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Excipient effect on antimicrobial activity of Cinnamon (Cinnamomum zelylanicum album) oil, Thyme (Thymus vulgaris) oil and Ajowan (Trachyspermum ammi) oil

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Infectious Diseases Research 2024年第1期5卷 27-31页

作者： Bhoj R Singh Shiv Varan Singh Ravikant agarwal Akanksha Yadav Division of Epidemiology ICAR-Indian Veterinary Research InstituteBareilly 243122India Division of Bacteriology and Mycology ICAR-Indian Veterinary Research InstituteBareilly 243122India Division of Livestock Products Technology ICAR-Indian Veterinary Research InstituteBareilly 243122India.

Background:Many herbal essential oils are potential antimicrobials but their pharmaceutical utility is restricted due to a lack of suitable excipients to mollify their dermatotoxicity and irritant property,and outcome of their therapeutic use may vary with different diluents ***:Effect of 16 diluents(dimethyl sulfoxide,liquid paraffin,glycerine,oils of mustard,sunflower,rice bran,palm,groundnut,olive,coconut,sesame,avocado,jojoba,castor,linseed and soybean)was assessed on antimicrobial activity of 2%cinnamon(Cinnamomum zelylanicum album),thyme(Thymus vulgaris)and ajowan(Trachyspermum ammi)oils using agar well diffusion *** effect of excipients was evaluated on six Candida albicans,five Escherichia coli,four Acinetobacter lwoffii,two strains each of Staphylococcus aureus,Enterobacter agglomerans,and Enterococcus faecium and one strain each of Acinetobacter calcoaceticus,Escherichia fergusonii,Klebsiella oxytoca,*** ***,Leclercia adecarboxylata,Paenibacillus amylolyticus,Proteus mirabilis,***,Pseudomonas aeruginosa,Raoultella terrigena,Staphylococcus capitis ***,***,***,*** and Streptococcus ***:Thyme oil(2%)maintained it antimicrobial activity on dilution in dimethyl sulfoxide and glycerine,and ajowan oil(2%)completely lost its antibacterial activity in all diluents except dimethyl ***,cinnamon oil partially lost its antimicrobial activity upon dilution in glycerine,vegetable,and mineral oils in comparison to dimethyl *** oil was the best vegetable oil,almost comparable to dimethyl sulfoxide and castor oil was the worst diluent for maintaining antimicrobial activity of cinnamon ***:The study indicated the non-suitability of vegetable oils for pharmaceutical formulations of essential oils except olive oil for dilution of cinnamon oil and glycerol for thyme oil to replace dimethyl sulfoxide as diluent.

关键词： essential oils herbal antimicrobials herbal drug-resistance Bacteria Candida

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Comment on: Observation of peripheral refraction in myopic anisometropia in young adults

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International Journal of Ophthalmology(English edition) 2024年第7期17卷 1385-1386页

作者： Suraj Kumar Chaurasiya Mahendra Singh Pradeep agarwal Yu-Qin Du Yue-Hua Zhou Ming-Wei Ding Ming-Xu Zhang Yu-Juan Guo Shan-Shan Ge Department of Optometry and Vision Science CL Gupta Eye InstituteRam Ganga Vihar Phase II(Extn.)MoradabadUttar Pradesh 244001India Department of Paediatric and Neuro Ophthalmology CL Gupta Eye InstituteRam Ganga Vihar Phase II(Extn.)MoradabadUttar Pradesh 244001India Eye School of Chengdu University of TCM Ineye Hospital of Chengdu University of TCMChengdu 610036Sichuan ProvinceChina Beijing Ming Vision and Ophthalmology Beijing 100010China

Dear Editor,We read with great interest the recently published article titled“Observation of peripheral refraction in myopic anisometropia in young adults”by Du et al[1].The study conducted at the InEye Hospital of Chengdu University of TCM provides valuable insights into the relationship between anisometropia and peripheral refraction in myopic young *** commend the authors for their thorough investigation and adherence to ethical *** the study contributes significantly to our understanding of myopic anisometropia,we would like to draw attention to some limitations that merit consideration for a comprehensive interpretation of the findings.

