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Journal of Animal Science and Biotechnology 2021年第3期12卷 1112-1124页

作者： Sandra J.A.van Kuijk Yanming Han ana Isabel Garcia-ruiz ana Rodiles Trouw Nutrition R&D P.O.Box 2993800AGAmersfoortthe Netherlands Trouw Nutrition R&D 45950 Casarrubios del MonteToledoSpain.

Background:The objective was to study the effect of hydroxychloride trace minerals(HTM)on growth performance,carcass quality and gut microbiota of broiler chickens in comparison to sulphate trace minerals(STM).In total 1440 male Ross 308 day-old chicks were divided into 12 replicate pens with 30 birds each per *** different treatments were tested according to a 2×2 factorial study design,where the animals received a three phase diet containing either inorganic Zn from sulphates or Zn from HTM in high(80 mg/kg Zn)or low Zn dosage(20 mg/kg Zn).In all treatments 15 mg/kg Cu was added from the same mineral source as the *** weight and feed intake were measured on day 0,10,27 and 34,while carcass and breast meat yields were measured at the end of the study(day 34).In addition,high-throughput sequencing analysis was performed in digesta samples from ileum and cecum to study the gut microbiome(day 34).Results:The results showed an improved(Panalysis of the microbiota revealed a higher microbial diversity in the ileum and cecum of HTM fed birds compared to STM fed *** differences were mainly found in the cecum,specifically between the group fed high and low Zn levels from *** correlated with the mineral contents observed in the cecal *** both groups fed 80 mg/kg Zn,the HTM group had more Streptococcaceae,Streptococcus,Clostridia,Weissella and Leuconostocaceae compared to the STM ***:HTM improved growth performance of broiler chickens;and th

关键词： Broiler chickens Growth performance Gut microbiota Hydroxychloride trace minerals

Effect of Lepidium meyenii(maca)roots on spermatogenesis of male rats

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Asian Journal of Andrology 2001年第3期3卷 231-233页

作者： Gustavo F.Gonzales ana ruiz Carla Gonzales León Villegas Amanda Cordova Department of Physiological Sciences Faculty of Sciences and Philosophy and Instituto de Investigaciones de la Altura.Universidad Peruana Cayetano Heredia.Postal Office 1843.LimaPeru

Aim:To determine the effect of oral administration of an aqueous extract from the roots of Lepidium meyenii(maca)on spermatogenesis in adult male ***;Male rats received an aqueous extract of the root(66.7 mg in onemL)twice a day for 14 consecutive ***:Treatment with Lepidium meyenii resulted in an increase in theweights of testis and epididymis but not the seminal vesicle *** length and frequency of stages IX-XIV seminif-erous tubules,where mitosis occurred,were increased and stages I-VI were reduced in rats treated with ***;The Lepidium meyenii root invigorates spermatogenesis in male rats by acting on its initialstages(IX-XIV).

关键词： spermatogenesis Lepidium meyenii maca transillumination

A long-term record of land use change impacts on sediments in Oualidia lagoon,Morocco

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International Journal of Sediment Research 2014年第1期29卷 1-10页

作者： Mehdi MAanaN ana Carolina ruiz-FERNNDEZ Mohamed MAanaN Paul FATTAL Bendahhou ZOURARAH Mohamed SAHABI Géolittomer UMR 6554 LETG Université de Nantes Marine Geosciences Laboratory URAC 45Earth Sciences departmentFaculty of Sciences Universidad Nacional Autónoma de México.Instituto de Ciencias del Mary Limnología

An integrated approach,involving land use patterns and heavy metal contents of the surficial and cored sediment,was proposed to detect the characteristic spatial and temporal scale of point and non-point source human disturbances on the Oualidia lagoon in *** and description of the temporal and spatial distributions of the main contamination sources of heavy metals are analyzed using statistics and GIS *** results show that surficial sediments are highly enriched in heavy metals compared to their preindustrial background ***-use types affected lagoon sediment pollution in different ways:1) agricultural areas had the highest potential for sediment contamination by heavy metals,particularly Pb,Cu and Hg,2) Ni and Cr are the main pollutants originating from urban sewage and 3) oyster farming and traditional land uses such as salt flats,pastures showed low levels of others *** enrichment factors(normalized by Al) obtained from the sediment cores indicated that the lagoon is(strongly/moderately) polluted by all metals which were attributed to agricultural activities and wastewater discharges from urbanized areas.

