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Physiological plasticity in eucalyptus clones in the vegetative stage contributes to drought tolerance

林业研究:英文版 2023年第5期34卷 1549-1561页

作者： Vilma Marques ferreira Jailma ribeiro de Andrade Claudiana Moura dos Santos Sebastiao de Oliveira Maia Júnior Joao Correia de Araújo Neto Andrea Francisca da Silva Santos Vicente Mota da Silva Lucas Teles Bezerra Laurício Endres Laboratório de Fisiologia Vegetal Campus de Engenharia e Ciências AgráriasUniversidade Federal de AlagoasRio LargoAL57072-900Brazil Laboratório de Ciências Ambientais e Biodiversidade Departamento de Zootecnia.Centro de Ciências AgráriasUniversidade Estadual do MaranhãoSão LuísMA65300-000Brazil Laboratório de Propagação de Plantas.Campus de Engenharia e Ciências Agrárias Universidade Federal de AlagoasRio LargoAL57072-900Brazil Laboratório de Lepidoptera Museu de ZoologiaUniversidade de São PauloIpirangaSão PauloSP04263-000Brazil

With the expansion of eucalyptus crops to areas with severe water limitations,physiological studies involving eucalyptus clones to identify those that are tolerant to water stress become *** objective of this study was to assess morphological and physiological responses by eucalyptus clones subjected to drought stress and *** experiment consisted of three eucalyptus clones:VC865,I224 and I144 and two water regimes:control and water stress followed by rehydration,with six *** water potential,gas exchange,maximum quantum efficiency of photo systemⅡand plant height and stem diameter were evaluated under drought stress and ***6 d of rehydration,the number of leaves,leaf area and dry mass of root,leaf,stem and their total were *** clones showed intense reduction of gas exchange during the drought stress period,and only VC865 and 1144 showed rapid recovery with 3 d of *** 1224 showed greater reduction in height,stem diameter,number of leaves,water potential at midday(Ψ_(w)_(Midday)),and maximum quantum efficiency of photosystemⅡ(F_(v)/F_(m)).Clones VC865and T144 showed lower reductions inΨ_(wMidday)and F_(v)/F_(m) under ***865 had lower reductions in leaf number,leaf area and higher leaf dry mass,while clone I144 had higher height and lower reduction in root dry mass *** these clones showed higher water use efficiency with 3d of *** different phenotypic plasticities gave the clones VC865 and 1144 efficient mechanisms of acclimatization to stress and more drought tolerance,enhancing their greater capacity for recovery after stress,which allowed lower dry mass *** 1224,however,was more susceptible to drought stress,undergoing greater physiological damage with only partial recovery during rehydration.

关键词： Drought Eucalyptus species Gas exchanges Post-stress Root dry mass

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Challenges and opportunities of machine learning control in building operations

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Building Simulation 2023年第6期16卷 831-852页

作者： Liang Zhang Zhelun Chen Xiangyu Zhang amanda Pertzborn Xin Jin The University of Arizona 1209 E 2nd StTucsonAZUSA Drexel University 3141 Chestnut StPhiladelphiaPAUSA National Renewable Energy Laboratory 15013 Denver W PkwyGoldenCOUSA National Institute of Standards and Technology 100 Bureau DrGaithersburgMDUSA

Machine learning control(MLC)is a highly flexible and adaptable method that enables the design,modeling,tuning,and maintenance of building controllers to be more accurate,automated,flexible,and *** research topic of MLC in building energy systems is developing rapidly,but to our knowledge,no review has been published that specifically and systematically focuses on MLC for building energy *** paper provides a systematic review of MLC in building energy *** review technical papers in two major categories of applications of machine learning in building control:(1)building system and component modeling for control,and(2)control process *** identify MLC topics that have been well-studied and those that need further research in the field of building operation *** also identify the gaps between the present and future application of MLC and predict future trends and opportunities.

