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analysis of the Risks of Development Injury Related to Surgical Positioning in a University Hospital of the State of Goiás/Brazil: An Observational-Epidemiological Study

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Health 2020年第7期12卷 876-890页

作者： Bárbara Almeida Lemes Barbara Correia Neves Sabino Carlos Eduardo Carvalho Sabino ana clara Lenza Martins ana Letícia Neller Finta André Vinícius de Oliveira Mariana Cordeiro Carvalho Carolina Veras Mendes Giulia Ugucioni Garbelini Lara Cândida de Sousa Machado Idiberto José Zotarelli Filho Rio Verde University—UniRv Rio Verde Goiás Brazil Faculty of Medical Sciences State University of Campinas—UNICAMP Campinas Brazil Southwest Emergency Hospital—HURSO Brazil Faceres Medical School of Sã o José do Rio Preto/SP Brazil

Introduction: The perioperative nurse plays an important role throughout the surgical period, especially in the context of predicting the risks to which patients are exposed when entering a surgical center. These can be skin, muscle, tendon, and even burn injuries from the scalpel or chemicals. Objective: The aim of this study was to verify the degree of risk for the development of injuries resulting from surgical positioning in patients of a university hospital. Methods: This is cross-sectional, exploratory research with a quantitative approach conducted with 70 surgical patients in a Municipal University Hospital with data collection through a socioeconomic and health questionnaire and the Risk Assessment Scale for Development of Surgical Positioning Injuries (SISP). Statistical analyses included simple descriptive evaluation, correlations of variables using the Chi-square test and Pearson’s coefficient with a significance level of 5%. Results: The results found pointed to a population mainly composed of women (60%), married, with an average age of 49 years, with hypertension and high-risk scores to develop injuries due to surgical positioning. There was also a positive and significant correlation between having hypertension and having a higher risk of developing lesions, with R2 = 96.4% and p Conclusion: The results reinforce the need to implement protocols and the acquisition of materials aimed at reducing the risk of injuries related to surgical positioning in order to improve the quality of care offered and thus minimize the harm to users.

关键词： Nursing Pressure Injury Operating Room

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Prevalence, Risk Factors and Intra-Hospital Outcomes Relating to Peri-Intraventricular Hemorrhage in Premature Newborns of Gestational Age Less than 34 Weeks

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Open Journal of Obstetrics and Gynecology 2021年第7期11卷 898-910页

作者： ana Frante de Holanda Pinto Vasconcelos Kaliny da Silva Galvão Rodrigo Daudt Tenório ana clara Monteiro Laranjeira Délia Maria de M. L. Herrmann Diêgo Lucas Ramos e Silva Juliana Barbosa Nunes Cavalcante Jamille Campos Sousa Euclides Maurício Trindade Filho Biological Science Nucleus Cesmac University Center Maceió Alagoas Brasil Biological Science Nucleus State University of Health Science of Alagoas-UNCISAL Maceió Alagoas Brasil Department of Biological Science Federal University of Alagoas Maceió Alagoas Brasil

Peri-intraventricular hemorrhage is one of the main causes of neurological impairment in premature newborns. To control their risk factors is necessary in view of the increasing survival of extreme preterm infants. Objective: To evaluate the prevalence of peri-intraventricular hemorrhage in premature newborns, identify the risk factors and observe the frequencies of intra-hospital outcomes of interests. Methods: This study was done in Brazil. This was an observational, analytical longitudinal and prospective study. The subjects included were newborns of gestational age less than 34 weeks who were admitted to two public hospitals between May and November 2015. To assess possible associated factors, obstetric, perinatal andana;"> neonatal data were analyzed (chorioamnionitis, antenatal corticosteroids, gestational age, newborn weight, Apgar score at 1 and 5 minutes, resuscitation in the delivery room, surfactant in the delivery room, newborn transferre

关键词： Premature Newborn Peri-Intraventricular Hemorrhage Risk Factors Trans-fontanelle Ultrasonography

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Potential Use of Tropical Grass for Deferment in Semi-Arid Region

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American Journal of Plant Sciences 2014年第7期5卷 907-914页

作者： ana clara R. Cavalcante Jucivania F. Araújo Maria do Socorro Carneiro Henrique A. Souza Rafael G. Tonucci Marcos Cláudio P. Rogerio Elayne Cristina G. Vasconcelos Animal Science Department Federal University of Ceará Fortaleza Brazil Division of Forage and Soil Science Embrapa Goats and Sheep Sobral Brazil