关键词： Observation young insight

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你的奖励由谁买单:信用卡市场的再分配

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新金融 2024年第1期 59-66页

作者： Sumit agarwal Andrea Presbitero Andre F.Silva Carlo Wix 新加坡国立大学国际货币基金组织经济政策研究中心美国联邦储备委员会

将信用卡奖励作为一个理想的实验进行研究,以量化零售金融市场中消费者之间的再分配。通过对有奖励和无奖励的信用卡进行比较,可以发现:无论收入如何,成熟的消费者都能从有奖励的信用卡中获利,而有的消费者则要付出代价。为了探究其背... 详细信息

将信用卡奖励作为一个理想的实验进行研究,以量化零售金融市场中消费者之间的再分配。通过对有奖励和无奖励的信用卡进行比较,可以发现:无论收入如何,成熟的消费者都能从有奖励的信用卡中获利,而有的消费者则要付出代价。为了探究其背后的机制,本文利用银行在信用卡层面主动提高账户限额的方法进行研究。结果表明:奖励卡会诱发更多的消费,使消费者有更高的未付余额;消费者在偿还信用卡时还会遵循次优平衡匹配启发模式,从而产生更高的成本;银行通过提供比无奖励的同类信用卡更低的利率来激励消费者使用奖励卡;从教育程度较低的地区到较高的地区,从较贫穷的地区到较富裕的地区,信用卡奖励以重新分配的方式扩大了现有的差距。本刊编译此篇美联储的工作论文,以期就信用卡相关问题为读者带来启发。

关键词：消费金融信用卡金融复杂性用卡奖励

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富氮气调--磷化氢的可供替换技术

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粮油食品科技 2024年第3期32卷 55-68页

作者： Manjree agarwal James NEWMAN Yan-yu LI Li GU Bei-bei LI Yong-lin REN 李燕羽(译) 西澳大利亚政府化学中心澳大利亚珀斯WA 6102 CBH澳大利亚谷物有限公司澳大利亚珀斯WA 6000 默多克大学环境和生命科学学院澳大利亚珀斯WA 6150 国家粮食和物资储备局科学研究院粮食储运研究所北京100037 国家粮食和物资储备局科学研究院粮食储运研究所

在粮食储藏上利用氮气的方法已经有30多年的历史,但直到最近经济有效的变压吸附(PSA)和膜分离(MS)制氮设备的出现,才使得该技术在储粮上使用成为可能。本研究首先在25、30和35℃、99%、98%和97%氮气的环境下,对小麦、大麦、燕麦、羽扇... 详细信息

在粮食储藏上利用氮气的方法已经有30多年的历史,但直到最近经济有效的变压吸附(PSA)和膜分离(MS)制氮设备的出现,才使得该技术在储粮上使用成为可能。本研究首先在25、30和35℃、99%、98%和97%氮气的环境下,对小麦、大麦、燕麦、羽扇豆和油菜籽中的花斑皮蠹、赤拟谷盗、谷蠹和米象成虫和非成虫虫态进行了为期4、3和2周的实验室生物测定。然后在终端用户LakeGrace和CBH(Cooperative BulkHandling)谷物进出口公司Albany出口港码头开展实仓验证,测定小麦、大麦和油菜籽中不同储粮害虫虫种和油菜籽瓢虫和肖叶甲类两种田间害虫的防治效果。同时对处理后的粮食品质进行了测定。实验结果表明,害虫死亡率随着氧气浓度降低、暴露时间和温度的增加而增加,富氮低氧在低温条件下不能100%致死花斑皮蠹幼虫。氮气处理对磷化氢抗性和敏感品系储粮害虫防治效果没有差异。与其他粮种相比,在油菜籽中的防治效果更好。各种粮种的水分含量、蛋白质、含油量、淀粉和籽粒颜色品质指标均未受到影响。成功开发了富氮低氧商业规模应用模式,为磷化氢高抗性害虫治理提供了解决方案,满足市场日益增长对无害虫和无化学残留粮食的需求。

