检索结果-南通市图书馆

Chinese Journal of Chemical Engineering 2014年第3期22卷 274-286页

作者： Delara Mohammad-Aghaie Mohammad Mehdi Papari amjad reza ebrahimi Department of Chemistry Shiraz University of Technology

The present work is concerned with extracting information about intermolecular potential energies of binary mixtures of CO2 with C2H6, C3H8, n-C4Hlo and iso-C4Hlo, by the usage of the inversion method, and then predicting the dilute gas transport properties of the mixtures. Using the inverted pair potential energies, the Chap- man-Enskog version of the kinetic theory was applied to calculate transport properties, except thermal conductivity of mixtures. The calculation of thermal conductivity through the methods of Schreiber et al. and Uribe et al. was discussed. Calculations were performed over a wide temperature range and equimolar composition. Rather accurate correlations for the viscosity coefficients of the mixtures in the temperature range were reproduced from the pre- sent unlike intermolecular potential energies. Our estimated accuracies for the viscosity are within ±2%. Acceptable agreement between the predicted values of the viscosity and thermal conductivity with the literature values demon- strates the predictive power of the inversion scheme. In the case of thermal conductivity our results are in favor of the preference of Uribe et al.＇s method over Schreiber et al.＇s scheme.

关键词： intermolecular potential transport properties carbon dioxide inversion scheme

Nonlinear phenomena in vibrations of embedded carbon nanotubes conveying viscous fluid

在线全文

学校读者我要写书评

暂无评论

Nanotechnology and Precision Engineering 2024年第1期7卷 44-54页

作者： reza ebrahimi Mechanical Engineering Faculty of EngineeringYasouj UniversityYasouj 75918-74831Iran

Various nonlinear phenomena such as bifurcations and chaos in the responses of carbon nanotubes(CNTs)are recognized as being major contributors to the inaccuracy and instability of nanoscale mechanical ***,the main purpose of this paper is to predict the nonlinear dynamic behavior of a CNT conveying viscousﬂuid and supported on a nonlinear elastic *** proposed model is based on nonlocal Euler–Bernoulli beam *** Galerkin method and perturbation analysis are used to discretize the partial differential equation of motion and obtain the frequency-response equation,respectively.A detailed parametric study is reported into how the nonlocal parameter,foundation coefﬁcients,ﬂuid viscosity,and amplitude and frequency of the external force inﬂuence the nonlinear dynamics of the ***,quasi-periodic,and chaotic behaviors and hardening nonlinearity are revealed by means of the vibration time histories,frequency-response curves,bifurcation diagrams,phase portraits,power spectra,and Poincaré***,the results show that it is possible to eliminate irregular motion in the whole range of external force amplitude by selecting appropriate parameters.

关键词： Nonlinear vibration Carbon nanotubes Nonlocal effect Viscousﬂuid Nonlinear elastic medium

Immunologic tumor microenvironment modulators for turning cold tumors hot

在线全文

学校读者我要写书评

暂无评论

Cancer Communications 2024年第5期44卷 521-553页

作者： Gholam-reza Khosravi Samaneh Mostafavi Sanaz Bastan Narges ebrahimi Roya Safari Gharibvand Nahid Eskandari Department of Medical Immunology School of MedicineIsfahan University of Medical SciencesIsfahanIran Department of Immunology Faculty of Medical SciencesTarbiat Modares UniversityTehranIran Department of Immunology School of MedicineAhvaz Jundishapur University of Medical SciencesAhvazIran

Tumors can be classified into distinct immunophenotypes based on the presence and arrangement of cytotoxic immune cells within the tumor microenvironment(TME).Hot tumors,characterized by heightened immune activity and responsiveness to immune checkpoint inhibitors(ICIs),stand in stark contrast to cold tumors,which lack immune infiltration and remain resistant to *** overcome immune evasion mechanisms employed by tumor cells,novel immunologic modulators have emerged,particularly ICIs targeting cytotoxic T-lymphocyte-associated protein 4(CTLA-4)and programmed cell death protein 1/programmed death-ligand 1(PD-1/PD-L1).These agents disrupt inhibitory signals and reactivate the immune system,transforming cold tumors into hot ones and promoting effective antitumor ***,challenges persist,including primary resistance to immunotherapy,autoimmune side effects,and tumor response *** these challenges requires innovative strategies,deeper mechanistic insights,and a combination of immune interventions to enhance the effectiveness of *** the landscape of cancer medicine,where immune cold tumors represent a formidable hurdle,understanding the TME and harnessing its potential to reprogram the immune response is *** review sheds light on current advancements and future directions in the quest for more effective and safer cancer treatment strategies,offering hope for patients with immune-resistant tumors.

