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Natural Products and Bioprospecting 2011年第3期1卷 129-133页

作者： Zhi-qiang pan Ji-Xuan LIANG Jing-Bo CHEN Xiao-Dong YANG Hong-Bin ZHANG Key Laboratory of Medicinal Chemistry for Natural Resource(Yunnan University) Ministry of EducationSchool of Chemical Science and TechnologyYunnan UniversityKunming 650091YunnanChina

A concise synthetic route leading to highly functional erythrina alkaloid skeletons has been *** key process is an oxidative carbon-carbon coupling followed by a conjugated *** on this new strategy,a formal synthesis ... 详细信息

关键词： erythrina alkaloid oxidative dearomation demethoxyerythratidinone formal synthesis

“融媒体”时代突发危机事件微博负面舆情规律预测建模及引导策略分析

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情报科学 2023年第10期41卷 66-71页

作者：潘强哈尔滨工程大学马克思主义学院黑龙江哈尔滨150001

【目的/意义】随着社交媒体的普及和影响力的扩大,突发危机事件往往会在微博等平台引发大量讨论和传播。在极短时间内突发危机事件可能会对事件主体的形象和声誉造成不可逆转的影响,研究突发危机事件微博负面舆情引导策略能够帮助舆情... 详细信息

【目的/意义】随着社交媒体的普及和影响力的扩大,突发危机事件往往会在微博等平台引发大量讨论和传播。在极短时间内突发危机事件可能会对事件主体的形象和声誉造成不可逆转的影响,研究突发危机事件微博负面舆情引导策略能够帮助舆情管理部门有效引导网民负面舆情,提高突发危机事件的应变能力和管理水平。【方法/过程】根据突发危机事件舆情特点建立灰色微分方程,采集突发危机事件历史数据;通过白化微分方程构建舆情规律预测模型,确定突发危机事件爆发临界点;利用残差检验法验证舆情规律预测模型预测结果。【结果/结论】实证分析结果表明,信息公开时间越早,负面舆情越容易得到控制;信息准确度越高,负面舆情传播规模越小;信息完整度越高,负面舆情影响范围越小。【创新/局限】文章提出及时公开信息提升政府公信力、强化信息准确度引导公众理性评判、确保信息完整度提高负面情绪引导效能的策略,以期帮助舆情管理部门更好地控制和化解负面舆情。在后续策略落实中舆情管理部门需要与其他相关部门密切合作,根据舆情规律预测结果及时调整和优化策略。

关键词： “融媒体”时代突发危机事件灰色微分方程舆情规律预测模型负面舆情

Moisture vapor transmission rates of various transparent dressings at different temperatures and humidities

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Chinese Medical Journal 2009年第8期122卷 927-930页

作者： LIN Yu-shuang CHEN Jiong LI qiang pan Ke-ping Department of Bums Third Affiliated Hospital of Wenzhou Medical College Wenzhou Zhejiang 325200 China

Background Transparent dressings are commonly used to cover central venous catheter sites. However, it has been suggested that they might not allow adequate moisture vapor transmission, resulting in local moistness that promotes bacterial growth. We compared the moisture vapor transmission rates （MVTRs） of different, currently used transparent and traditional gauze dressings. We aimed to determine the MVTRs at different temperatures and humidities. Methods The dressings were used to seal 50-ml plastic centrifuge tubes containing 20 ml deionized water： Tubes in group 1 were covered with 12 layers of ordinary gauze, group 2 with IV3000, group 3 with OPSITE FLEXlGRID, group 4 with 3M HP Tegaderm, and group 5 with 3M Tegaderm. The tubes were placed upright in an artificial climate cabinet, so that the dressings were not touching the water, in order to simulate the conditions of medical dressings in contact with the skin. The average MVTRs were determined under different conditions. MVTRs were also determined with tubes from groups 2-5 laid on their sides, allowing the dressings to touch the water, so simulating contact of the dressings with sweating skin, or wounded skin with exudates. We also calculated the dressings＇ self-reactive abilities by comparing their MVTRs in contact with the water surface with those when not in contact with the water surface. Results Group 1 demonstrated the highest MVTR, followed by groups 2, 4, 3 and 5 under conditions simulating contact of the dressings with normal skin at the following temperatures and humidities： 20℃/30%, 20℃/60%, 20℃/90%, 37℃/30%, 37℃/60% and 37℃/90%. When the relative humidity （RH） increased, the MVTRs decreased. The MVTRs differed significantly among different dressings and RHs： At high temperature （37℃） and high humidity （90%）, the MVTR of the transparent dressings in group 2 was higher than that of group 1 （P 〈0.01）. The reactive MVTR was highest in group 2 （10.2-16.3 times 〉MVTR） while that of group 4 was second h

关键词： transparent dressings moisture vapor transmission rates catheter infection

Laws,Defects and Countermeasures on the Circulation of Rural Housing Land——From the Perspective of Farmer Rights Protection

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Asian Agricultural Research 2010年第6期2卷 46-49,55页

