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Antimicrobial and synergistic effects of lemongrass and geranium essential oils against Streptococcus mutans,Staphylococcus aureus,and Candida spp.

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World Journal of Critical Care Medicine 2024年第3期13卷 63-74页

作者： Patrícia Michelle Nagai de Lima Thaís Cristine Pereira Lara Steffany de Carvalho Letícia Ferreira dos Santos Carlos Eduardo Rocha Oliveira Lucas de Paula Ramos Maria Cristina Marcucci amjad abu hasna Luciane Dias de Oliveira Department of Biosciences and Oral Diagnosis Institute of Science and TechnologySão Paulo State UniversitySão Josédos Campos 12245000SPBrazil Anhembi Morumbi University School of MedicineSão Josédos Campos 12230-002SPBrazil Department of Restorative Dentistry Endodontics DivisionInstitute of Science and TechnologySão Paulo State UniversitySão Josédos Campos 12245000São PauloBrazil

BACKGROUND The oral cavity harbors more than 700 species of bacteria,which play crucial roles in the development of various oral diseases including caries,endodontic infection,periodontal infection,and diverse oral *** To investigate the antimicrobial action of Cymbopogon Schoenanthus and Pelargonium graveolens essential oils against Streptococcus mutans,Staphylococcus aureus,Candida albicans,***,and *** Minimum microbicidal concentration was determined following Clinical and Laboratory Standards Institute *** synergistic antimicrobial activity was evaluated using the Broth microdilution checkerboard method,and the antibiofilm activity was evaluated with the 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide *** were analyzed by one-way analysis of variance followed by the Tukey post-hoc test(P≤0.05).RESULTS *** and *** essential oils were as effective as 0.12%chlorhexidine against *** and *** monotypic biofilms after 24 *** 24 h *** essential oil at 0.25%was more effective than the nystatin group,and *** essential oil at 0.25%was as effective as the nystatin *** *** and *** essential oils are effective against ***,***,***,***,and *** at different concentrations after 5 min and 24 h.

关键词： Antifungal effect Lemongrass Geranium Candida albicans Candida dubliniensis Candida krusei Staphylococcus aureus Streptococcus mutans

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Smart prediction of liquefaction-induced lateral spreading

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第6期16卷 2310-2325页

作者： Muhammad Nouman amjad Raja Tarek Abdoun Waleed El-Sekelly New York University(NYU)abu Dhabi Abu Dhabi129188United Arab Emirates University of Management and Technology Lahore54372Pakistan Department of Civil and Environmental Eng. Rensselaer Polytechnic Institute(RPI)1108th StreetJEC 4049TroyNY12180USA Department of Structural Engineering Mansoura UniversityMansoura35516Egypt

The prediction of liquefaction-induced lateral spreading/displacement(Dh)is a challenging task for civil/geotechnical *** this study,a new approach is proposed to predict Dh using gene expression programming(GEP).Based on statistical reasoning,individual models were developed for two topographies:free-face and gently sloping *** with a comparison with conventional approaches for predicting the Dh,four additional regression-based soft computing models,*** process regression(GPR),relevance vector machine(RVM),sequential minimal optimization regression(SMOR),and M5-tree,were developed and compared with the GEP *** results indicate that the GEP models predict Dh with less bias,as evidenced by the root mean square error(RMSE)and mean absolute error(MAE)for training(i.e.1.092 and 0.815;and 0.643 and 0.526)and for testing(i.e.0.89 and 0.705;and 0.773 and 0.573)in free-face and gently sloping ground topographies,*** overall performance for the free-face topology was ranked as follows:GEP>RVM>M5-tree>GPR>SMOR,with a total score of 40,32,24,15,and 10,*** the gently sloping condition,the performance was ranked as follows:GEP>RVM>GPR>M5-tree>SMOR with a total score of 40,32,21,19,and 8,***,the results of the sensitivity analysis showed that for both free-face and gently sloping ground,the liquefiable layer thickness(T_(15))was the major parameter with percentage deterioration(%D)value of 99.15 and 90.72,respectively.

关键词： Lateral spreading Intelligent modeling Gene expression programming(GEP) Closed-form solution Feature importance

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National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid Mohammad Salih Abdullah Saeed amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan Rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

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Effect of co-presence of NSAIDs with cadmium:i)evaluation of NSAIDbearing water for washing Cd from soil,ii)Cd removal from NSAIDbearing water using magnetic graphene oxide

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Emerging Contaminants 2022年第1期8卷 151-161页

作者： amjad H.El-Sheikh Haneen K.abu-Dgham Mahmoud S.Sunjuk Nabil N.Al-Hashimi Department of Chemistry Faculty of ScienceThe Hashemite UniversityP.O.Box 330127Zarqa13133Jordan Faculty of Pharmacy The Hashemite UniversityP.O.Box 330127Zarqa13133Jordan

Cadmium“Cd”is a toxic pollutant that may present in soil and *** work evaluates:i)the use of non-steroidal anti-inflammatory drugs“NSAIDs”-bearing water for washing soil containing Cd(Ⅱ),ii)removal of Cd(Ⅱ)from NSAID-bearing water by adsorption onto magnetic graphene oxide which can be easily separated by strong *** studied NSAIDs are aspirin,ketoprofen,ibuprofern and *** Cd(Ⅱ)-NSAIDs complexes were synthesized and characterized by *** was initially oxidized by either nitric acid,or ammonium persulphate method,or Hummer's *** was then deposited on graphene oxide to give the corresponding magnetic graphene oxides(NA-MGO,APSMGO and Hum-MGO,respectively).The effect of the following factors on Cd(Ⅱ)uptake was investigated:NSAIDs type,pH,graphene oxidation method,magnetite:graphene oxide mass ratio in the adsorbent,(Cd(Ⅱ):NSAID)molar *** Cd(Ⅱ)uptake was achieved using“magnetic graphene oxidized with ammonium persulphate where the mass ratio of magnetite to graphene oxide was 2:1”in the presence of diclofenac at *** best Cd(Ⅱ):diclofenac molar ratio was 1:*** maximum adsorption capacity of Cd(Ⅱ)was found to be 83 mg L*** regeneration of the adsorbent was possible by 0.3 M HNO3 solution and 80%of adsorption efficiency was maintained after five *** presence of coexisting ions,80%of the adsorption efficiency was *** NSAIDs-containing waters were used for washing Cd-containing soil;the maximum removal efficiencies of Cd were 18%and 16%using 5 mM diclofenac or 10 mM aspirin,*** diclofenac or aspirin-spiked real pharmaceutical wastewater gave 28%removal of *** optimum adsorption method was used for removal of Cd(Ⅱ)from diclofenac-containing soil-washing water,where two successive adsorptions were needed for complete Cd uptake.

关键词： Adsorption Cadmium Magnetic graphene oxide NSAIDs Pharmaceutical wastewater Soil washing

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