关键词： cold tumor hot tumor immunologic modulator immunotherapy therapeutic strategy tumor microenvironment

Outcomes of surgical correction of Peyronie’s disease with plaque excision and grafting: Comparison of testicular tunica vaginalis graft versus bovine pericardium graft

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Urology 2024年第3期11卷 497-503页

作者： Ali Eslahi Faisal Ahmed Mohammad reza Askarpour Hossein-Ali Nikbakht Iman Shamohammadi Payam Ghasemi Hanieh Alimardani Bahareh ebrahimi Department of Urology School of MedicineShiraz University of Medical SciencesShirazIran Shiraz Geriatric Research Center Shiraz University of Medical SciencesShirazIran Urology Research Center Al-Thora General HospitalDepartment of UrologySchool of MedicineIbb University of Medical SciencesIbbYemen Social Determinants of Health Research Center Health Research InstituteBabol University of Medical SciencesBabolIran

Objective:Peyronie’s disease(PD)is an abnormal wound healing in the penile tunica *** fibrotic plaque excision,different graft materials have been used to repair the defects,but the optimal graft remains *** study aimed to compare the functional outcomes of testicular tunica vaginalis grafts and bovine pericardium grafts in patients with severe ***:A retrospective comparative study was conducted on 33 PD patients undergoing partial plaque excision and grafting from September 2015 to May *** patients were divided into two groups depending on the type of graft *** 15 patients in Group B,testicular tunica vaginalis grafts were used to repair the defect,while for 18 patients in Group A,bovine pericardium grafts were *** of the patient’s age,comorbidities,sexual function,penile curvature,postoperative complications,need for further treatment,change in penile length,and satisfaction were gathered and compared between the *** function was evaluated using the 5-item version of the International Index of Erectile Function(IIEF-5),and a functional less than 20-degree penile curvature after surgery was considered a successful ***:There was no difference in age,comorbidities,degree of curvature,perioperative IIEF-5,operative time,plaque size,or complication *** surgery,a statistically significant improvement in curvature degree(p<0.05)and satisfactory penile appearance(p<0.05)were seen in both groups without any superiority between the two groups(p=0.423 and p=0.840,respectively).With a 30-month follow-up,the IIEF-5 was consistent in both groups,with no statistical significance between the groups(p=0.492).The main change in penile length during the operation was increased and still positive in the last follow-up in both groups without statistical significance(p=0.255 and p=0.101,respectively).Conclusion:Partial plaque excision and corporoplasty with both testicular tunica vaginalis or bovine pericard

关键词： Peyronie's disease Plaqueexcision Testiculartunica vaginalis graft Bovinepericardium graft

Analysis of cohesive particles mixing behavior in a twin-paddle blender:DEM and machine learning applications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2024年第7期90卷 350-363页

作者： Behrooz Jadidi Mohammadreza ebrahimi Farhad Ein-Mozaffari Ali Lohi Department of Chemical Engineering Toronto Metropolitan University350 Victoria StreetToronto M5B 2K3Canada

This research paper presents a comprehensive discrete element method(DEM)examination of the mixing behaviors exhibited by cohesive particles within a twin-paddle blender.A comparative analysis between the simulation and experimental results revealed a relative error of 3.47%,demonstrating a strong agreement between the results from the experimental tests and the DEM *** main focus centers on systematically exploring how operational parameters,such as impeller rotational speed,blender's fill level,and particle mass ratio,influence the *** investigation also illustrates the significant influence of the mixing time on the mixing *** gain a deeper understanding of the DEM simulation findings,an analytical tool called multivariate polynomial regression in machine learning is *** method uncovers significant connections between the DEM results and the operational parameters,providing a more comprehensive insight into their *** multivariate polynomial regression model exhibited robust predictive performance,with a mean absolute percentage error of less than 3%for both the training and validation sets,indicating a slight deviation from actual *** model's precision was confirmed by low mean absolute error values of 0.0144(80%of the dataset in the training set)and 0.0183(20%of the dataset in the validation set).The study offers valuable insights into granular mixing behaviors,with implications for enhancing the efficiency and predictability of the mixing processes in various industrial applications.

