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Treatment-Plan Comparison of Three Advanced Radiation Treatment Modalities for Fractionated Stereotactic Radiotherapy to the Head and Neck

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International j.urnal of Medical Physics, Clinical Engineering and Radiation Oncology 2019年第2期8卷 106-120页

作者： He Wang j.mes N. Yang Xiaodong Zhang j.ng Li Steven j. Frank Zhongxiang Zhao Dershan Luo Xiaorong Zhu Congj.n Wang Samuel Tung Adam S. Garden David I. Rosenthal Clifton David Fuller Gary Brandon Gunn amol j. ghia j.y P. Reddy Shaan M. Raza Franco De Monte Mark S. Chambers Paul D. Brown Shirley Su j.ck Phan Department of Radiation Physics The University of Texas MD Anderson Cancer Center Houston TX USA Department of Radiation Oncology The University of Texas MD Anderson Cancer Center Houston TX USA Department of Neurosurgery The University of Texas MD Anderson Cancer Center Houston TX USA Department of Oncologic Dentistry Prosthodontics Thoracic/Head &Neck Surgery The University of Texas MD Anderson Cancer Center Houston TX USA Department of Radiation Oncology The Mayo Clinic Rochester MN USA

Purpose: Fractionated stereotactic radiosurgery (FSRS) can be given with at least three modalities: Gamma Knife, with the noninvasive frameless extend system (GKE);linear accelerator-based volumetric modulated arc therapy (VMAT);and intensity-modulated proton therapy (IMPT). We extracted treatment plans for patients who had received FSRS with GKE for recurrent skull base or intracranial tumors, created corresponding plans for VMAT and IMPT, and compared the quality of the three sets of plans. Methods and materials: Plans were extracted for 9 patients with recurrent malignant skull-base tumors (n = 6) or large intracranial tumors (n = 3) who had received FSRS with GKE (median dose 24 Gy in 3 fractions) in 2013 through 2015. Plans for VMAT were generated with a TrueBeam STx LINAC machine using 6-MV photons, and plans for IMPT were generated with multi-field optimization. The optimized VMAT and IMPT plans were normalized to achieve the best possible target coverage while meeting the same dose-volume constraints on organs at risk (OARs) as the GKE plans. Plans were evaluated on the basis of target coverage, conformity index, homogeneity index, gradient index, and treatment efficiency. Results: The median target volume was 10.2 cm3 (range 1.9 - 33.8 cm3). The VMAT and IMPT plans met all OAR constraints, and target coverage and conformity were comparable among all plans. VMAT and IMPT plans showed significantly better target uniformity and treatment delivery efficiency (P P Conclusion: FSRS for skull base and large intracranial lesions delivered by VMAT and IMPT can achieve comparable target coverage, conformity, and sparing of critical structure as the GKE while providing superior target uniformity and treatment delivery efficiency. The GKE had superior high-dose gradients outside the target and thus better protected surrounding normal structures.

关键词： Gamma Knife Extend System Stereotactic Radiosurgery Volumetric Modulated Arc Therapy Intensity-Modulated Proton Therapy Spot Scanning Proton Therapy

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Knowledge‐based deep learning system for classifying Alzheimer's disease for multi‐task learning

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CAAI Transactions on Intelligence Technology 2024年第4期9卷 805-820页

作者： amol Dattatray Dhaygude Gaurav Kumar Ameta Ihtiram Raza Khan Pavitar Parkash Singh Renato RMaaliw III Natrayan Lakshmaiya Mohammad Shabaz Muhammad Attique Khan Hany SHussein Hammam Alshazly Department of Data Science University of WashingtonSeattleWashingtonUSA Department of Computer Science&Engineering Parul Institute of TechnologyParul UniversityVadodaraGujaratIndia Department of Computer Science Jamia HamdardDelhiIndia Department of Management Lovely Professional UniversityPhagwaraIndia 5 College of Engineering Southern Luzon State UniversityLucbanQuezonPhilippines Department of Mechanical Engineering Saveetha School of EngineeringSIMATSChennaiTamil NaduIndia Model Institute of Engineering and Technology JammuJ&KIndia Department of Computer Science HITEC UniversityTaxilaPakistan Department of Computer Science and Mathematics Lebanese American UniversityBeirutLebanon Electrical Engineering Department College of EngineeringKing Khalid UniversityAbhaSaudi Arabia Electrical Engineering Department Aswan UniversityAswanEgypt Faculty of Computers and Information South Valley UniversityQenaEgypt

Deep learning has recently become a viable approach for classifying Alzheimer's disease(AD)in medical ***,existing models struggle to efficiently extract features from medical images and may squander additional information resources for illness *** address these issues,a deep three‐dimensional convolutional neural network incorporating multi‐task learning and attention mechanisms is *** upgraded primary C3D network is utilised to create rougher low‐level feature *** introduces a new convolution block that focuses on the structural aspects of the magnetic resonance imaging image and another block that extracts attention weights unique to certain pixel positions in the feature map and multiplies them with the feature map ***,several fully connected layers are used to achieve multi‐task learning,generating three outputs,including the primary classification *** other two outputs employ backpropagation during training to improve the primary classification *** findings show that the authors’proposed method outperforms current approaches for classifying AD,achieving enhanced classification accuracy and other in-dicators on the Alzheimer's disease Neuroimaging Initiative *** authors demonstrate promise for future disease classification studies.

