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Fundamental motor skills,screen-time,and physical activity in preschoolers

Journal of Sport and Health Science 2019年第2期8卷 114-121页

作者： e.Kipling Webster Corby K.Martin amanda e.staiano School ofKinesiology Louisiana State University Pennington Biomedical Research Center Louisiana State University

Purpose: To examine the associations among preschoolers fundamental motor skills, screen-time, physical activity(PA), and sedentary behavior(SB).Methods: Children ages 3à4 years were enrolled in a prospective observational trial of PA. Trained assessors conducted the Test of Gross Motor Development-3 rd edition(TGMD-3), and the Movement Assessment Battery for Children-2 nd edition, and parent-reported child screen-time and sociodemographic information. Children wore an accelerometer for 7 days to examine SB and total PA(TPA). TPA was further characterized as moderateto-vigorous PA(MVPA) or vigorous PA(VPA). Mixed linear models were calculated, controlling for age(for TGMD-3), sex, household income, and accelerometer wear time(for accelerometry models), with childcare center as a random effect. The primary analysis reported on the cross-sectional baseline data of 126 children with complete fundamental motor skill and screen-time data; a subanalysis included 88 children with complete accelerometry ***: Children were 3.4 § 0.5 years of age(54% girls; 46% white, 42% African American, 12% other). A total of 48% lived in households at or below the federal poverty level. Children engaged in 5.1 § 3.6 h/day of screen-time. Children's screen-time was inversely related to the Movement Assessment Battery for Children-2 nd edition, manual dexterity skills percentile(b(Se) = ?1.7(0.8), p = 0.049). In the accelerometry subsample,children engaged in 5.9 § 0.9 h/day of TPA of which 1.7 § 0.6 h/day was MVPA. Boys engaged in more MVPA and VPA and less SB compared with girls(all p er TGMD-3, total score(b(Se) = 0.4(0.2), p = 0.017) and locomotor score(b(Se) = 0.7(0.3), p = 0.018) were associated with more VPA but not with TPA or MVPA. Screen-time and television in the bedroom were not related to SB, TPA, MVPA, or ***: Children's motor skills were positively related to VPA but inversely related to screen-time. Further inquiry into the implications of

关键词： Fundamental motor skills Physical activity Preschool Screen-time

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Twelve weeks of dance exergaming in overweight and obese adolescent girls:Transfer effects on physical activity,screen time,and self-efficacy

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Journal of Sport and Health Science 2017年第1期6卷 4-10,127页

作者： amanda e.staiano Robbie A.Beyl Daniel S.Hsia Peter T.Katzmarzyk Robert L.Newton Jr Pennington Biomedical Research Center Baton RougeLA 70808USA

Background: Given the low levels of physical activity(PA) among adolescent girls in the US, there is a need to identify tools to motivate increased PA. Although there is limited evidence that adolescents transfer PA from one context to another, exergames(i.e., video games that require gross motor activity) may act as a gateway to promote overall PA outside game play. The purpose of this study was to examine potential transfer effects(i.e., influences on external behaviors and psychological constructs) of a 12-week exergaming intervention on adolescent girls' PA, screen time,and self-efficacy toward PA, as well as the intrinsic motivation of ***: Participants were 37 girls aged 14–18 years(65% African American, 35% white) who were overweight or obese(body mass index ≥ 85 th percentile) and were recruited from the community via school, physicians, news media, and social media websites. Adolescents were randomly assigned to a 12-week group exergaming intervention(thirty-six 60 min sessions of group-based dance exergaming in a research laboratory using Kinect for Xbox360(Microsoft Corporation, Redmond, WA, USA)) or to a no-treatment control group. Outcome variables included objectively measured PA(total) and self-reported leisure-time PA(discretionary time only) 1 week before vs. 1 week after the intervention; selected type and intensity of PA when placed in a gym setting for 30 min("cardio free choice"); screen time; self-efficacy toward PA; and intrinsic motivation toward ***: Attendance at the exergaming sessions was high(80%). Compared with the control group, the intervention group self-reported an increase in PA(p = 0.035) and fewer hours watching television or videos(p = 0.01) after the intervention, but there were no significant differences in sedentary, light, moderate, or vigorous PA measured by accelerometry. The intervention group significantly improved self-efficacy toward PA(p = 0.028). The intervention group highly rated intri

