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Herbal antioxidant in clinical practice:A review

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Asian Pacific Journal of Tropical Biomedicine 2014年第1期4卷 78-84页

作者： Shashi Alok Sanjay Kumar Jain amita verma Mayank Kumar Alok Mahor Monika Sabharwal Institute Of Pharmacy Bundelkhand University Department of Pharmaceutical Sciences Faculty of Health SciencesSam Higginbottom Institute of AgricultureTechnology and Sciences-DeemedUniversity Society of Pharmaceutical Sciences and Research

Antioxidant-the word itself is *** the antioxidant concept as a spearhead in proposed mechanisms for staving off so-called"free-radical"reactions,the rush is on to mine claims for the latest and most effective combination of free-radical scavenging *** must acknowledge that such"radicals"have definitively been shown to damage all biochemical components such as DNA/HNA,carbohydrates,unsaturated lipids,proteins,and micronutrients such as carotenoids(alpha and beta carotene,lycopene),vitamins A,B_6,B_(12),and *** strategies against such aggressive radical species include enzymes,antioxidants that occur naturally in the body(glutathione,uric acid,ubiquinol-10,and others)and radical scavenging nutrients,such as vitamins A,C,and E,and *** paper will present a brief discussion of some well-and little-known herbs that may add to the optimization of antioxidant status and therefore offer added preventive values for overall *** is important to state at the outset that antioxidants vary widely in their free-radical quenching effects and each may be individually attracted to specific cell *** evidence of the specialized nature of the carotenoids is demonstrated by the appearance of two carotenoids in the macula region of the retina where beta-carotene is totally

关键词： Antioxidant Carotenoid Free-radical Herb

Morphology,pharmacological activity,pharmaceutical preparation,doses and side effect of Coccinia indica(Wight&Arn.):An overview

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Journal of Coastal Life Medicine 2013年第4期 330-336页

作者： Mayank Kumar Shashi Alok Sanjay Kumar Jain amita verma Alok Mahor Monika Sabharwal Institute of Pharmacy Bundelkhand UniversityJhansi(U.P.)India Department of Pharmacy Sam Higginbottom Institute of AgricultureTechnology and SciencesAllahabad(U.P.)India Society of Pharmaceutical Sciences and Research Panchkula(Haryana)India

Traditional system of medicine consists of large number of plants with various medicinal and pharmacological importances and hence represents a priceless tank of new bioactive *** indica belongs to the family *** is a rapidly growing,perennial climber or trailing *** different parts of this plant namely the roots,leaves and fruits are used in folklore medicine for several purposes like jaundice,diabetes,wound healing,ulcers,stomach ache,skin disease,fever,asthma,*** leaf and its constituents have been reported to possess hypoglycaemic,hypolipidemic and antioxidant *** review provides adequate information to develop suitable therapeutics out of these plant parts.

关键词： Coccinia indica(Ivy Gourd) Antidiabetic activity Antibacterial activity

Antihepatotoxic Effect of Feronia Limonia Fruit against Carbon Tetrachloride Induced Hepatic Damage in Albino Rats

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Chinese Medicine 2010年第1期1卷 18-22页

作者： Rucha Upadhyay Narendra Deo Pandey Shahid Suhail Narvi amita verma Bahar Ahmed Department of Chemistry Motilal Nehru National Institute of Technology Department of Pharmaceutical Chemistry Faculty of Pharmacy Hamdard University

Feronia limonia Swingle, though mentioned as a high utility medicinal plant in Ayurveda for the treat-ment of liver disorders, but has no scientific investigations. Therefore, the present study was undertaken to investigate the hepatoprotective activity of extracts of Feronia limonia fruit on albino rat liver, damage induced by single dose of carbon-tetrachloride (1.5 ml/kg, p.o.). The oral administration of extracts (500 mg/kg, p.o.) for 7 days has shown significant hepatoprotective action. There is reduction in the elevated levels of serum enzymes such SGOT, SGPT, ALP and Serum bilirubin and elevation in level of GSH, GPX,GLY and total protein in Feronia limonia protected rats.