关键词： machine learning building operation control building energy system reinforcement learning

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Development of a Bias Compensating Q-Learning Controller for a Multi-Zone HVAC Facility

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IEEE/CAA Journal of Automatica Sinica 2023年第8期10卷 1704-1715页

作者： Syed Ali Asad Rizvi amanda J.Pertzborn Zongli Lin IEEE the Department of Electrical and Computer Engineering Tennessee Technological UniversityCookevilleTN 38505 USA the Mechanical Systems and Controls Group in the Building Energy and Environment Division at the National Institute of Standards and Technology(NIST) GaithersburgMD 20899 USA the Charles L.Brown Department of Electrical and Computer Engineering University of VirginiaCharlottesvilleVA 22904-4743 USA

We present the development of a bias compensating reinforcement learning(RL)algorithm that optimizes thermal comfort(by minimizing tracking error)and control utilization(by penalizing setpoint deviations)in a multi-zone heating,ventilation,and air-conditioning(HVAC)lab facility subject to unmeasurable disturbances and unknown *** is shown that the presence of unmeasurable disturbance results in an inconsistent learning equation in traditional RL controllers leading to parameter estimation bias(even with integral action support),and in the extreme case,the divergence of the learning *** demonstrate this issue by applying the popular Q-learning algorithm to linear quadratic regulation(LQR)of a multi-zone HVAC environment and showing that,even with integral support,the algorithm exhibits bias issue during the learning phase when the HVAC disturbance is unmeasurable due to unknown heat gains,occupancy variations,light sources,and outside weather *** address this difficulty,we present a bias compensating learning equation that learns a lumped bias term as a result of disturbances(and possibly other sources)in conjunction with the optimal control *** results show that the proposed scheme not only recovers the bias-free optimal control parameters but it does so without explicitly learning the dynamic model or estimating the disturbances,demonstrating the effectiveness of the algorithm in addressing the above challenges.

关键词： HVAC control optimal tracking Q-learning reinforcement learning(RL)

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The new wave of p75 neurotrophin receptor targeted therapies

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Neural Regeneration Research 2022年第1期17卷 95-96页

作者： amanda M.Crooks Rick B.Meeker UNC School of Medicine University of North CarolinaChapel HillNCUSA(Crooks AM)Department of NeurologyUniversity of North CarolinaChapel HillNCUSA

Neurotrophins have been recognized for decades for their beneficial effects on growth,survival,and maintenance in the central nervous system,all of which suggest potential therapeutic *** understanding and harnessing the activity of neurotrophins has proven difficult,the past several years have seen significant strides in the development of deliverable therapies that modulate neurotrophin activity(Shen et al.,2019;Yang et al.,2020;Xie et al.,2021).These recent studies have primarily focused on the multifunctional p75 neurotrophin receptor(p75NTR)which is upregulated in central nervous system disease and injury,thus offering a unique target for intervention.

关键词： al. therapies p75

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NDRank: optimised parallel search for weather analogues

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Big Earth Data 2023年第2期7卷 276-297页

作者： David Martins Miguel ferreira João Nuno Silva Instituto Superior Técnico Universidade de LisboaLisboaPortugal Caravela Energy Partners DarienConnecticutUSA Distributed Parallel and Secure Systems GroupINESC-ID LisboaLisboaPortugal

Global meteorology data are now widely used in various areas, but one of its applications, weather analogues, still require exhaustive searches on the whole historical data. We present two optimisations for the state-of-the-art weather analogue search algorithms: a parallelization and a heuristic search. The heuristic search (NDRank) limits of the final number of results and does initial searches on a lower resolution dataset to find candidates that, in the second phase, are locally validated. These optimisations were deployed in the Cloud and evaluated with ERA5 data from ECMWF. The proposed parallelization attained speedups close to optimal, and NDRank attains speedups higher than 4. NDRank can be applied to any parallel search, adding similar speedups. A substantial number of executions returned a set of analogues similar to the existing exhaustive search and most of the remaining results presented a numerical value difference lower than 0.1%. The results demonstrate that it is now possible to search for weather analogues in a faster way (even compared with parallel searches) with results with little to no error. Furthermore, NDRank can be applied to existing exhaustive searches, providing faster results with small reduction of the precision of the results.

关键词： Multidimensional arrays weather analogues search parallel computing algorithm optimisation

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Direct Electrochemical Determination of Glyphosate Herbicide Using a Screen-Printed Carbon Electrode Modified with Carbon Black and Niobium Nanoparticles

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Journal of Analysis and Testing 2023年第4期7卷 425-434页

