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Therapeutic effect of Wendan Decoction combined with mosapride on gastroesophageal reflux disease after esophageal cancer surgery

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World Journal of Clinical Cases 2024年第13期12卷 2194-2200页

作者： Yu-Jing Zhang Shen-ping wu Department of Oncology Beijing Integrated Traditional Chinese and Western Medicine HospitalBeijing 100039China

BACKGROUND Gastroesophageal reflux disease(GERD)is a common complication of esophageal cancer surgery that can affect quality of life and increase the risk of esophageal stricture and anastomotic *** Decoction(WDD)is a traditional Chinese herbal formula used to treat various gastrointestinal disorders,such as gastritis,functional dyspepsia,and irritable bowel ***,a prokinetic agent,functions as a selective 5-hydroxytryptamine 4 agonist,enhancing gastrointestinal *** To evaluate the therapeutic effects of WDD combined with mosapride on GERD after esophageal cancer *** Eighty patients with GERD were randomly divided into treatment(receiving WDD combined with mosapride)and control(receiving mosapride alone)*** treatment was conducted from January 2021 to January *** primary outcome was improved GERD symptoms as measured using the reflux disease questionnaire(RDQ).The secondary outcomes were improved esophageal motility(measured using esophageal manometry),gastric emptying(measured using gastric scintigraphy),and quality of life[measured via the Short Form-36(SF-36)Health Survey].RESULTS The treatment group showed a notably reduced RDQ score and improved esophageal motility parameters,such as lower esophageal sphincter pressure,peristaltic amplitude,and peristaltic velocity compared to the control *** treatment group showed significantly higher gastric emptying rates and SF-36 scores(in both physical and mental domains)compared to the control *** serious adverse effects were observed in either *** WDD combined with mosapride is an effective and safe therapy for GERD after esophageal cancer *** can improve GERD symptoms,esophageal motility,gastric emptying,and the quality of life of *** studies with larger sample sizes and longer follow-up periods are required to confirm these findings.

关键词： Gastroesophageal reflux disease Esophageal cancer surgery Wendan Decoction Mosapride Treatment effects Gastroesophageal reflux disease symptoms

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Dietary inflammatory index and its impact on severity and recurrence of Tourette syndrome in children

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World Journal of Psychiatry 2024年第8期14卷 1208-1215页

作者： Xiao-ping wu Rong-Rong Fang Ting-Ting Ji Department of Pediatrics Qingdao Chengyang People’s HospitalQingdao 266109Shandong ProvinceChina

BACKGROUND Tourette syndrome(TS)is a neurodevelopmental disorder characterized by the presence of motor and vocal tics,typically beginning in *** signifi-cant research efforts,the exact pathophysiology of TS remains incompletely *** studies suggest that inflammation may play a role in the severity and progression of TS,pointing to the potential influence of dietary and lifestyle factors on the ***,research on the specific connection between dietary inflammatory index(DII)and TS is still in its early stages,requir-ing additional clinical and epidemiological studies to validate the strength and specific mechanisms of this *** A total of 207 children diagnosed with TS in the pediatric department of Qingdao Chengyang People’s Hospital from January 2022 to January 2023 were *** were divided into stable and unstable groups based on follow-up *** enrollment,general information of the children[age,gender,body mass index(BMI),guardian’s education level,DII score,medical history,family history,academic stress,electronic device usage,medication,and disease progression]was assessed,and serum inflammatory levels were measured during follow-up *** scores and Yale Global Tic Severity Scale(YGTSS)scores were ***,based on YGTSS scores,the children were classified into mild,moderate,and severe *** DII,interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-alpha(TNF-α)levels in each group were *** Follow-up surveys were completed by 207 children and their *** them,117 children were in the stable group,and 90 were in the recurrent *** found no statistically significant differences in age,gender,comorbidities,BMI,and disease duration between the two groups(P>0.05).However,academic stress,electronic device usage,medication,guardian’s education level,and DII scores showed statistically significant differences between the groups(P

关键词： Dietary inflammation index Tourette's syndrome Correlation analysis Pro-inflammatory foods Inflammation levels Impact on severity and recurrence

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Exploring the Applications of Digital Twin Technology in Enhancing Sustainability in Civil Engineering:A Review