作者： MAO Ping SONG Jiao pan qiang College of Politics and Law Sichuan Agricultural UniversityYa’an 625014China

The thesis combs the existing legal provisions about rural housing land from the perspectives of use restriction,means restriction,subject restriction and mortgage prohibition,and finds out their defects,namely,weakening real right,confused knowledge about the integration of house property and land property,the loophole in Land Administration Law,the bans on the rural residents' purchase of housing land and so *** the thesis expounds the harms of restricting the circulation of housing land,for example,it will result in underground transaction of housing lands;lead to untenanted lands and waste of resources;bring about financing difficulty for peasants;do harm to the interest of land owners(rural collective economic organizations) and so *** thesis further proposes to establish the legal lease model to solve the problems in the circulation of housing lands,specifically explains the definition of the legal lease model of housing lands,illustrates its detailed information from the aspects of object,subject and content and elaborates a series of problems involving,how to distribute the rent of housing lands,as well as how to perfect relevant procedures and formalities in the credit circulation of housing lands so as to realize the legitimate and effective circulation of rural housing lands and protect the peasants' interests.

关键词： Circulation of housing lands Legal lease Protection of the peasant's interests China

基于不同专业发展的色彩设计基础课程教学新探索

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装饰 2016年第3期 94-95页

作者：潘强首都师范大学美术学院

笔者对所在院校的色彩课程进行了新的教学探索,在整合装饰色彩、色彩构成课程基础之上,形成色彩训练广度、综合度以及专业拓展度更强的色彩设计基础课程。该课程致力于实现设计人才的色彩新型专业化认识,以基础教学与专业方向性训练相结... 详细信息

笔者对所在院校的色彩课程进行了新的教学探索,在整合装饰色彩、色彩构成课程基础之上,形成色彩训练广度、综合度以及专业拓展度更强的色彩设计基础课程。该课程致力于实现设计人才的色彩新型专业化认识,以基础教学与专业方向性训练相结合,在基础色彩与专业色彩应用中最大程度实现创意思维与应用方法兼容并蓄的创造性人才培养目标。

关键词：色彩设计基础专业导向色彩构成装饰色彩创意思维

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安徽省大型灌区多水源联合运用技术探析

水利水电技术 2013年第9期44卷 127-130页

作者：潘强安徽省水利部淮河水利委员会水利科学研究院水利水资源安徽省重点实验室安徽蚌埠233000

通过总结安徽省大型灌区水源利用现状,提出了对灌区水源联合运用模式与措施,着重对缺水严重的淮北平原灌区地表水与地下水的联合运用进行了探析,为灌区节水改造与续建配套规划提供参考。

关键词：大型灌区水源联合运用安徽省

上海产业知识基础与制度协调研究——基于全球科创中心的建设

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科学学研究 2016年第6期34卷 860-866页

作者：牛盼强上海大学上海电影学院上海200444

上海全球科创中心的建设需要其产业知识基础与制度环境相协调。通过对上海产业知识基础与制度环境的协调进行研究得出结论:经济制度中持续的改革、市场经济的建立和政府的宏观调控为解析型知识基础的发展提供了灵活的制度环境,对上海全... 详细信息

上海全球科创中心的建设需要其产业知识基础与制度环境相协调。通过对上海产业知识基础与制度环境的协调进行研究得出结论:经济制度中持续的改革、市场经济的建立和政府的宏观调控为解析型知识基础的发展提供了灵活的制度环境,对上海全球科创中心的建设非常有利。社会文化制度中的海派文化与白领文化对上海产业知识基础的发展以及科创中心的建设利弊共存。上海的组织规模、所有制结构与产业知识基础类型是相匹配的,但外资经济本土化创新网络仍需加强。

关键词：产业知识基础经济制度社会文化制度组织制度全球科创中心

Serum M2-pyruvate kinase: A promising non-invasive biomarker for colorectal cancer mass screening

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World Journal of Gastrointestinal Oncology 2012年第6期4卷 145-151页

作者： Wen Meng Hong-Hong Zhu Ze-Feng Xu Shan-Rong Cai Qi Dong qiang-Rong pan Shu Zheng Su-Zhan Zhang Zhejiang Univ Canc Inst Key Lab Canc Prevent & Intervent China Natl Minist EducKey Lab Mol Biol Med Sci Hangzhou 310009 Zhejiang Peoples R China Zhejiang Univ Affiliated Hosp 2 Sch Med Hangzhou 310009 Zhejiang Peoples R China Hangzhou First Peoples Hosp Dept Cardiothorac Surg Hangzhou 310006 Zhejiang Peoples R China Capella Univ Sch Publ Serv Leadership Dept Hlth Adm Publ Hlth & Gerontol Minneapolis MN 55403 USA St Louis Univ Sch Publ Hlth Dept Community Hlth St Louis MO 63104 USA Western Kentucky Univ Coll Hlth & Human Serv Dept Publ Hlth Bowling Green KY 42101 USA

