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World Journal of Orthopedics 2016年第7期7卷 426-433页

作者： Raju Vaishya Vipul Vijay Vikas P Birla amit K agarwal Department of Orthopaedics Joint Replacement and ArthroscopyIndraprastha Apollo Hospital

AIM: To compare the postoperative mechanical alignment achieved after total knee arthroplasty(TKA) using computer tomography(CT) based patient specific blocks(PSB) to conventional instruments(CI).METHODS: Total 80 knees were included in the study, with 40 knees in both the groups operated using PSB and CI. All the knees were performed by a single surgeon using the same cruciate sacrificing implants. In our study we used CT based PSB to compare with CI. Postoperative mechanical femoro-tibial angle(MFT angle) was measured on long leg x-rays using picture archiving and communication system(PACS). We compared mechanical alignment achieved using PSB and CI in TKA using statistical ***: The PSB group(group 1) included 17 females and seven males while in CI group(group 2) there were 15 females and eight males. The mean age of patients in group 1 was 60.5 years and in group 2 it was 60.2 years. The mean postoperative MFT angle measured on long-leg radiographs in group 1 was 178.23°(SD = 2.67°, range: 171.9° to 182.5°) while in group 2, the mean MFT angle was 175.73°(SD = 3.62°, range: 166.0° to 179.8°). There was significant improvement in postoperative mechanical alignment(P value = 0.001), in PSB group compared to CI. Number of outliers were also found to be less in group operated with PSB(7 Knee) compared to those operated with CI(17 Knee).CONCLUSION: PSB improve mechanical alignment after total knee arthroplasty, compared to CI. This may lead to lower rates of revision in the PSB based TKA as compared to the conventional instrumentation.

关键词： Knee Replacement Arthroplasty Patient specific jigs Conventional jigs

EPASAD:ellipsoid decision boundary based Process-Aware Stealthy Attack Detector

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Cybersecurity 2024年第3期7卷 32-48页

作者： Vikas Maurya Rachit agarwal Saurabh Kumar Sandeep Shukla Department of Computer Science and Engineering Indian Institute of Technology KanpurkanpurIndia Merkle Science BangaloreIndia

Due to the importance of Critical Infrastructure(Cl)in a nation's economy,they have been lucrative targets for cyber *** critical infrastructures are usually Cyber-Physical Systems such as power grids,water,and sewage treatment facilities,oil and gas pipelines,*** recent times,these systems have suffered from cyber attacks numer-ous *** have been developing cyber security solutions for Cls to avoid lasting *** to standard frameworks,cyber security based on identification,protection,detection,response,and recovery are at the core of these *** of an ongoing attack that escapes standard protection such as firewall,anti-virus,and host/network intrusion detection has gained importance as such attacks eventually affect the physical dynamics of the ***,anomaly detection in physical dynamics proves an effective means to implement *** is one example of anomaly detection in the sensor/actuator data,representing such systems physical *** present EPASAD,which improves the detection technique used in PASAD to detect these micro-stealthy attacks,as our experiments show that PASAD's spherical boundary-based detection fails to *** method EPASAD overcomes this by using Ellipsoid boundaries,thereby tightening the boundaries in various dimen-sions,whereas a spherical boundary treats all dimensions *** validate EPASAD using the dataset produced by the TE-process simulator and the C-town *** results show that EPASAD improves PASAD's average recall by 5.8%and 9.5%for the two datasets,respectively.

关键词： Intrusion detection system Critical infrastructure security Industrial control system Machine learning

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高效的模块选择,实现低功耗设计

中国集成电路 2015年第8期24卷 17-20页

作者： Gaurav Gupta amit agarwal Syed Shakir Iqbal 飞思卡尔半导体印度公司

1介绍数字设计工具包（DDK）是So C开发的基本构件。如今技术团队增加越来越多的创新风格的标准模块,使So C设计人员很难选择最合适款型的标准模块来实现面积、速度和So C功能方面的目标。根据摩尔定律,集成电路中的晶体管的数量几乎以... 详细信息