关键词：气调储藏害虫治理磷化氢抗药性粮食品质应用模式

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Antioxidant treatment for oligoasthenoteratozoospermia and varicocele:a DBPC trial to evaluate the impact of age and body mass index

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Asian Journal of Andrology 2024年第3期26卷 239-244页

作者： Gian Maria Busetto Bernarde F Rodrigues Ashraf Virmani Andrea Checchia Antonella Ninivaggi Anna Ricapito Giovanni Barbieri Piero Fischetti Ugo G Falagario Pasquale Annese Nicola d’Altilia Vito Mancini Matteo Ferro Felice Crocetto Angelo Porreca Carlo Bettocchi Luigi Cormio Ashok agarwal Giuseppe Carrieri University of Foggia Foggia 71122Italy Department of Urology and Renal Transplantation Policlinico of FoggiaFoggia 71122Italy Department of Urology Human Reproduction SectionFederal University of Sao PauloSao Paulo 05403-000Brazil Alfasigma Healthscience Utrecht 3528 BGThe Netherlands Urology Unit “G.Tatarella”HospitalCerignola 71042Italy Urology Unit European Institute of Oncology(IEO)IRCCSMilan 20142Italy University of Naples Federico II Naples80126Italy Department of Oncological Urology Veneto Institute of Oncology(IOV)IRCCSPadua 35039Italy Urology Unit “L.Bonomo”HospitalAndria 70031Italy Global Andrology Forum Moreland HillsOH 44022USA

Oxidative stress is one of the main mechanisms responsible for male *** conditions such as varicocele,obesity,advanced age,and lifestyle can lead to an increase in reactive oxygen species,causing an oxidative imbalance in the *** are sensitive to reactive oxygen species and require energy to carry out their main function of fertilizingthe *** reactive oxygen species can affect sperm metabolism,leading to immobility,impaired acrosome reaction,and celldeath,thereby impairing reproductive *** double-blind randomized study evaluated the effect of supplementation withL-carnitine,acetyl-L-carnitine,vitamins,and other nutrients on semen quality in 104 infertile patients with or without varicocele,while also investigating the impact of factors such as obesity and advanced age on *** concentration significantlyincreased in the supplemented group compared to the placebo group(P=0.0186).Total sperm count also significantly increasedin the supplemented group(P=0.0117),as did sperm motility(P=0.0120).The treatment had a positive effect on patients upto 35 years of age in terms of sperm concentration(P=0.0352),while a body mass index(BMI)above 25 kg m^(−2) had a negativeeffect on sperm concentration(P=0.0110).Results were not showing a net benefit in stratifying patients in accordance withtheir BMI since sperm quality increase was not affected by this *** conclusion,antioxidant supplementation may bebeneficial for infertile patients and has a more positive effect on younger patients with a normal weight.

关键词： aging antioxidants body mass index oligoasthenoteratozoospermia varicocele

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富氮低氧+磷化氢防治储粮害虫技术的实仓应用研究

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粮油食品科技 2024年第3期32卷 39-54页

作者： Manjree agarwal James NEWMAN Yan-yu LI Li GU Bei-bei LI Sucharita BASAVARAJAPP Yong-lin REN 李燕羽(译) 西澳大利亚州政府化学中心澳大利亚珀斯WA 6102 CBH澳大利亚谷物有限公司澳大利亚珀斯WA 6000 默多克大学环境和生命科学学院澳大利亚珀斯WA 6150 国家粮食和物资储备局科学研究院粮食储运研究所北京100037 国家粮食和物资储备局科学研究院粮食储运研究所

为防治澳大利亚主要仓储害虫,开发富氮气调技术作为熏蒸剂的辅助手段。然而,由于成本问题,一直影响其在行业推广应用。本研究利用中国长顺安达公司的先进膜分离技术,与传统的制氮技术(变压吸附/PSA)进行性能比较,在西澳Kwinana的CBH粮食... 详细信息

