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Biodiversity responses to insular fragmentation in Amazonia: Two decades of research in the Balbina Hydroelectric Reservoir

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Zoological Research(Diversity and Conservation) 2024年第2期1卷 106-116页

作者： ana Filipa Palmeirim maíra Benchimol Danielle Storck-Tonon Anderson S.Bueno Isabel L.Jones Gilmar Klein Carlos A.Peres CIBIO Research Centre of Biodiversity and Genetic ResourcesInBIO Associated LabVairão CampusUniversity of PortoVairão 4485-661Portugal BIOPOLIS Program in Genomics Biodiversity and Land PlanningCIBIOVairão CampusUniversity of PortoVairão 4485-661Portugal Laboratório de Ecologia AplicadaàConservação Universidade Estadual de Santa CruzIlhéusBahia 45662-900Brazil Programa de Pós-Graduação em Ambiente e Sistemas de Produção Agrícola(PPGASP) Universidade do Estado de Mato GrossoTangaráda SerraMato Grosso 78301-532Brazil Instituto Federal de Educação Ciência e Tecnologia FarroupilhaJúlio de CastilhosRio Grande do Sul 98130-000Brazil Biological and Environmental Sciences University of StirlingStirling FK94LAUK REBIO Uatumã/ICmBio Presidente FigueiredoAmazonas 69736-000Brazil Centre for Ecology Evolution and ConservationSchool of Environmental SciencesUniversity of East AngliaNorwich NR47TJUK JuruáInstitute ManausAmazonas 69057-060Brazil

As hydropower development expands across lowland tropical forests,flooding and concomitant insular fragmentation have become important threats to *** created insular landscapes serve as natural laboratories to investigate biodiversity responses to *** of these most iconic landscapes is the Balbina Hydroelectric Reservoir in Brazilian Amazonia,occupying>400000 ha and comprising>3500 forest ***,we synthesise the current knowledge on responses of a wide range of biological groups to insular fragmentation at *** has largely concentrated on a set of 22 islands and three mainland *** total,39 studies were conducted over nearly two decades,covering 17 vertebrate,invertebrate,and plant *** species responses varied according to taxonomic group,island area was consistently included and played a pivotal role in 66.7%of all studies examining patterns of species *** persistence was further affected by species traits,mostly related to species capacity to use/traverse the aquatic matrix or tolerate habitat degradation,as noted for species of vertebrates and orchid *** research is needed to improve our understanding of such effects on wider ecosystem *** Impact Assessments must account for changes in both the remaining habitat amount and configuration,and subsequent long-term species losses.

关键词： Habitat loss Hydropower dams Landbridge Local extinctions Species-area relationships Species diversity Tropical forests

Neuroendocrine gastric carcinoma expressing somatostatin: A highly malignant, rare tumor

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World Journal of Gastroenterology 2006年第24期12卷 3944-3947页

作者： Jaques Waisberg Leandro Luongo de matos ana maria do Amaral Antonio mader Sérgio Pezzolo Esmeralda miristene Eher Vera luiza Capelozzi manlio Basilio Speranzini Department of Surgery Faculty of medicine of ABC Santo AndréBrazil Faculty of medicine of ABC Santo André S(a|~)o PauloBrazil Department of Pathology Faculty of medicine of ABC Santo AndréBrazil Department of Pathology Faculty of medicine S(a|~)o Paulo UniversityBrazil

Poorly differentiated gastric neuroendocrine carcinomas, although rare, deserve particular attention, as they are aggressive and have an extremely poor prognosis. In this report we describe a gastric neuroendocrine carcinoma with rapidly fatal outcome. Immunohistological staining of the resected specimens revealed that the tumor was an endocrine carcinoma. The tumor disclosed intense immunoreactivity to pan-neuroendocrine markers and diffuse somatostatin immunoreactivity. There were no psammoma bodies and no demonstrable association with yon Recklinghausen＇s neurofibromatosis. In the gastrointestinal tract, neuroendocrine tumors producing predominantly somatostatin have been described only in the duodenum. To the best of our knowledge, the present report is the second case report of a neuroendocrine gastric carcinoma expressing diffusely somatostatin as the only neuroendocrine regulatory peptide.

