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World Journal of Clinical Cases 2019年第4期7卷 516-524页

作者： Jia-min chen Ying Yan Department of Prosthodontics Guanghua School of StomatologyHospital of Stomatology Sun Yat-sen University Guangdong Provincial Key Laboratory of Stomatology

BACKGROUND Bruxism is a jaw-muscle activity characterized by the clenching or grinding of teeth. It can be divided into nocturnal bruxism and diurnal bruxism(DB). DB secondary to antidepressants is rare and refractory. Reports associated with antidepressant-induced DB are mostly anecdotal without long-term *** effect of drug intervention on antidepressant-induced DB is still *** herein report the first case of successful treatment of venlafaxine-induced DB with an occlusal *** SUMMARY This case report describes detailed 7-year follow-up of a patient with venlafaxineinduced DB treated with an occlusal splint. The patient who complained about involuntary daytime tooth grinding after taking venlafaxine for a period of 4 mo and was diagnosed with venlafaxine-induced DB. Subsequently, an occlusal splint with modified bilateral buccal-pterygoid pads was used to treat his tooth grinding and to protect the dental structures from tooth wearing. The patient reported remission of symptoms after several months of treatment. His grinding activity was gradually and stably controlled after 2 years, with an almost complete recovery from DB after 6 *** The maxillary buccal-pterygoid splint can be used as a noninvasive approach to treat venlafaxine-induced DB.

关键词： Occlusal splint Venlafaxine Diurnal bruxism Tooth grinding Movement disorders Treatment Case report

Study of ss-DNA Adsorption and Nano-mechanical Properties on Mica Substrate with Surface Forces Apparatus

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Chinese Journal of Mechanical Engineering 2018年第5期31卷 91-98页

作者： Gui-Bin Shen Ya-Jing Kan min-Hua chen Yun-Fei chen Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments Southeast University Nanjing 211189 China School of Mechanical Engineering Southeast University Nanjing 211189 China

Many DNA?based devices need to build stable and controllable DNA films on surfaces. However, the most com?monly used method of film characterization, namely, the probe?like microscopes which may destroy the sample and substrate. Surface Forces Apparatus(SFA) technique, specializing in surface interaction studies, is introduced to investigate the e ects of DNA concentration on the formation of single?stranded DNA(ss?DNA) film. The result demonstrates that 50 ng/μL is the lowest concentration that ss?DNA construct a dense layer on mica. Besides, it is also indicated that at di erent DNA concentrations, ss?DNA exhibit diverse morphology: lying flat on surface at 50 ng/μL while forming bilayer or cross?link at 100 ng/μL, and these ss?DNA structures are stable enough due to the repeatabil?ity even under the load of 15 mN/m. At the same time, an obvious adhesion force is measured:/m at 100 ng/μL, respectively, which is attributed to the ion?correlation e ect. M-6.5 mN/m at 50 ng/μL and-5.3 mNoreover, the atomic force microscopy(AFM) images reveal the entire surface is covered with wormlike ss?DNA and the measured surface roughness(1.8±0.2 nm) also matches well with the film thickness by SFA. The desorption behaviors of ss?DNA layer from mica surface occur by adding sodium salt into gap bu er, which is mainly ascribed to the decreased ion?ion cor?relation force. This paper employing SFA and AFM techniques to characterize the DNA film with flexibility and stable mechanical ability achieved by ion bridging method, is helpful to fabricate the DNA?based devices in nanoscale.

关键词： Single?stranded DNA Adsorption Nano?mechanical properties Ion?correlation effect Surface forces apparatus

Modeling of sensor function for piezoelectric bender elements

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第1期9卷 1-7页

作者： Yan-guo ZHOU Yun-min chen Hao-jiang DING Wei-qiu chen Key Laboratory of Soft Soils and Geoenvironmental Engineering Ministry of Education Zhejiang University Hangzhou 310027 China

An analytical sandwich beam model for piezoelectric bender elements is derived based on the first-order shear deformation theory (FSDT), which assumes a single rotation angle for the whole cross-section and a quadratic distribution for coupled electric potential in piezoelectric layers. Shear coefficient is introduced to correct the effect of transverse shear strain on shear force and the electric displacement integration. Static and free vibration analyses of simply-supported bender elements are carried out for the sensor function. The results illustrate the high accuracy of the present model compared with the exact 2D solutions.