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Structural Durability & Health Monitoring 2024年第5期18卷 577-598页

作者： Jiamin Huang ping wu Wangxin Li Jun Zhang Yidong Xu School of Civil Engineering Chongqing Jiaotong UniversityChongqing400074China School of Civil Engineering and Architecture NingboTech UniversityNingbo315100China School of Civil Engineering Lanzhou University of TechnologyLanzhou730050China

With the advent of the big data era and the rise of Industrial Revolution 4.0,digital twins(DTs)have gained sig-niﬁcant attention in various *** offer the opportunity to combine the physical and digital worlds and aid the digital transformation of the civil engineering *** this paper,605 documents obtained from the search wereﬁrst analysed using CiteSpace for literature visualisation,and an author co-occurrence network,a keyword co-occurrence network,and a keyword clustering set were ***,through a literature review of 86 papers,this paper summarises the current status of DT application in civil engineering based on a review of the origins,concepts,and implementation techniques of DTs,and it introduces the application of DTs in the full project *** study shows that DTs have great potential to address many of the challenges faced by civil *** this regard,the paper also presents some thoughts on the future directions of DT research.

关键词： Digital twins civil engineering full lifecycle literature visualisation analysis

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Event-Triggered Fixed-Time Consensus of Second-Order Nonlinear Multi-Agent Systems with Delay and Switching Topologies

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Journal of Shanghai Jiaotong university(Science) 2024年第4期29卷 625-639页

作者： XING Youjing GAO Jinfeng LIU Xiaoping wu ping School of Information Science and Engineering Zhejiang Sci-Tech UniversityHangzhou310018China Department of Systems and Computer Engineering Carleton UniversityOttawaK1S 5B6Canada

To address fixed-time consensus problems of a class of leader-follower second-order nonlinear multi-agent systems with uncertain external disturbances,the event-triggered fixed-time consensus protocol is ***,the virtual velocity is designed based on the backstepping control method to achieve the system consensus and the bound on convergence time only depending on the system ***,an event-triggered mechanism is presented to solve the problem of frequent communication between agents,and triggered condition based on state information is given for each *** is available to save communication resources,and the Zeno behaviors are ***,the delay and switching topologies of the system are also ***,the system stabilization is analyzed by Lyapunov stability ***,simulation results demonstrate the validity of the presented method.

关键词： event-triggered mechanism fixed-time consensus multi-agent systems switching topologies

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Amphipathic Janus Nanofibers Aerogel for Efficient Solar Steam Generation

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Energy & Environmental Materials 2024年第4期7卷 422-432页

作者： Rui Wang Jinshuo Deng ping wu Qianli Ma Xiangting Dong Wensheng Yu Guixia Liu Jinxian Wang Lei Liu Chongqing Research Institute Changchun University of Science and Technology Key Laboratory of Applied Chemistry and Nanotechnology at Universities of Jilin Province Changchun University of Science and Technology

Solar steam generation is a promising water purification technology due to its low-cost and environmentally friendly applications in water purification and ***,hydrophilic or hydrophobic materials alone are insufficient in achieving necessary characteristics for constructing highquality solar steam generators with good comprehensive properties.

关键词： aerogels electrospinning photothermal materials solar desalination solar steam generation

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Dynamic modulation of nodulation factor receptor levels by phosphorylation-mediated functional switch of a RING-type E3 ligase during legume nodulation

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Molecular Plant 2024年第7期17卷 1090-1109页

作者： Hao Li Yajuan Ou Jidan Zhang Kui Huang ping wu Xiaoli Guo Hui Zhu Yangrong Cao National Key Lab of Agricultural Microbiology Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China National Key Lab of Agricultural Microbiology College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China