关键词： Neuroendocrine carcinoma Neuroendocrinetumors Carcinoid Stomach neoplasms Somatostatin Immunohistochemistry Tumor markers Enterochromaffin-like cells

A Statistical analysis of Textual E-Commerce Reviews Using Tree-Based methods

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Open Journal of Statistics 2022年第3期12卷 357-372页

作者： Jessica Kubrusly ana luiza Neves Thamires Louzada marques Department of Statistics Universidade Federal Fluminense Niterói Brazil

With the increasing interest in e-commerce shopping, customer reviews have become one of the most important elements that determine customer satisfaction regarding products. This demonstrates the importance of working with Text mining. This study is based on The Women’s Clothing E-Commerce Reviews database, which consists of reviews written by real customers. The aim of this paper is to conduct a Text mining approach on a set of customer reviews. Each review was classified as either a positive or negative review by employing a classification method. Four tree-based methods were applied to solve the classification problem, namely Classification Tree, Random Forest, Gradient Boosting and XGBoost. The dataset was categorized into training and test sets. The results indicate that the Random Forest method displays an overfitting, XGBoost displays an overfitting if the number of trees is too high, Classification Tree is good at detecting negative reviews and bad at detecting positive reviews and the Gradient Boosting shows stable values and quality measures above 77% for the test dataset. A consensus between the applied methods is noted for important classification terms.

关键词： Text mining Supervised Classification Tree-Based methods Classification Trees Random Forest Gradient Boosting XGBoost

Impact of tropospheric modelling on GNSS vertical precision:an empirical analysis based on a local active network

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International Journal of Digital Earth 2018年第9期11卷 880-896页

作者： mªSelmira Garrido mªClara de Lacy ana mªRojas Department of Cartographic Geodetic and Photogrammetric EngineeringUniversity of JaénJaenSpain Center for Advanced Studies in Earth Sciences University of JaénJaenSpain Research group RNm282–microgeodesia Jaén University of JaénJaenSpain

The troposphere affects Global Navigation Satellite System(GNSS)signals due to the variability of the refractive *** delay is a function of the satellite elevation angle and the altitude of the GNSS receiver and depends on the atmospheric *** the residual tropospheric delay is not modelled carefully a bias error will occur in the vertical *** order to analyse the precise altimetric positioning based on a local active network,four scenarios in Southern Spain with different topographical,environmental,and meteorological conditions are presented,considering both favourable and non-favourable *** use of surface meteorological observations allows us to take into account the tropospheric conditions instead of a standard atmosphere,but introduces a residual tropospheric bias which reduces the accuracy of precise GNSS ***,with short observation times it is recommended not to estimate troposphere parameters,but to use an a priori model together with the standard *** results confirm that it is possible to achieve centimetre-scale vertical accuracy and precision with real time kinematic positioning even with large elevation differences with respect to the nearest reference *** numerical results may be taken into consideration for improving the altimetric configuration of the local active network.

关键词： Altimetry GNSS meteorological data active network tropospheric refraction

High aluminum concentration and initial establishment of Handroanthus impetiginosus : clues about an Al non-resistant species in Brazilian Cerrado

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Journal of Forestry Research 2020年第6期31卷 2075-2082页

作者： Ane marcela das Chagas mendon ca Jean marcel Sousa Lira ana luiza de Oliveira Vilela Daniel Amorim Vieira Nayara Cristina de melo Joao Paulo Rodrigues Alves Delfi no Barbosa Programa de Pós-Graduacao em Fisiologia Vegetal Departamento de BiologiaUniversidade Federal de LavrasLavrasMG 37200-000Brazil Programa de Pós-Graduacao em Ciências Ambientais Instituto de Ciências ExatasUniversidade Federal de AlfenasAlfenasMG 37130-001Brazil Programa de Pós-Graduacao em Fitotecnia Departamento de AgriculturaUniversidade Federal de LavrasLavrasMG 37200-000Brazil Instituto Federal de Educacao Ciência e Tecnologia do Pará BelémPA 66093-020Brazil

