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Tension pneumocephalus following endoscopic resection of a mediastinal thoracic spinal tumor:A case report

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World Journal of Clinical Cases 2022年第2期10卷 725-732页

作者： Chao-Yuan Chang cheng-che Hung Ju-Mien Liu cheng-Di Chiu Department of Neurosurgery China Medical University HospitalTaichung 40447Taiwan Department of Pathology Puli Christian HospitalNantou 54041Taiwan

BACKGROUND Pneumocephalus is a rare complication presenting in the postoperative period of a thoracoscopic *** report a case in which tension pneumocephalus occurred after thoracoscopic resection as well as the subsequent approach of surgical *** SUMMARY A 66-year-old man who received thoracoscopic resection to remove an intrathoracic,posterior mediastinal,dumbbell-shaped,pathology-proven neurogenic *** patient then reported experiencing progressively severe headaches,especially when in an upright position.A brain computed tomography scan at a local hospital disclosed extensive *** surgery for resection of the pseudomeningocele and repair of the cerebrospinal fluid leakage was thus arranged for the *** the operation,we traced the cerebrospinal fluid leakage and found that it might have derived from incomplete endoscopic clipping around the tumor stump near the dural sac at the T3 *** that,we wrapped and sealed all the possible origins of the leakage with autologous fat,tissue glue,gelfoam,and duraseal layer by *** patient recovered well,and the computed tomography images showed resolution of the *** This report and literature review indicated that the risk of developing a tension pneumocephalus cannot be ignored and should be monitored carefully after thoracoscopic tumor resection.

关键词： Tension pneumocephalus Neurogenic tumor Thoracoscope Case report

Combined immune checkpoint inhibitors of CTLA4 and PD-1 for hepatic melanoma of unknown primary origin: A case report

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World Journal of Clinical Cases 2021年第11期9卷 2641-2648页

作者： an-che cheng Yi-Jia Lin Sung-Hua Chiu Yu-Lueng Shih Department of Internal Medicine Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Department of Pathology Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Department of Radiology Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Department of Internal Medicine Division of GastroenterologyTri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan

BACKGROUND Melanoma is uncommonly found in lymph nodes,subcutaneous tissue,or visceral organs without a primary lesion,where it is identified as metastatic melanoma with unknown primary(MUP).Hepatic MUP is extremely rare and has a poor *** is limited information on its pathogenesis,clinical and imaging features,and pathological *** are no guidelines for the use of immune checkpoint inhibitors(ICIs)in hepatic MUP,and the treatment outcome has rarely been *** SUMMARY A 42-year-old woman presented to our hospital with hepatic tumors found incidentally during a routine ***-enhanced abdominal computerized tomography showed multiple mass lesions in the *** results revealed melanoma,which was confirmed by immunohistochemical staining for HMB-45(+),Melan-A(+),S-100(+),and SOX10(+).There was no evidence of primary cutaneous,ocular,gastrointestinal,or anal lesion on a comprehensive *** patient was diagnosed with hepatic *** received combined antibodies against cytotoxic T-lymphocyte-associated antigen 4(CTLA-4,ipilimumab)and programmed death protein-1(PD-1,nivolumab).She died of hepatic failure 9 mo after hepatic MUP was *** the first case of hepatic MUP treated with combined ipilimumab and nivolumab,who showed better outcome than previous *** ICIs of PD-1 and CTLA-4 may be considered as the first-line therapyfor patients with hepatic MUP.

关键词： Metastatic melanoma with unknown primary Liver metastasis Immune checkpoint inhibitor Programmed death protein-1 Cytotoxic T-lymphocyte-associated antigen 4 Case report

circRNA landscape of non-pregnant endometrium during the estrus cycle in dairy goats

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Journal of Integrative Agriculture 2021年第5期20卷 1346-1358页

作者： LIU Xiao-rui ZHANG Lei CUI Jiu-zeng YANG Li-chun HAN Jin-cheng che Si-cheng CAO Bin-yun LI Guang SONG Yu-xuan College of Animal Science and Technology Northwest A&F UniversityYangling 712100P.R.China Shaanxi Provincial Key Laboratory of Animal Genetics Breeding and ReproductionCollege of Animal Science and TechnologyNorthwest A&F UniversityYangling 712100P.R.China

