检索结果-南通市图书馆

糖尿病酮症酸中毒和高血糖高渗综合征:成人急性失代偿性糖尿病

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

英国医学杂志中文版 2020年第11期23卷 654-667页

作者： Esra Karslioglu French amy C Donihi Mary t Korytkowski 邓子玄(译) 陆静毅(校) Division of Endocrinology and Metabolism Department of MedicineUniversity of PittsburghPittsburghPAUSA University of Pittsburgh School of Pharmacy PittsburghPAUSA 上海交通大学附属第六人民医院内分泌代谢科

糖尿病酮症酸中毒和高渗性高血糖状态(HHS)是威胁糖尿病患者生命的严重并发症。除了及时发现诱因外,处理这些疾病的第一步包括积极给予静脉输液并适当地补充电解质(主要是钾)。对于糖尿病酮症酸中毒的患者,在积极补液的前提下还需要通... 详细信息

糖尿病酮症酸中毒和高渗性高血糖状态(HHS)是威胁糖尿病患者生命的严重并发症。除了及时发现诱因外,处理这些疾病的第一步包括积极给予静脉输液并适当地补充电解质(主要是钾)。对于糖尿病酮症酸中毒的患者,在积极补液的前提下还需要通过静脉输注胰岛素直至酮症缓解;轻症患者亦可通过皮下途径给予胰岛素。糖尿病酮症酸中毒和HHS的治疗过程中需要有经验的医生进行仔细监测。治疗中常见的问题包括过早终止静脉胰岛素治疗,以及停止静脉使用胰岛素前皮下胰岛素注射次数及剂量不足。本文对糖尿病酮症酸中毒和HHS的急性处理、并发症以及预防复发的相关建议进行了综述,同时就患者在急性期过后仍具有较高再入院、不良事件及死亡风险的原因进行了讨论。

关键词：糖尿病酮症酸中毒预防复发轻症患者死亡风险静脉输注静脉输液再入院高血糖高渗综合征

中国珠江三角洲地区复合基-塘系统的新进展:生态学意义

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

AMBIO－人类环境杂志 1999年第6期28卷 531-535页

作者： amy Wong Chor Yee 闵庆文 the Hong Kong Institute of Education Department of Social Sciences 10 Lo Ping Road Taipo N.T. Hong Kong 中国科学院

珠江三角洲地区的基-塘农-渔业生产形式已经有数百年的历史,但现在那里的环境正在发生着急剧变化。经济改革之后,环境的严重退化已经使农-渔业生产结构、空间格局和农业生物品种发生了很大改变,特别是在顺德市和南海市。80年代后期,池... 详细信息

珠江三角洲地区的基-塘农-渔业生产形式已经有数百年的历史,但现在那里的环境正在发生着急剧变化。经济改革之后,环境的严重退化已经使农-渔业生产结构、空间格局和农业生物品种发生了很大改变,特别是在顺德市和南海市。80年代后期,池塘饲养的传统家鱼养殖数量的下降,出现了更为复杂的、集约化的单一品种的养殖。面向市场的、经济价值较高的单一品种养殖系统,主要是通过扩大池塘面积,来增加产值,以牺牲生态效益为代价促进了经济的发展。本研究考察了1984～1994年基-塘面积比率的变化,并提出了关于新型的单一养殖系统的可持续性问题。

关键词：珠江三角洲地区复合基-塘系统农业生态中国

CD28 ligation increases macrophage suppression of t-cell proliferation

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2012年第4期9卷 341-349页

作者： Daniel Silberman Amanda Bucknum thomas Bartlett Gabriella Composto Megan Kozlowskil Amanda Walker amy Werda Jackelyn Cua Arlene H Sharpe John E Somerville James E Riggs Department of Biology Rider University Lawrenceville NJ 08648 USA Department of Pathology Harvard Medical School Cambridge MA 02115 USA Immunosciences Bristol-Myers Squibb Princeton NJ 08543 USA

When compared to spleen or lymph node cells, resident peritoneal cavity cells respond poorly to t-cell activation in vitro. the greater proportional representation of macrophages in this cell source has been shown to actively suppress the t-cell response. Peritoneal macrophages exhibit an immature phenotype （MHC class IIlo, B7lo） that reduces their efficacy as antigen-presenting cells. Furthermore, these cells readily express inducible nitric oxide synthase （iNOS）, an enzyme that promotes t-cell tolerance by catabolism of the limiting amino acid arginine. Here, we investigate the ability of exogenous t-cell costimulation to recover the peritoneal t-cell response. We show that CD28 ligation failed to recover the peritoneal t-cell response and actually suppressed responses that had been recovered by inhibiting iNOS. As indicated by cytokine ELISpot and neutralizing monoclonal antibody （mAb） treatment, this ＇cosuppression＇ response was due to CD28 ligation increasing the number of interferon （IFN）-y-secreting cells. Our results illustrate that cellular composition and cytokine milieu influence t-cell costimulation biology.