Management evaluation of Panicum maximum cv. massai (Massai guineagrass) under deferment contributes as a strategic reserve of forage in the Brazilian semi-arid region. The objective of this study was to evaluate biomass production and nutritive value of massai guineagrass in an area of thinned caatinga vegetation in two deferment periods (60 and 90 days after plot-leveling cut) and four use periods (30, 60, 90 and 120 days after the end of the rain season), in a random blocks design arranged in a split-plot (2 × 4), with three replications. Extending the deferment period of massai guineagrass promoted elevation of the biomass components, but compromised the pasture quality due to increasing stem biomass. The massai guineagrass deferred 30 days after raining season started and should use 90 days after raining season ended to ensure a forage supply of appropriate nutritional value. The increase in relative air humidity and the occurrence of rainfall after water restriction stimulate regrowth, resulting in improved nutritional value of the grass.

关键词： Enriched Caatinga Crude Protein Digestibility Pasture Quality Guineagrass Panicum maximum cv. Massai

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Standardization of Sampling for Isolation of Exosome-Like Small-Extracellular Vesicles from Peripheral Blood from Reproductive-Aged Women

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Open Journal of Obstetrics and Gynecology 2018年第11期8卷 1063-1070页

作者： Jéssica Maria Diehl Júlia Abbade Tronco Natália Prearo Moco Graziela Gorete Romagnoli ana clara Faquineli Cavalcante Mendes de Avila Juliano Coelho da Silveira Márcia Guimaraes da Silva Bruna Ribeiro de Andrade Ramos Department of Pathology Botucatu Medical School Sao Paulo State University (UNESP) Botucatu Brasil Três Lagoas Integrated College—FITL/AEMS Três Lagoas Brasil Department of Microbiology and Immunology Biosciences Institute Sao Paulo State University (UNESP) Botucatu Brasil Department of Veterinary Medicine Faculty of Zoology and Food Engineering Sao Paulo University Pirassununga Brasil

Exosome-like small-extracellular vesicles (sEVs) are extracellular vesicles that act in intercellular communication and are involved in several biologic and pathologic processes. While sEVs increase the stability of their cargo molecules, there is still a need for standardization of sampling and isolation of these microvesicles. We aimed to determine the best sampling method for isolation of sEVs from peripheral blood from reproductive-aged women. Material and Methods: We included samples of plasma from our biobank collected in 2014 by venipuncture in heparin tubes and stored at -80°C. We also included blood samples collected in heparin tubes and Ethylenediamine tetraacetic acid (EDTA) tubes and stored at -80°C for one to two weeks prior processing. All blood samples were collected from the same nine reproductive-aged female volunteers. sEVs were isolated from plasma by ultracentrifugation and filtration and indirectly quantified using Pierce BCA Protein Assay kit. Transmission electron microscopy (TEM) and Nano Tracking analysis (NTA) were performed to confirm the isolation of sEVs. Results and Discussion: TEM and NTA confirmed the isolation of sEVs. Protein concentration of short-time stored heparin samples was not statistically different from long-time stored heparin samples (1847.2 ± 651.4 vs. 2363.2 ± 1025.1, p = 0.14). There was no difference between heparin and EDTA plasma samples recently collected (2363.2 ± 1025.1 vs. 2044.8 ± 653.2, p = 0.44). In conclusion, blood samples may be collected using heparin or EDTA for isolation of sEVs. Long-time stored plasma samples maintain sEVs integrity and may be used, especially in comparative studies.

关键词： Exosome-Like Small-Extracellular Vesicles Plasma Reproductive-Aged Women

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On the Impact of Brazil's Largest Recent Oil Spill on Regional Oceans

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Sustainable Marine Structures 2021年第2期3卷 1-14页

作者： Liana de Figueiredo Mendes Patricia Pinheiro Beck Eichler Tatiana Leite ana Beatriz Alves Bennemann clara de Souza Melo Andressa Lima Ferreira Khalil Bow Ltaif Garcia Luzia Liniane do Nascimento Silva Christofer Paul Barker Helenice Vital Moab Praxedes Gomes Priscila F.M.Lopes Department of Ecology Federal University of Rio Grande do Norte(UFRN)University CampusLagoa Nova59072-970 NatalRNBrazil Graduate Program in Geodynamics and Geophysics(PPGG) Laboratory of Marine Geology and Geophysics and Environmental MonitoringFederal University of Rio Grande do Norte 0JFRN)University CamposLagoa Nova59072-970 NatalRNBrazil ***(California USA) Department of Ecology and Zoology Federal University of Santa CatarinaTrindade88040-900FlorianopolisSCBrazil

