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An assessment of racial differences in epidemiological, clinical and psychosocial factors among head and neck cancer patients at the time of surgery

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World journal of Otorhinolaryngology-Head and Neck Surgery 2020年第1期6卷 41-48页

作者： Anvesh Kompelli Kathleen B.Cartmell Katherine R.Sterba Anthony j.Alberg Christopher C.Xiao amit j.sood Elizabeth Garrett-Mayer Shai j.White-Gilbertson Steven A.Rosenzweig Terry A.Day Department of Otoloryngology-Head and Neck Surgery Medical University of South Carolina(MUSC)CharlestonSC29425USA College of Nursing MUSCCharlestonSC29425USA Hollings Cancer Center MUSCCharlestonSC29425USA Department of Public Health Sciences MUSCCharlestonSC29425USA Cancer Resistry Hollings Cancer CenterMUSCCharlestonSC29425USA Department of Pharmacology MUSCCharlestonSC29425USA

Objective:Racial disparities have been well characterized and African American(AA)patients have 30%lower 5-year survival rates than European Americans(EAs)for head and neck squamous carcinoma(HNSCC).This poorer survival can be attributed to a myriad of different *** purpose of this study was to characterize AA-EA similarities and differences in sociodemographic,lifestyle,clinical,and psychosocial characteristics in HNSCC patients near the time of ***:Setting:Single tertiary care ***:Thirty-nine newly diagnosed,untreated HNSCC patients(n=24 EAs,n=15 AAs)who were to undergo surgery were *** Design:Cross-sectional study Sociodemographic,lifestyle factors,and disease factors(cancer site,AjCC clinical and pathologic stage,and HPV status)were *** factors,leisure time,quality of life and social support were also assessed using validated ***:EA and AA patients were similar in the majority of sociodemographic factors *** had a higher trend toward pathologically later stage disease compared to EAs and significantly increased time to ***:EA and AA patients were similar in the majority of sociodemographic factors *** had a higher trend toward pathologically later stage disease compared to *** also had significantly increased time to treatment(P=0.05).The majority of AA patients(62%)had later stage pathologic *** were less likely to complete high school or college(P=0.01)than their EA ***,AAs were more likely to report having a gap in health insurance during the past decade(37%vs.15%).Conclusions:This preliminary study demonstrates a similar profile of demographics,clinical and psychosocial characteristics preoperatively for AAs and *** differences were AAs tending to have later pathologic stage disease,educational status,delays in treatment initiation,and gaps in health insurance.

关键词： Head and neck cancer Healthcare disparities Treatment delay Health services Quality care HPV

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Photon orbits and phase transition for Letelier AdS black holes immersed in perfect fluid dark matter

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Chinese Physics C 2024年第6期48卷 247-259页

作者： Ashima sood Md Sabir Ali j.K.Singh Sushant G.Ghosh Department of Mathematics Netaji Subhas University of TechnologyNew Delhi-110078India Centre for Theoretical Physics Jamia Millia IslamiaNew Delhi 110025India Department of Physics Mahishadal Raj CollegePurba MedinipurWest Bengal721628India Institute of Theoretical Physics&Research Center of Gravitation Lanzhou UniversityLanzhou 730000China Key Laboratory of Quantum Theory and Applications of MoE Lanzhou UniversityLanzhou 730000China Lanzhou Center for Theoretical Physics&Key Laboratory of Theoretical Physics of Gansu Province Lanzhou UniversityLanzhou 730000China Astrophysics and Cosmology Research Unit School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa

We obtain an exact solution for spherically symmetric Letelier AdS black holes immersed in perfect fluid dark matter(PFDM).Considering the cosmological constant as the positive pressure of the system and volume as its conjugate variable,we analyze the thermodynamics of our black holes in the extended phase *** to the background clouds of strings parameter(a)and the parameter endowed with PFDM(β),we analyze the Hawking temperature,entropy,and specific ***,we investigate the relationship between the photon sphere radius and phase transition for the Letelier AdS black holes immersed in *** the analysis,with a particular condition,non-monotonic behaviors are found between the photon sphere radius,impact parameter,PFDM parameter,temperature,and *** can regard the changes in both the photon sphere radius and impact parameter before and after phase transition as the order parameter;their critical exponents near the critical point are equal to the same value,1/2,similar to that in ordinary thermal *** indicates that a universal relation of gravity may exist near the critical point for a black hole thermodynamic system.

