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Modelling ignition probability with pairwise mixing-reaction model for flame particle tracking

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Chinese Journal of Aeronautics 2021年第5期34卷 523-534页

作者： qing xie Zhuyin REN Ke WANG School of Aerospace Engineering Tsinghua UniversityBeijing 100084China Institute for Aero Engine Tsinghua UniversityBeijing 100084China Aero Engine Academy of China Beijing 101300China

Reduced order models for ignition analysis can offer insights into ignition processes and facilitate the combustor *** this study,a Pairwise Mixing-Reaction(PMR)model is formulated to model the interaction between the flame particle and the surrounding cell mixture during Lagrangian flame particle ***,the model accounts for the two-way coupling of mass and energy between the flame particle and the surrounding shell layer by modelling the corresponding turbulent mixing,chemical reaction and evaporation process if *** state of a flame particle,e.g.,burnt,hot gas or extinguished,is determined based on particle *** model can properly describe the ignition process with a spark kernel being initiated in a nonflammable region,which is of practical importance in certain turbine engines and has not been rigorously accounted for by the existing models based on the estimation of local Karlovitz *** model is integrated into an ignition probability analysis platform and is demonstrated for a methane/air bluff-body flame with the flow and fuel/air mixing characteristics being extracted from a non-reacting *** results show that for the spark location being at the extreme fuellean outer shear layer of the recirculation zone,PMR can yield ignition events with a significant number of active flame *** mechanisms for the survival of the initial flame particles and the entrainment of the survived flame particles into the recirculation zone are *** results also show that the ignition probability map from PMR agrees well with the experimental observation:a high ignition probability in the shear layer of the recirculation zone near the mean stoichiometric surface,and low ignition probabilities inside the recirculation zone and the top stagnation region of the recirculation *** parametric study shows that the predicted shape of the ignition progress factor and ignition probability is in general inse

关键词： Bluff-body stabilized flame Igniting process Ignition probability Lagrangian particle tracking Pairwise mixing-reaction

Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD) and Viral Hepatitis

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Journal of Clinical and Translational Hepatology 2022年第1期10卷 128-133页

作者： Xiaolin Wang qing xie Department of Infectious Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

A new definition of metabolic dysfunction-associated fatty liver disease(MAFLD)was proposed in *** change from nonalcoholic fatty liver disease(NAFLD)to MAFLD highlights the metabolic abnormalities that accompany fatty *** diagnosis of MAFLD does not require exclusion of secondary causes of liver diseases and alcohol ***,MAFLD may coexist with other types of liver diseases,such as viral hepatitis,a disease that remains the most common cause of liver disease-related *** the increasing prevalence of MAFLD,patients with coincidental MAFLD and viral hepatitis are frequently encountered in clinical *** this review,we mainly summarize the mutual relationship between hepatitis B/C and systematic metabolism dysfunction related to *** discuss the impact of MAFLD on progression of viral hepatitis and the *** unaddressed clinical problems related to concomitant MAFLD and viral hepatitis are also identified.

关键词： Metabolic dysfunction-associated fatty liver disease Chronic hepatitis B Chronic hepatitis C

New types of topological superconductors under local magnetic symmetries

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National Science Review 2021年第5期8卷 85-90页

作者： Jinyu Zou qing xie Zhida Song Gang Xu Wuhan National High Magnetic Field Center & School of Physics Huazhong University of Science and Technology Department of Physics Princeton University

We classify gapped topological superconducting(TSC) phases of one-dimensional quantum wires with local magnetic symmetries, in which the time-reversal symmetry T is broken, but its combinations with certain crystalline symmetries, such as MxT, C2zT, C4zT and C6zT, are preserved. Our results demonstrate that an equivalent BDI class TSC can be realized in the MxT or C2zT superconducting wire,which is characterized by a chiral Zcinvariant. More interestingly, we also find two types of totally new TSC phases in the C4zT and C6zT superinducting wires, which are beyond the known AZ class, and are characterized by a helical Z~h invariant and Z~h ⊕Zcinvariants, respectively. In the Z~h TSC phase, Z pairs of Majorana zero modes(MZMs) are protected at each end. In the C6zT case, the MZMs can be either chiral or helical, and even helical-chiral coexisting. The minimal models preserving C4zT or C6zT symmetry are presented to illustrate their novel TSC properties and MZMs.