The precise control of receptor levels is crucial for initiating cellular signaling transduction in response to specific ligands;however,such mechanisms regulating nodulation factor(NF)receptor(NFR)-mediated perception of NFs to establish symbiosis remain *** this study,we unveil the pivotal role of the NFR-interacting RING-type E3 ligase 1(NIRE1)in regulating NFR1/NFR5 homeostasis to optimize rhizobial infection and nodule development in Lotus *** demonstrated that NiRE1 has a dual function in this regulatory *** associates with both NFR1 and NFR5,facilitating their degradation through K48-linked polyubiquitination before rhizobial ***,following rhizobial inoculation,NFR1 phosphorylates NIRE1ata conserved residue,Tyr-109,inducing a functional switch in NIRE1,which enables NIRE1tomediateK63-linkedpolyubiquitination,thereby stabilizing NFR1/NFR5 in infected root *** introduction of phospho-dead NIRE1Y1osF leads to delayed nodule development,underscoring the significance of phosphorylation at Tyr-1o9 in orchestrating symbiotic ***,expression of the phospho-mimic NIRE1Y0E results in the formation of spontaneous nodules in ***,further emphasizing the critical role of the phosphorylation-dependent functional switch in *** summary,these findings uncover a fine-tuned symbiotic mechanism that a single E3 ligase could undergo a phosphorylationdependent functional switch to dynamically and precisely regulate NF receptor protein levels.

关键词： nodule symbiosis nodulation factor receptors E3 ligase ubiquitination phosphorylation protein degradation protein stabilization Lotus japonicus

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Predictors of Adverse Pregnancy Outcomes Following Traumatic Injuries

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Current Medical Science 2024年第3期44卷 642-647页

作者： Wan-rong LU ping wu Gong SONG Mei-qi GU Zhe XU Li HE National Clinical Research Center for Gynecology and Obstetrics Cancer Biology Research CenterTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Traumatic Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

Objective After traumatic injury in pregnant women,providing timely and appropriate management for high-risk patients is crucial for both pregnant women and *** study aimed to identify risk factors that predict adverse pregnancy outcomes after traumatic *** A retrospective cohort study including 317 pregnant patients who experienced trauma was *** collected data included general demographics,injury mechanisms and adverse pregnancy *** were divided into two subgroups based on the absence or presence of trauma-related adverse pregnancy *** and multivariate logistic regressions were conducted to estimate the associations between clinical variables and adverse pregnancy *** A total of 41(12.93%)patients experienced adverse pregnancy outcomes within the first 24 h *** study revealed that age>35 years(OR=14.995,95%CI:5.024–44.755,P<0.001),third trimester trauma(OR=3.878,95%CI:1.343–11.204,P=0.012),abdominal pain(OR=3.032,95%CI:1.221–7.527,P=0.017),vaginal bleeding(OR=3.226,95%CI:1.093–9.523,P=0.034),positive scan in focused assessment with sonography for trauma(FAST)positive(OR=8.496,95%CI:2.825–25.555,P<0.001),9≤injury severity score(ISS)<16(OR=3.039,95%CI:1.046–8.835,P=0.041)and ISS≥16(OR=5.553,95%CI:1.387–22.225,P=0.015)increased the probability of posttraumatic adverse pregnancy *** age,gestational age at delivery,vaginal bleeding and positive FAST results were risk factors for abnormal *** Advanced maternal age,third trimester,and positive FAST results should alert multidisciplinary trauma teams to closely monitor patients to prevent adverse pregnancy outcomes.

关键词： adverse pregnancy outcomes predictive factors abnormal delivery trauma

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Analysis on the causes of massive stranding of Yellow Sea green tide on Lianyungang and Rizhao coasts in 2022

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Journal of Oceanology and Limnology 2024年第3期42卷 816-830页

作者： Lingjuan wu Juan HUANG Yi DING Guiyan LIU Shuai HUANG Song GAO Chao YUAN Jiangling XU ping wu Rui HUANG Ruobing WEN Jie MEI North China Sea Marine Forecasting and Hazard Mitigation Center Ministry of Natural ResourcesQingdao 266061China Shandong Key Laboratory of Marine Ecological Environment and Disaster Prevention and Mitigation Qingdao 266061China National Engineering Laboratory for Integrated Aero-Space-Ground-Ocean Big Data Application Technology Xi’an 710129China East China Sea Marine Forecasting and Hazard Mitigation Center Ministry of Natural ResourcesShanghai 200136China North China Sea Ecological Center Ministry of Natural ResourcesQingdao 266033China