关键词： CD28 costimulation macrophages suppression

Applications and potentials of nanopore sequencing in the(epi)genome and(epi)transcriptome era

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

the Innovation 2021年第4期2卷 11-26页

作者： Shangqian Xie amy Wing-Sze Leung Zhenxian Zheng Dake Zhang Chuanle Xiao Ruibang Luo Ming Luo Shoudong Zhang Key Laboratory of Ministry of Education for Genetics and Germplasm Innovation of tropical Special trees and Ornamental Plants College of ForestryHainan UniversityHaikou 570228China Department of Computer Science The University of Hong KongHong Kong 999077China Beijing Advanced Innovation Centre for Biomedical Engineering Key Laboratory for Biomechanics and Mechanobiology of Ministry of EducationSchool of Biological Science and Medical EngineeringBeihang UniversityBeijing 100083China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CentreSun Yat-sen UniversityGuangzhou 510060China Agriculture and Biotechnology Research Center Guangdong Provincial Key Laboratory of Applied BotanyCenter of Economic BotanyCore Botanical GardensSouth China Botanical GardenChinese Academy of SciencesGuangzhou 510650China School of Life Sciences The Chinese University of Hong KongShatinHong Kong 999077China Center for Soybean Research of the State Key Laboratory of Agrobiotechnology The Chinese University of Hong KongShatinHong Kong 999077China

the Human Genome Project opened an era of(epi)genomic research,and also provided a platform for the development of new sequencing *** and after the project,several sequencing technologies continue to dominate nucleic acid sequencing ***,Illumina(short-read),PacBio(long-read),and Oxford Nanopore(longread)are the most popular sequencing *** PacBio or the popular short-read sequencers before it,which,as examples of the second or so-called Next-Generation Sequencing platforms,need to synthesize when sequencing,nanopore technology directly sequences native DNA and RNA *** sequencing,therefore,avoids converting mRNA into cDNA molecules,which not only allows for the sequencing of extremely long native DNA and full-length RNA molecules but also document modifications that have been made to those native DNA or RNA *** this review on direct DNA sequencing and direct RNA sequencing using Oxford Nanopore technology,we focus on their development and application achievements,discussing their challenges and future *** also address the problems researchers may encounter applying these approaches in their research topics,and how to resolve them.

关键词： nanopore sequencing direct DNA sequencing direct RNA sequencing base modification base-calling long-read sequencing tools and algorithms

RFLP tagging of a Gene Pm12 for Powdery Mildew Resistance in Wheat (triticum aestivum L. )

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 1994年第5期37卷 531-537页

作者：贾继增 t.E.Miller S.M.Reader M.D.Gale Institute of Crop Germplasm Resources CAAS Beijing 100081 PRC Cambridge Laboratory Norwich NR4 7UJUK

A dominant gene, Pml2, conferring the resistance to powdery mildew (Erysiphe graminis) has been transferred to wheat from Aegilops speltoides. Sixteen RFLP probes were used to test Line 31 and its parents, showing that Line 31 is a 6B/6S translocation lines. the linkage analysis by five probes indicates that Pm12 is located on the chromosome 6B/6S, and tightly flanked by an RFLP marker α-amy-1 (1.1 cM), identified by RFLP and isozyme analysis. this approach is equally applicable to the identification of other transferred alien genes and the segments of alien chromosome introgressed into wheat.

关键词： wheat powdery mildew resistance RFLP linkage.

SWAt Model Prediction of Phosphorus Loading in a South Carolina Karst Watershed with a Downstream Embayment

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Protection 2013年第7期4卷 75-90页

作者： Devendra M. Amatya Manoj K. Jha thomas M. Williams amy E. Edwards Daniel R. Hitchcock Baruch Institute of Coastal Ecology and Forest Science Clemson University Georgetown USA Center for Forested Wetlands Research USDA Forest Service Cordesville USA Department of Civil Architectural and Environmental Engineering North Carolina A&T University Greensboro USA Florida A&M University Tallahassee USA.

the SWAt model was used to predict total phosphorus (tP) loadings for a 1555-ha karst watershed—Chapel Branch Creek (CBC)—which drains to a lake via a reservoir-like embayment (R-E). the model was first tested for monthly streamflow predictions from tributaries draining three potential source areas as well as the downstream R-E, followed by tP loadings using data collected March 2007-October 2009. Source areas included 1) a golf course that received applied wastewater, 2) urban areas, highway, and some agricultural lands, and 3) a cave spring draining a second golf course along with agricultural and forested areas, including a substantial contribution of subsurface water via karst connectivity. SWAt predictions of mean monthly tP loadings at the first two source outlets were deemed reasonable. However, the predictions at the cave spring outlet were somewhat poorer, likely due to diffuse variable groundwater flow from an unknown drainage area larger than the actual surface watershed, for which monthly subsurface flow was represented as a point source during simulations. Further testing of the SWAt model to predict monthly tP loadings at the R-E, modeled as a completely mixed system, resulted in their over-predictions most of the months, except when high lake water levels occurred. the mean monthly and annual flows were calibrated to acceptable limits with the exception of flow over-prediction when lake levels were low and surface water from tributaries disappeared into karst connections. the discrepancy in tP load predictions was attributed primarily to the use of limited monthly tP data collected during baseflow in the embayment. However, for the 22-month period, over-prediction of mean monthly tP load (34.6 kg/mo) by 13% compared to measured load (30.6 kg/mo) in the embayment was deemed acceptable. Simulated results showed a 42% reduction in tP load due to settling in the embayment.

关键词： Water Quality Models Lake Marion Runoff Groundwater (Baseflow) Losing Streams Deep Percolation Settling Rate

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

奇幻山谷

2017年

作者： (美)谭恩美(amy tan)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Puppy Love

Beijing Review 2008年第19期51卷 48-48页

作者： amy BAINBRIDGE

An unusual love affair has taken hold of me since I’ve been here in *** just seven weeks living here,I’m feeling a little obsessive. the love affair has nothing to do with my usual *** culinary delights of Beijing are spectacular,but something else has captured my senses. Dogs.I don’t want to eat them;it’s just that the gorgeous creatures are swamping me at every turn.I’ve watched in wonder at the splendid,manicured pooches that seem

关键词：中卫

Generation and characterization a conditional mouse model of Parkinson’s disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Generation and characterization a conditional mouse model of...