giant cell tumor, and plasmacytoma (5.97%). Predilection for male (M: F 2:1) found in both osteosarcoma and chondrosarcoma, but it was reverse in cases of Ewing’s sarcomas. Conclusion: Osteosarcoma is the most common around knee joint and chondrosarcoma is frequent in long bones in this region. We made an attempt to correlate FNAC findings with the histopathology and it was seen that overall sensitivity of FNAC of primary malignant bone tumors was 56.71%.

关键词： Primary Malignant Bone Tumor Clinicopathological Study

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Rare Occurrence of Primary Chest Wall Bone Tumours

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Open Journal of Orthopedics 2012年第4期2卷 138-143页

作者： Bhaskar Mitra anadi roy Choudhury Palash Bhattacharya Biswanath Paul Department of Pathology Midnapore Medical College & Hospital Paschim Medinipur India Department of Pathology RG Kar Medical College & Hospital Kolkata India.

Primary tumors involving the bony skeleton of the chest wall are uncommon. After a retrospective review of the histopathology archive at our institution from Oct 08 to Mar 09 we found three malignant neoplasms affecting the rib, clavicle and the costal cartilages, one mesenchymal chondrosarcoma, one case of clear cell chondrosarcoma and an aggressive osteoblastoma each having distinctive histological diagnosis. Our limited experience in the occurrence of primary chest wall tumors showed that there are occurrences of rare bony lesions. A strong clinical suspicion, clinico-radiological correlation and histopathological confirmation are required for proper evaluation.

关键词： Primary Chest Wall Tumours Mesenchymal Chondrosarcoma Clear Cell Chondrosarcoma Aggressive Osteoblastoma

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Rare Occurrence of Primary Chest Wall Bone Tumours

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Open Journal of Orthopedics（矫形学期刊） 2012年第4期

作者： Bhaskar Mitra anadi roy Choudhury Palash Bhattacharya Biswanath Paul

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