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Advances in Bioscience and Biotechnology 2013年第10期4卷 63-74页

作者： Aaesha I. Sheikh Deborah Caswell Cynthia Dick Spencer Gang Justin Jarrell Ankita Kohli amanda lieu Jared Lumpe Meghan Garrett Jennifer Parker Craig Stephens Biology Department Santa Clara University 500 El Camino Real Santa Clara USA

The oligotrophic freshwater bacterium Caulobacter crescentus encodes a cluster of genes (CC_1487 to CC_1495) shown here to be necessary for metabolism of D-galacturonate, the primary constituent of pectin, a major plant polymer. Sequence analysis suggests that these genes encode a version of the bacterial hexuronate isomerase pathway. A conserved 14 bp sequence motif is associated with promoter regions of three operons within this cluster, and is conserved in homologous gene clusters in related alpha-Proteobacteria. Embedded in the hexuronate gene cluster is a gene (CC_1489) encoding a member of the LacI family of bacterial transcription factors. This gene product, designated here as HumR (hexuronate metabolism regulator), represses expression of the uxaA and uxaC operon promoters by binding to the conserved operator sequence. Repression is relieved in the presence of galacturonate or, to a lesser extent, by glucuronate. Other genes potentially involved in pectin degradation and hexuronate transport are also under the control of HumR. Adoption of a LacI-type repressor to control hexuronate metabolism parallels the regulation of xylose, glucose, and maltose utilization in C. crescentus, but is distinct from the use of GntR-type repressors to control pectin and hexuronate utilization in gamma-Proteobacteria such as Escherichia coli.

关键词： Caulobacter Galacturonate LacI

Current status and future of targeted peptide receptor radionuclide positron emission tomography imaging and therapy of gastroenteropancreatic-neuroendocrine tumors

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World Journal of Gastroenterology 2022年第17期28卷 1768-1780页

作者： Neil Grey Michael Silosky Christopher H lieu Bennett B Chin Radiology-Nuclear Medicine University of Colorado School of MedicineAnschutz Medical CampusAuroraCO 80045United States Department of Radiology University of Colorado School of MedicineAnschutz Medical CampusAuroraCO 80045United States Medical Oncology University of Colorado School of MedicineAnschutz Medical CampusAuroraCO 80045United States

Theranostics is the highly targeted molecular imaging and therapy of *** peptide receptor radionuclide therapy has taken the lead in demonstrating the safety and effectiveness of this molecular approach to treating ***,well-differentiated gastroenteropancreatic neuroendocrine tumors may be most effectively imaged and treated with DOTATATE *** review the current practice,safety,advantages,and limitations of DOTATATE based ***,we briefly describe the exciting new areas of development and future directions of gastroenteropancreatic neuroendocrine tumor theranostics.

关键词： DOTATATE Theranostics Gastroenteropancreatic neuroendocrine tumors 68Ga DOTATATE 177Lu DOTATATE Review

Additive‑Driven Interfacial Engineering of Aluminum Metal Anode for Ultralong Cycling Life

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Nano-Micro Letters 2023年第2期15卷 143-160页

作者： Sonal Kumar Prasad Rama Gaoliang Yang Wei Ying lieu Deviprasath Chinnadurai Zhi Wei Seh Institute of Materials Research and Engineering Agency for ScienceTechnology and Research(A*STAR)2 Fusionopolis WayInnovisSingapore 138634Singapore Department of Chemistry and Molecular Biology University of Gothenburg41125 GothenburgSweden Pillar of Engineering Product Development Singapore University of Technology and Design8 Somapah RoadSingapore 487372Singapore

Rechargeable Al batteries(RAB)are promising candidates for safe and environmentally sustainable battery systems with low-cost ***,the currently used aluminum chloridebased electrolytes present a significant challenge to commercialization due to their corrosive ***,we report for the first time,a novel electrolyte combination for RAB based on aluminum trifluoromethanesulfonate(Al(OTf)_(3))with tetrabutylammonium chloride(TBAC)additive in *** presence of a mere 0.1 M of TBAC in the Al(OTf)_(3) electrolyte generates the charge carrying electrochemical species,which forms the basis of reaction at the *** reduces the charge transfer resistance and the surface activation energy at the anode surface and also augments the dissociation of Al(OTf)_(3) to generate the solid electrolyte interphase *** electrolyte’s superiority directly translates into reduced anodic overpotential for cells that ran for 1300 cycles in Al plating/stripping tests,the longest cycling life reported to *** unique combination of salt and additive is non-corrosive,exhibits a high flash point and is cheaper than traditionally reported RAB electrolyte combinations,which makes it commercially *** this report,we address a major roadblock in the commercialization of RAB and inspire equivalent electrolyte fabrication approaches for other metal anode batteries.