关键词： Land use change(LUC) Geographical information systems(GIS) Sediment pollution Risk assessment

Roles of Ubiquitination in the Control of Phosphate Starvation Responses in Plants

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Journal of Integrative Plant Biology 2013年第1期55卷 40-53页

作者： Mónica Rojas-Triana Regla Bustos ana Espinosa-ruiz Salom Prat Javier Paz-Ares Vicente Rubio The Samuel Roberts Noble Foundation Department of Plant Biology 2510 Sam Noble Parkway Ardmore CBGP (INIA-UPM) Departamento de Biotecnología Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Campus de Montegancedo Centro Nacional de Biotecnología (CNB-CSIC) Darwin

Throughout evolution, plants have evolved sophisticated adaptive responses that allow them to grow with a limited supply of phos-phate, the preferential form in which the essential macronutrient phosphorus is absorbed by plants. Most of these responses are aimed to increase phosphate availability and acquisition through the roots, to optimize its usage in metabolic processes, and to protect plants from the deleterious effects of phosphate deficiency stress. Regulation of these adaptive responses requires fine percep- tion of the external and internal phosphate levels, and a complex signal transduction pathway that integrates information on the phosphate status at the whole-plant scale. The molecular mecha-nisms that participate in phosphate homeostasis include transcriptional control of gene expression, RNA silencing mediated by microRNAs, regulatory non-coding RNAs of miRNA activity, phosphate transporter trafficking, and post-translational modification of proteins, such as phosphorylation, sumoylation and ubiquitination. Such a varied regulatory repertoire reflects the complexity intrinsic to phosphate surveying and signaling pathways. Here, we describe these regulatory mechanisms, emphasizing the increasing importance of ubiquitination in the control of phosphate starvation responses.

关键词： Phosphate homeostasis phosphate signaling phosphate starvation post-translational control ubiquitin.

Exercise and quality of life in cancer

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Journal of Sport and Health Science 2023年第4期12卷 489-490页

作者： Carmen Fiuza-Luces Pedro L.Valenzuela Alejandro Santos-Lozano ana ruiz-Casado Alejandro Lucia Physical Activity and Health Research Group(PaHerg) Research Institute of Hospital 12 de Octubre(‘i+12’)Madrid 28041Spain Department of Systems Biology University of AlcalaMadrid 28871Spain i+HeALTH Research Group Department of Health SciencesEuropean University Miguel de CervantesValladolid 47012Spain Department of Medical Oncology Hospital Universitario Puerta de Hierro MajadahondaInstituto de Investigacion Sanitaria Puerta de Hierro-Segovia de Arana(IDIPHISA)Madrid 28220Spain Faculty of Sport Sciences Universidad Europea de MadridMadrid 28670Spain

Historically,patients with cancer were told to avoid physical *** dogma has changed over the last 2 decades,with an exponential growth in the number of studies showing not only the safety,but also the benefits of regular physical activity/exercise in the cancer continuum,notably for attenuating treatment-related toxicities and side effects.

关键词： cancer patients showing

Mineralogical signatures and sources of recent sediment in a large tropical lake

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International Journal of Sediment Research 2018年第2期33卷 183-190页

作者： Jorge Feliciano Ontiveros-Cuadras ana Carolina ruiz-Fernández Joan-Albert Sanchez-Cabeza Libia Hascibe Pérez-Bernal Michel Preda Federico Páez-Osuna Polytechnic University of Sinaloa (UPSIN) Mazatlan Academic Unit Institute of Marine Sciences and LimnologyNational Autonomous University of Mexico (UNAM) Oceanic and Coastal Processes Academic Unit Institute of Marine Sciences and LimnologyNational Autonomous University of Mexico (UNAM).University City Department of Earth and Atmospheric Sciences University of Quebec in Montreal (UQAM)

Two lead-210(210Pb) dated sediment cores from Chapala Lake were studied to identify the mineral composition of the sediments and to discuss its relation with trace metals. Minerals and trace metals reflected the domain of volcanic rocks(i.e. basalts, rhyolite and andesite) that characterize Chapala Lake and the Lerma River watershed. Redundancy analyses(RDA) were used to identify the sedimentary variables(magnetic susceptibility, organic matter, sand content, and mineral composition) that could be related to elemental composition. Despite the distance between the two cores(7.3 km) and hydrodynamic circulation the RDA showed that the main mechanism that controls the input of mineral species,and, therefore, element distributions in the lacustrine sediment of Chapala Lake, is related to the weathering of volcanic rocks in the Lerma-Chapala watershed, the consequent runoff and transport of fine grained catchment materials, and later in-lake processes. These findings highlight the importance of controlling watershed erosion to contribute to the improvement of the environmental quality of the lake.