关键词： Bender elements Piezoelectric Sensor Sandwich beam Shear coefficient

Peripheral Ferroelectric Domain Switching and Polarization Fatigue in Nonvolatile Memory Elements of Continuous Pt/SrBi_(2)Ta_(2)O_(9)/Pt Thin-Film Capacitors

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Chinese Physics Letters 2011年第7期28卷 275-277页

作者： chen min-Chuan JIANG An-Quan State Key Laboratory of ASIC&System Department of MicroelectronicsFudan UniversityShanghai 200433

We verify the domain sideway motion around the peripheral regions of the crossed capacitors of top and bottom electrode bars without electrode *** avoid the crosstalk problem between adjacent memory cells,the safe distance between adjacent elements of Pt/SrBi_(2)Ta_(2)O_(9)/Pt thin−film capacitors is estimated to be 0.156µ***,the fatigue of Pt/SrBi_(2)Ta_(2)O_(9)/Pt thin-film capacitors is independent of the individual memory size due to the absence of etching damage.

关键词： electrode volatile film

Study on the Interface Bonding and Bending Fatigue Properties of Aluminum Alloy Foam Sandwich

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稀有金属材料与工程 2009年第A03期38卷 119-122页

作者： Zhang min chen Changjun Chang Qingming Key Laboratory for Ferrous Metallurgy and Resources Utilization of ministry of Education Wuhan University of Science ＆ Technology Wuhan 430081 China

Foam materials have many attractive properties because of their low-weight and cell structure. By sandwiches with an aluminum-foam core, it is possible to obtain higher structural stiffness and rigidity, maintain stability against buckling and additionally make use of the high energy dissipation capability of the bare foams. The most obvious and straightforward one is adhesive bonding of pre-fabricated aluminum foams and metal face sheets. A new manufacture processing is proposed for preparation of aluminum alloy foam sandwich, ie., Al-plate/mixed element powder/ Al-plate are sandwich rolled together by a large reduction in pass, which is then foamed in heating furnace to manufacture end-use product. Aluminum alloy foam sandwich is obtained in this experiment. The experimental results showed that the process of rolling interface belongs to mechanical bonding, whose mechanism is film theory. While interface bonding belong to metallurgy bonding in the process of foaming, Al atom interdiffused in the interface, and no new phase was generated in the foaming process of aluminum face sheet/powders precursor. Bending fatigue test results showed that the bonding force of the foamed sandwich interface is very high, in fatigue test fracture occurred in the whole foam aluminum sandwich panels and Al/foam core interface was not laminated.

关键词：泡沫材料复合材料泡沫塑料物理性能

Influence of injection of Chinese botulinum toxin type A on the histomorphology and myosin heavy chain composition of rat gastrocnemius muscles

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第11期14卷 983-992页

作者： Bin HONG min chen Xing-yue HU Department of Neurology Sir Run Run Shaw HospitalSchool of MedicineZhejiang University Department of Endocrinology the First Affiliated HospitalSchool of MedicineZhejiang University

Background and objective:Botulinum toxin type A(BoNT/A)is a metalloprotease that blocks synaptic transmission via the cleavage of a synaptosomal-associated protein of 25 kDa(SNAP-25).It has gained widespread use as a treatment for cerebral palsy and skeletal muscle *** China,Chinese botulinum toxin type A(CBTX-A),a type of BoNT/A,is in widespread clinical ***,the changes in the morphological and biochemical properties of treated muscles and in remote muscles from the CBTX-A injection site are relatively ***,we investigated the changes in histomorphology and myosin heavy chain(MyHC)isoform composition and distribution in rat gastrocnemius muscles after intramuscular injection of ***:The weakness of the injected muscles was assessed periodically to identify their functional *** slices were stained with hematoxylin-eosin(HE)and adenosine triphosphatase(ATPase).MyHC isoform composition was analyzed by sodium dodecyl sulfatepolyacrylamide gel electrophoresis(SDS-PAGE)to uncover changes in morphological and biochemical ***:Our findings demonstrate that following injection of CBTX-A 5 U into rat gastrocnemius muscles,shifts in MyHC isoform composition emerged on the third day after injection and peaked in the fourth *** composition remained distinctly different from that of the control group after the twelfth *** specifically,there was a decrease in the proportion of the type IIb isoform and an increase in the proportions of type IIx,type IIa,and type I ***:Data revealed that CBTX-A led to a shift in MyHC composition towards slower isoforms and that the MyHC composition remained far from normal six months after a single ***,no noticeable remote muscle weakness was induced.