关键词： AdS black holes perfect fluid dark matter Letelier spacetime photon orbit extended phase space thermodynamics correlation of photon orbit and thermodynamics

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Electrochemical and electronic properties of nitrogen doped fullerene and its derivatives for lithium-ion battery applications

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journal of Energy Chemistry 2018年第2期27卷 528-534页

作者： Parveen sood Ki Chul Kim Seung Soon jang School of Materials Science and Engineering Georgia Institute of Technology Atlanta CA 30332-0245. USA Department of Chemical Engineering Konkuk University Seoul 05029 Republic of Korea Institute for Electronics and Nonotechnology Georgia Institute of Technology Atlanta GA 30332-0245 USA Parker H. Petit Institute for Bioengineering and Bioscience Georgia Institute of Technology Atlanta GA 30332-0245 USA

We have studied the redox potentials and electronic properties of C60 and C59N using density functional theory method. It is found that doping C60 with one nitrogen atom results in a slight increase in redox potential. Next, we have also studied C59N functionalized with various redox-active oxygen containing functional groups and strongly electron withdrawing functional groups. It is found that the intrinsic electronic structure of the molecule is the major determinant of the redox potential. Our DFT calculations show that the electron affinity to redox potential of functionalized C59N is correlated with the LUMO of the systems very well. This is the first systematic study on the redox properties and electronic structures of N-doped C60 systems.

关键词： DFT Redox potential C60 Doping Li-ion battery

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Security and QoS issues in blockchain enabled next-generation smart logistic networks:A tutorial

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Blockchain(Research and Applications) 2022年第3期3卷 46-59页

作者： Anjali Vaghani Keshav sood Shui Yu Deakin University GeelongVIC3220Australia University of Technology SydneyNSW2007Australia

The blockchain-enabled smart logistics market is expected to grow worth USD 1620 billion and at a compound annual growth rate of 62.4%.Smart logistics ensures intelligence infrastructure,logistics automation,real-time analysis of supply chain data synchronization of the logistics process,cost transparency,unbroken shipment tracking all the way down to the transportation route,*** the smart logistics domain,significant advancement and growth of the Internet of Things(IoT)sensors are ***,the connectivity of IoT systems,including Tactile Internet,without proper safeguards creates vulnerabilities that can still be deliberately or inadvertently cause *** view of this,we primarily notice two key ***,the logistics domain can be compromised by a variety of natural or man-made activities,which eventually affect the overall network ***,there are thousands of entities in the supply chain network that use extensive machine-learning algorithms in many scenarios,and they require high-power computational *** these two challenges,we note that the first concern can be addressed by adding blockchain to IoT logistic *** second issue can be addressed using *** will support 1-μs latency communications,support seamless computing at the edges of networks,and autonomously predict the best optimal location for edge *** by this,we have highlighted motivational examples to show the necessity to integrate 6G and blockchain in smart logistic ***,we have proposed a 6G and blockchain-enabled smart logistic high-level *** have presented the key intrinsic issues of this framework mainly from the security and resource management *** this paper,recent state-of-the-art advances in blockchain enabled next-generation smart logistic networks are *** have also examined why 6G and not 5G would be compatible with the smart *** have introduced five different use cases of blockcha

关键词： Blockchain Internet of Things 5G 6G Security Smart logistics

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Carbon nanotubes:Evaluation of toxicity at biointerfaces

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journal of Pharmaceutical Analysis 2019年第5期9卷 293-300页

作者： Debashish Mohanta Soma Patnaik Sanchit sood Nilanjan Das Department of Biotechnology Manav Rachna International Institute of Research Studies Faridabad Haryana India Accendere KMS New Delhi India

Carbon nanotubes (CNTs) are a class of carbon allotropes with interesting properties that make them productive materials for usage in various disciplines of nanotechnology such as in electronics equipments, optics and therapeutics. They exhibit distinguished properties viz., strength, and high electrical and heat conductivity. Their uniqueness can be attributed due to the bonding pattern present between the atoms which are very strong and also exhibit high extreme aspect ratios. CNTs are classified as singlewalled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) on the basis of number of sidewalls present and the way they are arranged spatially. Application of CNTs to improve the performance of many products, especially in healthcare, has led to an occupational and public exposure to these nanomaterials. Hence, it becomes a major concern to analyze the issues pertaining to the toxicity of CNTs and find the best suitable ways to counter those challenges. This review summarizes the toxicity issues of CNTs in vitro and in vivo in different organ systems (bio interphases) of the body that result in cellular toxicity.