关键词： Active video games Leisure activity Motivation Screen time Self-efficacy Television

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Advances and challenges in diagnosing and managing adult autoimmune enteropathy

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World Journal of Gastroenterology 2025年第2期31卷 128-131页

作者： Grigorios Christodoulidis Sara e Agko Marina N Kouliou Konstantinos e Koumarelas Dimitris Zacharoulis Department of General Surgery University Hospital of LarissaLarissa 41110Greece Department of Intensive Care Unit Asklepios Paulinen Clinic WiesbadenWiesbaden 65197Germany Department of emergency Medicine General Hospital of LarissaLarissa 41221Greece Department of Surgery University Hospital of LarissaLarissa 41334Greece

Autoimmune enteropathy(AIe)is a rare immune mediated disorder primarily affecting children,characterized by chronic diarrhea,malabsorption,vomiting,weight loss and villous *** has also been observed in adults presenting diagnostic and treatment challenges due to its overlap with other gastrointestinal disorders such as celiac *** diagnostic criteria for AIe include small bowel villous atrophy,lack of response to dietary restrictions,presence of anti-enterocyte antibodies,and predisposition to autoimmunity without severe *** criteria emphasize characteristic histological findings and exclusion of other causes of villous *** is associated with various autoimmune disorders and can present with overlapping features with Celiac disease,including villous atrophy but without significant intraepithelial *** primarily involves immunosuppression using corticosteroids,calcineurin inhibitors,and anti-tumor necrosis factor therapy,alongside nutri-tional *** the challenges,understanding AIe’s diverse manifest-ations and improving diagnostic criteria are essential for effective management and improved patient *** research is needed to elucidate the pathogenesis,disease progression and long-term outcomes of AIe.

关键词： Autoimmune enteropathy Diagnosis Prognosis Adult autoimmune enter-opathy and challenges Autoimmune enteropathy and treatment Autoimmune enteropathy and diagnostic criteria Pathophysiology of autoimmune enteropathy

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A Finite element Method for a Phase Field Model of Nematic Liquid Crystal Droplets

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Communications in Computational Physics 2019年第1期25卷 155-188页

作者： amanda e.Diegel Shawn W.Walker Department of Mathematics Louisiana State UniversityBaton RougeLA 70803-4918USA

We develop a novel finite element method for a phase field model of nematic liquid crystal *** continuous model considers a free energy comprised of three components:the ericksen’s energy for liquid crystals,the Cahn-Hilliard energy representing the interfacial energy of the droplet,and an anisotropic weak anchoring energy that enforces a condition such that the director field is aligned perpendicular to the interface of the *** of the model are for finding minimizers of the free energy and exploring gradient flow *** present a finite element method that utilizes a special discretization of the liquid crystal elastic energy,as well as mass-lumping to discretize the coupling terms for the anisotropic surface tension ***,we present a discrete gradient flow method and show that it is monotone energy ***,we show that global discrete energy minimizersΓ-converge to global minimizers of the continuous *** conclude with numerical experiments illustrating different gradient flow dynamics,including droplet coales-cence and break-up.

关键词： Nematic liquid crystal phase field ericksen’s energy Γ-convergence gradient flow

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Commentary on “Does light-intensity physical activity moderate the relationship between sitting time and adiposity markers in adolescents?”

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Journal of Sport and Health Science 2024年第4期13卷 453-454页

作者： Barbara e.Ainsworth amanda M.Ferland School of exercise and Health Shanghai University of SportShanghai 200433China Department of Orthopedics Tongji UniversityShanghai 200092China

In the September 2022 issue of the Journal of Sport and Health Science,Ayala et al.1 published results from a cross-sectional study where they tested the hypothesis that light intensity physical activity(LIPA,1.6-2.9 metabolic equivalents(MeTs))moderates the relationship between sitting time and adiposity in 219 Australian adolescents aged 14±1.6 years(mean±SD).