1介绍数字设计工具包（DDK）是So C开发的基本构件。如今技术团队增加越来越多的创新风格的标准模块,使So C设计人员很难选择最合适款型的标准模块来实现面积、速度和So C功能方面的目标。根据摩尔定律,集成电路中的晶体管的数量几乎以每两年翻一倍的速度增长。但技术的发展经常超越摩尔定律。此外,So C开发还希望能够在18个月的时间内使芯片性能翻倍。

关键词：摩尔定律技术团队低功耗设计基本构件沟道长度数字设计设计过程数据通路测试用例内使

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为减缓气候变化能源效率需经济可行

世界钢铁 2014年第2期14卷 58-63页

作者： Shibojyoti Dutta amit agarwal Dillip Kumar Behera 何海良塔塔钢铁公司

印度的钢材消耗继续落后于世界上其他国家。为适应经济的发展,到2020年,印度的钢材需求量每年最少为1.5亿2亿t。当前,印度年钢产量约6 000万t,到2020年,年产量预计将达到2.75亿t。尽管采取有效的工艺可以减少CO2的排放强度,但预计其排... 详细信息

印度的钢材消耗继续落后于世界上其他国家。为适应经济的发展,到2020年,印度的钢材需求量每年最少为1.5亿2亿t。当前,印度年钢产量约6 000万t,到2020年,年产量预计将达到2.75亿t。尽管采取有效的工艺可以减少CO2的排放强度,但预计其排放量仍会升高。现有技术存在着经济性与适应性的挑战。例如,干熄焦技术有助于余热的利用,但新建焦炉的成本高是一个障碍,与此同时,现有焦炉也面临着大修的挑战。这些不利之处在大部分余热回收与能源效率项目中始终存在。为保证生产的连续性,关键需要额外的发电能力或配备强劲的电网,这些都与投资相关,因为其常常限制余热回收技术的实施。为紧急应对全球的气候变化,减少CO2排放,正在开发一些新项目。除了从熔渣中回收余热、低温余热资源、碳中性钢冶炼工艺之外,包括碳捕集与贮存也在考虑之列。与电厂锅炉排出的废气相比,高炉荒煤气中含有温度低、含量高的CO2,从中进行碳捕集相对来说更为经济。因此,加快开发与应用高炉的碳捕集与贮存技术具有财务上的激励作用,对印度钢铁业的增长而言,具有可以缓解气候变化的潜力。这些技术的应用在短中期内不利于公司的生存,但为了缓解气候变化和行业长期的可持续性,这些措施势在必行。因此,为保证能及时采用这些技术,总的工作计划需要确保其:①经济上能够承受;②能及时获取;③能够克服技术改造带来的挑战。

关键词：气候变化铁钢效率余热回收碳贸易

Identifying the stability of housekeeping genes to be used for the quantitative real-time PCR normalization in retinal tissue of streptozotocin-induced diabetic rats

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 794-805页

作者： Muhammad Zulfiqah Sadikan Nurul Alimah Abdul Nasir Mohammad Johari Ibahim Igor Iezhitsa Renu agarwal Department of Pharmacology Faculty of MedicineManipal University College Malaysia(MUCM)Bukit BaruMelaka 75150Malaysia Centre for Neuroscience Research(NeuRon) Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Department of Medical Education Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Department of Biochemistry and Molecular Medicine Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia School of Medicine International Medical UniversityBukit JalilKuala Lumpur 57000Malaysia Department of Pharmacology and Bioinformatics Volgograd State Medical UniversityVolgograd 400131Russia