关键词： Bio interphases Carbon nanotubes (CNTs) In vivo toxicity In vitro toxicity

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Foliar Application of Benzothiadiazole and Salicylic Acid to Combat Sheath Blight Disease of Rice

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Rice science 2013年第5期20卷 349-355页

作者： Neerja sood B.S.SOHAL j.S.LORE Department of Biochemistry Punjab Agricultural UniversityLudhiana-141004 India Department of Plant Breeding and Genetics Punjab Agricultural UniversityLudhiana-141004 India

A field study was undertaken to ascertain the effects of elicitors viz. benzothiadiazole （BTH） and salicylic acid （SA） on defense related enzymes viz. peroxidase, phenylalanine ammonia lyase, superoxide dismutase, chitinase and 13-1,3-glucanase, and phenols in rice （Pusa Basmati I） plants. First foliar spray of BTH （50 mg/kg） and SA （50 mg/kg） was done at the maximum tillering stage and inoculation with Rhizoctonia solani was carried 24 h after elicitor treatment. Elicitors were further sprayed at every growth stage. Time course analysis showed peak accumulation of defense related enzymes and phenols in the rice leaves treated with BTH and SA, and accumulation was the highest at the flowering stage. Higher enzymatic activity was observed in elicitor treated plants inoculated with R. solani. Compared to the untreated control plants, application of elicitors before R. solani inoculation significantly elicited the defense related enzymes and phenols. Moreover, application of elicitors had a positive effect on yield and disease reduction. It is suggested that pretreatment of rice leaves with BTH and SA could be used to enhance the level of protection against sheath blight and to improve rice yield in the fields.

关键词： Oryza sativa benzothiadiazole salicylic acid defense related enzyme phenols sheath blight foliar application

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Comparative study of CEA and CA19-9 in esophageal,gastric and colon cancers individually and in combination(ROC curve analysis)

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Cancer Biology & Medicine 2013年第3期10卷 148-157页

作者： Bhawna Bagaria Sadhna sood Rameshwaram Sharma Soniya Lalwani Department of Biochemistry S.M.S.Medical College & Hospital Department of Radiotherapy and Oncology S.M.S.Medical College & Hospital Advanced Bioinformatics Centre Birla Institute of Scientific Research

Objective： To determine the clinical serum levels of carcinoembryonic antigen （CEA） and carbohydrate antigen 19-9 （CA19-9）, individually and in combination, for the diagnosis of 50 healthy subjects and 150 cases of esophageal, gastric, and colon cancers. Methods： The sensitivities of the two markers were compared individually and in combination, with specificity set at 100%. Receiver operating characteristic （ROC） curves were plotted. Results： Serum CEA levels were significantly higher in cancer patients than in the control group. The sensitivity of CEA was determined： in esophageal cancer, sensitivity=28%, negative predictive value （NPV）=61.72%, and AUC=0.742 （SE=0.05）, with a significance level of P〈0.0001; in gastric cancer, sensitivity=30%, NPV=58.82%, and AUC=0.734 （SE=0.0S）, with a significance level of P〈0.0001; in colon cancer, sensitivity=74%, NPV=79.36%, and AUC=0.856 （SE=0.04）, with a significance level of P〈0.0001. The sensitivity of CA19-9 was also evaluated： in esophageal cancer, sensitivity=18%, NPV=54.94%, and AUC=0.573 （SE=0.05）, with a significance level of P=0.2054. In gastric cancer, sensitivity=42%, NPV=63.29%, and AUC=0.679 （SE=0.05）, with a significance level of P〈0.0011. In colon cancer, sensitivity=26%, NPV=57.47%, and AUC=0.S80 （SE=0.05）, with a significance level ofP=0.1670. The following were the sensitivities of CEA/CA19-9 combined： in esophageal cancer, sensitivity=42%, NPV=63.29%, SE=0.078 （95% CI： 0.0159-0.322）; gastric cancer, sensitivity=S8%, NPV=70.42%, SE=0.072 （9$% CI： -0.0866-0.198）; and colon cancer, sensitivity=72%, NPV=78.12%, SE=0.070 （9S% CI： 0.137-0.415）. Conclusion： CEA exhibited the highest sensitivity for colon cancer, and CA19-9 exhibited the highest sensitivity for gastric cancer. Combined analysis indicated an increase in diagnostic sensitivity in esophageal and gastric cancer compared with that in colon cancer.