关键词： Machine learning Granular mixing Discrete element method Mixing kinetics and mechanism Cohesive particles

A review of the literature on the use of CRISPR/Cas9 gene therapy to treat hepatocellular carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第3期32卷 439-461页

作者： ELHAM amjad RAFAELE PEZZANI BABAK SOKOUTI Biotechnology Research Center Tabriz University of Medical SciencesTabriz***Iran Phytotherapy Lab Endocrinology UnitDipartimento di Medicina(DIMED)University of PadovaVia Ospedale 105Padova35128Italy Associazione Italiana Per La Ricerca Oncologica Di Base Associazione Italiana Per La Ricerca Oncologica Di BasePadova35128Italy

Noncoding RNAs instruct the Cas9 nuclease to site speifillyl cleave DNA in the CRISPR/Cas9 *** the high incidence of hepatocellular carcinoma(HCC),the patient's outcome is *** a result of the emergence of therapeutic resistance in HCC patients,dlinicians have faced difficulties in treating such *** addition,CRISPR/Cas9 screens were used to identify genes that improve the dlinical response of HCC *** is the objective of this article to summarize the current understanding of the use of the CRISPR/Cas9 system for the treatment of cancer,with a particular emphasis on HCC as part of the current state of ***,in order to locate recent developments in oncology research,we examined both the Scopus database and the PubMed *** ability to selectively interfere with gene expression in combinatorial CRISPR/Cas9 screening can lead to the discovery of new effective HCC treatment regimens by combining clinically approved *** resistance can be overcome with the help of the CRISPR/Cas9 *** signature genes and resistance to treatment have been uncovered by genome-scale CRISPR activation screening although this method is not without *** has been extensively examined whether CRISPR can be used as a tool for disease research and gene *** and its applications to tumor research,particularly in HCC,are examined in this study through a review of the literature.

关键词： CRISPR/Cas9 system Gene therapy Tumor Hepatocellular carcinoma Liver cancer Gene editing

Smart prediction of liquefaction-induced lateral spreading

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2310-2325页

作者： Muhammad Nouman amjad Raja Tarek Abdoun Waleed El-Sekelly New York University(NYU)Abu Dhabi Abu Dhabi129188United Arab Emirates University of Management and Technology Lahore54372Pakistan Department of Civil and Environmental Eng. Rensselaer Polytechnic Institute(RPI)1108th StreetJEC 4049TroyNY12180USA Department of Structural Engineering Mansoura UniversityMansoura35516Egypt

The prediction of liquefaction-induced lateral spreading/displacement(Dh)is a challenging task for civil/geotechnical *** this study,a new approach is proposed to predict Dh using gene expression programming(GEP).Based on statistical reasoning,individual models were developed for two topographies:free-face and gently sloping *** with a comparison with conventional approaches for predicting the Dh,four additional regression-based soft computing models,*** process regression(GPR),relevance vector machine(RVM),sequential minimal optimization regression(SMOR),and M5-tree,were developed and compared with the GEP *** results indicate that the GEP models predict Dh with less bias,as evidenced by the root mean square error(RMSE)and mean absolute error(MAE)for training(i.e.1.092 and 0.815;and 0.643 and 0.526)and for testing(i.e.0.89 and 0.705;and 0.773 and 0.573)in free-face and gently sloping ground topographies,*** overall performance for the free-face topology was ranked as follows:GEP>RVM>M5-tree>GPR>SMOR,with a total score of 40,32,24,15,and 10,*** the gently sloping condition,the performance was ranked as follows:GEP>RVM>GPR>M5-tree>SMOR with a total score of 40,32,21,19,and 8,***,the results of the sensitivity analysis showed that for both free-face and gently sloping ground,the liquefiable layer thickness(T_(15))was the major parameter with percentage deterioration(%D)value of 99.15 and 90.72,respectively.

关键词： Lateral spreading Intelligent modeling Gene expression programming(GEP) Closed-form solution Feature importance

Microstructure and impact behavior of Mg-4Al-5RE-xGd cast magnesium alloys

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2024年第5期12卷 1799-1814页

作者： Jie Wei Qudong Wang Huisheng Cai Mahmoud ebrahimi Chuan Lei National Engineering Research Center of Light Alloy Net Forming and Key State Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China

