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Advanced maternal age and adverse obstetrical and neonatal outcomes of singleton pregnancies

Gynecology and Obstetrics Clinical Medicine 2022年第4期2卷 175-180页

作者： Mitra Shekari Malihe Shirzadfardjahromi amene ranjbar Vahid Mehrnoush Fatemeh Darsareh Nasibeh Roozbeh Mother and Child Welfare Research Center Hormozgan University of Medical SciencesBandar AbbasIran Fertility and Infertility Research Center Hormozgan University of Medical SciencesBandar AbbasIran Urology Department Northern Ontario School of MedicineThunder BayOntarioCanada

Objective:To assess the impact of advanced maternal age on pregnancy and childbirth outcomes of singleton *** design:We retrospectively assessed singleton pregnant mothers who gave birth at Khaleej-e-Fars Hospital in Bandar Abbas,Iran,from January 2020 to January *** and obstetrical factors include educational level,medical insurance,residency place,access to prenatal care facilities,number of prenatal care visits,smoking status,gestational age,parity,infertility,maternal comorbidities,preeclampsia,eclampsia,preterm birth,low birth weight(LBW),intrauterine growth restriction(IUGR),macrosomia,placenta abnormalities(previa/acreta),placenta abruption,chorioamnionitis,meconium fluid,fetal distress,methods of delivery,rate of cesarean section(CS),perineal lacerations,postpartum hemorrhage,childbirth injury,shoulder dystocia,congenital malformation,neonatal asphyxia,and unfavorable maternal and neonatal outcome were compared between two *** Chi-square test assessed the relationship between categorical factors and maternal age *** influence of advanced maternal age on the risk of unfavorable pregnancy outcomes was evaluated using bivariate and multivariate logistic ***:Of 8354 singleton deliveries,22.2%belonged to advanced-age ***-age mothers had less education than those aged 20–34 years *** hypertension,cardiovascular disease,overt diabetes,and thyroid dysfunction were more prevalent among advanced-age *** with mothers aged 20–34 years,mothers aged 35 years and higher had a significantly higher risk of gestational diabetes(aOR:3.18,95%CI:1.56–6.95),preeclampsia(aOR:2.91,95%CI:1.35–4.72),placenta abnormalities(aOR:1.09,95%CI:0.77–1.94),CS(aOR:3.16,95%CI:1.51–3.87),postpartum hemorrhage(aOR:1.94,95%CI:1.24–2.61),intensive care unit admission(aOR:1.36,95%CI:1.15–1.99),LBW(aOR:1.35,95%CI:0.97–2.96),preterm birth(aOR:2.36,95%CI:1.65–4.83),stillbirth(aOR:1.18,95%CI:1.01–3.16),and neonatal

关键词： Advanced maternal age Pregnancy Childbirth Perinatal outcome Neonatal outcomes

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Does cesarean section prevent adverse neonatal outcomes associated with meconium amniotic fluid?

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Gynecology and Obstetrics Clinical Medicine 2023年第4期3卷 241-244页

作者： amene ranjbar Sepideh Rezaei Ghamsari Elham Taeidi Vahid Mehrnoush Fatemeh Darsareh Fertility and Infertility Research Center Hormozgan University of Medical SciencesBandar AbbasIran Department of Midwifery and Reproductive Health Tehran University of Medical SciencesTehranIran Mother and Child Welfare Research Center Hormozgan University of Medical SciencesBandar AbbasIran Urology Department Northerm Ontario School of MedicineThunder BayOntarioCanada

Background Making decisions regarding the mode of delivery in the cases of meconium amniotic fluid(MAF)presents a challenge for healthcare *** aimed to compare the neonatal outcome of MAF cases delivered via cesarean section(CS)versus those delivered vaginally to determine if CS is a protective factor against the adverse neonatal *** In this retrospective study,we assessed singleton pregnant mothers diagnosed with MAF who gave birth at a tertiary hospital in Bandar Abbas,Iran,between January *** with certain adverse pregnancy conditions were excluded from the *** conditions included:abnormal fetal heart rate and pattern,bloody amniotic fluid,malpresentation,abnormal placentation,chorioamnionitis,intrauterine growth restriction,intrauterine fetal death,obstructed labor,and maternal *** MAF mothers were divided into two groups based on the method of delivery:those who had CS and those who had a normal vaginal delivery(NVD).Demographic factors,obstetrical factors,and neonatal outcomes were compared between the two *** Out of 746 MAF mothers,213(28.5%)underwent CS,while 533(71.4%)had *** were no significant differences between the groups in terms of demographic *** MAF mothers who had CS,66.2%were primiparous,and 33.8%were *** those who had NVD,35.1%were primiparous,and 64.9%were *** first and 5-min Apgar values,rates of asphyxia,neonatal intensive care unit(NICU)admission,and neonatal death were not statistically different between the two delivery *** rate of newborns who breastfed within the first hour did not differ depending on the mode of *** initial resuscitation steps were required more frequently in MAF mothers with NVD than in those with CS(11.1%vs.2.3%),no correlation was found between the mode of delivery and the need for resuscitation using logistic *** Our research findings suggest that there were no sup

