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Non-pulmonary involvement in COVID-19:A systemic disease rather than a pure respiratory infection

World Journal of Clinical Cases 2023年第3期11卷 493-505页

作者： Mohamed El-Kassas Mohamed alboraie Mohamed Elbadry Reem El Sheemy Mohamed Abdellah Shimaa Afify Ahmad Madkour Mariam Zaghloul Abeer Awad Mohamed-Naguib Wifi amira al balakosy Mohamed Eltabbakh Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11731Egypt Department of Internal Medicine Al-Azhar UniversityCairo 11884Egypt Department of Tropical Medicine Minia Faculty of MedicineMinia UniversityMinia 61511Egypt Department of Gastroenterology National Hepatology and Tropical Medicine Research InstituteCairo 11451Egypt Department of Hepatology Gastroenterology and Infectious DiseasesFaculty of MedicineKafrelsheikh UniversityKafrelsheikh 33511Egypt Department of Internal Medicine Hepatogastroenterology UnitKasr Al-Ainy School of MedicineCairo 11451Egypt Department of Tropical Medicine Ain Shams UniversityCairo 11451Egypt

During the early phase of the coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),diagnosis was difficult due to the diversity in symptoms and imaging findings and the variability of disease *** manifestations are reportedly the main clinical presentations of COVID-19 *** are working hard on a myriad of clinical,epidemiological,and biological aspects to better understand SARS-CoV-2 infection,aiming to mitigate the ongoing *** reports have documented the involvement of various body systems and organs apart from the respiratory tract including the gastrointestinal,liver,immune system,renal,and neurological *** involvement will result in diverse presentations related to effects on these *** presentations such as coagulation defects and cutaneous manifestation may also *** with specific comorbidities including obesity,diabetes,and hypertension have increased morbidity and mortality risks with COVID-19.

关键词： COVID-19 Non-pulmonary Extrapulmonary Clinical manifestations Systemic disease

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Liver transplantation during global COVID-19 pandemic

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World Journal of Clinical Cases 2021年第23期9卷 6608-6623页

作者： Mostafa alfishawy Nso Nso Mahmoud Nassar Jonathan Ariyaratnam Sakil Bhuiyan Raheel S Siddiqui Matthew Li Howard Chung amira al balakosy Ahmed alqassieh Tibor Fülöp Vincent Rizzo Ahmed Daoud Karim M Soliman Infectious Diseases Infectious Diseases Consultants and Academic Researchers of Egypt IDCARECairo 0000Egypt Department of Medicine Icahn School of Medicine at Mount Sinai(NYC Health and Hospitals:Queens)New YorkNY 11373United States Clinical pharmacy department Icahn School of Medicine at Mount Sinai(NYC Health and Hospitals:Queens)New YorkNY 11373United States Tropical Medicine Department Ain Shams UniversityCairo 11517Egypt Department of Surgery Medical University of South CarolinaCharlestonSC 29425United States Department of Medicine Medical University of South CarolinaCharlestonSC 29425United States Department of Medicine Kasr Alainy Medical SchoolCairo UniversityCairo 11562Egypt

The coronavirus disease 2019(COVID-19)caused by severe acute respiratory disease respiratory syndrome coronavirus-2 has significantly impacted the health care systems *** transplantation(LT)has faced an unequivocal challenge during this unprecedented *** targeted review aims to cover most of the clinical issues,challenges and concerns about LT during the COVID-19 pandemic and discuss the most updated literature on this rapidly emerging subject.

关键词： COVID-19 Calcineurin inhibitors Cytokine Distributive justice End-stage liver disease Immunosuppression Liver transplantation Mortality

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