作者： Julia Oliveira Fernandes Cassiano Augusto Rolim Bernardino Juliana dos Santos Fernandes Claudio Fernando Mahler Bernardo ferreira Braz Luiz Henrique Carpenter dos Santos Rodrigo JoséCorrêa Ricardo Erthal Santelli Braulio Soares Archanjo Emerson Schwingel ribeiro Fernando Henrique Cincotto Departament of Analytical Chemistry Institute of ChemistryFederal University of Rio de JaneiroRio de Janeiro 21941-909Brazil Departament of Civil Engineering COPPEFederal University of Rio de JaneiroRio de Janeiro 21941-598Brazil National Institute of Science&Technology of Bioanalytics(INCTBio) CampinasSão Paulo 13083-862Brazil Departament of Inorganic Chemistry Institute of ChemistryFederal University of Rio de JaneiroRio de Janeiro 21941-909Brazil Unesp National Institute of Alternative Technologies for DetectionToxicological Assessment and Removal of Micropollutants and Radioactives(INCT-DATREM)AraraquaraSão Paulo 14800-060Brazil National Institute of Metrology Quality and TechnologyInmetroAv.Nossa Senhora das Graças50XerémDuque de Caxias 25250-020Brazil

Glyphosate is a herbicide that has been widely used worldwide and is used in agricultural areas to control weeds and unwanted *** sensors developed from different nanomaterials have high efficiency,excellent cost-benefit,and fast analysis time for detecting traces of environmental *** study aimed to produce an electrochemical sensor with disposable screen-printed electrodes based on carbon black modified with niobium nanoparticles to determine glyphosate in aqueous *** morphology,structure and electrochemical performance of the sensor were characterized by scanning electron microscopy,energy-dispersive X-ray spectroscopy,X-ray diffraction and cyclic *** pulse voltammetry in BR buffer solution at pH 5.0 allowed the generation of a method to quantify glyphosate concentration in a linear range of 5.90-172.30μmol/L(1.00-29.13μg/mL),with a limit of detection calculated at 3.07μmol/L(0.52μg/mL).The method efficiently quantified glyphosate in real water samples and showed no interference from K^(+),Na^(+),Ca^(2+),Mg^(2+)ions or thiamethoxam,imidacloprid and carbendazim pesticides.

关键词： Glyphosate Electrochemical sensor Carbon black Niobium nanoparticles

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Soil organic carbon storage in forest restoration models and environmental conditions

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Journal of Forestry Research 2022年第4期33卷 1123-1134页

作者： Ranieri ribeiro Paula Miguel Calmon Maria Leonor Lopes-Assad Eduardo de SáMendonça Departamento de Agronomia Programa de Pós-Graduação em Produção VegetalUniversidade Federal do Espírito SantoAlto UniversitárioGuararemaAlegreEspírito Santo CEP 29500-000Brazil World Resources Institute SalvadorBahia CEP 40290-040Brazil Departamento de Recursos Naturais e Proteção Ambiental Universidade Federal de São CarlosArarasSão Paulo CEP 13600-970Brazil

The scale of forest and landscape restoration is expected to increase during the UN Decade on Ecosystem Restoration and its contribution to the provision of critical ecosystem services to *** models of forest restoration may improve ecosystem services,including soil organic carbon(SOC)storage.A review was carried out to access:(1)the variability of SOC storage between worldwide forest restoration models and,(2)the effects of climate,soil class,soil texture,and vegetation type on SOC *** reviewed 119 primary studies with information on SOC and soil texture for different forest restoration *** restoration models were grouped into four categories:natural regeneration,monocultures,agroforestry,and mixed *** data was extracted from these four restoration models,other land uses(cropland,bare land,grassland,and natural forest),climate regimes,and soil *** SOC storage in the forest restoration models and other land uses at a global scale ranged between 0.1 to 514 Mg ha^(-1).The overall mean value for SOC storage was higher for natural regeneration(112 Mg ha^(-1)),followed by agroforestry(74 Mg ha^(-1)),mixed forest(73 Mg ha^(-1)),and monocultures(68 Mg ha^(-1)).However,the average SOC storage was similar among the four restoration models in the moist warm climate *** SOC storage mean value in the moist cool zone was 23%higher than the dry cool zone(81 and 62 Mg ha^(-1),respectively),and 50%higher for the moist warm zone when compared to the dry warm climatic zone(74 and 38 Mg ha^(-1),respectively).The SOC storage of the restoration models was positively related to soil depth(0.59;p<0.01),clay content(0.29;p<0.01),and stand age(0.17;p<0.01).Globally,the mean values of SOC storage were 26,66,and 139 Mg ha^(-1) at zero-10,zero-30,and zero-100 cm depths,*** addition,sandy soils showed smaller mean values of SOC storage than medium to clay soils,especially in deeper soil ***,SOC storage was positively re

关键词： Forest restoration Land uses Soil type Soil texture Climate

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Laser texturing of piston ring for tribological performance improvement

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Friction 2023年第10期11卷 1895-1905页