为防治澳大利亚主要仓储害虫,开发富氮气调技术作为熏蒸剂的辅助手段。然而,由于成本问题,一直影响其在行业推广应用。本研究利用中国长顺安达公司的先进膜分离技术,与传统的制氮技术(变压吸附/PSA)进行性能比较,在西澳Kwinana的CBH粮食港,开展实仓应用实验,以解决阻碍其推广的运营和成本问题。为满足澳大利亚严格的标准操作条件,长顺安达专业团队对港口设备进行了升级改造,目标消杀成本设定为0.50澳元/吨粮(磷化氢的高端熏蒸成本)。研究表明,旧的PSA技术的运营成本为2.43澳元/吨粮,该技术在产生和维持控制害虫所需的99%氮气浓度水平方面也显示出操作局限性。相比之下,使用膜技术制氮的成本为0.99澳元/吨粮,其他性能增益还包括运行4.5天内即可产生所需的氮气浓度,且可维持14天以完全控制害虫。

关键词：粮食储藏储粮害虫管理氮气储藏变压吸附制氮机膜分离制氮机

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富氮气调——磷化氢的可供替换技术（中英文）

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粮油食品科技 2024年

作者： Manjree agarwal James NEWMAN Yan-yu LI Li GU Bei-bei LI Yong-lin REN 西澳化学中心珀斯 CBH澳大利亚谷物有限公司珀斯国家粮食和物资储备局科学研究院粮食储运研究所默多克大学环境与生命科学学院珀斯

在粮食储藏上利用氮气的方法已经有30多年的历史，但直到最近经济有效的变压吸附（PSA）和膜分离（MS）制氮设备的出现，才使得该技术在储粮上使用成为可能。本研究成功开发了商业规模的清洁富氮技术，为磷化氢高抗性害虫治理提供了解... 详细信息

在粮食储藏上利用氮气的方法已经有30多年的历史，但直到最近经济有效的变压吸附（PSA）和膜分离（MS）制氮设备的出现，才使得该技术在储粮上使用成为可能。本研究成功开发了商业规模的清洁富氮技术，为磷化氢高抗性害虫治理提供了解决方案，满足市场日益增长对无害虫和无化学残留粮食的需求。默多克大学收获后植物生物安全实验室开展了富氮应用技术的研究，并与终端用户合作开展实仓验证，如Lake Grace (33°06′00″S 118°27′40″E)农场储存仓和CBH（Cooperative Bulk Handling）谷物进出口公司Albany 出口港码头（35°1′50.90″S 117°53′0.54″E）仓房。

关键词：粮食储藏储粮害虫治理储粮害虫抗药性气调储藏变压吸附制氮机膜分离制氮机

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An Adaptive Genetic Algorithm-Based Load Balancing-Aware Task Scheduling Technique for Cloud Computing

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Computers, Materials & Continua 2022年第12期73卷 6103-6119页

作者： Mohit agarwal Shikha Gupta Deptartment of Computer Science&Engineering School of Engineering&TechnologySharda UniversityGreater NoidaUttar Pradesh201319India Department of Information Technology Maharaja Agrasen Institute of TechnologyDelhi110086India

Task scheduling in highly elastic and dynamic processing environments such as cloud computing have become the most discussed problem among *** scheduling algorithms are responsible for the allocation of the tasks among the computing resources for their execution,and an inefficient task scheduling algorithm results in under-or over-utilization of the resources,which in turn leads to degradation of the ***,in the proposed work,load balancing is considered as an important criterion for task scheduling in a cloud computing environment as it can help in reducing the overhead in the critical decision-oriented *** this paper,we propose an adaptive genetic algorithm-based load balancing(GALB)-aware task scheduling technique that not only results in better utilization of resources but also helps in optimizing the values of key performance indicators such as makespan,performance improvement ratio,and degree of *** concept of adaptive crossover and mutation is used in this work which results in better adaptation for the fittest individual of the current generation and prevents them from the *** simulator has been used to carry out the simulations and obtained results establish that the proposed GALB algorithm performs better for all the key indicators and outperforms its peers which are taken into the consideration.

