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Defence Technology（防务技术） 2019年第6期15卷 923-935页

作者： Chithajalu Kiran Sagar Tarun kumar Amrita Priyadarshini amit kumar gupta Mechanical Engineering Department BITS-PilaniHyderabad Campus

Tungsten heavy alloys have come up as one of the best alternatives for high density fragmenting devices and armor piercing *** is mandatory for obtaining the final shapes of such kind of ***,due to high density and elastic stiffness of WHAs,cutting forces will be higher than for most of the metals and alloys;thus,making the machining operation *** machining variable,namely,cutting force components are significantly influenced by the cutting *** paper makes use of Oxley’s predictive analytical model in conjunction with Johnson-Cook constitutive equation to predict forces under different speed and feed combinations during machining of 95 W tungsten heavy *** cutting forces,so predicted by Ml,are considered as input data for the optimization of cutting parameters(cutting speed and feed)using Response Surface Method(RSM).

关键词： Tungsten heavy alloy Machinability Response surface method Oxley’s method

Metallurgical Studies of Austenitic Stainless Steel 304 under Warm Deep Drawing

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Journal of Iron and Steel Research International 2014年第12期21卷 1147-1151页

作者： Jayahari Lade Balu Naik Banoth amit kumar gupta Swadesh kumar Singh Department of Mechanical Engineering GRIETBachupallyHyderabad 500090TelanganaIndia Department of Mechanical Engineering JNTUHHyderabad 500085TelanganaIndia Mechanical Engineering Department BITS-PilaniHyderabad CampusHyderabad 500078TelanganaIndia

Austenitic stainless steel 304 was deep drawn with different blank diameters under warm conditions using 20 t hydraulic press. A number of deep drawing experiments both at room temperature and at 150 ℃ were conducted to study the metallography. Also, tensile test experiments were conducted on a universal testing machine up to 700 ℃ and the broken specimens were used to study the fractography of the material using scanning electron microscopy in various regions. The microstructure changes were observed at limiting draw ratio （LDR） when the cup is drawn at different temperatures. In austenitic stainless steel, martensite formation takes place that is not only affected by temperature, hut also influenced by the rate at which the material is deformed. In austenitic stainless steel 304, dynamic strain regime appears above 300 ℃ and it decreases the formability of material due to brittle fracture as studied in its fractography. From the metallographic studies, the maximum LDR of the material is observed at 150 ℃ before dynamic strain regime. It is also observed that at 150 ℃, grains are coarse in the drawn cups at LDR.

关键词： metal forming microstrueture stainless steel warm deep drawing

Influence of material models on theoretical forming limit diagram prediction for Ti-6Al-4V alloy under warm condition

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Transactions of Nonferrous Metals Society of China 2016年第3期26卷 736-746页

作者： Nitin KOTKUNDE Sashank SRINIVASAN Geetha KRISHNA amit kumar gupta Swadesh kumar SINGH Department of Mechanical Engineering Birla Institute of Technology and Science-PilaniHyderabad CampusHyderabad 500078TelanganaIndia Department of Mechanical Engineering Gokaraju Rangaraju Institute of Engineering and TechnologyHyderabad 500072TelanganaIndia

Forming limit diagram (FLD) is an important performance index to describe the maximum limit of principal strains that can be sustained by sheet metals till to the onset of localized necking. It offers a convenient and useful tool to predict the forming limit in the sheet metal forming processes. In the present study, FLD has been determined experimentally for Ti?6Al?4V alloy at 400 °C by conducting a Nakazima test with specimens of different widths. Additionally, for theoretical FLD prediction, various anisotropic yield criteria (Barlat 1989, Barlat 1996, Hill 1993) and different hardening models viz., Hollomon power law (HPL), Johnson?Cook (JC), modified Zerilli–Armstrong (m-ZA), modified Arrhenius (m-Arr) models have been developed. Theoretical FLDs have been determined using Marciniak and Kuczynski (M?K) theory incorporating the developed yield criteria and constitutive models. It has been observed that the effect of yield model is more pronounced than the effect of constitutive model for theoretical FLDs prediction. However, the value of thickness imperfection factor (f0) is solely dependent on hardening model. Hill (1993) yield criterion is best suited for FLD prediction in the right hand side region. Moreover, Barlat (1989) yield criterion is best suited for FLD prediction in left hand side region. Therefore, the proposed hybrid FLD in combination with Barlat (1989) and Hill (1993) yield models with m-Arr hardening model is in the best agreement with experimental FLD.