关键词： Anti-Hepatotoxic Carbon Tetrachloride Feronia Limonia Swingle

Role of photon-counting computed tomography in pediatric cardiovascular imaging

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World Journal of Clinical Pediatrics 2025年第1期14卷 55-62页

作者： Arosh S Perera Molligoda Arachchige Yash verma Faculty of Medicine Humanitas UniversityPieve Emanuele 20072Italy Department of Radiology Mayo ClinicRochesterMN 55905United States

Photon-counting computed tomography(PCCT)represents a significant advancement in pediatric cardiovascular *** CT systems employ energy-integrating detectors that convert X-ray photons into visible light,whereas PCCT utilizes photon-counting detectors that directly transform X-ray photons into electric *** direct conversion allows photon-counting detectors to sort photons into discrete energy levels,thereby enhancing image quality through superior noise reduction,improved spatial and contrast resolution,and reduced *** pediatric applications,PCCT offers substantial benefits,including lower radiation doses,which may help reduce the risk of malignancy in pediatric patients,with perhaps greater potential to benefit those with repeated exposure from a young *** spatial resolution facilitates better visualization of small structures,vital for diagnosing congenital heart ***,PCCT’s spectral capabilities improve tissue characterization and enable the creation of virtual monoenergetic images,which enhance soft-tissue contrast and potentially reduce contrast media *** clinical results indicate that PCCT provides superior image quality and diagnostic accuracy compared to conven-tional CT,particularly in challenging pediatric cardiovascular *** PCCT technology matures,further research and standardized protocols will be essential to fully integrate it into pediatric imaging practices,ensuring optimized diagnostic outcomes and patient safety.

关键词： Cardiovascular Photon-counting detectors Pediatric Photon-counting computed tomography Computed tomography

Comparison of Dartos flap and spongioplasty in Snodgrass urethroplasty in distal penile hypospadias

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World Journal of Pediatric Surgery 2021年第3期4卷 39-43页

作者： Anju verma Shahid Murtaza Vijay Kumar Kundal amita Sen Divya Gali Department of Paediatric Surgery Dr Ram Manohar Lohia Hospital and Atal Bihari Vajpayee Institute of Medical SciencesNew DelhiDelhiIndia

Background Hypospadias surgery has been continuously evolving,although there is no single technique which can be said to be perfect and suitable for all types of *** incised plate(TIP)urethroplasty(Snodgrass procedure)is presently the most common surgical procedure performed for distal penile hypospadias(DPH).The aim of this study was to compare the outcome of TIP urethroplasty using Dartos flap(DF)and spongioplasty as second layer in *** A total of 30 patients of DPH were repaired using TIP urethroplasty with DF or spongioplasty as second layer from January 2017 to June *** of 30 patients,TIP with DF was done in 15 patients(group A)and TIP with spongioplasty was done in the remaining 15 patients(group B).Preoperative mean age and weight were comparable in both *** complications,namely,postoperative edema,residual chordee,urethrocutaneous fistula(UCF),meatal stenosis and final cosmesis,were *** In both groups,complications included postoperative edema(Gp A-1Gp B-1),residual chordee(Gp A-1,Gp B-1),UCF(Gp A-3,Gp B-4),meatal stenosis(Gp A-1,Gp B-5)and poor cosmesis(Gp A-3,Gp B-4).Wound infection was managed with appropriate antibiotics,and meatal stenosis responded to calibration in five *** it seems that DF has a better outcome clinically,the difference between the two techniques was statistically not *** DF as an additional cover to TIP is associated with an acceptable complication and has good cosmesis compared with spongioplasty;however,the difference is not statistically significant.

