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Effects of the hydro-ethanolic extract of Marrubium vulgare in female rats

Asian Pacific Journal of Tropical Medicine 2017年第2期10卷 154-158页

作者： Rim Aouni Mossadok Ben Attia Mohamed Habib Jaafoura amina bibi-Derbel Mustapha Haouari Faculty of Sciences of Bizerte Department of life Sciences7021 JarzounaUniversity of Carthage INNTA SURVEN Research Laboratory(Monitoring and nutritional epidemiology in Tunisia) Laboratoire Biomonitoring of the Environment Faculty of Sciences of Bizerte.7021 JarzounaUniversity of Carthage Orthopedic InstituteMohamed Kassab Laboratory of Cyto-Morphology and Anatomy Pathologic National Institute of Nutrition and Food technology Clinical laboratory of biochemistry Ecole Superior of Science and Technology of Health of Tunis University of Tunis El Manar

Objective:To evaluate the effects of ethanol–water(80:20) extract of Marrubium vulgare(***) on the hematological parameters,macroscopic and histological aspects of the uterus and fetus in non-pregnant and pregnant ***:Female rats were divided into 4 equal groups(n = 9),group N(normal rats) and group G(pregnant rats) considered as control groups,group NE(normal rats treated with the ethanol–water(80:20,v/v) extract of ***) and group GE(pregnant rats treated with the extract).The ethanol–water(80:20) plant extract was administered in a single daily dose 1 g/kg at the morning,during 19 *** the 19 day of the experiment,animals were sacrificed,the uterus and fetuses were removed for the morphological and histological studies and the blood was collected in EDTA tubes for the measurement of hematological parameters with the use of an automate ‘HORIBA ABX Micros 60 Hematology Analyzer'.Results:Our results showed,in group NE and GE,a significant decrease on hematological parameters:red blood cells(NE:18.6%;GE:38.4%),hematocrit(NE:13.8%;GE:20.4%),hemoglobin(NE:12.1%;GE:8.3%) and mean corpuscular volume(NE:6.4%;GE:2%) with P more less a ***,the extract of *** caused a significant decrease on the mean implantations of fetuses(82.5%,P<0.001) and their size(47.2%,P< 0.01).As for the macroscopic and histological appearance of uterus,our data showed no change in normal treated *** contrast,the treated pregnant rats showed a severe histological change characterized by the existence of location of stopped ***,it was also found in the uterus of these rat lyses placental and embryo ***:All these results support the hypothesis of an abortifacient effect of ***.

关键词： Vegetal extract Abortificiant effect Hematological parameters Fetuses Uterus Histology

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Skin Lesion Segmentation and Classification Using Conventional and Deep Learning Based Framework

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Computers, Materials & Continua 2022年第5期71卷 2477-2495页

作者： amina bibi Muhamamd Attique Khan Muhammad Younus Javed Usman Tariq Byeong-Gwon Kang Yunyoung Nam Reham R.Mostafa Rasha H.Sakr Department of Computer Science HITEC UniversityTaxilaPakistan College of Computer Engineering and Sciences Prince Sattam Bin Abdulaziz UniversityAl-KhrajSaudi Arabia Department of ICT Convergence Soonchunhyang UniversityAsan31538Korea Information Systems Department Faculty of Computers and Information SciencesMansoura UniversityMansoura35516Egypt Computer Science Department Faculty of Computers and Information SciencesMansoura UniversityMansoura35516Egypt

Background:In medical image analysis,the diagnosis of skin lesions remains a challenging *** lesion is a common type of skin cancer that exists *** is one of the latest technologies used for the diagnosis of skin ***:Many computerized methods have been introduced in the literature to classify skin ***,challenges remain such as imbalanced datasets,low contrast lesions,and the extraction of irrelevant or redundant *** Work:In this study,a new technique is proposed based on the conventional and deep learning *** proposed framework consists of two major tasks:lesion segmentation and *** the lesion segmentation task,contrast is initially improved by the fusion of two filtering techniques and then performed a color transformation to color lesion area color ***,the best channel is selected and the lesion map is computed,which is further converted into a binary form using a thresholding *** the lesion classification task,two pre-trained CNN models were modified and trained using transfer *** features were extracted from both models and fused using canonical correlation *** the fusion process,a few redundant features were also added,lowering classification accuracy.A new technique called maximum entropy score-based selection(MESbS)is proposed as a solution to this *** features selected through this approach are fed into a cubic support vector machine(C-SVM)for the final ***:The experimental process was conducted on two datasets:ISIC 2017 and *** ISIC 2017 dataset was used for the lesion segmentation task,whereas the HAM10000 dataset was used for the classification *** achieved accuracy for both datasets was 95.6% and 96.7%, respectively, which was higher thanthe existing techniques.

关键词： Skin cancer lesion segmentation deep learning features fusion classification

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官僚制度质量和滥用权力对巴基斯坦FDI的影响

官僚制度质量和滥用权力对巴基斯坦FDI的影响

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作者： amina bibi 长安大学

学位级别：硕士

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Synthesis, Biological Evaluation, and SAR Studies of Varyingly Substituted 4-Thioflavonols

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Open Journal of Medicinal Chemistry 2022年第2期12卷 15-25页

作者： Rubina bibi amina Sadiq Ehsan Ullah Mughal Department of Chemistry Government College Women University Sialkot Pakistan Department of Chemistry University of Gujrat Gujrat Pakistan

A series of 4-thioflavonols compounds were synthesized by treating flavonols with lawsons reagent with variable substituent groups at A, B, and AB rings. All the synthesized compounds were checked for antibacterial and antifungal activity. We report that many compounds were found active against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus, bacterial strains and, C. albicans, C. parapsilosisstrains and C. krusei fungal strains. Most of the synthesized 4-thioflavonols compounds were found to show enhanced antimicrobial activity than respective flavonol compounds.

关键词： Flavonols 4-Thioflavonols Flavonoids Lawsons Reagent Antibacterial Activity Antifungal Activity One Pot Synthesis Sulfur Compounds SAR Studies

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