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Different positive end expiratory pressure and tidal volume controls on lung protection and inflammatory factors during surgical anesthesia

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World Journal of Clinical Cases 2022年第33期10卷 12146-12155页

作者： Yu Wang Yi Yang Ding-Mu Wang Jie Li Quan-Tang Bao Bei-Bei Wang Shu-Jun Zhu Lu zou Department of Anesthesia Xinghua City People's HospitalXinghua 225700Jiangsu ProvinceChina Department of Anesthesiology Suzhou High-Tech Zone People's HospitalSuzhou 215011Jiangsu ProvinceChina Naval Medical Center Naval Medical UniversityPLAShanghai 200433China Department of Anesthesiology Changzhou Hospital of Traditional Chinese MedicineChangzhou 213000Jiangsu ProvinceChina

BACKGROUND Mechanical ventilation can lead to the severe impairment of the metabolic pathway of alveolar surfactants,inactivating alveolar surfactants and significantly reducing lung-chest *** cardiopulmonary function of elderly patients usually reduced to a certain extent,and there are lung complications after surgical anesthesia,just like lung barotrauma caused by mechanical ventilation,atelectasis and postoperative *** To investigate the effects of different positive end expiratory pressures(PEEPs)and tidal volumes(VTs)on respiratory function,the degree of the inflammatory response and hemodynamic indexes in patients undergoing surgery under general *** A total of 120 patients undergoing surgery for gastric or colon cancer under general anesthesia in Xinghua People's Hospital from January 2017 to January 2021 were randomly divided into Group A and Group B,with 60 cases in each *** ventilation mode in Group A was VT(6.0 mL/kg)+PEEP(5.0 cmH_(2)O),while that in Group B was VT(6.0 mL/kg)+PEEP(8.0 cmH_(2)O).Blood gas parameters,respiratory mechanical parameters,inflammatory response indicators,hemodynamic indicators and related complications were compared between the two *** There were no significant differences in PaCO_(2),PaO_(2),oxygen or the examined indexes at T0 between group A and group B(P>0.05).The measured PaO_(2) value of patients in group A at T3 was higher than that in group B,and the difference was significant(P0.05).The measured P_(peak) value of patients in group A at T1 was higher than that in group B,and the difference was significant(P<0.05).The measured Cdyn value at T1 and T2 was greater than that in group B(P<0.05).Before surgery,there were no significant differences in tumor necrosis factor-α(TNF-α),interleukin(IL)-6 or IL-

关键词： General anesthesia Positive end expiratory pressure Tidal volume Respiratory function Inflammatory reactions Hemodynamics

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Adenosine Monophosphate-Activated Protein Kinase,Oxidative Stress,and Diabetic Endothelial Dysfunction

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Cardiology Discovery 2021年第1期1卷 44-57页

作者： Ming-Hui zou Shengnan Wu Center for Molecular and Translational Medicine Georgia State UniversityAtlantaGeorgia 30303USA

Endothelial dysfunction characterized by impaired endothelium-dependent vaso-relaxation is one of the earliest detectable pathological events in smoking,diabetes,and many cardiovascular diseases including hypertension,*** data from human and animals demonstrate that the endothelial dysfunction associated with diabetes is due to the local formation of oxidants and free ***,the mechanisms by which diabetes instigates oxidative stress,and those by which oxidative stress perpetuates endothelial dysfunction are the subjects of intensive research in the last 3 *** studies from us and others have demonstrated that adenosine monophosphate-activated protein kinase(AMPK),a well-characterized energy sensor and modulator,serves as a highly efficient sensor as AMPK can be activated by very low levels of reactive oxygen species(ROS)and reactive nitrogen species(RNS)generated by physiological,pharmacological,and pathologic stimuli(redox sensor).Interestingly,oxidants-activated AMPK feedback lowers the levels of ROS by either suppressing ROS/RNS from reduced nicotinamide adenine dinucleotide phosphate(NADPH)oxidase and mitochondria or by increasing the levels of antioxidant enzymes(redox modulator).Further,our studies demonstrate that AMPK’s functions as a redox sensor and modulator are vital to maintain endothelial cell function under physiological ***,we discover that under chronic oxidative stress or large influx of ROS,AMPK is particularly susceptible to inhibition by *** conclude that oxidative inactivation of AMPK in diabetes perpetuates oxidative stress and accelerates atherosclerosis in diabetes.