关键词： Ti-6Al-4V alloy yield criteria hardening model Marciniak and Kuczynski theory forming limit diagram

Clinical outcome of orbital apex syndrome in COVID associated mucormycosis patients in a tertiary care hospital

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International Journal of Ophthalmology(English edition) 2022年第4期15卷 527-532页

作者： Smiti Rani Srivastava Purban Ganguly Debasis Barman Sudip Das Manimoy Bandyopadhyay Asim kumar Ghosh Subhra Sarkar amitabha Sengupta Sarbari Swaika Pritam Chatterjee amit kumar gupta Alok Ranjan Mondal Soumyajit Guha Sinjita Dutta Souvik Adhikari Aditi Kaushik Partha Sundar Biswas Asif Ayub Department of Ophthalmology Institute of Post Graduate Medical Education and Research and Seth Sukhlal Karnani Memorial HospitalKolkata 999008India

AIM: To share clinical pattern of presentation, the modalities of surgical intervention and the one month postsurgical outcome of rhino-orbito-mucormycosis(ROCM) ***: All COVID associated mucormycosis(CAM) patients underwent comprehensive multidisciplinar y examination by ophthalmologist, otorhinolaryngologist and physician. Patients with clinical and radiological evidence of orbital apex involvement were included in the study. Appropriate medical and surgical intervention were done to each patient. Patients were followed up one-month post intervention. RESULTS: Out of 89 CAM patients, 31(34.8%) had orbital apex syndrome. Sixty-six(74.2%) of such patients had pre-existing diabetes mellitus, 18(58%) patients had prior documented use of steroid use, and 55(61.8%) had no light perception(LP) presenting vision. Blepharoptosis, proptosis, complete ophthalmoplegia were common clinical findings. Seventeen(19.1%) of such patients had variable amount of cavernous sinus involvement. Endoscopic debridement of paranasal sinuses and orbit with or without eyelid sparing limited orbital exenteration was done in most cases, 34(38.2%) patients could retain vision in the affected eye. CONCLUSION: Orbital apex involvement in CAM patients occur very fast. It not only leads to loss of vision but also sacrifice of the eyeball, orbital contents and eyelids. Early diagnosis and prompt intervention can preserve life, vision and spare mutilating surgeries.

关键词： rhino-orbito-cerebral mucormycosis COVID associated mucormycosis orbital exenteration endoscopic paranasal sinus debridement orbital apex syndrome

Intricacies during pregnancy with gestational diabetes mellitus

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World Journal of Clinical Cases 2025年第1期13卷 62-64页

作者： Richa Rattan Rimesh Pal Parul Chawla gupta Arvind kumar Morya Ripunjay Prasad Department of Endocrinology Post Graduate Institute of Medical Education and ResearchChandigarh 160012India Department of Ophthalmology Post Graduate Institute of Medical Education and ResearchChandigarh 160012PunjabIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Ophthalmology RP Eye InstituteDelhi 110001India

The study by Cao et al aimed to identify early second-trimester biomarkers that could predict gestational diabetes mellitus(GDM)development using advanced proteomic techniques,such as Isobaric tags for relative and absolute quantitation isobaric tags for relative and absolute quantitation and liquid chromatography-mass spectrometry liquid chromatography-mass *** analysis revealed 47 differentially expressed proteins in the GDM group,with retinol-binding protein 4 and angiopoietin-like 8 showing significantly elevated serum levels compared to *** these findings are promising,the study is limited by its small sample size(n=4 per group)and lacks essential details on the reproducibility and reliability of the protein quantification methods ***,the absence of experimental validation weakens the interpretation of the protein-protein interaction network identified through bioinformatics *** study's focus on second-trimester biomarkers raises concerns about whether this is a sufficiently early period to implement preventive interventions for *** GDM risk during the first trimester or pre-conceptional period may offer more clinical *** its limitations,the study presents valuable insights into potential GDM biomarkers,but larger,well-validated studies are needed to establish their predictive utility and generalizability.