AIM:To investigate the stability of the seven housekeeping genes:beta-actin(ActB),glyceraldehyde-3-phosphate dehydrogenase(GAPDH),18s ribosomal unit 5(18s),cyclophilin A(CycA),hypoxanthine-guanine phosphoribosyl transferase(HPRT),ribosomal protein large P0(36B4)and terminal uridylyl transferase 1(U6)in the diabetic retinal tissue of rat ***:The expression of these seven genes in rat retinal tissues was determined using real-time quantitative reverse transcription polymerase chain reaction(RT-qPCR)in two groups;normal control rats and streptozotocininduced diabetic *** stability analysis of gene expression was investigated using geNorm,NormFinder,BestKeeper,and comparative delta-Ct(ΔCt)***:The 36B4 gene was stably expressed in the retinal tissues of normal control animals;however,it was less stable in diabetic *** 18s gene was expressed consistently in both normal control and diabetic rats’retinal *** this gene was the best reference for data normalisation in RT-qPCR studies that used the retinal tissue of streptozotocin-induced diabetic ***,there was no ideal gene stably expressed for use in all experimental ***:Identifying relevant genes is a need for achieving RT-qPCR validity and reliability and must be appropriately achieved based on a specific experimental setting.

关键词： housekeeping genes stability real-time reverse transcription polymerase chain reaction retinal tissue streptozotocin-induced diabetic rats

Effect of inlet elbow on rotation stall in waterjet ppropulsionpump

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Fundamental Research 2024年第4期4卷 898-906页

作者： Wei Li Shuo Li Leilei Ji Enda Li Weidong Shi Ramesh agarwal Muhammad Awais National Research Center of Pumps Jiangsu UniversityZhenjiang 212013China Institute of Fluid Engineering Equipment Technology Jiangsu UniversityZhenjiang 212009China College of Mechanical Engineering Nantong UniversityNantong 226019China departmentof Mechanical Engineering&Materials Science Washington University in StLouisSt.LouisMO6330US.

To study the influence of an elbow inlet on the rotating stall characteristics of a waterjet propulsion pump(WJPP),a three-dimensional internal flow field in a WJPP under a straight-pipe inlet and elbow inlet is numerically *** comparing the hydraulic performance of WJPP under the two inlet conditions,the internal relationship between the inlet mode and the flow pattern in the pump is *** on unsteady pressure fluctuation characteristics and wavelet analysis,the influence of the inlet mode on the rotating stall is revealed,and the stall transient propagation characteristics under critical stall conditions are *** disturbance effects of the inlet channel geometry disappear under low flow rate conditions,the main disturbance is induced by the highspeed countercurrent,and the flow pattern under the elbow inlet is better than that under the straight-pipe *** the straight-pipe inlet,the single-stall nucleus in the WJPP temporarily experiences a low-frequency and high-amplitude disturbance,which subsequently transforms into a mode of multi-stall nuclei with high-frequency circumferential *** the elbow inlet,the rotating stall always maintains a mode of high-amplitude and low-frequency disturbance,which represents the transient characteristics of a single stall core propagating in the circumferential direction inside the *** results of this study have a reference value for structural design optimization in a WJPP.

关键词： Waterjet propulsion pump Inlet condition Rotation stall Flow structure Pressurefluctuation

Advancements in nanotechnology for the delivery of phytochemicals

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Journal of Integrative Medicine 2024年第4期22卷 385-398页

作者： Divya Chauhan Pavan K.Yadav Nazneen Sultana Arun agarwal Saurabh Verma Manish K.Chourasia Jiaur R.Gayen Division of Pharmaceutics and Pharmacokinetics Central Drug Research InstituteCouncil of Scientific and Industrial ResearchLucknow 226031Uttar PradeshIndia Academy of Scientific and Innovative Research Ghaziabad 201002Uttar PradeshIndia

Phytosomes(phytophospholipid complex) are dosage forms that have recently been introduced to increase the stability and therapeutic effect of herbal medicine. Currently, bioactive herbs and the phytochemicals they contain are considered to be the best remedies for chronic diseases. One promising approach to increase the efficacy of plant-based therapies is to improve the stability and bioavailability of their bio-active ingredients. Phytosomes employ phospholipids as their active ingredients, and use their amphiphilic properties to solubilize and protect herbal extracts. The unique properties of phospholipids in drug delivery and their use in herbal medicines to improve bioavailability results in significantly enhanced health benefits. The introduction of phytosome nanotechnology can alter and revolutionize the current state of drug delivery. The goal of this review is to explain the application of phytosomes, their future prospects in drug delivery, and their advantages over conventional formulations.