关键词： metabolic light

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Assessment of nutrients and conductivity in the Wachusett Reservoir watershed:An investigation of land use contributions and trends

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International Soil and Water Conservation Research 2024年第2期12卷 337-350页

作者： amanda Carneiro Marques Carlos eduardo Veras emily Kumpel John e.Tobiason Christian D.Guzman Dept of Civil and environmental engineering University of Massachusetts AmherstMA01003USA

The quality of drinking water for the Boston Metropolitan Area,supplied by the Quabbin-Wachusett system,is impacted by environmental *** objectives of this study are to increase understanding of the role that small streams may play in degradation of reservoir quality by characterizing seasonal constituent patterns from 1998 to 2020 in the Wachusett Reservoir watershed and by developing enhanced modeling *** monitoring(1998–2012)exhibited increased loads due to increasing flows despite declining solute *** present study analyzed seasonal nitrate(NO3)and total phosphorus(TP)concentration and load trends from 2012 to 2020 across 11 *** conductivity(SC)was also assessed to evaluate the impacts of road salt *** 2012 to 2020,statistical results for mean nutrient concentrations suggest static or declining temporal trends,while SC in all tributaries exhibited increasing *** use data suggest association with altered drainage landscapes as potential sources of increased constituent *** with the highest concentrations of TP,NO3,and SC have the largest percentage of impervious and cultivated areas,two to three times greater than other *** flows were modeled using the airGR hydrological model,subsequently used to calculate ***,flow magnitude was a more important load driver than long-term nutrient concentrations,thus,showing that stream discharge controlled load *** the other hand,persistently high SC levels controlled the increasing SC load ***,many nutrient reduction management strategies demonstrated an important impact from 1998 to *** watershed programs aimed at reducing salt applications,concentrations in streams are increasing,indicating a long-term legacy of salt *** smaller tributaries represent a modest portion of the system,addressing these sources has the potential to further reduce the long-term ecological

关键词： Water quality Nutrients Road salt Long-term trends Pollutant loading

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enhancing perianal disease management with integrated physical and psychological approaches

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World Journal of Clinical Cases 2025年第2期13卷 59-63页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal *** study sheds light on how illness perception,anxiety,and depression significantly influence recovery *** et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor *** article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for *** study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.

关键词： Perianal disease Post-operative recovery Anxiety Depression Pain management emotional well-being Multidisciplinary approach

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Brain-derived neurotrophic factor alterations and cognitive decline in schizophrenia:Implications for early intervention

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World Journal of Psychiatry 2025年第1期15卷 189-193页

作者： Uchenna e Okpete Haewon Byeon Department of Digital Anti-aging Healthcare(BK21) Inje UniversityGimhae 50834South Korea

This manuscript explores the recent study by Cui et al which assessed the interplay between inflammatory cytokines and brain-derived neurotrophic factor(BDNF)levels in first-episode schizophrenia *** study revealed that higher levels of interleukin-6 and tumor necrosis factor-αcorrelated with reduced BDNF levels and poorer cognitive *** is a severe psy-chiatric disorder impacting approximately 1%of the global population,charac-terized by positive symptoms(hallucinations and delusions),negative symptoms(diminished motivation and cognitive impairments)and disorganized thoughts and *** research highlights the role of BDNF as a potential biomarker for early diagnosis and therapeutic *** findings from Cui et al’s study suggest that targeting neuroinflammation and enhancing BDNF levels may improve cognitive *** treatment approaches involve a com-bination of pharmacological and non-pharmacological interventions tailored to individual patient ***,monitoring cognitive and neuroinflammatory markers is essential for improving patient outcomes and quality of ***-quently,this manuscript highlights the need for an integrated approach to schizo-phrenia management,considering both clinical symptoms and underlying neuro-biological changes.