关键词： Gestational diabetes mellitus Biomarkers Differentially expressed proteins Retinol-binding protein 4 Angiopoietin-like 8 Proteomics Lifestyle interventions Early prediction

Two-Dimensional Lattice Boltzmann Model for Droplet Impingement and Breakup in Low Density Ratio Liquids

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Communications in Computational Physics 2011年第8期10卷 767-784页

作者： amit gupta Ranganathan kumar Department of Mechanical Engineering Indian Institute of TechnologyNew DelhiIndia 110016 Department of Mechanical Materials and Aerospace EngineeringUniversity of Central FloridaOrlandoFL 32816USA

A two-dimensional lattice Boltzmann model has been employed to simulate the impingement of a liquid drop on a dry *** a range of Weber number,Reynolds number and low density ratios,multiple phases leading to breakup have been *** analytical solution for breakup as function of Reynolds and Weber number based on the conservation of energy is shown to match well with the *** the moment breakup occurs,the spread diameter is maximum;it increases with Weber number and reaches an asymptotic value at a density ratio of *** breakup is found to be more viable for the case when the wall is non-wetting or neutral as compared to a wetting *** breakup,the distance between the daughter droplets is much higher for the case with a non-wetting wall,which illustrates the role of the surface interactions in the outcome of the impact.

关键词： Lattice Boltzmann droplet impingement spread factor breakup

Ayurveda and in silico Approach: A Challenging Proficient Confluence for Better Development of Effective Traditional Medicine Spotlighting Network Pharmacology

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Chinese Journal of Integrative Medicine 2023年第5期29卷 470-480页

作者： Rashmi Sahu Prashant kumar gupta amit Mishra Awanish kumar Department of Balroga Shri NPA Govt.Ayurveda CollegeRaipur(492010)ChhattisgarhIndia Ayurinformatics Lab Department of KaumarabhrityaAll India Institute of AyurvedaSarita ViharNew Delhi(110076)India Cellular and Molecular Neurobiology Unit Indian Institute of TechnologyJodhpur(342037)RajasthanIndia Department of Biotechnology National Institute of TechnologyRaipur(492010)ChhattisgarhIndia

Coalescence of traditional medicine Ayurveda and in silico technology is a rigor for supplementary development of future-ready effective traditional medicine. Ayurveda is a popular traditional medicine in South Asia, emanating worldwide for the treatment of metabolic disorders and chronic illness. Techniques of in silico biology are not much explored for the investigation of a variety of bioactive phytochemicals of Ayurvedic herbs. Drug repurposing, reverse pharmacology, and polypharmacology in Ayurveda are areas in silico explorations that are needed to understand the rich repertoire of herbs, minerals, herbo-minerals, and assorted Ayurvedic formulations. This review emphasizes exploring the concept of Ayurveda with in silico approaches and the need for Ayurinformatics studies. It also provides an overview of in silico studies done on phytoconstituents of some important Ayurvedic plants, the utility of in silico studies in Ayurvedic phytoconstituents/formulations, limitations/challenges, and prospects of in silico studies in Ayurveda. This article discusses the convergence of in silico work, especially in the least explored field of Ayurveda. The focused coalesce of these two domains could present a predictive combinatorial platform to enhance translational research magnitude. In nutshell, it could provide new insight into an Ayurvedic drug discovery involving an in silico approach that could not only alleviate the process of traditional medicine research but also enhance its effectiveness in addressing health care.