In 2019,an oil spill in Brazil,of unknown origin,severely impacted coastal environs with the worst environmental disaster ever recorded in any tropical coastal region globally severely damaging South Pirangi Reef area in the state of Rio Grande do Norte(RN).Here we discuss acute and chronic impacts including chemical contamination and economic consequences all over the world and show some evidence of the oil spill in this biodiverse ***,the lapse between the moment of the disastei;and the action to manage it,was hampered by a political agenda coinciding with local and global tragedies that redirected public *** almost 2 years have passed still without the offending party identification or culpability;and poor communities may continue to absorb its deleterious impacts for decades without consideration or *** disaster occurred during the Brazilian government's current issues involving extensive environmental mismanagement,resulting in a slow response from an inept *** is with urgent necessity to spotlight this tragedy in this unique and sensitive reef habitat experiencing the ongoing damaging effects that include socio-economic losses not yet addressed.

关键词： Environmental impacts Socioeconomic losses Government Brazilian coast Oil spill Disaster

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车库之家

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现代装饰 2017年第2期 52-57页

作者： Filipe Magalhes ana Luisa Soares Ahmed Belkhodja Mariana Silva Camelia Petre clara Pailler Fernando Guerra(Fg+Sg) 范嘉苑葡萄牙Fala Atelier

将车库改造成住家是怎样的一种体验？葡萄牙的一对夫妇近日将这一想法变成了现实。这两位业主是一对不循规蹈矩的夫妇，他们委托FalaAtelier为其将一间200平米的无窗车库改造成一间舒适的住宅，而且项目预算也非常有限。

关键词：车库项目预算葡萄牙改造业主住宅舒适窗

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Evaluation and Comparison of Medicine Students’ Knowledge about HPV

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Health 2023年第8期15卷 908-916页

作者： clara Vitória Braz Lima de Oliveira Carla Patrícia Alves Barbosa Alexandre Salomão de Barros Oliveira ana Paula Portela Andrade Maria Eduarda Dantas Donald Arthur Carmo da Silva Iva Sampaio Bisneta Francisco Expedito Aguiar Sampaio Alexandre Salomão de Braz Oliveira Elizabeth Bacha Tiradentes University Center (UNIT) Maceió Brazil Chesf Foundation for Assistance and Social Security (FACHESF) Aracaju Brazil Tiradentes University Center (UNIT) Aracaju Brazil Department of Medicine University of Pernambuco (UPE) Recife Brazil

The Human Papillomavirus (HPV) is responsible for almost 99% of cervical cancers. Cervical cancer is a public health problem, being the fourth most common type of tumor among women worldwide and the third most common cancer among women in Brazil. It is known that cervical cancer is one of the most easily preventable forms of cancer, as there is a highly effective vaccine against HPV, however, morbidity and mortality rates related to human papillomavirus are still frightening, especially in less developed countries. Low vaccination adherence rates, especially the second dose, are probably a reflection of the lack of knowledge about this virus, its clinical repercussions, and the vaccine. A clinical trial was carried out in a higher education institution in Alagoas (Brazil), with students of the medical course to whom a validated questionnaire was applied on HPV in the virtual environment (google forms). Data collection was carried out throughout the month of May of the year 2023. It was shown that the knowledge of medical students about the human papillomavirus was less than what would be desired for future doctors. The alert for the acute need to assess health illiteracy is clear, especially regarding cancer that can be prevented by a highly effective vaccine.

关键词： Health Education HPV Health Literacy Cervical Cancer

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超加工食品与全因死亡的关联:SUN前瞻性队列研究

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英国医学杂志中文版 2020年第1期23卷 3-3页

作者： Gómez-Donoso clara anaïs Rico-Campà Miguel A Martínez-González Ismael Alvarez-Alvarez Raquel de Deus Mendonça Carmen de la Fuente-Arrillaga clara Gómez-Donoso Maira Bes-Rastrollo 霍永丰(译) 不详中华医学杂志编辑部

目的评估食用超加工食品与全因死亡的关联。方法前瞻性队列研究。背景西班牙Seguimiento Universidad de Navarra(SUN)大学毕业生队列,1999-2018年。参与者1999年12月-2014年2月对19899位(女性12113位,男性7786位)年龄为20~91岁的受试... 详细信息