作者： Rita ferreira Óscar CARVALHO Luís SOBRAL Sandra CARVALHO Filipe SILVA CMEMS-UMinho University of MinhoGuimarães 4800058Portugal LABBELS-Associate Laboratory Guimarães 4800058Portugal CEMMPRE-Center for Mechanical Engineering Materials and ProcessesUniversity of CoimbraRua Luís Reis SantosCoimbra 3030-788Portugal MAHLE Componentes de MotoresS.A.Núcleo Industrial de MurtedeCantanhede 3060-372Portugal

The radial surface coating layer of compression piston rings is used to improve their wear resistance during the internal combustion engine ***,at top dead centers,the friction coefficient of the piston ring–cylinder liner pair is detrimental to the engine’s tribological *** this work,dimples with different texture dimensions and densities were tested in a home-developed *** friction coefficient was measured for all samples,and for those with the best results,their wear resistance was *** texture with an aspect ratio of 0.25 and a density area of 15%reported the best tribological results.

关键词： piston ring surface texture friction wear

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Multiple hepatic infarctions secondary to diabetic ketoacidosis:A case report

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World Journal of Hepatology 2022年第11期14卷 1977-1984页

作者： Vitoria Mikaelly da Silva Gomes Gustavo de Sousa Arantes ferreira Luise Cristina Torres Rubim de Barros Barbara Moreira ribeiro Trindade dos Santos Lorenna Paulinelli Bahia Vieira Department of General Surgery Hospital das Clinicas da Universidade Federal de Minas GeraisBelo Horizonte 30130100Minas GeraisBrazil Instituto de Cardiologia do Distrito Federal Brasilia 70673900Distrito FederalBrazil Department of General Surgery Hospital Metropolitano Doutor Celio de CastroBelo Horizonte 30620090Minas GeraisBrazil

BACKGROUND Hepatic infarctions(HI)are ischemic events of the liver in which a disruption in the blood flow to the hepatocytes leads to focal ischemia and *** HI are due to occlusive events in the liver’s blood vessels,but non-occlusive HI may *** are associated with disruption of microvasculature,such as in diabetic *** HI usually presents as peripheral lesions with clear borders,irregular nodular lesions may occur,indistinguishable from liver neoplasms and presenting a diagnostic *** SUMMARY We report a case of multiple extensive HI in a patient with poorly controlled diabetes mellitus,who first presented to the emergency room with diabetic *** then developed jaundice,thrombocytopenia,and a marked elevation of serum *** ultrasound of the liver showed the presence of multiple irregular *** investigation with a computerized tomography scan confirmed the presence of multiple hypoattenuating nodules with irregular borders and heterogeneous *** lesions were considered highly suggestive of a primary neoplasm of the *** the patient was clinically stable,his bilirubin levels remained persistently elevated,and he underwent an ultrasound-guided percutaneous biopsy of the largest *** results revealed extensive ischemic necrosis of hepatocytes,with no signs of associated *** months after the symptoms,the patient showed great improvement in all clinical and laboratory parameters and extensive regression of the lesions on imaging *** This case highlights that diabetic ketoacidosis can cause non-occlusive HI,possibly presenting as nodular lesions indistinguishable from neoplasms.

关键词： Hepatic infarction Non-occlusive infarcts Diabetic ketoacidosis Pseudotumor of the liver Liver infarcts Case report

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Targeting BCL2 pathways in CLL: a story of resistance and ingenuity

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Cancer Drug Resistance 2023年第4期6卷 828-837页

作者： amanda Reyes Tanya Siddiqi Hematology&Oncology City of HopeDuarteCA 91010USA Hematology/HCT City of HopeDuarteCA 91010USA

Chronic lymphocytic leukemia(CLL)is common amongst leukemic malignancies,prompting dedicated investigation throughout the *** the last decade,the treatment for CLL has significantly advanced with agents targeting B-cell lymphoma 2(BCL2),Bruton's tyrosine kinase,and *** agents or combinations of these targets have proven ***,resistance to one or multiple of the new treatment targets *** review investigates various mechanisms of resistance to BCL2 inhibitors,including mutations in BCL2,alterations in the Bcl protein pathway,epigenetic modifications,genetic heterogeneity,Richter transformation,and alterations in oxidative ***,the review will discuss potential avenues to overcome this resistance with novel agents such as bispecific antibodies,Bruton's tyrosine kinase(BTK)degraders,non-covalent BTK inhibitors,and chimeric antigen receptor T(CART).

关键词： BCl-2 inhibitors apoptosis CLL resistance tumor microenvironments cell cycle regulation genetic mutations epigenetics richter transformation

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