This work investigated the microstructure and impact behavior of Mg-4Al-5RE-xGd(RE represents La-Ce mischmetal;x=0,0.2,0.7 wt.%)alloys cast by high-pressure die casting(HPDC),permanent mold casting(PMC),and sand casting(SC)*** results indicated that with increasing Gd content,the grain sizes of the HPDC alloy had a slight change,but the grains of the PMC and SC alloys were significantly ***,the acicular Al_(11)RE_(3)phase was modified into the short-rod shape under the three casting *** impact toughness of the studied alloy was mainly dominated by the absorbed energy during the crack *** increasing Gd content,the impact toughness of the studied alloy monotonically increased due to the lower tendency of the modified second phase toward crack *** impact stress was higher than the tensile stress,exhibiting a strain rate sensitivity for the mechanical response;however,the HPDC alloy had an inconsistent strain rate sensitivity during the impact event due to the transformation of the deformation mechanism from twinning to slip with increasing *** dimples covered the fracture surface of the fine-grained HPDC alloys,indicating a typical ductile ***,due to the deficient{1012}twinning activity and the suppressed grain boundary sliding during the impact event,the HPDC alloys showed insufficient plastic deformation capacity.

关键词： Mg-Al-RE alloy Gadolinium Microstructure Impact behavior

Temperature-jump tensile tests to induce optimized TRIP/TWIP effect in a metastable austenitic stainless steel

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2025-2036页

作者： Mohammad Javad Sohrabi Hamed Mirzadeh Saeed Sadeghpour Abdol reza Geranmayeh reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland

In the present work,plastic deformation mechanisms were initially tailored by adjusting the deformation temperature in the range of 0 to 200℃ in AISI 304L austenitic stainless steel,aiming to optimize the strength-ductility *** was shown that the combined twinning-induced plasticity(TWIP)/transformation-induced plasticity(TRIP)effects and a wider strain range for the TRIP effect up to higher strains by adjusting the deformation temperature are good strategies to improve the strength-ductility synergy of this metastable stainless *** this regard,by consideration of the observed temperature-dependency of plastic deformation,the controlled sequence of TWIP and TRIP effects for archiving superior strength-ductility trade-off was intended by the pre-designed temperature jump tensile ***,the optimum tensile toughness of 846 MJ/m^(3) and total elongation to 133% were obtained by this strategy via exploiting the advantages of the TWIP effect at 100℃ and the TRIP effect at 25℃ at the later stages of the ***,a deformation-temperature-transformation(DTT)diagram was developed for this metastable ***,based on work-hardening analysis,it was found that the main phenomenon constraining further improvement in the ductility and strengthening was the yielding of the deformation-induced α′-martensite.

关键词： metastable stainless steels transformation-induced plasticity twinning-induced plasticity stacking fault energy mechanical properties

Particle size distribution in a multi-zone circulating fluidized bed polymerization reactor

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第10期93卷 291-299页

作者： Mohammadhossein Hadadiyan Navid Mostoufi reza Marandi Process Design and Simulation Research Centre School of Chemical EngineeringCollege of EngineeringUniversity of TehranP.O.Box 11155-4563TehranIran Polymer Research Group Petrochemical Research and Technology CompanyNational Petrochemical CompanyP.O.Box 14358/84711TehranIran

This research focuses on modeling a multi-zone circulating reactor(MZCR)in the polypropylene production *** these reactors,designed for polyolefin production,small catalyst particles(20–300μm)initiate polymerization in the presence of monomer *** reactor consists of two main regions:the riser and the *** riser operates in the fast fluidization and the downer is in the moving bed *** the two-fluid model with the Eulerian-Eulerian approach,the dynamics of both solid and gas phases were modeled by applying Newton's laws of motion and assuming spherical *** population balance of particles within the reactor was also coupled with the equations of *** simultaneous solution of these equations provides valuable insights into particle and fluid behavior,revealing trends such as the growth of polymer ***,the impact of various operating conditions was *** study also examined the effects of design parameters(gas inlet velocity,average inlet diameter,and temperature)on the system *** instance,it was shown that in the case where the solid circulation flux is 30 kg/(m^(2) s)the velocity of particles in the bed increases from 0.4 at the inlet to 1.1 m/s in the fully developed zone,when it is 43 kg/(m^(2) s)the velocity of particles increases from 0.3 to 1.4 m/s,and when it is 55 kg/(m^(2) s),it is increased from 0.22 to 1.5 m/***,trends in particle size distribution based on temperature adjustments were *** study showed that higher temperatures accelerate the polymerization reaction rate,promoting faster growth kinetics and the formation of larger particles.

关键词： Fluidization Polymerization Gas-solid flow Multi-zone circulating reactor(MZCR) CFD-PBM Two-fluidmodel