关键词： Meconium Amniotic fluid Neonatal outcomes

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Predicting risk of postpartum hemorrhage using machine learning approach:A systematic review

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Gynecology and Obstetrics Clinical Medicine 2023年第3期3卷 170-174页

作者： amene ranjbar Sepideh Rezaei Ghamsari Banafsheh Boujarzadeh Vahid Mehrnoush Fatemeh Darsareh Fertility and Infertility Research Center Hormozgan University of Medical SciencesBandar AbbasIran Department of Midwifery and Reproductive Health Tehran University of Medical SciencesTehranIran Mother and Child Welfare Research Center Hormozgan University of Medical SciencesBandar AbbasIran

Background Postpartum hemorrhage(PPH)could be avoided by identifying high-risk *** objective of this systematic review is to determine PPH predictors using machine learning(ML)*** This strategy included searching for studies from inception through November 2022 through the database included:Cochrane Central Register,PubMed,MEDLINE,EMBASE,ProQuest,Scopus,WOS,IEEE Xplore,and the Google Scholar *** search methodology employed the PICO framework(population,intervention,control,and outcomes).In this study,“P”represents PPH populations,“I”represents the ML approach as intervention,“C”represents the traditional statistical analysis approach as control,and“O”represents prediction and diagnosis *** quality assessment of each included study was performed using the PROBAST *** The initial search strategy resulted in 2048 citations,which were subsequently refined by removing duplicates and irrelevant ***,four studies were deemed eligible for inclusion in the *** these studies,three were classified as having a low risk of bias,while one was considered to have a low to moderate risk of bias.A total of 549 unique variables were identified as candidate predictors from the included *** distinct models were chosen as ML algorithms from the four *** of the four studies employed different metrics,such as the area under the curve,false positive rate,false negative rate,and sensitivity,to report the accuracy of their *** ML models exhibited varying accuracies,with the area under the curve(AUC)ranging from 0.706 to *** weighted predictors were identified as significant factors in PPH risk *** included pre-pregnancy maternal weight,maternal weight at the time of admission,fetal macrosomia,gestational age,level of hematocrit at the time of admission,shock index,frequency of contractions during labor,white blood cell count,pregnancy-induced hypertension,the weight of

关键词： Postpartum hemorrhage Risk factors Machine learning

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Urban-rural differences in the pregnancy-related adverse outcome

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Gynecology and Obstetrics Clinical Medicine 2023年第1期3卷 51-55页

作者： Vahid Mehrnoush amene ranjbar Farzaneh Banihashemi Fatemeh Darsareh Mitra Shekari Malihe Shirzadfardjahromi Mother and Child Welfare Research Center Hormozgan University of Medical SciencesBandar AbbasIran Urology Department Northern Ontario School of MedicineThunder BayOntarioCanada Fertility and Infertility Research Center Hormozgan University of Medical SciencesBandar AbbasIran