关键词： Adenosine monophosphate-activated protein kinase Atherosclerosis Endothelial cell Nitric oxide Oxidative stress

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Synthesis Optimization of SSZ-13 Zeolite Membranes by Dual Templates for N_(2)/NO_(2) Separation

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Chemical Research in Chinese Universities 2022年第1期38卷 250-256页

作者： LI Jun RONG Huazhen CHEN Cong LI Ziyi ZUO Jiayu WANG Wenjian LIU Xinjian GUAN Yixing YANG Xiong LIU Yingshu zou Xiaoqin ZHU Guangshan School of Energy and Environmental Engineering University of Science and Technology BeijingBeijing 100083P.R.China Faculty of Chemistry Northeast Normal UniversityChangchun 130024P.R.China Science and Technology on Reactor System Design Technology Laboratory Nuclear Power Institute of ChinaChengdu 610213P.R.China

High-silica SSZ-13 zeolite membranes are promising in industrial separations of light gases and continuous membranes are highly demanded for better separation performances. Herein, pure-phase, continuous and thin SSZ-13 zeolite membranes were synthesized using dual templates of N,N,N-trimethtyl-1-adamantammonium hydroxide(TMAdaOH) and tetraethylammonium hydroxide(TEAOH). Systematical investigations of TMAdaOH/TEAOH ratios and their concentrations show that TMAdaOH acts as the main structure-directing agent in the formation of the SSZ-13 zeolite. TMAdaOH cooperatively plays with TEAOH in promoting the SSZ-13 crystal intergrowth to form a continuous polycrystalline membrane. Additionally, appropriate introduction of TEAOH is able to adjust the membrane thickness to the crystal-comparable size of ca. 2.0 μm. The SSZ-13 membranes are further applied for N2/NO2separation, which is firstly reported on zeolite membranes. The gas permeation results show that the SSZ-13 membrane synthesized by the dual-template approach exhibits selective separation of N2 over NO2 with N2/NO2 separation factor of 7.6 and N2 permeance of 1.66×10-8 mol·m-2·s-1·Pa-1.

关键词： Zeolite membrane Dual template SSZ-13 Gas separation Nitrogen dioxide

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Sensitivity of solar greenhouse envelopes to the thermal disfigurements and optimal selection of the thermal insulation quilt

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International Journal of Agricultural and Biological Engineering 2021年第5期14卷 50-55页

作者： Yachen Sun Yao Zhang Chenmeng Zhu Shaonan Xu Bowen Liu Yanfei Cao Changji Zhou Yaqi Zhou Zhirong zou Encai Bao College of Architecture and Urban Planning Tongji UniversityShanghai 200092China Institute of Agricultural Facilities and Equipment Jiangsu Academy of Agricultural ScienceKey Laboratory of Protected Agriculture Engineering in the Middle and Lower Reaches of Yangtze RiverMinistry of Agriculture and Rural AffairsNanjing 210014China School of Engineering Anhui Agricultural UniversityHefei 230036China Department of Management City University of Hong KongTat Chee Avenue KowloonHong Kong 999077China Qinghai College of animal husbandry and veterinary technology Xining 812100China School of Ocean and Earth Science Tongji UniversityShanghai 200092China Key Laboratory of Protected Horticultural Engineering in Northwest Ministry of Agriculture and Rural AffairsDepartment of HorticultureNorthwest A&F UniversityYangling 712100ShaanxiChina Academy of Agricultural Planning and Engineering Ministry of Agriculture and Rural AffairsBeijing 100125China School of Karst Science Guizhou Normal UniversityGuiyang 550001China