关键词： classification deep learning

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聚酯/棉导电织物在产业用纺织品开发中的创新应用

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国际纺织导报 2012年第9期40卷 47-48,50页

作者： amol j.Patil Smita C.Deogaonkar 张慧孟买纺织研究协会(印度)

在聚酯/棉混纺织物上通过2步法成功实施了聚吡咯的原位聚合,所得样品单位面积的表面电阻率在50～2500Ω。该电导率范围适用于很多产业用纺织品领域。扫描电镜显示,聚合物完全覆盖了纤维和纱线间的空隙。耐久性研究发现,水洗会导致电导... 详细信息

在聚酯/棉混纺织物上通过2步法成功实施了聚吡咯的原位聚合,所得样品单位面积的表面电阻率在50～2500Ω。该电导率范围适用于很多产业用纺织品领域。扫描电镜显示,聚合物完全覆盖了纤维和纱线间的空隙。耐久性研究发现,水洗会导致电导率的显著损失。而干洗影响相对较小,电导率损失可相对忽略不计。为了扩展其应用领域,进一步的研究需着重于改善聚吡咯涂层纺织品的耐水洗性。

关键词：聚酯/棉混纺织物吡咯聚合表面电阻率耐久性

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Rotating Charged Hairy Black Hole in(2+1) Dimensions and Particle Acceleration

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Communications in Theoretical Physics 2014年第9期61卷 358-362页

作者： j.Sadeghi B.Pourhassan H.Farahani Department of Physics Islamic Azad University-Ayatollah Amoli Branch P.O. Box 678 Amol Iran Young Researchers Club Ayatollah Amoli Branch Islamic Azad University Amol Iran Department of Physics Damghan University Damghan Iran

In this paper, we construct rotating charged hairy black hole in(2+1) dimensions for infinitesimal black hole charge and rotation parameters. Then we consider this black hole as particle accelerator and calculate the centerof-mass energy of two colliding test particles near the rotating charged hairy black hole in(2+1) dimensions. As we expected, the center-of-mass energy has infinite value.

关键词： particle acceleration 3D black hole thermodynamics

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在完全隔离的小群体中伴性基因頻率的随机漂移过程

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Acta Biochimica et Biophysica Sinica 1966年第2期 130-142页

作者：楊紀珂張少吾丁蓉原李家瑤中国科学院生物物理研究所中国科学技术大学应用数学系中国科学技术大学生物物理系中国科学技术大学生物物理系北京 1964年毕业生

(1) 以在世系間完全隔离,且在没有选擇、突变、与迁移的理想情况为依据,探討了伴性基因頻率随世代而变化的随机漂移过程。确认其为Markov鏈。（2）立出了这个鏈的轉移概率矩陣。由于0,0与Z2n,n是两个吸收态,使矩陣左上与右下两角的概... 详细信息

(1) 以在世系間完全隔离,且在没有选擇、突变、与迁移的理想情况为依据,探討了伴性基因頻率随世代而变化的随机漂移过程。确认其为Markov鏈。（2）立出了这个鏈的轉移概率矩陣。由于0,0与Z2n,n是两个吸收态,使矩陣左上与右下两角的概率为一。（3）解出了最終固定于以上两吸收态的概率,它們取决于初始世代的两性基因頻数,固定于状态Z2n,n的概率为（i0+j.）/3n,固定于Z0,0的为1—（i0+j.）/3n。（4）推导出了各世代两性基因頻率的二維概率密度以及边緣概率密度之間的递推关系。（5）从矩母函数推导出各世代两性伴性基因頻率的平均数間的递推关系,与确定性模型的結果完全相一致。（6）推导出了在各世代中世系間雌雄群体的方差与协方差,以及在世系內雌雄群体的方差老甸g方差随世代t而增,逐漸达于一个极限;世系內方差則在t1以后随世代t而减,逐漸达于零。这与生物遺傳的实际規律相符:在小群体間因隔离而引起的分散性随世代而增,而在小群体內的相象性（純合体的增加）則随世系而减。（7）从以上模型推得的理論結果,作了一些数字的計算,获得了驗証。（8）进行了一个以果蝇为材料的实驗,在所得实驗結果与理論結果之間存在着良好的吻合性。

关键词：伴性基因世代雌雄概率密度加权平均数数学期望吸收态随机漂移

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