Background:Little is known about potential urban-rural differences in adverse pregnancy *** purpose of this study is to look into the urban-rural differences in the trend of adverse maternal and neonatal ***:We retrospectively assessed the pregnancy outcome of singleton pregnant mothers who gave birth at a tertiary hospital in Bandar Abbas,Iran,between January 1st,2020,and January 1st,*** were divided into two groups based on living residency:1)urban groupand 2)rural *** factors,obstetrical factors,maternal comorbidities,and adverse maternal and neonatal outcomeswere extracted from the electronic data of each *** Chi-square testwas used to compare differences between the groups for categorical *** regression models were used to assess the association of adverse pregnancy,childbirth,and neonatal outcome with living ***:Of 8888 mothers that gave birth during the study period,2989(33.6%)lived in rural *** pregnancy was more common in the rural *** mothers had a higher education than rural *** mothers were at higher risk for preterm birth aOR 1.81(CI:1.24-2.99),post-term pregnancy aOR 1.5(CI:1.07-2.78),anemia aOR 2.02(CI:1.07-2.34),low birth weight(LBW)aOR 1.89(CI:1.56-2.11),need for neonatal resuscitation aOR 2.66(CI:1.78-3.14),and neonatal intensive care unit(NICU)admission aOR 1.98(CI:1.34-2.79).On the other hand,the risk of cesarean section was significantly lower compared to urban mothers aOR 0.58(CI:0.34-0.99).Conclusions:Our study discovered that mothers living in rural areas had a higher risk of developing anemia,preterm birth,post-term pregnancies,LBW,need for neonatal resuscitation,and NICU admission,but a lower risk of cesarean section.

关键词： Pregnancy outcome Urban Rural Living residency

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Pregnancy,childbirth and neonatal outcomes associated with adolescent pregnancy

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Gynecology and Obstetrics Clinical Medicine 2023年第2期3卷 100-105页

作者： amene ranjbar Maliheh Shirzadfard Jahromi Banafsheh Boujarzade Nasibeh Roozbeh Vahid Mehrnoush Fatemeh Darsareh Fertility and Infertility Research Center Hormozgan University of Medical SciencesBandar AbbasIran Mother and Child Welfare Research Center Hormozgan University of Medical SciencesBandar AbbasIran Urology Department Northern Ontario School of MedicineThunder BayOntarioCanada

Objective:To assess the obstetric and neonatal outcomes associated with adolescent pregnancy in ***:We retrospectively assessed women who gave birth between January 1st,2020,and January 1st,*** pregnant women were separated into two groups:(1)women aged 19 and younger;(2)women aged 20-34 *** outcome measures include preterm birth,maternal comorbidities,preeclampsia,eclampsia,low birth weight(LBW),intrauterine growth restriction(IUGR),placenta abnormalities,placenta abruption,cho-rioamnionitis,meconium fluid,fetal distress,methods of delivery,rate of cesarean section(CS),perineal lacer-ations,postpartum hemorrhage,childbirth trauma,shoulder dystocia,congenital malformation,and unfavorable maternal and neonatal *** regression models were used to determine the influence of teenage pregnancy on adverse pregnancy and childbirth ***:Of 7033 deliveries,92.4%of women were adults,and 7.6%were *** residing in rural districts were more common than adults(42.3%vs.33.7%).However,access to prenatal facility care was the same as the majority of women had 6-10 prenatal care visits during their *** was no difference in the risk of preeclampsia,placenta abruption,placenta previa,fetal distress,preterm labor,shoulder dystocia,perineal lacerations,childbirth trauma,congenital malformation,postpartum hemorrhage,intensive care unit admission,maternal death,and unfavorable neonatal outcome including stillbirth,neonatal intensive care unit admission,neonatal death in adolescent pregnancies compared to *** had a significantly higher risk of LBW(OR:1.47,95%CI:1.01-2.73),IUGR(OR:1.96,95%CI:1.31-2.45),and meconium fluid(OR:1.74,95%CI:1.41-2.32),however,there was no statistically significant difference after adjusting the confounding *** with adults,adolescents had a significantly lower risk of CS(aRR:0.67,95%CI:0.51-0.77)and a lower risk of gestational diabetes(aRR:0.78,95%CI:0.51-0.95)

关键词： Adolescents Pregnancy Childbirth Perinatal outcome Neonatal outcomes

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Oxidative Diels-Alder reaction of 2,5-dihydroxybenzoic acid with 1,3-cyclopentadiene

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Chinese Chemical Letters 2013年第3期24卷 205-207页

作者： Davood Nematollahi Adel Ghorbani amene Amani Hamid Salehzadeh Hadi Beiginejad Faculty of Chemistry Bu-Ali Sina University

The electrochemical oxidation of 2,5-dihydroxybenzoic acid （1） has been studied in the presence of 1,3- cyclopentadiene （2） as a diene in water/ethanol （40/60, v/v） mixture using cyclic voltammetry and controlled-potential coulometry. A plausible mechanism for the oxidation of 1 in the presence of 2 is presented. Compound 1 was converted into bis-adduct 5 via electrooxidation, Diels-Alder reaction of 2 to anodically generated 3,6-dioxocyclohexa-l,4-dienecarboxylic acid （lox）, decarboxylation reaction, electrooxidation and Diels-Alder reaction. The electrochemical synthesis of 5 was performed in a one- pot reaction, without toxic reagents, at a carbon electrode in a simple cell using an environmentally friendlv method.