In 2022,Yellow Sea green tide caused by Ulva prolifera reached a historic minimum and the coastal areas of Shandong Peninsula were less ***,the largest amount of seaweed biomass has been washed ashore on Lianyungang and Rizhao coasts since *** studied the development pattern of Yellow Sea green tide in 2022,and analyzed the key environmental factors on the growth and drifting,then discussed the possible reasons that resulted in the massive stranding of green tide biomass in Lianyungang and *** show under the combined influence of the east to southeast winds and currents with shoreward anomalies,green tide drifted to the coastal waters between Shandong and Jiangsu provinces and the distribution areas located westward compared with previous years(2008–2021).Floating *** rafts from the coastal waters of Binhai and Sheyang drifted continuously into the coastal waters of Lianyungang and Rizhao,providing important supplements for Yellow Sea green *** green tide in 2022 distributed close to the coastal waters,the abundant nutrients might support their continuous high growth *** addition,the amount of rainfall around Shandong Peninsula from late June to early July were significantly higher than in previous years,which might promote the development of green tide to some extent.

关键词： Yellow Sea green tide stranding biomass development pattern environmental factor

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Introduction of rare-earth element Sc in alloy design to modify wear features of dual-phase high-entropy alloy

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Rare Metals 2024年第2期43卷 817-828页

作者： Hao Ren Rui-Run Chen Xue-Feng Gao Tong Liu Gang Qin Yu-Lung Chiu Shi-ping wu Jing-Jie Guo Guo National Key Laboratory for Precision Hot Processing of Metals School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin150001China School of Metallurgy and Materials University of BirminghamBirminghamB152TTUK

Tailoring the alloy composition,which induces the hard secondary phase to increase hardness and strength to improve the wear features,is a feasible approach for developing wear-resistant metal ***,a group of(AlCoCrFeNi)_(100–x)Sc_(x)(x=0–2.0,at%)high-entropy alloys(HEAs)are designed and the phase compositions and wear behaviors are ***-doped HEA series contain the primary body-centered cubic(BCC)and eutectic phases,in which the eutectic phase is composed of the alternately grown BCC and Laves *** addition promotes the diffusion of Ni atoms from BCC phase to form the Sc-rich Laves phase at the grain *** hardness increases due to solid solution strengthening and second phase *** the second phase strengthening plays a more significant role relative to solid solution *** phase and the oxides caused by wear heating prevent the direct contact between friction pair and HEAs,thus inducing a decreased wear rate from 6.82×10^(−5) to 3.47×10^(−5)m^(3)·N^(−1)·m^(−1).Moreover,the wear mechanism changes from adhesive wear,abrasive wear and oxidative wear to abrasive wear and oxidative wear.

关键词： High entropy alloy(HEA) Laves phase Hardness Wear mechanism

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A Hf-doped dual-phase high-entropy alloy: phase evolution and wear features

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Rare Metals 2024年第1期43卷 324-333页

作者： Hao Ren Rui-Run Chen Xue-Feng Gao Tong Liu Gang Qin Yu-Lung Chiu Shi-ping wu Jing-Jie Guo National Key Laboratory for Precision Hot Processing of Metals School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150001China School of Metallurgy and Materials University of BirminghamEdgbastonBirmingham B152TTUK

Initially defined high entropy alloys(HEAs)usually exhibit a single-phase solid-solution ***,two and/or more types of phases in HE As possibly induce the desired microstructure features,which contribute to improving the wear properties of HE ***,we prepare a series of(AlCoCrFeNi)_(100-x)Hf_(x)(x=0,2,4and 6;at%) HEAs and concern their phase compositions,micro structures and wear *** leads to the formation of(Ni,Co)_(2)Hf-type Laves phase and tailors the microstructure from a body-centered cubic(BCC) singlephase structure to a hypoeutectic *** increased hardness from~HV 512.3 to~HV 734.1 is due to solid-solution strengthening,grain refinement strengthening and precipitated phase *** a few oxides(Al_(2)O_(3)+Cr_(2)O_(3)) caused by the wear heating contribute to an 85.5% decrease in wear rate of the HEA system from6.71×10^(-5) to 0.97×10^(-5) m^(3)·N^(-1)·m^(-1).In addition,Hf addition changes the wear mechanism from abrasive wear,mild oxidative wear and adhesive wear to oxidative wear and adhesive wear.

关键词： High entropy alloy Laves phase Hardness Wear mechanism

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