关键词： topological superconductor magnetic symmetry Majorana zero mode superconducting wire

Effecacy of Biejia(Carapax Trionycis) and Ezhu(Rhizoma Curcumae Phaeocaulis) couplet medicine on epithelial-mesenchymal transition, invasion and migration of MDA-MB-231 triple negative breast cancer cells via PI3K/Akt/mTOR signaling pathway

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Journal of Traditional Chinese Medicine 2021年第6期41卷 853-861页

作者： ZHU Manjing xie Su xie qing ZHU Jiulong HUANG Yazhen Guizhou Medical University Guiyang 550004China the Affiliated Hospital of Guizhou Medical University Guiyang 550004China

OBJECTIVE:To investigate the efficacy of Biejia(Carapax Trionycis)and Ezhu(Rhizoma Curcumae Phaeocaulis)couplet medicine on epithelial-mesenchymal transition(EMT),invasion and migration of MDA-MB-231 triple negative breast cancer(TNBC)cells based on PI3K/Akt/mTOR signaling ***:MDA-MB-231 cells were treated with different medicated serum as Biejia-,Ezhu-,Biejia-Ezhu(BJ-,EZ-,BJ-EZ-)groups,intervened with no drug rat serum and paclitaxel with final concentration of 33 nM(IC50)as negative and positive control(NC and PC)***-8 assay,scratch test,and Transwell assay were used to examine cell proliferation,invasion,and *** expression of E-cadherin,N-cadherin,Vimentin,MMP-2,MMP-9,PI3K,Akt,p-Akt,mTOR,and p-mTOR was determined by Western blot,and the m RNA expression of PI3K,Akt and mTOR was determined by real-time polymerase chain ***:BJ-EZ group inhibited proliferation after 24,48,and 72 h compared with the NC group(P<0.05,<0.01 or<0.001)and reduced the invasion and migration of MDA-MB-231 cells(P<0.01 or<0.001).In addition,BJ-EZ group upregulated the expression of E-cadherin,downregulated the expression of N-cadherin,Vimentin,MMP-2,and MMP-9(P<0.05,P<0.01 or P<0.001),and inhibited the m RNA and protein expression of PI3K,Akt(p-Akt),mTOR(p-mTOR)(P<0.05,<0.01 or<0.001).CONCLUSION:Biejia(Carapax Trionycis)and Ezhu(Rhizoma Curcumae Phaeocaulis)couplet medicine can inhibit the proliferation,invasion,migration and EMT of MDA-MB-231 cells through PI3K/Akt/mTOR signaling pathway,and the effect is better than that of Biejia(Carapax Trionycis)or Ezhu(Rhizoma Curcumae Phaeocaulis)alone.

关键词： triple negative breast neoplasms epithelial-mesenchymal transition PI3K/Akt/mTOR signal transduction Biejia(Carapax Trionycis) Ezhu(Rhizoma Curcumae Phaeocaulis)

Influence characteristics of water penetration on fibre-reinforced polymer/rigid polyurethane foam interface of the composite cross-arm considering natural ageing

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High Voltage 2024年第1期9卷 81-93页

作者： Jun xie Zhe Zhou Ziqian Liu Haonan Tian Sigang Zhang qing xie Hebei Provincial Key Laboratory of Power Transmission Equipment Security Defense North China Electric Power UniversityBaodingChina State Grid Gansu Electric Power Company LanzhouChina

Fibre-reinforced polymer(FRP)/rigid polyurethane foam(RPUF)interface is susceptible to moisture intrusion in addition to natural ageing during *** study investigated the influence of moisture intrusion on the FRP/RPUF interface under natural ageing using experiments and molecular dynamics(MD)*** absorption,shear strength,and leakage current tests were used to clarify the changes in the interface *** degradation mechanism of moisture intrusion at the interface under natural ageing was revealed by MD simulation and *** results show that the natural ageing of interfacial materials will slightly reduce the quality of the interface but will reduce the water resistance of the material and promote the process of water intrusion into the *** addition,water mainly invades the interface through *** water penetration,the interfacial bonding strength and insulation performance significantly *** and hydrolysis of interfacial materials are the main reasons for decreased interfacial *** can cause irreversible damage to the interface,increasing interface defects and water *** vicious cycle of material hydrolysis is the ultimate cause of interfacial *** polar molecules produced by this process and the water absorbed by the interface caused the degradation of the interface insulation performance.

关键词： interface polyurethane interfacial

A Robust Discontinuous Galerkin Method for Solving Convection-diffusion Problems

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Acta Mathematicae Applicatae Sinica 2008年第3期24卷 483-496页

作者： Zuo-zheng Zhang Zi-qing xie Xia Tao College of Mathematics and Computer Science Hunan Normal University Changsha 410081 China

In this paper, a new DG method was designed to solve the model problem of the one-dimensional singularly-perturbed convection-diffusion equation. With some special chosen numerical traces, the existence and uniqueness of the DG solution is provided. The superconvergent points inside each element are observed. Particularly, the 2p ＋ 1-order superconvergence and even uniform superconvergence under layer-adapted mesh are observed numerically.