关键词： Aluminum-ion batteries Solid electrolyte interphase Electrolyte additives Non-aqueous electrolytes

Pediatric firearm-associated fractures:Analysis of management and outcomes

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World Journal of Clinical Pediatrics 2021年第6期10卷 151-158页

作者： Virginia lieu Laura A Carrillo Nirav K Pandya Ishaan Swarup Department of Orthopaedics St.Mary’s Medical CenterSan FranciscoCA 94117United States Medical College of Wisconsin MilwaukeeWI 53226United States Department of Orthopaedics UCSF Benioff Children’s Hospital OaklandOaklandCA 94609United States

BACKGROUND Firearm-associated injuries(FAIs)are among the leading causes of morbidity and mortality in children living in the United *** victims of such injuries survive,but may experience compromised function related to musculoskeletal *** complex firearm-associated fractures(FAFs)often require specialized orthopaedic,vascular,and plastic surgical intervention,there is minimal research describing their management and *** purpose of this study is to describe the epidemiology and presentation of pediatric FAFs,as well as evaluate the management and outcomes of these *** To describe the epidemiology and presentation of pediatric FAFs,as well as evaluate the management and outcomes of these *** A retrospective chart review was performed at a major,pediatric level 1 trauma *** study included patients aged 18 or younger who presented with FAIs between *** data was collected on patients with FAFs including demographic and clinical data such as age,sex,race,payor type,fracture location,injury severity score(ISS),and radiographic and clinical *** management of FAFs was analyzed as well as need for readmission and *** statistics were used to summarize the results and univariate analyses were performed to assess differences between *** Between 2008 and 2018,there were a total of 61 patients who presented with *** this cohort,21 patients(34%)sustained FAFs(25 fractures)with a mean age of 11(Range:10 mo to 18 years old)at the time of *** 52%(n=11)of patients with FAFs were male,76%(n=8 and n=8,respectively)identified as black or other,and 71%(n=15)had government *** were most commonly noted in the upper extremity(n=7)and lower extremity(n=6).In patients with FAFs,the mean ISS at presentation was 11.38(Range:2-38),and 24%of patients(n=5)were classified as having a major *** were no significant differences in age,sex,r

关键词： Firearm Fracture Adolescent Gunshot Injury Pediatric

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巴黎地下墓室 600万人的长眠之所

环球人文地理 2012年第5期 102-107页

作者：肖文 Benh lieu Song 不详

巴黎地下墓穴是一个长约300公里的地下通道,里面有超过600万具尸骨,因此成为了世界上最大的藏骨库。在这个地下墓穴,尸骨就像柴禾堆一样,被堆放得整整齐齐,约2米高的"骨墙"一直延伸向黑暗深处。

关键词：地下通道黑暗深处

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高屈服强度钢在海洋焊接结构中的推广应用

国外钢铁 1989年第10期14卷 42-51页

作者： lieu.,HP 李常源

欧洲篇——巴黎地下墓室600万人的长眠之所

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城市地理 2013年第5期 4-11页

作者：肖文 Benh lieu Song(图)

欧洲是一块让人魂牵梦绕的土地。它面积不大，在七大洲中排名倒数第二．却因拥有秀美的风光，灿烂的文明，让人顶礼膜拜。那广袤无边的草原，巍峨挺立的雪山，休闲惬意的庄园，现代化气息浓郁的都市，尖顶高耸的哥特式教堂，斑驳的历史... 详细信息

欧洲是一块让人魂牵梦绕的土地。它面积不大，在七大洲中排名倒数第二．却因拥有秀美的风光，灿烂的文明，让人顶礼膜拜。那广袤无边的草原，巍峨挺立的雪山，休闲惬意的庄园，现代化气息浓郁的都市，尖顶高耸的哥特式教堂，斑驳的历史遗迹，无不吸引着游客前来—探究竟。

关键词：欧洲墓室巴黎哥特式教堂历史遗迹七大洲现代化庄园

INVESTIGATION OF THE TRANSITIONS OF OLIGO-POLYSULFONES BY DSC

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Chinese Journal of Polymer Science 1987年第3期5卷 228-233页

作者：董丽松郑国栋冯之榴 Changchun Institute of Applied Chemistry Academia Sinica Changchun Changchun Formerly E. T. L. Voong and Voong Tse-lieu

The transitions of bisphenol A and phenolphthalein o|igopolysulfones were investigated by DSC. It is found that both the oligomers have three transitions within the temperature range （230-550K） studied. Considering the strong dependence of the appearance of the two transitions, lower and higher than Tg, on the specimens’ thermal history, i. e., temperature and time of heat-treatment, and their particular molecular strueture, it is proposed that these two transitions are morphological in origin arid are due to the disordering of relatively short range order of very small regions, and to the disordering of relatively well-ordered intraor/and intermoleeular segments, respectively. Equations for linear relationship between Tg and 1/n for both the oligomers are given in the paper.

关键词： Oligo-polysulfone DSC transitions morphology

Radiation-induced anaplastic astrocytoma occurring 15 years after radiation therapy for cerebellar pilocytic astrocytoma:case report

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Radiation-induced anaplastic astrocytoma occurring 15 years ...

Pilocytic astrocytoma of the cerebellum in children

中国抗癌协会神经肿瘤专业委员会第八届学术会议

作者： Shen-long Howng Ann-Shung lieu Joon-Khim Loh Chee-Yin Chai Aij-Lie Kwan Chih-Jen Wang Department of Neurosurgery PathologyKaohsiung Medical University and Hospital

＜正＞Malignant gliomas have been reported to arise in the radiation field of patients with previously radiation-treated brain *** the incidence of radiation-induced brain tumors is low at approximately 1%,it is an im...

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Pilocytic astrocytoma of the cerebellum in children