Endometrial development is a complicated process involving numerous regulatory *** RNAs(circRNAs)have been known as a member of the naturally occurring non-coding RNA family,and are reportedly crucial for a variety of physiological *** study investigated the circRNA landscape of non-pregnant endometrium of dairy goats during ***-pregnant endometrial samples of goats at estrus day 5(Ed5)and estrus day 15(Ed15)were used to methodically analyze the circRNA landscape using strand-specific Ribo-Zero RNA-Seq.A total of 2331 differentially expressed(P<0.05)circRNAs(DEciRs)between Ed5 and Ed15 were discovered in the goat *** was found that Nipped-B-like(NIPBL)and calcium responsive transcription factor(CARF)may participate in the development of the endometrium by decreasing(P<0.05)the levels of their circRNA-transcript ***,Gene Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analyses of DEciR host genes(hgDEciRs)revealed that tight junctions and GTPases may be involved in endometrial development during the estrus cycle.A total of 2331 DEciRs were discovered in the endometrium at Ed5 and *** on GO and KEGG enrichment analyses,it could be inferred that tight junctions and GTPases are likely to play an important role in the development of goat endometrium during the estrus *** circRNA study greatly enhances our knowledge of global trends in the development of non-pregnant endometrium during the estrus cycle in goats;these results help us to better understand the molecular regulation of endometrial development in dairy goats.

关键词： circRNAs Ribo-Zero RNA-Seq non-pregnant endometrium dairy goats

Process development for producing a food-grade glucose solution from rice straws

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Chinese Journal of chemical Engineering 2018年第2期26卷 386-392页

作者： Chih-Heng Wang Wen-Hua chen Hwai-Shen Liu Jinn-Tsyy Lai cheng-che Hsu Ben-Zu Wan Department of chemical Engineering Norional Taiwan UniversityTaipeiChina Institute of Nuclear Energy Research TaoyuanChina Food Industry Research and Development Institute HsinchuChina

In this paper, processes for producing a food-grade glucose solution through enzymatic hydrolysis of celluloserich solids obtained from rice straws are presented. The rice straws were pretreated by acid-catalyzed steam explosion, and the reaction efficiency, toxicity control, and process economic feasibility were studied. Mass transfer resistance to the hydrolysis reaction was reduced by grinding with glass beads. A higher glucose concentration could be obtained by feeding more cellulose in the hydrolysis reaction; however, this also resulted in the production of undesired byproducts. Thus, a soaking process for the cellulose solids in water was developed to effectively reduce the generation of byproducts in the hydrolysis reaction. The resulting food-grade glucose solution can provide 414 kilocalories per liter, and could be used during a food-shortage crisis in the *** current production cost is estimated to be 0.82 USD·L^(-1).

关键词： Cellulose Enzymatic hydrolysis Food-grade glucose solution Rice straw Biochemical engineering

Enhanced tensile properties and wear resistance of additively manufactured CoCrFeMnNi high-entropy alloy at cryogenic temperature

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Rare Metals 2022年第4期41卷 1210-1216页

作者： Hong-Ge Li Peng-cheng che Xiao-Kun Yang Yong-Jiang Huang Zhi-Liang Ning Jian-Fei Sun Hong-Bo Fan School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China Harbin-Electric Power Generation Equipment National Engineering Research Center Co. LtdHarbin 150028China

Here,bulk CoCrFeMnNi high-entropy alloy was prepared via laser melting deposition,and its microstructure and mechanical properties at room and cryogenic temperature were investigated by a series of microstructural character-izations and mechanical *** results showed that the as-built samples possessed a single fcc phase and highly dense *** to the mechanical prop-erties at room temperature,tensile properties,microhard-ness and wear resistance of the as-built samples showed a signiflcant enhancement at cryogenic temperature,which was attributed to the deformation mechanism converting from dislocation slipping to deformation twinning at cryogenic *** formation of deformation nanotwins signiflcantly improved the deformation resis-tance in cryogenic conditions,and the sliding wear in the liquid nitrogen could decrease the oxygen concentration,suppress the generation of oxide particles and thus enhance the wear resistance.