关键词： Ayurveda in silico approach conﬂuence challenge effective therapeutics

Humans and Robots: A Mutually Inclusive Relationship in a Contagious World

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International Journal of Automation and computing 2021年第2期18卷 185-203页

作者： Akash gupta Anshuman Singh Deepak Bharadwaj amit kumar Mondal Department of Mechanical Engineering University of Petroleum and Energy StudiesDehradun 248007India Department of Systems Engineering University of MarylandCollege ParkMaryland 20742USA Department of Mechatronics Engineering Manipal Academy of Higher EducationDubai 345050UAE

The coronavirus global pandemic has spread faster and more severely than experts had *** this has presented itself as a great challenge,researchers worldwide have shown ingenuity and dexterity in adapting technology and devising new strategies to combat this ***,implementing these strategies alone impedes the nature of everyone′s daily ***,an intersection between these strategies and the technological advantages of robotics,artificial intelligence,and autonomous systems is essential for near-to-normal *** this review paper,different applications of robotic systems,various aspects of modern technologies,including medical imaging,telemedicine,and supply chains,have been covered with respect to the COVID-19 ***,concerns over user′s data privacy,job losses,and legal aspects of the implementation of robotics are also been discussed.

关键词： COVID-19 coronavirus telepresence delivery robots medical robots

Blumgart's technique of pancreaticojejunostomy: Analysis of safety and outcomes

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Hepatobiliary & Pancreatic Diseases International 2019年第2期18卷 181-187页

作者： Vishal gupta Saket kumar Vivek gupta Pradeep Joshi Rahul Rahul Rakesh kumar Yadav amit Dangi Abhijit Chandra Department of Surgical Gastroenterology King George's Medical University Department of Human Organ Transplant King George's Medical University

Background: Blumgart's pancreaticojejunostomy(PJ) has been described with low pancreatic leak rates. This study aimed to evaluate our experience with this technique regarding the pancreatic leak and other perioperative outcomes. Methods: We performed a single-center retrospective analysis of a cohort of 81 patients who underwent pancreaticoduodenectomy in our department from January 2011 to February 2018. The primary endpoint was the occurrence of a clinically relevant postoperative pancreatic fistula(CR-POPF) and analysis of its risk factors. Results: The CR-POPF rate was 12.3%. Fistula risk score(FRS) was the only significant risk factor for the occurrence of overall POPF in multivariate analysis. However, none of the other factors including FRS was found to be significantly associated with CR-POPF risk. A strong positive correlation was found between the CR-POPF and the incidence of delayed gastric emptying, post-pancreatectomy hemorrhage and increased length of hospital stay. Conclusion: Blumgart's technique is a safe technique of pancreatico-enteric anastomosis with low rates of CR-POPF. CR-POPF with this technique is independent of most of the preoperative and intraoperative factors. Therefore, this technique can be used for all types of the pancreas with consistently good results.

关键词： Pancreaticoduodenectomy Pancreatico-jejunal anastomosis Postoperative pancreatic fistula Pancreatic leak

Bio-effects of 5th generation electromagnetic waves on organs of human beings

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Global Health Journal 2023年第4期7卷 206-211页

作者： amit Verma Vijay kumar Shipra gupta Graphic Era Hill University DehardunUttrakhand 248001India

Objectives:The uses of devices of electromagnetic waves(EMWs)are increasing day by ***,the generation of the waves is *** frequency spectrum of the generation of waves is also *** this manuscript,an analysis of the high frequency EMWs has been made by the electric fields generated due to the exposure of 5th generation(5 G)of mobile ***:Due to the emission of waves from the towers,the electric field is generated around the transmission tower of mobile *** electric fields are computed by the power of the transmission *** electric fields across the biological tissues/cells are also computed when the EMWs penetrate inside the *** electric fields are made across the organs of different depths inside the ***:The induced electric fields inside the organs of the human beings are responsible for the absorption of energy from high frequency *** absorbed amount of energy from high frequency waves may become the cause of harmful effects on the life of organs of human ***:In this manuscript,after analysis of the computed electric fields inside the organs of human beings,it is concluded that the EMWs of 5 G spectrum of mobile phone towers may more harmful for the life of organs as 4th generation(4 G)spectrum of mobile phone *** energy absorption by the 4 G spectrum is lower than 5 G spectrum due to the range of frequency of *** effects on the pancreas,retina,skin,intestine,spleen,stomach and uterus are more than low water content organs like nails,bone,teeth etc.

关键词： Fifth generation Electromagneticwaves Mobile phonetowers Bio-effects Human beings tissues Organs