关键词： edema Snodgrass distal

Strategic insights of telehealth platforms and strengths,weaknesses,opportunities,and threats analysis of Amazon's clinical endeavors

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World Journal of Methodology 2025年第2期15卷 145-153页

作者： Harpreet Grewal Gagandeep Dhillon Venkata Buddhavarapu Ram Kishun verma Ripudaman Singh Munjal Pranjal Sharma Gurmanpreet Sidhu Rahul Kashyap Salim Surani Department of Radiology Ascension Sacred Heart HospitalPensacolaFL 32503United States Department of Medicine UM Baltimore Washington Medical CenterGlen BurnieMD 21061United States Department of Medicine Banner Baywood Medical CenterBanner HealthMesaAZ 85206United States Department of Sleep Medicine Parkview Health SystemFort WayneIN 46845United States Department of Medicine Touro university College of Osteopathic MedicineVallejoCA 94592United States Department of Nephrology Northeast Ohio Medical CenterRootstownOH 44272United States Department of Pathology Government Medical College PatialaPatiala 147001PunjabIndia Department of Research Wellspan HealthYorkPA 17403United States Division of Pulmonary and Critical Care Medicine Mayo ClinicRochesterMN 55905United States Department of Medicine&Pharmacology Texas A&M UniversityCollege StationTX 77843United States

BACKGROUND The adoption of telehealth services surged after the coronavirus disease 2019 pandemic,revolutionizing traditional healthcare delivery *** Clinic's recent nationwide launch marks a significant milestone in this *** study aims to offer a strengths,weaknesses,opportunities,and threats(SWOT)analysis of Amazon Clinic and compare its features with leading virtual healthcare *** To evaluate Amazon Clinic's telehealth services through a SWOT analysis and compare its features with other leading virtual healthcare *** The initial search terms included were,amazon clinic odds ratio(OR)amwell OR Teladoc OR Walmart virtual health service OR CVS minute clinic OR CirrusMD OR brightside health,from 2000 to *** search yielded 111 articles,from which duplicates were removed,and unrelated titles were filtered *** articles were retained for a final review,including comparative studies,usability research,retrospective analyses,observational studies,and review *** data was organized and analyzed using Rayyan software and summarized in a table and PRISMA *** The review included eight articles focusing on various aspects of *** studies highlighted differences between Teladoc and traditional physician offices,noting lower diagnostic imaging orders and antibiotic prescriptions for *** demographics for Teladoc showed younger,less engaged *** studies emphasized the importance of website design for telemedicine ***-mental health platforms like Brightside showed superior outcomes in treating depression compared to traditional *** for specialized fields like skin reconstruction demonstrated cost efficiency and reduced waiting *** SWOT analysis identified Amazon Clinic's strengths,such as its vast consumer base and transparent pricing,and weaknesses like the lack of pediatric *** included potential partnerships and servi

关键词： Tele-health Amazon COVID-19 Primary Care Outpatient clinic SWOT Telemedicine

Predictors of cerebrospinal fluid GeneXpert MTB/RIF positivity in patients with tuberculous meningitis:A prospective cohort study

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Asian Pacific Journal of Tropical Medicine 2024年第10期17卷 465-472页

作者： Priyanka Gupta Neeraj Kumar Ravindra Kumar Garg Hardeep Singh Malhotra Imran Rizvi Rajesh verma Praveen Kumar Sharma Ravi Uniyal Shweta Pandey amita Jain Parul Jain Department of Neurology King George’s Medical UniversityLucknowIndia Department of Microbiology King George’s Medical UniversityLucknowIndia

Objective:To identify the clinical,laboratory,and radiological markers that could predict a positive GeneXpert result in patients suspected of tuberculous ***:In this prospective,observational study,patients with tuberculous meningitis were systematically *** clinical,laboratory[including cerebrospinal fluid(CSF)microscopy,culture,and GeneXpert],and neuroimaging factors were *** participants were administered anti-tuberculous treatment and corticosteroids.A six-month follow-up was done to evaluate the ***:Of the 116 patients studied,54(46.6%)tested positive for GeneXpert,while 62(53.4%)were *** cranial nerve involvement(OR 3.71,95%CI 1.052-13.09,P=0.04)and the presence of basal exudates on neuroimaging(OR 5.22,95%CI 2.03-13.42,P=0.001)emerged as independent predictive factors for a positive GeneXpert result.A positive CSF GeneXpert result(P=0.002)and drug resistance(P=0.004)were significantly linked to adverse ***,a high score on the Medical Research Council stageⅢ(OR 5.64,95%CI 1.18-26.87,P=0.03)and elevated CSF cell counts(OR 1.002,95%CI 1.00-1.001,P=0.03)were identified as independent predictors of poor ***:Third cranial nerve involvement and the presence of basal exudates were significant indicators of a positive GeneXpert *** stageⅢdisability and elevated CSF cell counts predicted poor outcomes.