关键词： wear cryogenic alloy

Microstructures and mechanical properties of laser-directed energy deposited CrCoNi medium-entropy alloy

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Rare Metals 2024年第7期43卷 3286-3300页

作者： Wen-Jie Zhao Chang-Yu Liu Peng-cheng che Zhi-Liang Ning Hong-Bo Fan Jian-Fei Sun Yong-Jiang Huang Alfonso H.W.Ngan National Key Laboratory for Precision Hot Processing of Metals Harbin Institute of TechnologyHarbin 150001China Space Environment Simulation Research Infrastructure Harbin Institute of TechnologyHarbin 150001China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China

The distinctive intrinsic heat treatment(IHT)originating from cyclic reheating in the laser-directed energy deposition(LDED) has attracted growing attention in recent *** this investigation,simulations and experimental characterizations were performed to examine the impact of IHT on the micros true ture and mechanical properties of LDED-fabricated CrCoNi medium-entropy alloy(MEA).The results show that the intensity of the IHT is proportional to the utilized laser energy density(LED).As the LED increased,significant dynamic recrystallization and grain refinement occurred within the alloy due to the enhanced intensity of ***,the high LED leads to severe hot cracking within the as-built MEA,resulting in inferior *** decreasing LED,the hot cracking was effectively ***,low LED weakened the intensity of IHT and consequently inhibited kinetic conditions of dynamic recrystallization,resulting in a heterogeneous grain structure characterized by multi-scale-sized *** structure provides significant hetero-deformation-induced hardening during plastic deformation,enabling the alloy to have a sustainable work-hardening *** expect that this work will have implications in taking full advantage of the unique IHT of the LDED process to fabricate ME As with excellent metallurgical quality and mechanical performance.

关键词： Intrinsic heat treatment Laser-directed energy deposition CrCoNi MEA Dynamic recrystallization Heterogeneous grain structure

ANALYSIS OF PIPE VIBRATIONS WITH INTERNAL FLUID FLOW

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ANALYSIS OF PIPE VIBRATIONS WITH INTERNAL FLUID FLOW

作者： che-Min cheng

IntroductionThis is a study of the problem of small oscillations of a thin cylindrical shell when there is a fluid inside. Interest in this problem arises out of an attempt to interpret the sustained vibration of an actual pipe from a theoretical point of view, and also to provide a theoretical basis upon which methods may be devised to eliminate or minimize undesirable *** the first part of the present investigation, the basic equations governing the motions of the fluid and of the shell are developed under a number of simplifying assumptions. The single

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再生细集料对水泥混凝土物理力学性能的影响

土木建筑与环境工程 2011年第3期33卷 143-146,152页

作者：孙家瑛车乘乘浙江大学宁波理工学院绿色建材与废弃物资源化研究中心宁波315100 上海大学土木工程系上海20072

废弃混凝土通过一系列再生工艺可以得到再生混凝土细集料,将其部分或全部替代天然砂配制混凝土可以达到变废为宝的目的,但是再生混凝土细集料特殊的性质会使得掺再生细集料的混凝土性能与普通混凝土之间存在较大的差异。在研究再生混凝... 详细信息

废弃混凝土通过一系列再生工艺可以得到再生混凝土细集料,将其部分或全部替代天然砂配制混凝土可以达到变废为宝的目的,但是再生混凝土细集料特殊的性质会使得掺再生细集料的混凝土性能与普通混凝土之间存在较大的差异。在研究再生混凝土细集料的粒径和物理特性对水泥混凝土物理力学性能影响的基础上,探讨再生混凝土细集料对混凝土的抗气渗性能、抗氯离子渗透性能、抗碳化性能的影响。研究结果发现,再生细集料在破碎制备过程中产生了大量缺陷和粉料,采用一定量的再生细集料替代天然细集料配制混凝土,其物理力学性能、抗氯离子渗透性能和抗碳化能力均与基准混凝土有明显差异。如再生细集料最小粒径从0.16 mm及以下提高到2.36mm就可以明显改善混凝土物理力学性能。

关键词：再生细集料最小粒径物理力学性能抗气渗性能氯离子渗透性能

Application of Non-Detective Techniques Traditional Masonry Structures

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Journal of Shanghai Jiaotong university(Science) 2013年第3期18卷 306-310页

作者： cheng cheng che Ai-lan CAO Yong-kang School of Naval Architecture Ocean and Civil Engineering Shanghai aiaotong University Shanghai 200240 China

Study on the non-destructive detection techniques and damage identification method is of great importance in protecting and rehabilitating the ancient architectural structure. In order to identify the location and the grade of structural damages, a multi-point microtremor measurement is performed on carved brick screen walls at Songjiang area in Shanghai, and the observed dynamic parameters （natural frequencies and natural modal） are obtained. On the other hand, the dynamic parameters of the original structure are calculated by finite-elementmethod （FEM）. Normalizing tile observed and calculated parameters on unified physical quantity, the damages are located by the variation on vibration modal, and the grade of structural damages is quantitatively evaluated by stiffness losses based on the variation on vibration modal.

关键词： damage identification microtremor natural modal stiffness loss