The objectives of the present work are focused on exploration of the reasons for temperature difference in different envelopes,the sensitivity of envelopes of solar greenhouse to thermal disfigurements and optimal selection of the thermal insulation *** analysis and derivation are conducted according to the experimental results of surface temperature,convective heat transfer,and heat flux density in different envelopes which with thermal disfigurements of solar greenhouse using heat transfer *** results revealed that the difference of intrinsic thermal conductivity and thickness of the envelopes leads to difference in the thermal flux and thus in the surface temperature of different *** with the front roof and back roof,the wall is more sensitive to thermal *** to the influence of thermal disfigurements on solar greenhouse temperature,the allowable thermal disfigurements area fraction of front roof and back roof are *** on the analysis of heat transfer theory and test results,the work given the expression of the thickness and thermal conductivity of thermal insulation quilt under different outdoor minimum temperatures for optimal selection of thermal insulation quilt based on comprehensive considering factors of the solar greenhouse structure,crop demand,outdoor minimum temperature,and insulation quilt *** results of this work give technical criterion for whether the envelopes with thermal disfigurements needs to be repaired or replaced,and it also provides theoretical and technical support for design the solar greenhouse as well as methodological guidance for the optimal selection of the thermal insulation quilt.

关键词： solar greenhouse thermal disfigurements optimal selection thermal insulation quilt

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Physiological Effects of MgO and ZnO Nanoparticles on the Citrus maxima

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Journal of Wuhan University of Technology(Materials Science) 2019年第1期34卷 243-253页

作者： XIAO Lian WANG Shouxia LI Junli School of Chemistry Chemical Engineering and Life Sciences Wuhan University of Technology

Toxicity of MgO and ZnO nanoparticles at concentrations of 250, 500 or 1 000 mg/L for Citrus maxima seedlings was investigated to evaluate the potentiality of their use as nano-fertilizers. Uptake and translocation of metal oxide nanoparticles and lipid peroxidation were measured and compared with those of plants exposed to the highest equivalent concentrations of Mg^(2+) and Zn^(2+). MgO nanoparticles were translocated from roots to shoots, while translocation of ZnO nanoparticles was low. Exposure to Mg^(2+) and MgO at all concentrations entailed severe toxicity and strong oxidative stress. ZnO nanoparticles showed only mild toxicity, while Zn^(2+) caused leaf vein chlorosis and strong oxidative stress to plant shoots. In conclusion, the toxicity of MgO nanoparticles to the plant resulted from the dissolved Mg^(2+) concentration, while that of ZnO nanoparticles was not correlated with the dissolved Zn^(2+) concentration. Our findings are significant for development and application of MgO and ZnO nanoparticles as nano-fertilizers in agriculture.

关键词： MgO and ZnO nanoparticles Citrus maxima translocation lipid peroxidation oxidative stress

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Pseudoileus caused by primary visceral myopathy in a Han Chinese patient with a rare MYH11 mutation:A case report

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World Journal of Clinical Cases 2022年第34期10卷 12623-12630页

作者： Na Li Yi-Ming Song Xian-Da Zhang Xue-Song Zhao Xiang-Yi He Li-Fen Yu Duo-Wu zou Department of Geriatrics Qinghai Provincial People’s HospitalXining 810007Qinghai ProvinceChina Department of Gastroenterology Fenghua District People’s HospitalNingbo 315000Zhejiang ProvinceChina Medical College Shanghai Jiao Tong University School of MedicineShanghai 200025China Department of Radiology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Gastroenterology Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