目的评估食用超加工食品与全因死亡的关联。方法前瞻性队列研究。背景西班牙Seguimiento Universidad de Navarra(SUN)大学毕业生队列,1999-2018年。参与者1999年12月-2014年2月对19899位(女性12113位,男性7786位)年龄为20~91岁的受试者的膳食和饮品消耗情况每2年进行1次随访,根据NOVA分级标准对食品的加工程度进行分类,利用已经确证的136项食品频率问卷进行评价。主要结局测量利用多变量Cox比例风险模型评估能量校正的超加工食品食用量(分为4个水平:低、中低、中高、高)与全因死亡的关系。结果在全部200432人年的随访期间发生了335例死亡。与食用低水平超加工食品的受试者相比,食用高水平超加工食品的受试者其全因死亡的风险较高(多变量校正危险比为1.62,95%可信区间为1.13~2.33),并且具有显著剂量依赖性(趋势P=0.005)。每多吃一份超加工食品,其全因死亡的风险相比增加18%(校正危险比为1.18,95%可信区间为1.05~1.33)。结论食用较多超加工食品(每日大于4份)与全因死亡风险提高62%独立相关。而每多吃一份超加工食品,全因死亡的风险增加18%。研究注册*** NCT02669602。

关键词： Cox比例风险模型食用量消耗情况多变量校正加工程度可信区间分级标准加工食品

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Treatment of systemic lupus erythematosus with intravenous immunoglobulin （ivIg） and its impact on cellular subsets and immunoregulation

Treatment of systemic lupus erythematosus with intravenous i...

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The 8th International Congress on SLE

作者： Luiz Fernando Goulart clara Pereira ana Monica Gabriel Barbara Leal Maria Francisca Fontes Carlos Vasconcelos Carlos M.Ferreira Jorge Martins Joo Matos-Costa Berta Martins António Marinho Margarida Lima Jocelyne Demengeot Constantin Fesel Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPortugal Hospital Santa MariaLisboaPortugal Instituto Gulbenkian de Ciência OeirasPortugal Instituto de Ciências Biomédicas Abel SalazarPortoPortugal Hospital Geral Santo AntónioPortoPort

＜正＞Purpose:Intavenous immunoglobulin（ivIg）,which has well-demonstrated beneficial effects in various autoimmune diseases,is used as a therapeutic option for Systemic Lupus Erythematosus（SLE）patients,particularly for those with poor responses to standard *** studied immune homeostasis and regulation in patients undergoing this

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DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation andmetabolic remodeling

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Cancer Communications 2023年第7期43卷 838-843页

作者： Sara Mellid Fernando García Luis Javier Leandro-García Alberto Díaz-Talavera Ángel Mario Martínez-Montes Eduardo Gil Bruna Calsina María Monteagudo Rocío Letón Juan María Roldán-Romero María Santos Javier Lanillos Carlos Valdivia Natalia Martínez-Puente Javier de Nicolás-Hernández Scherezade Jiménez Manuel Pérez-Martínez Emiliano Honrado Javier Coloma ana Cerezo clara María Santiveri Manel Esteller Ramón Campos-Olivas Eduardo Caleiras Cristina Montero-Conde Cristina Rodríguez-Antona Javier Muñoz Mercedes Robledo Alberto Cascón Hereditary Endocrine Cancer Group Spanish National Cancer Research Centre(CNIO)MadridSpain Proteomics Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER) MadridSpain Monoclonal Antibodies Core Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Confocal Microscopy Core Unit Spanish National Cancer Research Centre(CNIO)MadridSpain anatomical Pathology Service Hospital of LeónLeónCastilla y LeónSpain Structural Biology Programme Spanish National Cancer Research Centre(CNIO)MadridSpain CNIO-Lilly Cell Signalling and Immunometabolism Section Spanish National Cancer Research Centre(CNIO)MadridSpain Spectroscopy and Nuclear Magnetic Resonance Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Josep Carreras Leukaemia Research Institute(IJC) BadalonaBarcelonaSpain Centro de Investigacion Biomedica en Red Cancer(CIBERONC) MadridSpain Institucio Catalana de Recerca i Estudis Avançats(ICREA) BarcelonaSpain Physiological Sciences Department School of Medicine and Health SciencesUniversity of Barcelona(UB)L’HospitaletBarcelonaSpain Histopathology Core Unit Spanish National Cancer Research Centre(CNIO)MadridSpain Cell Signaling and Clinical Proteomics Group Biocruces Bizkaia Health Research InstituteBarakaldoSpain Ikerbasque Basque Foundation for ScienceBilbaoSpain

Dear Editor,Of all human tumors,pheochromocytomas and paragangliomas(PPGLs)have the highest heritability *** 15%of PPGLs harbor mutations in genes encoding tricarboxylic acid(TCA)cycle-related enzymes that cause oncometabolite accumulation and drive tumorigenesis via metabolic adaptation to hypoxia and global hypermethylation[1].The dihydrolipoamide S-succinyltransferase(DLST)gene was recently described as a new PPGL susceptibility gene[2].

关键词： glioma remodeling cytoma

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