Cerrado soils are acidic and nutrient-poor,with high content of solubilized Al 3+.Plants growing in these conditions may display adaptations to cope with high aluminum concentrations especially during early developmental *** investigated leaf nutritional status,and photosynthetic and growth characteristics during the initial establishment of Handroanthus impetiginosus(*** Dc.)mattos,a secondary tree species distributed in the Brazilian *** goal was to understand leaf-level traits related to diff erent aluminum *** plants were cultivated in four diff erent aluminum sulfate concentrations:0,1,2,and 4 mm Al,for 40 *** performed analyses of growth,leaf gas exchange,chloroplast pigment content,and leaf mineral *** observed a linear increase of Al leaf content as a function of Al concentration in the nutrient *** grown in 1 mm Al showed a remarkable increase of K leaf content,net photosynthesis,stomatal conductance,and transpiration,while in 4 mm Al there were reductions of N,P,and K contents,gas exchange characteristics,and *** did not have mechanisms of avoidance,compartmentalization,or resistance to high Al ***,this species showed a hormetic response,with low Al concentrations stimulating and high Al concentrations inhibiting plant responses.

关键词： Hormesis Low Al concentration Al toxicity Cerrado species Carbon assimilation

The Influence of High Temperature Exposure on the Wear Performance of a Ni Based Alloy PTA Coating

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材料热处理学报 2004年第5期25卷 152-156页

作者： Karin Graf ana Sofia C.m. d'OIiveira mechanical Department of Universidade Federal do Parana Curitiba BrazilMechanical Department of Universidade Federal do Parana Curitiba Brazil

Degradation phenomena like wear and corrosion, may have their effects accelerated as components operate at high temperature. The aim of this work is to make an indirect evaluation of the influence of high temperature exposure on wear behavior of Ni coatings. A Ni-Cr-mo-W alloy, was deposited with Plasma Transferred Arc (PTA) process. An indirect approach based on the Ahrrenius relationship was used to evaluated long time exposures at high temperatures. To simulate longer exposures at lower temperatures, coatings were exposed to higher temperatures for the same time interval. So coatings were soaked in an air furnace at 650°C, 1000°C and 1200°C. metal/metal wear behavior was evaluated by pin-on-disc tests. Pins were removed from the coatings by eletrodischarge machining and rubbed against a VC31 quenched and tempered tool steel. Two sets of wear tests were run at 2m/s, for different loads (0.5, 1.0, 2.0 and 3.0Kg) and for different sliding distances (120, 720, 1080, 1440 and 1800m).Coatings characterization was done by scanning electronic microscopy and Vickers microhardness. Results showed as temperature is increased, coatings wear performance is altered, and this is associated with microstructural changes.

关键词：磨损 Ni合金 PTA 高温曝露

Therapeutic Properties of Flavonoids in Treatment of Cancer through Autophagic modulation:A Systematic Review

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Chinese Journal of Integrative medicine 2023年第3期29卷 268-279页

作者： Guilherme Vinicio de Sousa Silva ana luiza Vieira Ferreira Guimaraes Lopes Isis Carolina Viali Lucas Zannini medeiros Lima matheus Ribeiro Bizuti Fabiana Brum Haag Débora Tavares de Resende e Silva Department of medicine Federal University of Fronteira SulChapecóSanta CatarinaBrazil Department of Nursing Federal University of Fronteira SulChapecóSanta CatarinaBrazil Department of Graduate Studies in Biomedical Sciences Federal University of Fronteira SulChapecóSanta CatarinaBrazil

Cancers have high morbidity and mortality rates *** anticancer therapies have demonstrated specific signaling pathways as a target in the involvement of *** is a quality control system for proteins and plays a fundamental role in cancer carcinogenesis,exerting an anticarcinogenic role in normal cells and can inhibit the transformation of malignant ***,drugs aimed at autophagy can function as antitumor *** are a class of polyphenolic secondary metabolites commonly found in plants and,consequently,consumed in *** this review,the systematic search strategy was used,which included the search for descriptors"flavonoids"AND"mTOR pathway"AND"cancer"AND"autophagy",in the electronic databases of Pubmed,Cochrane Library,Web of Science and Scopus,from January 2011 to January *** current literature demonstrates that flavonoids have anticarcinogenic properties,including inhibition of cell proliferation,induction of apoptosis,autophagy,necrosis,cell cycle arrest,senescence,impaired cell migration,invasion,tumor angiogenesis and reduced resistance to multiple drugs in tumor *** demonstrate the available evidence on the roles of flavonoids and autophagy in cancer progression and inhibition.(Registration ***42021243071 at PROSPERO)