BACKGROUND Chronic intestinal pseudo-obstruction(CIPO)is a syndrome of intestinal motor dysfunction caused by intestinal nerve,muscle,and/or Cajal stromal cell *** is a serious category of gastrointestinal dynamic dysfunction,which can eventually lead to the death of patients with intestinal *** to considerable phenotypic heterogeneity,the estimated incidence of CIPO is 1/476190 and 1/416666 in men and women,*** to the etiology,CIPO can be divided into idiopathic and secondary,of which the latter is the most common,often secondary to tumor,virus infection,connective tissue disease,neurological diseases,and endocrine *** CIPO in the intestinal tract is divided into visceral myopathy,neuropathy,and stromal cell lesions according to the *** is usually not recommended for CIPO,because it often does not benefit patients with CIPO,and postoperative intestinal obstruction is likely to occur,which may even worsen the *** SUMMARY Here,we describe the case of a 43-year-old male Han Chinese patient with a 15-year history of recurrent abdominal distention with no clear *** results of physical,biochemical,and other relevant examinations showed no clear ***-enhanced computed tomography(CT)indicated a large duodenum,clear expansion of the intestinal lumen,and *** exome sequencing(WES)of the patient and his mother confirmed the diagnosis of primary familial visceral myopathy type 2 chronic pseudoileus with a rare heterozygous gene mutation in *** is the second reported case of CIPO with a heterozygous MYH11[NM_001040113.1:c.5819delC(***1940Hisfs*91)]*** This case report indicates that physicians can perform routine clinical examinations,CT,and WES to achieve a diagnosis and treatment of CIPO in early disease stages.

关键词： Pseudoileus Heterozygous MHY11 gene mutation Whole exome sequencing Contrastenhanced computed tomography Case report

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In vitro corrosion resistance and antibacterial performance of noveltin dioxide-doped calcium phosphate coating on degradable Mg-1Li-1Ca alloy

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Journal of Materials Science & Technology 2019年第3期35卷 254-265页

作者： Lan-Yue Cui Guang-Bin Wei Zhuang-Zhuang Han Rong-Chang Zeng Lei Wang Yu-Hong zou Shuo-Qi Li Dao-Kui Xu Shao-Kang Guan College of Materials Science and Engineering Shandong University of Science and Technology College of Chemical and Environmental Engineering Shandong University of Science and Technology CAS Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal Research Chinese Academy of Sciences School of Materials Science and Engineering Zhengzhou University

A SnO_2-doped calcium phosphate(Ca-P-Sn) coating was constructed on Mg-1 Li-1 Ca alloy by a hydrothermal process. The fabricated functional coatings were investigated using scanning electron microscopy(SEM), X-ray diffraction(XRD) and Fourier transform infrared spectroscopy(FT-IR). A triple-layered structure, which is composed of Ca_3(PO_4)_2,(Ca, Mg)_3(PO_4)_2, SnO_2, and MgHPO_4·3 H_2O, is evident and leads to the formation of Ca_(10)(PO_4)_6(OH)_2 in Hank's solution. Electrochemical measurements, hydrogen evolution tests and plating counts reveal that the corrosion resistance and antibacterial activity were improved through the coating treatment. The embedded SnO_2 nanoparticles enhanced crystallisation of the *** formation and degradation mechanisms of the coating were discussed.

关键词： Magnesium alloys Coatings Corrosion Biomedical materials

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Efficient random saliency map detection

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Science China(Information Sciences) 2011年第6期54卷 1207-1217页

作者： HUANG ZhiYong, HE FaZhi , CAI XianTao, zou ZhengQin, LIU Jing, LIANG MingMing & CHEN XiaoComputer School, Wuhan University, Wuhan 430074, China 1. Computer School Wuhan University Wuhan 430074 China

Most image retargeting algorithms rely heavily on valid saliency map detection to proceed. However, the inefficiency of high quality saliency map detection severely restricts the application of these image retargeting methods. In this paper, we propose a random algorithm for efficient context-aware saliency map detection. Our method is a multiple level saliency map detection algorithm that integrates multiple level coarse saliency maps into the resulting saliency map and selectively updates unreliable regions of the saliency map to refine detection results. Because of the randomized search, our method requires very little additional memory beyond that for the input image and result map, and does not need to build auxiliary data structures to accelerate the saliency map detection. We have implemented our algorithm on a GPU and demonstrated the performance for a variety of images and video sequences, compared with state-of-the-art image processing.

