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Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury

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Neural Regeneration Research 2025年第10期20卷 2807-2822页

作者： Xizi Song Ruixin li Xiaolei Chu qi li Ruihua li qingwen li Kai-Yu Tong Xiaosong Gu Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Haihe Laboratory of Brain-Machine Interface and Human-Machine Fusion TianjinChina Department of Rehabilitation Tianjin University Tianjin HospitalTianjinChina Department of Hand Microsurgery Tianjin University Tianjin HospitalTianjinChina School of Exercise and Health Tianjin University of SportTianjinChina Department of Biomedical Engineering the Chinese University of Hong KongHong Kong Special Administrative RegionChina

Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and *** on the pathogenesis of peripheral nerve injury has focused on pathological changes at individual injury sites,neglecting multilevel pathological analysis of the overall nervous system and target *** has led to restrictions on current therapeutic *** this paper,we first summarize the potential mechanisms of peripheral nerve injury from a holistic perspective,covering the central nervous system,peripheral nervous system,and target *** peripheral nerve injury,the cortical plasticity of the brain is altered due to damage to and regeneration of peripheral nerves;changes such as neuronal apoptosis and axonal demyelination occur in the spinal *** nerve will undergo axonal regeneration,activation of Schwann cells,inflammatory response,and vascular system regeneration at the injury *** damage to target organs can occur,including skeletal muscle atrophy and sensory receptor *** then provide a brief review of the research advances in therapeutic approaches to peripheral nerve *** main current treatments are conducted passively and include physical factor rehabilitation,pharmacological treatments,cell-based therapies,and physical ***,most treatments only partially address the problem and cannot complete the systematic recovery of the entire central nervous system-peripheral nervous system-target organ ***,we should further explore multilevel treatment options that produce effective,long-lasting results,perhaps requiring a combination of passive(traditional)and active(novel)treatment methods to stimulate rehabilitation at the central-peripheral-target organ levels to achieve better functional recovery.

关键词： central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach

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Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

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Nano Research 2025年第1期18卷 443-454页

作者： Wei Wang Zi-qing Chen Yong-qi li Yu-Long Wang Mei-Chen liu Yun-Bo Ruan Yang Zhang Shu-Juan liu qiang Zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe Jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVliG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVliG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVliG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric

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THE PERTURBATION PROBLEM OF AN ELliPTIC SYSTEM WITH SOBOLEV CRITICAL GROWTH

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Acta Mathematica Scientia 2020年第5期40卷 1391-1404页

作者： qi li School of Mathematics and Statistics Central China Normal UniversityWuhan 430079China

In this paper,we study the following perturbation problem with Sobolev critical exponen t:{-Δu=(1+εK(x))u^2*-1+α/2*u^a-1v^3+εh(x)u^pP,x∈R^N,-Δu=(1+εQ(x))v^2*-1+β/2*u^B-1+εl(x)u^q,x∈R^N,u>0,v>0,x∈R^N where 0... 详细信息

关键词： perturbation argument finite dimensional reduction method critical exponent

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A group priority earliest deadline first scheduling algorithm

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Frontiers of Computer Science 2012年第5期6卷 560-567页

作者： qi li Wei BA School of Control Science and Engineering Dalian University of TechnologyDalian 116024China Science and Technology on Underwater Test and Control Laboratory Dalian 116013China

In most priority scheduling algorithms, the num- ber of priority levels is assumed to be unlimited. However, if a task set requires more priority levels than the system can support, several jobs must in practice be assigned the same priority level. To solve this problem, a novel group priority earliest deadline first （GPEDF） scheduling algorithm is pre- sented. In this algorithm, a schedulability test is given to form a job group, in which the jobs can arbitrarily change their or- der without reducing the schedulability. We consider jobs in the group having the same priority level and use shortest job first （SJF） to schedule the jobs in the group to improve the performance of the system. Compared with earliest deadline first （EDF）, best effort （BE）, and group-EDF （gEDF）, simu- lation results show that the new algorithm exhibits the least switching, the shortest average response time, and the fewest required priority levels. It also has a higher success ratio than both EDF and gEDF.