AIM: To explore the value of serum M2-pyruvate kinase (M2-PK) in colorectal cancer (CRC) mass screening. METHODS: We conducted a molecular epidemiology study in Hangzhou, China, from year 2006 to year 2008. Serum samples were collected from 93 CRC, 41 advanced adenomas, 137 adenomas, 47 non-adenomatous polyps, and 158 normal participants in a community setting. Serum M2-PK and carcinoembryonic antigen (CEA) were measured using Enzyme-linked immunosorbent assay. SPSS 16.0 software was used to perform data analysis. Area under the receiver operating characteristic curve (AUC), sensitivity, and specificities were estimated for serum M2-PK in diagnosis of colorectal lesions and compared with CEA. RESULTS: Average serum M2-PK value among 158 normal people was 2.96 U/mL and not affected by gender (P = 0.47) or age (P = 0.59). Average serum M2-PK (U/mL) was 14.75 among stage III and 13.10 among stage?I?and II CRC patients, about 4 times higher than that among normal people. Average serum M2-PK was 8.58, 6.70, 5.13 and 2.51 U/mL among advanced adenoma, adenomas, non-adenomatous polyps, and inflammatory bowel disease patients, respectively. AUC for serum M2-PK was greater than that for CEA among all colorectal lesions. AUC for serum M2-PK was 0.89 (0.84, 0.94) (95% confidence interval), higher than that for CEA [0.70 (0.62-0.79)] in CRC stage?I?and II, 0.89 (0.84-0.94) vs 0.73 (0.63-0.83) in CRC stage III, 0.81 (0.74-0.86) vs 0.63 (0.53 - 0.73) in advanced adenomas, 0.69 (0.64-0.76) vs 0.54 (0.47-0.60) in adenomas, and 0.69 (0.62-0.78) vs 0.58 (0.48-0.68) in non-adenomatous polyps. The diagnostic sensitivity for all colorectal lesions increased with decrease in the cut-off value of serum M2-PK. The diagnostic sensitivity (%) of serum M2-PK was 100.00 for CRC, 95.12 advanced adenoma, 82.48 adenoma, and 82.98 non-adenomatous polyp. There were no CRC cases missed and 40.51% of unnecessary colonoscopies were avoided when the cut-off value was 2.00 U/mL. CONCLUSION: Serum M2-PK c

关键词： Serum M2-pyruvate kinase Colorectal cancer screening Serum biomarker Carcinoembryonic antigen

Design of a Smart Sole with Advanced Fall Detection Algorithm

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Journal of Sensor Technology 2019年第4期9卷 71-90页

作者： Mostapha Zitouni qiang pan Damien Brulin Eric Campo LAAS-CNRS Université Toulouse Jean Jaurès Toulouse France

Fall has become the second leading cause of unintentional injury, death, after road traffic injuries, for the elderly in Europe. This proportion will increase in the next decades and become more than ever a real public health issue. France was selected by the World Health Organization to be the first country to implement a program that reduces the coverage of the dependence. Commercial automatic fall detection devices can help seniors get back on their feet faster by reducing the time of emergency procedure. Many seniors do not take advantage of this potentially life-saving technology mainly because of intrusiveness constraints. After having reminded the context and the challenges of fall detection systems, this paper presents an original device which is unobtrusive, comfortable and very effective. The hardware architecture embedded into the sole and a new fall detection algorithm based on acceleration and time thresholds are presented. The algorithm introduces a new concept of differential acceleration to eliminate some drawbacks of current systems. Tests were carried out under real life conditions by 6 young participants for different ADLs. The data were analyzed blindly. We compared the detected falls and found a 100% sensibility and more than 93% sensitivity for all participants and scenarios.

关键词： Fall Detection Elderly Accelerometer Smart Insole Classification

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原发性免疫缺陷病研究进展

中华儿科杂志 2007年第11期45卷 804-808页

作者： qiang pan-Hammarstrom Lennart Hammarstrom 刘崇海（翻译）杨锡强（审校） m 瑞典卡罗琳斯学院大学医院临床免疫学／医学实验室se14186 不详

原发性免疫缺陷病（primaryimmunodeficiencydiseases，PID）是以免疫系统细胞或其构成成分的数量或质量缺陷，以致易发生各种感染为突出特征的少见疾病。在不同基因调控下，干细胞经历系列的、非连续性发育阶段，最终分化为各种成熟的... 详细信息

原发性免疫缺陷病（primaryimmunodeficiencydiseases，PID）是以免疫系统细胞或其构成成分的数量或质量缺陷，以致易发生各种感染为突出特征的少见疾病。在不同基因调控下，干细胞经历系列的、非连续性发育阶段，最终分化为各种成熟的免疫活性细胞。这些调控基因的突变／缺失会导致相应细胞系分化受阻（图1），导致大多数免疫缺陷（有些免疫缺陷并非这一途径障碍，如补体缺陷）。迄今为止，已发现150多种不同类型的免疫缺陷，且大多数缺陷的遗传基础已清楚。

关键词：原发性免疫缺陷病免疫系统细胞免疫活性细胞质量缺陷少见疾病基因调控发育阶段调控基因