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Stroke Epidemiological Study at the Centre Hospitalier Universitaire (CHU) de Cocody in Abidjan, Côte D’Ivoire

Journal of Biosciences and Medicines 2023年第12期11卷 287-303页

作者： Abdoulaye Bâ Tiémélé Eugène Atayi amonchyépo ablan berth assi UFR Biosciences Université Félix Houphou&eumlt-Boigny Abidjan C&ocircte d’Ivoire UFR Sciences Médicales Université Félix Houphou&eumlt-Boigny Abidjan C&ocircte d’Ivoire

Background: Recent literature reported a recurrent increase in hemorrhagic stroke (HS) rates in low- and middle-income countries. However, the causes and mechanisms of the rising HS rates are unknown. To address these issues, the present epidemiological study was carried out in the neurovascular unit of the neurology department at the Centre Hospitalier Universitaire (CHU) de Cocody in Abidjan (Africa). Methods: The study included 60 patients hospitalized from January 1 to December 31, 2016, who underwent brain CT (computerized tomography) scans. We examined the medical records and survey forms in these patients with acute stroke (within 7 days) admitted to the Neurovascular Unit receiving only stroke patients. In these patients, we explored stroke distribution according to socio-demographic variables: age, gender and socio-professional categories. In addition, common risk factors were assessed. Results: In Côte d’Ivoire, our studies showed an ischemic stroke (IS) rate of 66.67% and a hemorrhagic stroke (HS) rate of 33.33%. Our studies indicated that stroke particularly affects the 40 - 60 age group. Then, stroke frequency has fallen in the 30 - 40 and 60 - 70 age groups, becoming rare in relatively young (70 years) subjects. In the sample analyzed, stroke occurred in women (56.67%) compared with men (43.33%). However, there was no gender-specific predilection for stroke. In addition, 90% of strokes occur in the working population and 10% in the non-working population. Arterial hypertension was the highest medical risk factor among patients (66.13%), compared with the other risk factors i.e. alcohol (17.42%), smoking (12.90%), previous stroke (9.67%), diabetes (6.65%), heart disease (6.65%) and dyslipidemia (3.23%). Specifically, hypertension was the main risk factor causing HS (45%) and IS (21.66%) in patients. Conclusion: Stroke particularly affected socio-economically active subjects (aged 40 - 60) in Africa, which were subjected to high prevalence of hemorrhagic

关键词： Hemorrhagic Stroke Ischemic Stroke Age Gender Hypertension Alcohol African Studies

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Comprehensive review into the challenges of gastrointestinal tumors in the Gulf and Levant countries

引用

World Journal of Clinical Cases 2020年第3期8卷 487-503页

作者： Rare Tumors GI Group Fadi Farhat Abdulaziz Al Farsi Ahmed Mohieldin Bassim Al Bahrani Eman Sbaity Hassan Jaffar Joseph Kattan Kakil Rasul Khairallah Saad Tarek assi Waleed El Morsi Rafid A Abood 不详 Hammoud Hospital UMC Saida PO Box 652Lebanon Medical Oncology Department Royal HospitalMuscat PO Box 1331Oman Medical Oncology Department Kuwait Cancer Control CenterKuwait PO Box 42262Kuwait Division of General Surgery American University of BeirutBeirut 11072180Lebanon Oncology Department Tawam HospitalAl Ain PO Box 15258United Arab Emirates Hemato-oncology Department Hotel Dieu de FranceBeirutLebanon Hemato-oncology Department National Center for Cancer Care and ResearchDohaQatar Pathology Department Institute National de PathologicBeirutLebanon Oncology Department Faculty of MedicineSaint-Joseph UniversityBeirutLebanon Pfizer Oncology-Emerging Markets Dubai Media CityDubaiUnited Arab Emirates Oncology Department Basra College of MedicineBasraIraq

Although gastrointestinal stromal tumors(GISTs)are rare,with an incidence of 1/100000 per year,they are the most common sarcomas in the peritoneal *** considerable progress in the diagnosis and treatment of GIST,about half of all patients are estimated to experience *** only two drugs,sunitinib and regorafenib,approved by the Food and Drug Administration,selecting treatment options after imatinib failure and coordinating multidisciplinary care remain *** addition,physicians across the Middle East face some additional and unique challenges such as lack of published local data from clinical trials,national disease registries and regional scientific research,limited access to treatment,lack of standardization of care,and limited access to mutational *** global guidelines set a framework for the management of GIST,there are no standard local guidelines to guide clinical practice in a resource-limited ***,a group of 11 experienced medical oncologists from across the Gulf and Levant region,part of the Rare Tumors Gastrointestinal Group,met over a period of one year to conduct a narrative review of the management of GIST and to describe regional challenges and gaps in patient management as an essential step to proposing local clinical practice recommendations.

关键词： Gastrointestinal stromal tumors Diagnosis Disease management Treatment Challenges Middle East

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