关键词： Cloud computing genetic algorithm(GA) load balancing makespan resource utilization task scheduling

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Neuroprotective effects of exogenous brain-derived neurotrophic factor on amyloid-beta 1-40-induced retinal degeneration

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Neural Regeneration Research 2023年第2期18卷 382-388页

作者： Mohd Aizuddin Mohd Lazaldin Igor Iezhitsa Renu agarwal Puneet agarwal Nafeeza Mohd Ismail Department of Biosciences Faculty of ScienceUniversiti Teknologi MalaysiaJohor BahruMalaysia School of Medicine International Medical UniversityKuala LumpurMalaysia Department of Pharmacology and Bioinformatics Volgograd State Medical UniversityVolgogradRussia Faculty of Medicine Universiti Teknologi MARASungai Buloh CampusSelangorMalaysia

Amyloid-beta(Aβ)-related alterations,similar to those found in the brains of patients with Alzheimer's disease,have been observed in the retina of patients with *** levels of brain-derived neurotrophic factor(BDNF)are believed to be associated with the neurotoxic effects of Aβ*** investigate the mechanism underlying the neuroprotective effects of BDNF on Aβ_(1-40)-induced retinal injury in Sprague-Dawley rats,we treated rats by intravitreal administration of phosphate-buffered saline(control),Aβ_(1-40)(5 nM),or Aβ_(1-40)(5 nM)combined with BDNF(1μg/mL).We found that intravitreal administration of Aβ_(1-40)induced retinal ganglion cell ***-Gold staining showed a significantly lower number of retinal ganglion cells in the Aβ_(1-40)group than in the control and BDNF *** the Aβ_(1-40)group,low number of RGCs was associated with increased caspase-3 expression and reduced TrkB and ERK1/2 *** abolished Aβ_(1-40)-induced increase in the expression of caspase-3 at the gene and protein levels in the retina and upregulated TrkB and ERK1/2 *** findings suggest that treatment with BDNF prevents RGC apoptosis induced by Aβ_(1-40)by activating the BDNF-TrkB signaling pathway in rats.

关键词： amyloid-beta 1-40 brain-derived neurotrophic factor Fluoro-Gold neuroprotection retinal ganglion cells(RGC) retinal toxicity tropomyosin receptor kinase B(TrkB)

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Hirschsprung's disease:Is there a relationship between mast cells and nerve fibers?

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World Journal of Gastroenterology 2009年第12期15卷 1493-1498页

作者： amit Kumar Yadav Kiran Mishra Anup Mohta Sarla agarwal Department of Pathology University College of Medical SciencesNew Delhi 110095India Department of Paediatric Surgery Chacha Nehru Baal ChikitsalyaNew Delhi 110095India

AIM:To define the topography of mast cells and their numbers in cases of Hirschsprung's disease(HD)and non-HD,assess neural hypertrophy using imaging software and to study the relationship between mast cells and nerve ***:HE stained sections of 32 cases of chronic constipation in the age group of 0-14 years were reviewed for ganglion *** staining was performed on frozen sections of colonic and rectal *** on their findings cases were divided into HD and non-HD and mast cells stained by toluidine blue were *** analysis by computerized software was applied to S-100 stained sections for assessment of neural ***:Difference between number of mast cells in HD group(mean=36.44)and in non-HD group(mean =14.79)was statistically *** analysis morphometry on S-100 stained sections served as a useful *** difference between number,size,and perimeter of the nerve fibers between HD and non-HD group was statistically ***:Mast cells are significantly increased in HD and their base line values are much higher in Indian children than that reported in Western *** role in HD needs further *** of S-100 stained nerve fibers is a useful adjunct to conventional methods for diagnosis of HD.

关键词：先天性巨结肠症肥大细胞神经纤维乙酰胆碱酯酶染色计算机图像分析神经节细胞慢性便秘直肠活检

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