关键词： anti-cancer effects apoptosis cell proliferation cell survival flavonoids

molecular approaches for spinal cord injury treatment

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Neural Regeneration Research 2023年第1期18卷 23-30页

作者： Fernanda martins de Almeida Suelen Adriani marques Anne Caroline Rodrigues dos Santos Caio Andrade Prins Fellipe Soares dos Santos Cardoso luiza dos Santos Heringer Henrique Rocha mendonça ana maria Blanco martinez Laboratório de Neurodegeneração e Reparo Programa de Pós-Graduação em Medicina:Anatomia PatológicaDepartamento de PatologiaFaculdade de MedicinaHospital Universitário Clementino Fraga FilhoCentro de Ciências da SaúdeUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil Instituto de Ciências Biomédicas Centro de Ciências da SaúdeUniversidade Federal do Rio de JaneiroRio de JaneiroBrazil Instituto de Biologia Departamento de NeurobiologiaLaboratório de Regeneração Neural e FunçãoUFFRio de JaneiroBrazil Laboratório Integrado de morfologia Instituto de Biodiversidade e Sustentabilidade NUPEMPrograma de Pós-graduação Multicêntrico em Ciências Fisiológicas-SBFisCentro Multidisciplinar UFRJ-MacaéUniversidade Federal do Rio de JaneiroMacaéBrazil

Injuries to the spinal cord result in permanent disabilities that limit daily life *** main reasons for these poor outcomes are the limited regenerative capacity of central neurons and the inhibitory milieu that is established upon traumatic *** decades of research,there is still no efficient treatment for spinal cord *** strategies are tested in preclinical studies that focus on ameliorating the functional outcomes after spinal cord *** these,molecular compounds are currently being used for neurological recovery,with promising *** molecules target the axon collapsed growth cone,the inhibitory microenvironment,the survival of neurons and glial cells,and the re-establishment of lost *** this review we focused on molecules that are being used,either in preclinical or clinical studies,to treat spinal cord injuries,such as drugs,growth and neurotrophic factors,enzymes,and *** mechanisms of action of these molecules are discussed,considering traumatic spinal cord injury in rodents and humans.

关键词： axonal regeneration drugs enzymes growth factors molecular therapy neurotrophic factors purines spinal cord injury

Unusual presentation of multiorgan extrapulmonary sarcoidosis

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Rheumatology & Autoimmunity 2024年第1期4卷 62-64页

作者： ana Lilia Peralta Amaro Tania Stefanía Cabrera Castillo maría de losÁngeles macias Clavijo Fernando méndez Gallegos Abihai Lucas Hernández Internal medicine Department Hospital de Especialidades“Dr.Antonio Fraga Mouret”Centro Médico Nacional La RazaInstituto Mexicano del Seguro SocialCiudad de MéxicoMéxico Departamento de Estudios de Posgrado Universidad Nacional Autónoma de México(UNAM)Ciudad de MéxicoMéxico Pathological anatomy Department Hospital de Especialidades“Dr.Antonio Fraga Mouret”Centro Médico Nacional La RazaInstituto Mexicano del Seguro SocialCiudad de MéxicoMéxico

To the Editor,Sarcoidosis is a disease known for over a century and remains enigmatic in etiology and pathophysiology.1 While the pulmonary manifestation prevails in more than 90%of cases,sarcoidosis can affect any ***,it targets the eyes,skin,lymph nodes,and,in rare instances,the liver and spleen.2 The development of the disease is significantly influenced by genetic and environmental factors,as well as gene variations on chromosome ***,first-degree relatives of patients have a heightened risk factor of *** adverse prognostic factors involve being of Black race,female gender,and having a lower *** increased incidence of sarcoidosis among firefighters who responded to the 9/11 disaster highlighted environmental triggers,including agricultural employment,metalworking,firefighting,exposure to inorganic and silica dust,and handling building supplies.1 Clinical symptoms can vary widely depending on the affected *** often relies on characteristic chest radiography findings,but approximately 10%of patients show noncaseating granulomas on biopsy without pulmonary abnormalities.2 Herein,we present a unique case of multiorgan sarcoidosis,where the sole manifestations were severe thrombocytopenia,weight loss,and a history of cerebral vascular events.

关键词： sarcoidosis spleen disaster