关键词： Chapala Lake Trace metals Mineralogy Lacustrine sediments

Global longitudinal strain is superior to ejection fraction for detecting myocardial dysfunction in end-stage renal disease with hyperparathyroidism

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World Journal of Cardiology 2022年第4期14卷 239-249页

作者： Maria Fernanda Carrasco-ruiz Antonio ruiz-Rivera Marvin A Soriano-Ursúa Carlos Martinez-Hernandez Leticia Manuel-Apolinar Carmen Castillo-Hernandez Gustavo Guevara-Balcazar Eunice D Farfán-García ana Mejia-ruiz Ivan Rubio-Gayosso Teresa Perez-Capistran Department of Physiology Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Department of Cardiology Instituto Mexicano del Seguro SocialCiudad de México 06720Mexico Endocrine Research Unit Instituto Mexicano del Seguro SocialCiudad de México 06720Mexico Department of Cardiovascular Pharmacology Instituto Politécnico NacionalCiudad de México 11340Mexico Department of Biochemistry Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Education Research Comisión Nacional Para la Mejora Continua de la EducaciónCiudad de México 03900Mexico Postgraduate Studies and Research Section Escuela Superior de MedicinaInstituto Politécnico NacionalCiudad de México 11340Mexico Department of Physiology Instituto Politécnico NacionalMexico City 11340Ciudad de MéxicoMexico

BACKGROUND The estimation of left ventricular ejection fraction(LVEF)by 2D echocardiography(2D-ECHO)is the most used tool to assess LV systolic function(LVSF).Global longitudinal strain(GLS)has recently been suggested as a superior method for several *** study explored the association and prevalence of LV systolic dysfunction(LVSD)by using these methods in patients with end-stage renal disease(ESRD)and severe hyperparathyroidism(SHPTH);both associated with cardiovascular events(CEs).AIM To evaluate the myocardial function in patients with ESRD and SHPTH by using the GLS and LVEF measured through conventional *** In 62 patients with ESRD and SHPTH,asymptomatic,and without a history of CEs,LVSF was evaluated by 2D-ECHO,obtaining the EF,by the Simpson biplane method,and GLS by speckle *** The total patients with ESRD had a preserved LVEF(>50%)but abnormal GLS(analysis showed an independent association of GLS and serum parathyroid hormone(PTH),LV mass index,and ***,PTH was independently associated with lateral e'wave and tricuspid regurgitation *** In patients with SHPTH linked to ESRD,the use of GLS by 2D-ECHO is a more sensitive tool than LVEF for detecting LVSD.

关键词： Left ventricular hypertrophy Systolic dysfunction Global longitudinal strain End-stage renal disease Parathormone

Functional mechanism study of the allelochemical myrigalone A identifies a group of ultrapotent inhibitors of ethylene biosynthesis in plants

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Plant Communications 2024年第6期5卷 246-262页

作者： George Heslop-Harrison Kazumi Nakabayashi ana Espinosa-ruiz Francesca Robertson Robert Baines Christopher R.L.Thompson Katrin Hermann David Alabadí Gerhard Leubner-Metzger Robin S.B.Williams Centre for Biomedical Sciences Department of Biological SciencesRoyal Holloway University of LondonEgham TW200EXUK Centre for Plant Molecular Sciences Department of Biological SciencesRoyal Holloway University of LondonEgham TW200EXUK Instituto de Biología Molecular y Celular de Plantas(CSIC-UPV) 46022 ValenciaSpain Centre for Life’s Origins and Evolution Department of GeneticsEvolution and EnvironmentUniversity College LondonLondonUK Syngenta Crop Protection AGSteinSwitzerland

Allelochemicals represent a class of natural products released by plants as root,leaf,and fruit exudates that interfere with the growth and survival of neighboring *** how allelochemicals function to regulate plant responses may provide valuable new approaches to better control plant *** such allelochemical,Myrigalone A(MyA)produced by Myrica gale,inhibits seed germination and seedling growth through an unknown ***,we investigate MyA using the tractable modelDictyostelium discoideum and reveal that its activity depends on the conserved homolog of the plant ethylenesynthesis protein 1-aminocyclopropane-1-carboxylic acid oxidase(ACO).Furthermore,in silico modeling predicts the direct binding of MyA to ACO within the catalytic *** ***,ablation of ACO mimics the MyA-dependent developmental delay,which is partially restored by exogenous ethylene,and MyA reduces ethylene *** Arabidopsis thaliana,MyA treatment delays seed germination,and this effect is rescued by exogenous *** also mimics the effect of established ACO inhibitors on root and hypocotyl extension,blocks ethylenedependent root hair production,and reduces ethylene ***,in silico binding analyses identify a rangeof highlypotentethylene inhibitorsthatblock ethylene-dependent responseand reduce ethyleneproduction in ***,we demonstrate a molecular mechanism by which the allelochemical MyA reduces ethylene biosynthesis and identify a range of ultrapotent inhibitors of ethylene-regulated responses.