关键词： Carcinoembryonic antigen carbohydrate antigen 19-9, human Receiver operating characteristic curve sensitivity andspecificity

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Guest editorial:Special issue on security and privacy for AI-powered smart IoT applications

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Digital Communications and Networks 2022年第4期8卷 411-414页

作者： Lianyong Qi jin Li Mehdi Elahi Keshav sood Yuan Yuan Mohammad Khosravi Qufu Normal University China Guangzhou University China University of Bergen Norway Deakin University Australia Beihang University China Persian Gulf University Iran

The prevalence of Internet of Things(IoT)applications has generated an unprecedented volume of industrial data that create the main source of big data[1,2].How to effectively and efficiently preprocess,integrate,and analyze big IoT data from multiple sources is still a fundamental challenge[3,4].Fortunately,Artificial Intelligence(AI)has recently emerged as a key technology to achieving intelligent data analyses and scientific business *** algorithms can process the streaming data generated by distributed IoT devices and provide powerful tools to address complex big data analytics[5,6].Therefore,the adaptation of AI-based methods is highly demanded for achieving their full potential in smart IoT ***,the IoT devices,which run in an unstable environment and have poor computing capabilities,are often confronted with a range of application requirements,such as quick response,secure communications,and privacy protection[7,8].Currently,lightweight security and privacy solutions specifically designed for the devices and servers operating in the IoT environment are still lacking.

关键词： IoT smart unstable

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Identifying genomic regions controlling ratoon stunting disease resistance in sugarcane(Saccharum spp.) clonal F_(1) population

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The Crop journal 2021年第5期9卷 1070-1078页

作者： Qian You Sushma sood Ziliang Luo Hongbo Liu Md.Sariful Islam Muqing Zhang jianping Wang State Key Lab for Conservation and Utilization of Subtropical Agric-Biological Resources Guangxi UniversityNanning 530005GuangxiChina Agronomy Department University of FloridaGainesvilleFL 32610USA USDA-ARS Sugarcane Field StationCanal PointFL 33438USA Sugarcane Research Institute Yunnan Academy of Agricultural SciencesKaiyuan 661699YunnanChina Genetics Institute&Plant Molecular and Cellular Biology Program University of FloridaGainesvilleFL 32610USA

The ratoon stunting disease (RSD) of sugarcane,caused by the bacterium Leifsonia xyli ***,is one of the major concerns to sugarcane production and breeding programs *** to no obvious external symptoms,RSD cannot be easily detected by the growers,hence has reduced the world’s sugarcane production *** study aimed to identify quantitative trait loci (QTL) associated with RSD resistance and to assist in the development of linked molecular markers for marker-assisted breeding to minimize the reduction in sugarcane yield by the RSD infection.A set of 146 individuals derived from a self-crossing of CP80-1827 were evaluated for RSD resistance in a mechanically duplicated inoculated field trial from 2014 to 2017 using tissue blot *** the genetic data and the four years phenotyping data of CP80-1827 selfing population,linkage map construction and QTL analysis were conducted based on clonal F_1 and F_2 mapping population types with GACD V.1.2 and Ici Mapping V.3.3,respectively.A total of 23 QTL associated with RSD resistance were identified,which explained 6%to13%of the phenotypic variation with the two types of software.A total of 82 disease resistance genes were identified by searching these 23 QTL regions on their corresponding regions on the Sorghum bicolor genome (44 genes),sugarcane R570 genome (20 genes),and *** genome (18 genes),*** with Ici Mapping V.3.3,GACD V.1.2 identified more major (6 vs.3) and stable QTL (2vs.0),and more disease resistance genes (51 vs.31),indicating GACD V.1.2 (clonal F_1 mapping type) is most likely to be more efficient than Ici Mapping (F_2 mapping type) for QTL analysis of a sefling population or clonal F_1 population in clonal *** identified QTL controlling RSD resistance along with the associated SNP markers will assist sugarcane molecular breeding programs in combating this disease.

关键词： Quantitative trait loci(QTL) GACD IciMapping SNP marker Sugarcaneratoon stunting disease

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Hydromagnetic unsteady slip stagnation flow of nanofluid with suspension of mixed bio-convection

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Propulsion and Power Research 2019年第4期8卷 362-372页

作者： R.Kumar S.sood C.S.K.Raju S.A.Shehzad Department of Mathematics Central University of Himachal PardeshDharamshala176215India Department of Mathematics GITAM UniversityBangalore562163KarnatakaIndia Department of Mathematics COMSATS Institute of Information TechnologySahiwal57000Pakistan

In this paper,stagnation point region(suspended with nanofluid and microorganisms)is examined subjected to velocity and thermal *** flow is assumed to be flowing across an exponentially stretching flat surface under magnetic field *** transport equations(framed under Buongiorno’s model)are converted into self-similar form through suitable unsteady exponential similarity transformations which are then solved by employing implicit finite difference scheme(IFDS)known as Keller-box method(KBM).A parametric analysis is performed along with limited details of *** of pertinent constraints on local skin friction,local Nusselt number,local Sherwood number and local density number of micro-organisms are also uncovered through graphs.A significant decrease in skin-friction coefficients has been detected with respect to thermal slip in comparison to velocity slip.

关键词： Unsteady flow Stagnation point region Mixed convection Microorganisms Nanoparticles Slip regime Keller-box scheme

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