关键词： Botulinum toxin type A(BoNT/A) Myosin heavy chain Chemodenervation Remote effect

Statistical Inference on Seemingly Unrelated Single-Index Regression Models

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Acta Mathematicae Applicatae Sinica 2016年第4期32卷 945-956页

作者： Bing HE Jin-hong YOU min chen School of Mathematics Jilin University School of Statistics and Management Shanghai University of Finance and Economics Academy of Mathematics and Systems Science Chinese Academy of Sciences

In this article, we consider a class of seemingly unrelated single-index regression models. By taking the contemporaneous correlation among equations into account we construct the weighted estimators （WEs） for unknown parameters of the coefficients and the improved local polynomial estimators for the unknown functions, respectively. We establish the asymptotic normalities of these estimators, and show both of them are more asymptotically efficient than those ignoring the contemporaneous correlation. The performances of the proposed procedures are evaluated through simulation studies.

关键词： seemingly unrelated contemporaneous correlation single-index weighted estimation

Characteristics of Fluid Flow and Temperature Field of Twin-roll Steel Strip Casting with a Novel-type Delivery System

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Journal of Iron and Steel Research International 2015年第10期22卷 885-891页

作者： Jian-hong DONG min chen Nan WANG School of Materials and Metallurgy Northeastern University

A novel-type delivery system consisting of a special feeding device and delivery device was developed and applied to a φ600 mm× 1 000 mm twin-roll casting system for producing the steel strip of 2 mm in thickness, and the characteristics of fluid flow and temperature field in the casting pool were investigated by mathematical simulation. The results showed that the melt from the novel-type delivery system was distributed to the casting pool along the width direction smoothly and uniformly. At the casting speed of 80 m/min, the difference of minimum residence time （groin） and actual average residence time （tave） among different ports of the delivery device was less than 0.18 s and 0.26 s respectively, and the average amplitude of level fluctuation was 0.3 mm to 0.6 mm on the free surface of casting pool. In addition, the difference of temperature on the free surface of the pool was below 20 K and the difference across the width direction of roll in different pool depths was less than 13 K, which indicates that the uniformity of temperature distribution was obtained in the casting pool to maintain the casting process and the defect-free steel strip can also be obtained.

关键词： twin-roll strip casting novel-type delivery system fluid flow temperature field mathematical simulation

Empirical Likelihood-Based Subset Selection for Partially Linear Autoregressive Models

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Acta Mathematicae Applicatae Sinica 2013年第4期29卷 793-808页

作者： Yu HAN Ying-hua JIN min chen College of Mathematics Jilin University College of Science Northeast Dianli University Academy of Mathematics and Systems Science Chinese Academy of Sciences

Based on the empirical likelihood method, the subset selection and hypothesis test for parameters in a partially linear autoregressive model are investigated. We show that the empirical log-likelihood ratio at the true parameters converges to the standard chi-square distribution. We then present the definitions of the empirical likelihood-based Bayes information criteria （EBIC） and Akaike information criteria （EAIC）. The results show that EBIC is consistent at selecting subset variables while EAIC is not. Simulation studies demonstrate that the proposed empirical likelihood confidence regions have better coverage probabilities than the least square method, while EBIC has a higher chance to select the true model than EAIC.

关键词： subset selection empirical likelihood partial linear autoregressive model

Lewis Base Catalyzed Selenofunctionalization of Alkynes with Acid-Controlled Divergent Chemoselectivity

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Chinese Journal of Chemistry 2024年第14期42卷 1623-1629页

作者： Ling-Ling chen Ren-Fei Cao Hua Ke Zhi-min chen School of Chemistry and Chemical Engineering Shanghai Key Laboratory for Molecular Engineering of Chiral DrugsShanghai Jiao Tong UniversityShanghai200240 China Engineering Technology Research Center for Environmental Protection Materials Pingxiang UniversityPingxiangJiangxi337055 China

Lewis base catalyzed and Brønsted acid controlled chemodivergent electrophilic selenofunctionalizations of alkynes were developed for the first *** selenium-containing tetrasubstituted alkenes were readily obtained in moderate to excellent yields with complete E/Z *** the substrates were 1-ethynyl naphthol derivatives,linear selenium-containing tetrasubstituted alkenes were produced via intermolecular oxygen nucleophilic attack in the absence of acid additive;in contrast,cyclic selenium-containing tetrasubstituted alkenes were generated through intramolecular carbon nucleophilic capture with the addition of Brønsted acid.

关键词： Alkynes Electrophilic addition Chemoselectivity Lewis base catalysis Selenofunctionalization