关键词： Tuberculous meningitis Mycobacterium tuberculosis Cerebrospinal fluid Ziehl-Neelsen staining GeneXpert

Fuzzy least brain storm optimization and entropy-based Euclidean distance for multimodal vein-based recognition system

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Journal of Central South University 2017年第10期24卷 2360-2371页

作者： Dipti verma Sipi Dubey Department of CSE Vishwavidyalaya Engineering CollegeLakhanpurSarguja UniversityChhattisgarh 497001India Department of CSE Rungta College of Engineering and Technology(RCET)BhilaiChhattisgarh 490024India

Nowadays, the vein based recognition system becomes an emerging and facilitating biometric technology in the recognition system. Vein recognition exploits the different modalities such as finger, palm and hand image for the person identification. In this work, the fuzzy least brain storm optimization and Euclidean distance(EED) are proposed for the vein based recognition system. Initially, the input image is fed into the region of interest(ROI) extraction which obtains the appropriate image for the subsequent step. Then, features or vein pattern is extracted by the image enlightening, circular averaging filter and holoentropy based thresholding. After the features are obtained, the entropy based Euclidean distance is proposed to fuse the features by the score level fusion with the weight score value. Finally, the optimal matching score is computed iteratively by the newly developed fuzzy least brain storm optimization(FLBSO) algorithm. The novel algorithm is developed by the least mean square(LMS) algorithm and fuzzy brain storm optimization(FBSO). Thus, the experimental results are evaluated and the performance is compared with the existing systems using false acceptance rate(FAR), false rejection rate(FRR) and accuracy. The performance outcome of the proposed algorithm attains the higher accuracy of 89.9% which ensures the better recognition rate.

关键词： multimodality brain storm optimization (BSO) least mean square (LMS) score level fusion recognition

Modeling the effect of time delay in implementation of mitigation policies on the control of atmospheric greenhouse gases

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International Journal of Biomathematics 2023年第8期16卷 75-108页

作者： Alok Kumar verma Maitri verma Department of Mathematics School of Physical and Decision Science Babasaheb Bhimrao Ambedkar University Lucknow India

Mitigation of the enhanced greenhouse gas(GHG)concentrations in the Earth's atmosphere is imperative to meet the climate change mitigation *** of many countries are developing and implementing various mitigation strategies to reduce their GHG ***,a time delay between the formulation and implementation of these mitigation policies can affect their effectiveness in controlling greenhouse gas levels in the *** work presents a nonlinear mathematical model to investigate the effect of application of mitigation strategies and the delay involved in their implementation over the reduction of atmospheric greenhouse *** model formulation,it is assumed that the mitigation strategies work two-fold;first they reduce the GHG emission rate from the anthropogenic source and second they increase the removal rate of greenhouse gas from the atmosphere.A comprehensive stability analysis of the proposed model system is made to examine its long-term *** model analysis shows that an increase in the implementation rate of mitigation strategies and their efficiencies to cut down the GHG emission rate from point sources and increase the GHG uptake rate lead to reduction in equilibrium GHG *** is found that a long delay in the execution of mitigation policies can destabilize the system dynamics and leads to the generation of periodic *** expression for the threshold value of the delay parameter at which periodic oscillations arise via Hopf-bifurcation is *** stability and direction of bifurcating periodic solutions are discussed.A sensitivity analysis is performed to investigate the effect of changes in key parameters over system dynamics.

关键词： Mathematical model greenhouse gases global warming mitigation strategies time delay Hopf-bifurcation