关键词： real-time system group priority success ratio,switching

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ADAPTIVE SET STABIliZATION OF THE ATTITUDE OF A RIGID SPACECRAFT WITHOUT ANGULAR VELOCITY MEASUREMENTS

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Journal of Systems Science & Complexity 2011年第1期24卷 105-119页

作者： Shihong DING Shihua li qi li School of Automation Southeast University Nanjing 210096 China College of Electrical and Information Engineering Jiangsu University Zhenjiang 212013 China School of Automation Southeast University Nanjing 210096 China

The global adaptive set stabilization problem of the attitude of a rigid spacecraft is addressed in this paper. Two different cases are considered. First, by using adaptive backstepping method, the authors design a global adaptive control law for the attitude control system with unknown inertia matrix such that the attitude and the angular velocities can be globally asymptotically stabilized to a set consisting of two equilibria. And then, based on the obtained backstepping adaptive law, the authors consider the case that the angular velocities are not measurable. By introducing an auxiliary state, a semi-global adaptive set stabilization law without angular velocity measurements is also designed. It is rigorously proved that, for the two cases, both of the closed loop systems satisfy the set stability. The effectiveness of the proposed methods is verified by simulation results.

关键词： Adaptive control attitude stabilization backstepping quaternion spacecraft.

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TiO2-based photocatalysts prepared by oxidation of TiN nanoparticles and their photocatalytic activities under visible light illumination

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Journal of Materials Science & Technology 2018年第6期34卷 969-975页

作者： Chao li Weiyi Yang qi li Environment Functional Materials Division Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences Shenyang 110016 China University of Chinese Academy of Sciences Beijing 100049 China

To develop TiO2-based photocatalysts with visible light activity for better solar energy utilization, a simple flash oxidation method was developed by calcining commercial TiN nanoparticle to prepare N-doped TiO2 photocatalyst and TiN/TiO2 composite photocatalysts through the modulation of the calcination time and temperature. It was found that more energy and processing time were needed to prepare N-doped TiO2 photocatalyst than that of TiN/TiO2 composite photocatalyst during this process, while TiN/TiO2 composite photocatalyst bad a better visible light absorption/photocatalytic performance than that of N-doped TiO2 photocatalyst prepared from the oxidation of the same TiN precursor. Thus, the preparation of TiN/TiO2 composite photocatalyst from TiN precursor should be a more preferred approach than the preparation of N-doped TiO2 photocatalyst for visible-light-activated photocatalysis for its costeffectiveness.

关键词： N-doped TiO2 TiN/TiO2 Localized surface plasmon resonance (LSPR) Visible-light-activated photocatalysis

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Biochemical and microbial properties of rhizospheres under maize/ peanut intercropping

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Journal of Integrative Agriculture 2016年第1期15卷 101-110页

作者： li qi-song Key Laboratory of Biopesticide and Chemical Biology Ministry of Education/College of Life Sciences Fujian Agriculture and Forestry University Fuzhou 350002 P.R.China Agroecological Institute Fujian Agriculture and Forestry University Fuzhou 350002 P.R.China Department of Horticulture Pir Mehr Ali Shah Arid Agriculture University Rawalpindi 46300 Pakistan

Maize/peanut intercropping system shows the significant yield advantage. Soil microbes play major roles in soil nutrient cycling and were affected by intercropping plants. This experiment was carried out to evaluate the changing of rhizosphere microbial community composition, and the relationship between microbial community and soil enzymatic activities, soil nutrients in maize/peanut intercropping system under the following three treatments： maize （Zea mays L.） and peanut （Arachis hypogaea L.） were intercropped without any separation （NS）, by half separation （HS） using a nylon net （50 μm） and complete separation （CS） by using a plastic sheet, respectively. The soil microbial communities were assessed by phospholipid fatty acid （PLFA）. We found that soil available nutrients （available nitrogen （Avail N） and available phosphorus （Avail P）） and enzymatic activities （soil urase and phosphomonoesterase） in both crops were improved in NS and HS treatments as compared to CS. Both bacterial and fungal biomasses in both crops were increased in NS followed by HS. Furthermore, Gram-positive bacteria （G＋） in maize soils were significant higher in NS and HS than CS, while the Gram-negative （G-） was significant higher in peanut soil. The ratio of normal saturated to monounsaturated PLFAs was significantly higher in rhizosphere of peanut under CS treatment than in any other treatments, which is an indicator of nutrient stress. Redundancy analysis and cluster analysis of PLFA showed rhizospheric microbial community of NS and HS of both plants tended to be consistent. The urase and Avail N were higher in NS and HS of both plants and positively correlated with bacteria, fungi （F） and total PLFAs, while negatively correlated with G＋/G- and NS/MS. The findings suggest that belowground interactions in maize/peanut intercropping system play important roles in changing the soil microbial composition and the dominant microbial species, which was closely related with the improving of soil