关键词： 1-aminocyclopropane-1-carboxylic acid ACC ACC oxidase ACO allelochemicals ethylene synthesis inhibitors structure-activity relationship

Using the polymerase chain reaction coupled with denaturing gradient gel electrophoresis to investigate the association between bacterial translocation and systemic inflammatory response syndrome in predicted acute severe pancreatitis

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World Journal of Gastroenterology 2005年第45期11卷 7142-7147页

作者： Callum B Pearce Vitaly Zinkevich Iwona Beech Viera Funjika ana Garcia ruiz Afraa Aladawi Hamish D Duncan Queen Alexandra Hospital Microbiology Research Laboratory

AIM: To investigate the use of PCR and DGGE to investigate the association between bacterial translocation and systemic inflammatory response syndrome in predicted severe ***: Patients with biochemical and clinical evidence of acute pancreatitis and an APACHE Ⅱ score ≥8 were enrolled. PCR and DGGE were employed to detect bacterial translocation in blood samples collected on d1,3, and 8 after the admission. Standard microbial blood cultures were taken when there was clinical evidence of sepsis or when felt to be clinically indicated by the supervising ***: Six patients were included. Of all the patients investigated, only one developed septic complications;the others had uneventful illness. Bacteria were detected using PCR in 4 of the 17 collected blood samples. The patient with sepsis was PCR-positive in two samples (taken on d 1 and 3), despite three negative blood cultures. Using DGGE and specific primers, the bacteria in all blood specimens which tested positive for the presence of bacterial DNA were identified as E ***: Our study confirmed thatunlike traditional microbiological techniques, PCR can detect the presence of bacteria in the blood of patients with severe AP. Therefore, this latter method in conjunction with DGGE is potentially an extremely useful tool in predicting septic morbidity and evaluating patients with the disease. Further research using increased numbers of patients, in particular those patients with necrosis and sepsis, is required to assess the reliability of PCR and DGGE in the rapid diagnosis of infection in AP.

关键词： Polymerase chain reaction Acutepancreatitis Bacterial translocation

Modelling fuel loads of understorey vegetation and forest floor components in pine stands in NW Spain

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Forest Ecosystems 2022年第6期9卷 775-789页

作者： Jose A.Vega Stefano Arellano-Perez Juan Gabriel Alvarez-Gonzalez Cristina Fernandez Enrique Jimenez Pedro Cuinas Jose María Fernandez-Alonso Daniel J.Vega-Nieva Fernando Castedo-Dorado Cecilia Alonso-Rego Teresa Fontúrbel ana Daría ruiz-Gonzalez Centro de Investigacion Forestal de Lourizan PO Box 12736080PontevedraSpain Unidad de Gestion Ambiental y Forestal Sostenible(UXAFORES) Departamento de Ingeniería AgroforestalEscuela Politecnica Superior de IngenieríaUniversidad de Santiago de CompostelaCampus Universitario s/n27002LugoSpain Facultad de Ciencias Forestales Universidad Juarez del Estado de DurangoRío Papaloapan y Blvd.Durango s/nCol.Valle del Sur34120DurangoMexico Departamento de Ingeniería y Ciencias Agrarias Universidad de LeonCampus de Ponferrada24401PonferradaSpain

In this study,310 destructively sampled plots were used to develop two equation systems for the three main pine species in NW Spain(***;*** and ***):one for estimating loads of understorey fuel components by size and condition(live and dead)and another one for forest floor *** systems of equations were simultaneously fitted for estimating fuel loads using overstorey,understorey and forest floor variables as *** systems of equations included both the effect of pine species and the effect of understorey compositions dominated by ferns-brambles or by woody species,due to their obvious structural and physiological *** general,the goodness-of-fit statistics indicated that the estimates were reasonably robust and accurate for all of the fuel *** best results were obtained for total understorey vegetation,total forest floor and raw humus fuel loads,with more than 76%of the observed variability explained,whereas the poorest results were obtained for coarse fuel loads of understory vegetation with a 53%of observed variability *** reduce the overall costs associated with the field inventories necessary for operational use of the models,the additive systems were fitted again using only overstorey variables as potential *** relationships for fine(<6 mm)and total understorey vegetation and total forest floor fuel loads were obtained,indicating the complexity of the forest overstorey-understorey and overstorey-forest floor ***,these models explained around 52%of the observed ***,equations estimating the total understorey vegetation and the total forest floor fuel loads based only on canopy cover were *** models explained only 26%-32%of the observed variability;however,their main advantage is that although understorey vegetation in forested landscapes is largely invisible to remote sensing,canopy cover can be estimated with moderate accuracy,allowin

关键词： Area-based approach Additive equation systems Live and dead fine fuel Pinus pinaster Pinus radiata Pinus sylvestris