关键词： Schizophrenia Cognitive impairment Neuroinflammatory markers Brain-derived neurotrophic factor Interleukin Personalized treatment

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Changes in symmetry of anterior chamber following routine cataract surgery in non-glaucomatous eyes

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eye and Vision 2019年第1期6卷 148-155页

作者： Hanbin Lee Ieva Zukaite Valerie Juniat Maria e.Dimitry amanda Lewis Mayank A.Nanavat Presentations:The early results of this study were presented at the British Society for Refractive Surgery Congress BirminghamUnited KingdomMarch 2015 and the annual meeting of the Royal College of Ophthalmologist in May 2016

Background:To assess minimum and maximum changes in anterior chamber dimensions following routine cataract surgery in non-glaucomatous ***:Forty-two eyes(42 participants)underwent routine cataract surgery with same surgeon and were assessed preoperatively,1,3,6 and 12 months *** outcome measure:Angle-to-angle diameter(AAD)(at 0-180°,45-225°,90-270°,135-315°),Anterior-chamber-angle(ACA)(at 0°,45°,90°,135°,180°,225°,270° and 315°)and central anterior chamber depth(ACD)at all *** outcome measures:relationship to axial length(AL).Results:The mean AAD and ACA increased post-operatively in all meridians at all visits *** 12 months,there was a maximum change in AAD in horizontal meridian(506.55±468.71μm)and least in vertical meridian(256.31±1082.3μm).The mean percentage increase in ACA postoperatively was least at 90o(5%increase compared to 29–35%elsewhere).Central ACD deepened at all postoperative visits and this did not change over 12 *** was no correlation between AAD,ACA and ACD with AL at any ***:The AAD,ACA and ACD increases following cataract surgery in non-glaucomatous eyes,but at 12 months increase in AAD is least in vertical compared to horizontal ***,ACA was narrower(only 5%increase)superiorly compared to elsewhere(29–35%increase in ACA).This may have implications with regards to surgeries performed in the anterior chamber and corneal endothelial cell loss.

关键词： Anterior chamber depth Anterior chamber angle Angle to angle diameter

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NeCAB family of neuronal calcium-binding proteins in health and disease

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Neural Regeneration Research 2025年第5期20卷 1236-1243页

作者： Diones Bueno Michael K.e.Schafer Sudena Wang Michael J.Schmeisser Axel Methner Institute for Molecular Medicine University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Department of Anesthesiology University Medical Center of the Johannes Gutenberg-UniversityMainzGermany Institute of Anatomy University Medical Center of the Johannes Gutenberg-UniversityMainzGermany

The N-terminal eF-hand calcium-binding proteins 1–3(NeCAB1–3) constitute a family of predominantly neuronal proteins characterized by the presence of at least one eF-hand calcium-binding domain and a functionally less well characterized C-terminal antibiotic biosynthesis monooxygenase domain. All three family members were initially discovered due to their interactions with other proteins. NeCAB1 associates with synaptotagmin-1, a critical neuronal protein involved in membrane trafficking and synaptic vesicle exocytosis. NeCAB2 interacts with predominantly striatal G-protein-coupled receptors, while NeCAB3 partners with amyloid-β A4 precursor protein-binding family A members 2 and 3, key regulators of amyloid-β production. This demonstrates the capacity of the family for interactions with various classes of proteins. NeCAB proteins exhibit distinct subcellular localizations: NeCAB1 is found in the nucleus and cytosol, NeCAB2 resides in endosomes and the plasma membrane, and NeCAB3 is present in the endoplasmic reticulum and Golgi apparatus. The antibiotic biosynthesis monooxygenase domain, an evolutionarily ancient component, is akin to atypical heme oxygenases in prokaryotes but is not wellcharacterized in vertebrates. Prokaryotic antibiotic biosynthesis monooxygenase domains typically form dimers, suggesting that calcium-mediated conformational changes in NeCAB proteins may induce antibiotic biosynthesis monooxygenase domain dimerization, potentially activating some enzymatic properties. However, the substrate for this enzymatic activity remains uncertain. Alternatively, calcium-mediated conformational changes might influence protein interactions or the subcellular localization of NeCAB proteins by controlling the availability of protein–protein interaction domains situated between the eF hands and the antibiotic biosynthesis monooxygenase domain. This review summarizes what is known about genomic organization, tissue expression, intracellular localization, interac

关键词： calcium eF hand mitochondria nervous system signal transduction

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