关键词： ECCEC pathwayElectrochemical oxidationDiels-Alder reaction1 3-Cyclopentadiene2 5-Dihydroxybenzoic acid

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The concentration and probabilistic risk assessment of potentially toxic elements in fillets of silver pomfret(Pampus argenteus):A global systematic review and meta-analysis

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Journal of Environmental Sciences 2021年第2期33卷 167-180页

作者： Mohammadreza Alipour Mansour Sarafraz Hossein Chavoshi Abotaleb Bay amene Nematollahi Mohsen Sadani Yadolah Fakhri Yasser Vasseghian Amin Mousavi Khaneghah Student Research Committee School of Public Health and SafetyShahid Beheshti University of Medical SciencesTehran***Iran Department of Anatomy Shahid Beheshti University of Medical SciencesTehran***Iran Enuvironmental Health Research Center Golestan University of Medical SciencesGolestan***Iran Department of Food Safety and Hygiene School of HealthFasa University of Medical SciencesFasa***Iran Department of Environmental Health Engineering School of Public Health and SafetyShahid Beheshti Universityof Medical SciencesTehran***Iran Food Health Research Center Hormozgan University of Medical SciencesBandar Abbas***Iran Institute of Research and Development Duy Tan UniversityDa Nang 550000Vietnam Department of Food Science Faculty of Food Engineering University of Campinas(Unicamp)Rua Monteiro Lobato80 Caixa 6121 CampinasSao Paulo13083-862Brazil

The contamination of fish type products such as silver pomfret fish fillets by potentially toxic elements(PTEs)has raised global health *** studies regarding the concentration of PTEs in fillets of silver pomfret fish were retrieved among some international databases such as Scopus,Pub Med and Embase between 1 January 1983 and 10 March *** pooled(mean)concentration of PTEs in fillets of silver pomfret fish was meta-analyzed with the aid of a random-effect model(REM).Also,the non-carcinogenic risk was estimated via calculating the 95 th percentile of the total target hazard quotient(TTHQ).The meta-analysis of 21 articles(containing 25 studies or data reports)indicated that the ranking of PTEs in fillets of silver pomfret fish was Fe(11,414.81μg/kg wet weight,ww)>Zn(6055.72μg/kg ww)>Cr(1825.79μg/kg ww)>Pb(1486.44μg/kg ww)>Se(1053.47μg/kg ww)>Cd(992.50μg/kg ww)>Ni(745.23μg/kg ww)>Cu(669.71μg/kg ww)>total As(408.24μg/kg ww)>Co(87.03μg/kg ww)>methyl Hg(46.58μg/kg ww).The rank order of health risk assessment by country based on the TTHQ for adult consumers was Malaysia(2.500)>Bangladesh(0.886)>Iran(0.144)>China(0.045)>Pakistan(0.020)>India(0.015),while the corresponding values for child consumers was Malaysia(11.790)>Bangladesh(4.146)>Iran(0.675)>China(0.206)>Pakistan(0.096)>India(0.077).The adult consumers in Malaysia and children in Malaysia and Bangladesh were at considerable non-carcinogenic ***,following the recommended control plans in order to reduce the health risk associated with the ingestion of PTEs via consumption of silver pomfret fish fillets is crucial.

