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孕妇口服维生素K1改善新生儿维生素K营养状况

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中国公共卫生 2001年第10期17卷 867-868页

作者：张会丰李根山刘兰芬张玉华乔立敏莫桂初 Martin j.Shearer j.lie harvey 河北医科大学第二医院儿科石家庄050000 山西省太原市南城区医院妇产科伦敦圣托马斯医院维生素K研究室

目的　探索早期预防维生素K缺乏性出血的有效途径。方法　通过孕妇口服维生素K1,观察能否改善其新生儿的维生素K营养状况。结果　对照组新生儿骨钙蛋白未羧化率高于维生素K组 (6 6 6 6 %± 18 2 0 %和 13 41%± 11 96 % ,P <0 ,0 0 1)... 详细信息

目的　探索早期预防维生素K缺乏性出血的有效途径。方法　通过孕妇口服维生素K1,观察能否改善其新生儿的维生素K营养状况。结果　对照组新生儿骨钙蛋白未羧化率高于维生素K组 (6 6 6 6 %± 18 2 0 %和 13 41%± 11 96 % ,P <0 ,0 0 1)。对照组新生儿PIVKA -Ⅱ的阳性率为 2 6 45 % ,而维生素K组PIVKA -Ⅱ阳性率降至 0 % (P <0 0 0 1)。结论让孕妇在分娩后期服用维生素K1可使其新生儿的维生素K营养状况得以改善 ,孕妇口服维生素K1是早期预防维生素K缺乏性出血的新途径。

关键词：维生素K缺乏性出血骨钙蛋白未羧化率新生儿孕妇

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Measurements of Fission Products from the Fukushima Daiichi Incident in San Francisco Bay Area Air Filters,Automobile Filters,Rainwater,and Food

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j.urnal of Environmental Protection 2014年第3期5卷 207-221页

作者： A.R.Smith K.j.Thomas E.B.Norman D.L.Hurley B.T.Lo Y.D.Chan P.V.Guillaumon B.G.harvey Nuclear Science Division Lawrence Berkeley National LaboratoryBerkeleyUSA Department of Nuclear Engineering University of CaliforniaBerkeleyUSA Department of Physics University of Sao PauloSao PauloBrazil

A variety of environmental media were analyzed for fallout radionuclides resulting from the Fukushima nuclear accident by the Low Background Facility (LBF) at the Lawrence Berkeley National Laboratory (LBNL) in Berkeley, CA. Monitoring activities in air and rainwater began soon after the onset of the March 11, 2011 tsunami and are reported here through the end of 2012. Observed fallout isotopes include 131I, 132I, 132Te, 134Cs, 136Cs, and 137Cs. Isotopes were measured on environmental air filters, automobile filters, and in rainwater. An additional analysis of rainwater in search of 90Sr is also presented. Last, a series of food measurements conducted in September of 2013 are included due to extended media concerns of 134,137Cs in fish. Similar measurements of fallout from the Chernobyl disaster at LBNL, previously unpublished publicly, are also presented here as a comparison with the Fukushima incident. All measurements presented also include natural radionuclides found in the environment to provide a basis for comparison.

关键词： Fukushima Daiichi Nuclear Power Plant Fukushima Fallout Air Monitoring Rainwater Automobile Filters Chernobyl

FLT和FDG-PET/CT显像监测食管腺癌新辅助放化疗疗效与组织病理学反应间关系的初步研究

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中华核医学与分子影像杂志 2018年第8期38卷 583-584页

作者：唐军 Victor H.Gerbaudo j.seph H.Killoran Chun K.Kim j.son L.Hornick j.nathan A.Nowak Peter C.Enzinger harvey j.Mamon 上海交通大学医学院附属苏州九龙医院核医学科 Division of Nuclear Medicine and Molecular Imaging Department of Radiology Brigham and Women's HospitalHarvard Medical School Boston

目的该前瞻性初步研究的目的是比较脱氧胸腺嘧啶核苷（FLT）-PET/CT显像与脱氧葡萄糖（FDG）-PET/CT显像相比在早期判断食管癌新辅助放化疗疗效上的潜能。方法 5例活组织检查证实食管腺癌的患者在微创食管切除术前行新辅助放化疗。根据... 详细信息