关键词： Phytochemical Bioavailability Drug delivery system Phytosome Plant extracts

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***: SAR Deforestation Classification of Amazon Forest for Land Use Land Cover Application

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Journal of Computer and Communications 2024年第3期12卷 68-83页

作者： Priyanka Darbari Ankush agarwal Manoj Kumar Computer Engineering and Application GLA University Mathura India Department of Information Technology GGV Bilaspur India

The process of turning forest area into land is known as deforestation or forest degradation. Reforestation as a fraction of deforestation is extremely low. For improved qualitative and quantitative classification, we used Sentinel-1 dataset of State of Para, Brazil to precisely and closely monitor deforestation between June 2019 and June 2023. This research aimed to find out suitable model for classification called Satellite Imaging analysis by Transpose deep neural transformation network (SIT-net) using mathematical model based on Band math approach to classify deforestation applying transpose deep neural network. The main advantage of proposed model is easy to handle SAR images. The study concludes that SAR satellite gives high-resolution images to improve deforestation monitoring and proposed model takes less computational time compared to other techniques.

关键词： Brazilian Amazon Sentinel-1 Band Math Transpose CNN Transformation Network

Deep Learning-Based Speech Emotion Recognition: Leveraging Diverse Datasets and Augmentation Techniques for Robust Modeling

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Journal of Harbin Institute of Technology(New series) 2024年

作者： Ayush Porwal Praveen Kumar Tyagi Ajay Sharma Dheeraj Kumar agarwal Department of Electronics and Instrumentation Engineering， Shri G.S.Institute of Technology and Science Department of Electronics and Communication Engineering， Maulana Azad National Institute of Technology School of Computing Science and Engineering， VIT Bhopal University

In recent years， Speech Emotion Recognition (SER) has developed into an essential instrument for interpreting human emotions from auditory data. The proposed research focused on the development of a SER system employing deep learning and multiple datasets containing samples of emotive speech. The primary objective of this research endeavor is to investigate the utilization of Convolutional Neural Networks (CNNs) in the process of sound feature extraction. Stretching， pitch manipulation， and noise injection are a few of the techniques utilized in this study to improve the data quality. The investigation includes coverage of these methods. Feature extraction methods including Zero Crossing Rate， Chroma＿stft， MFCC， RMS， and MelSpectogram are used to train a model. By using these techniques， audio signals can be transformed into recognized features that can be utilized to train the model. Ultimately， the study will produce a thorough evaluation of the model’s performance. When this method was applied， the model achieved an impressive accuracy of 94.57% on the test dataset. Proposed work also validated on EMO-BD and IEMOCAP dataset. These consist of further data augmentation， feature engineering， and hyperparameter optimization. By following these development paths， SER systems will be able to be implemented in real-world scenarios with greater accuracy and resilience.

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Tuberculosis in kidney transplant candidates and recipients

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World Journal of Transplantation 2024年第3期14卷 59-69页

作者： Pallavi Prasad Sourabh Sharma Subashri Mohanasundaram Anupam agarwal Himanshu Verma Department of Nephrology Vardhman Mahavir Medical College and Safdarjung HospitalNew Delhi 110029DelhiIndia Department of Nephrology Prashanth HospitalChennai 600042Tamil NāduIndia

Tuberculosis(TB)is the leading cause of infectious mortality and morbidity in the world,second only to coronavirus disease *** with chronic kidney disease and kidney transplant recipients are at a higher risk of developing TB than the general *** TB is difficult to diagnose in this population due to close *** transplant candidates should be screened for latent TB infection and given TB *** who develop active TB pre-or post-trans-plantation should receive multidrug combination therapy of antitubercular therapy for the recommended duration with optimal dose modification as per glomerular filtration rate.

关键词： Tuberculosis Latent Antitubercular therapy Kidney transplantation Donor Interferon-gamma release assays Tuberculin Rifampicin Isoniazid