关键词： Discontinuous Galerkin method singularly perturbed convection-diffusion numerical traces

Combined effect of repetitive transcranial magnetic stimulation and physical exercise on cortical plasticity

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Neural Regeneration Research 2020年第11期15卷 1986-1994页

作者： Ya-Wen Yang Wen-Xiu Pan qing xie Department of Rehabilitation Medicine Ruijin HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina Department of Rehabilitation Medicine Shanghai Ruijin Rehabilitation HospitalShanghaiChina

Physical exercise can minimize dysfunction and optimize functional motor recovery after stroke by modulating cortical ***,the limitation of physical exercise is that large amounts of time and effort are necessary to significantly improve motor function,and even then,substantial exercise may not be sufficient to normalize the observed ***,interventions that could be used to strengthen physical exercise-induced neuroplasticity may be valuable in treating hemiplegia after *** transcranial magnetic stimulation seems to be a viable strategy for enhancing such *** a non-invasive cortical stimulation technique,repetitive transcranial magnetic stimulation is able to induce longterm plastic changes in the motor ***,repetitive transcranial magnetic stimulation was found to optimize the plastic changes caused by motor training,thereby enhancing the long-term effects of physical exercise in stroke ***,it is believed that the combination of repetitive transcranial magnetic stimulation and physical exercise may represent a superior method for restoring motor function after stroke.

关键词： functional recovery motor cortex neuroplasticity physical exercise primary motor cortex repetitive transcranial magnetic stimulation stroke

A Superhydrophobic/Electrothermal/Photothermal Synergistically Anti-icing Strategy with Excellent Self-healable and Anti-abrasion Property

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Journal of Bionic Engineering 2021年第5期18卷 1147-1156页

作者： Peng Wang Jian Wang Wei Duan Chunyan Li Huilong Han qing xie School of Energy Power and Mechanical EngineeringNorth China Electric Power UniversityBaodingChina Hebei Key Laboratory of Electric Machinery Health Maintenance and Failure Prevention North China Electric Power UniversityBaoding 071003China School of Electrical and Electronic Engineering North China Electric Power UniversityBaodingHebeiChina

Unexpected ice accumulation tends to cause many problems or even disasters in our daily *** on the superior electrothermal and photothermal function of the carbon nanotubes,we introduced a superhydrophobic/electrothermal/photothermal synergistically anti-icing *** a voltage of 15 V was applied to the superhydrophobic sample,the surface could rapidly melt the ice layer(~3 mm thickness)within 530 s at the environmental temperature of-25℃.When the near-infrared light(808 nm)irradiates on the superhydrophobic sample,the ice could be rapidly removed after 460 *** was found that the superhydrophobicity helps the melted water to roll off immediately,and then solves the re-freeze problem the traditional surfaces ***,the ice can be completely melted with 120 s when the superhydrophobic/electrothermal/photothermal synergistically anti-icing strategy was *** improve the mechanical robustness for practical application,both nanoscale carbon nanotubes and microscale carbon powders were utilized to construct hierarchical *** these dual-scale fillers were sprinkled onto the semi-cured elastomer substrate to prepare partially embedded *** hierarchical structure and partially embedded structure were obtained after completely curing the substrate,which imparts excellent abrasion resistance(12.50 kPa,16.00 m)to the prepared ***,self-healable poly(urea–urethane)elastomer was introduced as the ***,the cutted superhydrophobic sample can be mended by simply contacting at room temperature.

关键词： Superhydrophobic Electrothermal Photothermal Self-healing

Flow field, heat transfer and inclusion behavior in a round bloom mold under effect of a swirling flow submerged entry nozzle

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Journal of Iron and Steel Research International 2023年第6期30卷 1211-1221页

作者： qing-hua xie Pei-yuan Ni Toshihiro Tanaka Mikael Ersson Ying Li Key Laboratory of Ecological Metallurgy of Multi-metal Intergrown Ores of Ministry of Education School of MetallurgyNortheastern UniversityShenyang 110819LiaoningChina Liaoning Key Laboratory of Metallurgical Sensor Materials and Technology School of MetallurgyNortheastern UniversityShenyang 110819LiaoningChina Graduate School of Engineering Osaka UniversityOsaka 565-0871Japan Department of Materials Science and Engineering KTH Royal Institute of TechnologyStockholm 10044Sweden

Flow field,heat transfer and inclusion behavior in a 700 mm round bloom mold under the effect of a swirling flow submerged entry nozzle(SEN)were investigated with the aim to enhance the casting *** results indicate that the impinging flow phenomenon,which is commonly observed in conventional single-port SEN casting,was completely suppressed by the swirling flow SEN coming from a novel swirling flow generator design in *** from the SEN port moved towards the mold wall in 360 direction,leading to a uniform temperature distribution in the *** to a conventional single-port SEN casting,the steel super-heat was decreased by about 5 K at the mold center,and the temperature was increased by around 3.5 K near the *** addition,the removal ratio of inclusions to the mold top surface in the swirling flow SEN casting was found to be ***,the removal ratio of spherical inclusions with diameters of 1,10,50 and 100μm was increased by 18.2%,18.5%,22.6% and 42.7%,***,the ratio was raised by 18.2%,20.8%,21.5% and 44.1%for non-spherical inclusions,respectively.

关键词： Large round bloom Swirling flow submerged entry nozzle casting Flow field Heat transfer Inclusion behavior