关键词： Potentially toxic elements Heavy metals Silver pomfret Pampus argenteus Marine foods Health risk assessment

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Royal-jelly-based apitherapy can attenuate damages to male reproductive parameter following nicotine administration

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Animal Models and Experimental Medicine 2022年第2期5卷 133-140页

作者： Mahsa Nazar-Zadeh Cyrus Jalili amene Nikgoftar Fathi Ali Ghanbari Mitra Bakhtiari Department of Anatomical Sciences Medical SchoolKermanshah University of Medical SciencesKermanshahIran Medical Biology Research Center Kermanshah University of Medical SciencesKermanshahIran Department of Anatomical Sciences Medical SchoolArak University of Medical SciencesArakIran

Background:Nicotine administration can generate severe oxidative stress and lipid *** jelly,with its antioxidant properties,acts as a scavenger of reactive oxygen *** study describes the apitherapy effects of royal jelly on testicular damage following nicotine ***:Forty-eight male BALB/c mice were divided into 8 groups(n=6):saline,3 different doses of royal jelly(100,150,and 200 mg/kg body weight(BW)per day),nicotine(1.5 mg/kg),and 3 different groups of Nic+Roy(1.5 mg/kg of Nic+100,150,and 200 mg/kg BW per day of royal jelly).Nicotine was administrated intraperitoneally,and royal jelly was prescribed orally for 10 consecutive *** levels of hormones(testosterone,luteinizing hormone,and follicle-stimulating hormone),total antioxidant capacity,nitric oxide(NO)status,malondialdehyde levels,sperm DNA fragmentation,sperm parameters,histopathological changes(H&E staining),immunohistochemistry against apoptotic proteins,and gene expression of Bcl-2,p53,Caspase-3,and Nrf2(real-time PCR)were assessed to evaluate the molecular and histological ***:Hormone levels,sperm parameters,and status of antioxidants were decreased significantly(p<.05)following nicotine ***,royal jelly treatment normalized hormonal and antioxidant characteristics,decreased apoptotic gene expression,increased Nfr2 gene expression,and restored histopathological alteration to the physiological status significantly(p<.05).Conclusion:Royal jelly upregulates the antioxidant status,inhibits the mitochondrialdependent apoptosis pathway,and increases the rate of *** therapeutic agent effectively protected the testis against nicotine-associated damages by antioxidant and anti-apoptotic effects.

关键词： antioxidant apitherapy apoptosis damage male nicotine reproduction royal jelly testis

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COVID-19 and congenital heart disease:a case series of nine children

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World Journal of Pediatrics 2021年第1期17卷 71-78页

作者： Elmira Haji Esmaeil Memar Babak Pourakbari Mojtaba Gorgi Meisam Sharifzadeh Ekbatani amene Navaeian Mahmoud Khodabandeh Shima Mahmoudi Setareh Mamishi Pediatrics Center of Excellence Children's Medical CenterTehran University of Medical SciencesTehranIran Pediatric Infectious Disease Research Center Tehran University of Medical ScienceTehranIran Division of Pediatric Intensive Care Unit Pediatrics Center of ExcellenceChildren's Medical CenterTehran University of Medical SciencesTehranIran Department of Infectious Diseases Pediatrics Center of ExcellenceChildren's Medical CenterTehran University of Medical SciencesTehranIran

Background Coronavirus disease 2019(COVID-19)is the current pandemic disease without any vaccine or efficient treat-ment to rescue the *** diseases predispose the patients to a more severe disease and to a higher mortality ***,little evidence exists about COVID-19 outcomes in the pediatric population with congenital heart disease(CHD).Here,we report nine children with COVID-19 and concomitant *** Our study included nine children with COVID-19 and concomitant CHD who were admitted to Children Medical Center Hospital during March and April *** patients were classified based on the final outcome(death),and their clinical sign and symptoms,type of CHD,and drugs administered were *** Among the nine patients,two died and we compared different characteristics,laboratory results and clinical findings of these cases based on the *** deceased patients had severe types of CHD,worse arterial blood gases,severe clinical symptoms,higher mean level of partial thromboplastin time and C-reactive protein,and required more *** The present study showed that the general consideration of mild COVID-19 in children does not include patients with CHD and that it is necessary to pay greater attention to children with CHD to determine guidelines for treatment of COVID-19 in these *** to the scarcity of CHD and COVID-19,we reported only nine ***,further studies are highly required in this regard.

关键词： Congenital heart disease Coronavirus disease 2019 Pediatrics

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A Wireless Sensor Network Solution for Precision Agriculture Based on Zigbee Technology

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Wireless Sensor Network 2012年第1期4卷 25-30页

作者： Manijeh Keshtgari amene Deljoo 不详

The article has been retracted due to the investigation of complaints received against it. The Editorial Board found that substantial portions of the text quite like the one published in other journal. The problem is ... 详细信息

关键词： Wireless Sensor Network Precision Agriculture Grid Topology Zigbee Network

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