关键词： saliency map detection image retargeting random algorithm

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Tunable flexible artificial synapses:a new path toward a wearable electronic system

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npj Flexible Electronics 2018年第1期2卷 160-168页

作者： Kunlong Yang Sijian Yuan Yuxiang Huan Jiao Wang Li Tu Jiawei Xu Zhuo zou Yiqiang Zhan Lirong Zheng Fernando Seoane School of Engineering Sciences in Chemistry Biotechnology and HealthKTH Royal Institution of TechnologyStockholmSweden State Key Laboratory of ASIC and System SISTFudan UniversityShanghaiChina Department for Clinical Science Intervention and TechnologyKarolinska InstitutetStockholmSweden Department of Biomedical Engineering Karolinska University HospitalStockholmSweden Swedish School of Textiles University of BoråsBoråsSweden

The flexible electronics has been deemed to be a promising approach to the wearable electronic ***,the mismatching between the existing flexible deices and the conventional computing paradigm results an impasse in this *** this work,a new way to access to this goal is proposed by combining flexible devices and the neuromorphic architecture *** achieve that,a high-performance flexible artificial synapse is created based on a carefully designed and optimized memristive *** device exhibits high-performance which has near-linear non-volatile resistance change under 10,000 identical pulse signals within the 515%dynamic range,and has the energy consumption as low as 45 fJ per *** also displays multiple synaptic plasticity features,which demonstrates its potential for real-time online ***,the adaptability by virtue of its threeterminal structure specifically contributes its improved uniformity,repeatability,and reduced power *** work offers a very viable solution for the future wearable computing.

关键词： artificial wear electronic

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Recent Advances in Electrochemical-Based Silicon Production Technologies with Reduced Carbon Emission

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Research 2024年第1期2023卷 209-236页

作者： Feng Tian Zhongya Pang Shen Hu Xueqiang Zhang Fei Wang Wei Nie Xuewen Xia Guangshi Li Hsien-Yi Hsu Qian Xu Xingli zou Li Ji Xionggang Lu State Key Laboratory of Advanced Special Steel&Shanghai Key Laboratory of Advanced Ferrometallurgy&School of Materials Science and Engineering Shanghai University99#Shangda RoadShanghai 200444China Center for Hydrogen Metallurgy Technology Shanghai UniversityShanghai 200444China State Key Laboratory of ASIC and System School of MicroelectronicsFudan University220#Handan RoadShanghai 200433China School of Energy and Environment Department of Materials Science and EngineeringCity University of Hong KongKowloon TongHong KongChina

Sustainable and low-carbon-emission silicon production is currently one of the main focuses for the metallurgical and materials science ***,considered a promising strategy,has been explored to produce silicon due to prominent advantages:(a)high electricity utilization efficiency;(b)low-cost silica as a raw material;and(c)tunable morphologies and structures,including films,nanowires,and *** review begins with a summary of early research on the extraction of silicon by *** has been placed on the electro-deoxidation and dissolution–electrodeposition of silica in chloride molten salts since the 21st century,including the basic reaction mechanisms,the fabrication of photoactive Si films for solar cells,the design and production of nanoSi and various silicon components for energy conversion,as well as storage ***,the feasibility of silicon electrodeposition in room-temperature ionic liquids and its unique opportunities are *** this basis,the challenges and future research directions for silicon electrochemical production strategies are proposed and discussed,which are essential to achieve large-scale sustainable production of silicon by electrochemistry.

关键词： directions electrodeposition electricity

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