目的该前瞻性初步研究的目的是比较脱氧胸腺嘧啶核苷（FLT）-PET/CT显像与脱氧葡萄糖（FDG）-PET/CT显像相比在早期判断食管癌新辅助放化疗疗效上的潜能。方法 5例活组织检查证实食管腺癌的患者在微创食管切除术前行新辅助放化疗。根据放化疗后病灶组织学检测结果,使用Mandard等的分类标准把患者分成病理学有效组和无效组。所有患者在间隔48 h内行FLT-PET/CT显像和FDG-PET/CT显像,显像时间为注药后1 h。以上显像共做3次:（1）新辅助放化疗前;（2）放化疗中;（3）放化疗后。基于显像结果的疗效判断用治疗前后FLT-PET和FDG-PET显像的最大标准摄取值(SUV;)变化（ASUV）来表示。术后分析PET显像结果和病理结果间的关系。结果治疗前所有肿瘤病灶均能摄取FDG和FLT,但FLT摄取低于FDG摄取。新辅助放化疗后,病理有效组（n=3）和无效组（n=2）均可见FDG和FLT摄取降低。放化疗中显像结果发现,病理有效组平均肿瘤FLT摄取的降低（ASUV=-55%）与无效组FLT摄取的降低（△SUV=-29%）间差异有统计学意义（P=0.007）,而FDG摄取降低间的差异无统计学意义（病理有效组平均△SUV=-39%,无效组△SUV=-31%;P=0.74）。放化疗后显像结果发现,病理有效组肿瘤FLT摄取的降低ASUV=-62%,无效组△SUV=-57%,两者间差异无统计学意义（P=0.54）,而FDG摄取降低间的差异接近有统计学意义（有效组△SUV=-74%,无效组△SUV=-52%;P=0.06）。结论该前瞻性初步研究结果发现,肿瘤早期FLT摄取改变也许比FDG能更好地判断食管腺癌对新辅助放化疗的疗效。这些初步结果表明,有必要进行更多病例的FLT-PET/CT显像,以确认其价值。

关键词： FDG FLT PET/CT 食管癌放射治疗疗效新辅助放化疗

ULTRASONIC PLACENTAL GRADING IN HIGH RISK PREGNANCY

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1985年第9期

作者：邹玲 harvey A Gabert William j.McGanity

264 high risk pregnancy patients were studied by B mode ultrasound for placental grading and biparietal diameter (BPD) measurement. The Lecithinsphingomyelin (L/S) ratio, phosphatidyl-glyceroi (PG) and foam test were performed with 81 cases as control. Repeat cesarean sections were performed in 44 patients who did not have amniocentesis and their operation timing was based only upon placental grading, biparietal measurement and clinical examination. No respiratory distress syndrome (RDS) occurred in this group after delivery. This study shows that when BPD of≥ 8.7 cm is combined with Ⅰ, Ⅱ, or Ⅲ placental grading neonatal Dubowitz scores correspond to 38 weeks; neonatal birth weight is greater than 2,500 g and there is no RDS. Combined BPD of≥8.5 cm with a Grade Ⅲ placenta preclude the necessity for amniocentesis to prove fetal lung maturity. Grade Ⅲ placenta is more common in postdatism, chronic hypertension and preeclampsia and less common in diabetics.

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400 TW operation of Orion at ultra-high contrast

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High Power Laser Science and Engineering 2018年第3期6卷 79-84页

作者： Stefan Parker Colin Danson David Egan Stephen Elsmere Mark Girling Ewan harvey David Hillier Dianne Hussey Stephen Masoero j.mes McLoughlin Rory Penman Paul Treadwell David Winter Nicholas Hopps AWE plc Aldermaston Reading RG7 4PR UK

The Orion facility at the Atomic Weapons Establishment in the United Kingdom has the capability to operate one of its two 500 j. 500 fs short-pulse petawatt beams at the second harmonic, the principal reason being to increase the temporal contrast of the pulse on target. This is achieved post-compression, using 3 mrn thick type-1 potassium dihydrogen phosphate crystals. Since the beam diameter of the compressed pulse is ~600 mm, it is impractical to achieve this over the full aperture due to the unavailability of the large aperture crystals. Frequency doubling was originally achieved on Orion using a circular sub-aperture of 300 mm diameter. The reduction in aperture limited the output energy to 100 j. The second-harmonic capability has been upgraded by taking two square 300 mmx 300 mm sub-apertures from the beam and combining them at focus using a single paraboloidal mirror, thus creating a 200 j. 500 fs, i.e., 400 TW facility at the second harmonic.

关键词： contrast frequency conversion ultra-high intensity

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战略防御仿真器性能评估

战略防御 1990年第1期 61-68页

作者：孙俊堂 C.Smith j.Farschon A.harvey j.Hill R.Nisley R.Plock

SD-PA是一个对集成模式的多层防御系统的各个阶段的闭环SDI 系统的有效性仿真。它是可变且有效的。因此它允许分析者对结构概念中的各部分进行折衷考虑并对大量的参数进行灵敏性研究。SDS-PA程序用主动搜索的方法确定SDI各部分之间的相... 详细信息

SD-PA是一个对集成模式的多层防御系统的各个阶段的闭环SDI 系统的有效性仿真。它是可变且有效的。因此它允许分析者对结构概念中的各部分进行折衷考虑并对大量的参数进行灵敏性研究。SDS-PA程序用主动搜索的方法确定SDI各部分之间的相互影响,这些部分指特定的战略威胁包括没有用任何人为的方法将作战过程分为助推段、后助推段、中段以及末段的防御抑制。SDI的每一部分（传感器和武器）都独立建模,使用者将威胁部分集中到一个特定数目的目标群,称为威胁管道,每个管道可以包括使用者指定的一定数目的导弹,这些导弹的状态每隔一定的时间进行采样,采样间隔或由使用者确定或由理想的分辨能力决定。使用胁胁管道保留了基本的几何关系和时间基准的灵敏性,而且不必对每个目标的弹道进行仿真。在要求分辨率很高的范围内,可以将每个威胁管道的目标群集中到一个助推器来运载。

关键词：仿真器防御 SDI系统

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