关键词： maize/peanut intercropping phospholipid fatty acid soil nutrient soil enzymes

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Rotating Bardeen black hole surrounded by perfect fluid dark matter as a particle accelerator

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Communications in Theoretical Physics 2023年第10期75卷 111-120页

作者： qi-Quan li Yu Zhang qian li qi Sun Faculty of Science Kunming University of Science and TechnologyKunmingYunnan 650500China

We study the event horizon of a rotating Bardeen black hole surrounded by perfect fluid dark matter and the black hole as a particle *** black hole is represented by four parameters:mass M,rotation parameter a,dark matter parameterαand magnetic charge *** is interesting that when we determine the values of magnetic charge g and dark matter parametersαwe can get a critical rotation parameter aEand then we get a contour plane withΔ=0 taking three parameters as *** also derive the effective potential of the particle and the center-of-mass(CM)energy of the two particles outside the black hole by using the motion equations of the particle in the equatorial plane of the black *** find that the CM energy depends not only on the rotation parameter a,but also on the parameters g andα.We discuss the CM energy for two particles colliding at the black hole horizon in the extreme and non-extreme cases,*** is found that the CM energy can become arbitrarily high when the angular momentum of one of the two particles is the critical angular momentum under the background of extreme black holes and there is no such result for non-extreme black holes,because the particles do not reach the black hole horizon when the angular momentum of the particles is critical angular ***,we prove that the rotating Bardeen black hole surrounded by perfect fluid dark matter can be used as a particle accelerator.

关键词： black hole particle accelerator critical angular momentum center-of-mass(CM)energy

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Ice-Class Propeller Strength and Integrity Evaluation Using Unified Polar ClassURI3 Rules

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Journal of Ocean University of China 2021年第4期20卷 823-836页

作者： li qi liU Pengfei Australian Maritime College University of TasmaniaLauncestonTasmania 7250Australia Marine Offshore and Subsea TechnologySchool of EngineeringNewcastle UniversityNewcastle upon TyneNE17RUUK

A systematic method was developed for ice-class propeller modeling,performance estimation,strength and integrity evaluation and *** estimate the impact of sea ice on the propeller structure,URI3 rules,established by the International Association of Classification Societies in 2007,were applied for ice loading *** R-class propeller(a type of ice-class propeller)was utilized for subsequent *** propeller modeling was simplified based on a conventional method,which expedited the model building *** propeller performance was simulated using the computational fluid dynamics(CFD)*** simulation results were validated by comparison with experimental ***,the hydrodynamic pressure was transferred into a finite element analysis(FEA)module for strength assessment of ice-class *** to URI3 rules,the ice loading was estimated based on different polar classes and working ***,the FEA method was utilized to evaluate the propeller *** validation showed that the simulation results accorded with recent research ***,an improved optimization method was developed to save the propeller constituent *** optimized propeller example had a minimum safety factor of 1.55,satisfying the safety factor requirement of≥1.5,and reduced the design volume to 88.2%of the original.

关键词： polar class propeller URI3 rules propeller blade strength and integrity design and optimization ice-class propeller hydrodynamics-strength coupled

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Impacts of Low Salinity Stress on Physiological Responses of the Gill in the Iwagaki Oyster Crassostrea nippona

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Journal of Ocean University of China 2024年第6期23卷 1608-1614页

作者： GONG Jianwen li qi Key Laboratory of Mariculture Ministry of EducationOcean University of ChinaQingdao 266003China

Crassostrea nippona is a valuable species for aquaculture with considerable potential for commercial oyster ***,it is vulnerable to changes in salinity levels in coastal *** this study,we investigated the impacts of low salinity stress on the physiological responses of *** hemolymph osmolality could not reach equilibrium with the surrounding environmental osmolality that was below salinity 15 within 1 *** expansion,cellular valuocation,decrease of gill cilia,increased apoptotic cells under salinity 10 were observed through microscopic *** activities of immunity-related enzymes,including alkaline phosphatase(AKP),acid phosphatase(ACP),superoxide dismutase(SOD),and catalase(CAT),were significantly increased at salinity 10 compared with the control *** findings highlight the vulnerability of *** to low salinity stress and provide insights into the physiological changes in response to fluctuating salinity *** these physiological responses is crucial for effective aquaculture management and developing strategies to mitigate the negative impacts of low salinity stress on *** populations in coastal areas.

关键词： Crassostrea nippona low salinity stress hemolymph osmolality enzyme fine structure

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