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Quack Medicine

中华医学杂志 1916年第1期 84-91页

作者： ARTHUE stanley. M.D. Director of the Municipal Health Laboratory Shanghai

At the present time the subject of health is much before the public. Matters of health and disease are discussed at the dinner table and in the drawing room which a little while ago would have been reserved for the privacy of the consulting room. Consequently there is much imaginary disease and as a natural result a corresponding number of imaginary remedies. It is needless to say that there is also much real disease. A great deal is preventable or curable, but much of this suffering is not

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Calcium Homeostasis in Articular Chondrocytes of Two Different Animal Species

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Open Journal of Veterinary Medicine 2018年第8期8卷 119-133页

作者： Rachel White John stanley.Gibson Equine Department University Centre Myerscough College (University of Central Lancashire) Preston UK Department of Veterinary Medicine University of Cambridge Cambridge UK

Introduction: Intracellular calcium concentration ([Ca2+]i) is a critical parameter in cellular homeostasis, including articular chondrocytes. Perturbed [Ca2+]i of chondrocytes may be associated with joint disease. The objective of the study was to compare large animal models for investigating Ca2+ homeostasis in chondrocytes. Materials and Methods: The gross anatomy of the metacarpophalangeal joint (MCP) of cattle and sheep was compared, along with the effect of various manoeuvres used to study the mechanisms of Ca2+ homeostasis in chondrocytes from load-bearing areas. The gross anatomy was observed before and after dissection, and internal architecture was examined after sectioning. Cartilage thickness was measured with a digital micrometer. Chondrocyte yield was determined after isolation. Chondrocytes were incubated with Fura-2 and Ca2+i followed in different extracellular conditions. A hypotonic shock (HTS) was used to mimic removal of a load. Results: The results showed that ovids and bovids were skeletally immature and aspects of Ca2+ homeostasis were similar. Ovine chondrocytes had higher resting fluorescence, consistent with elevated resting Ca2+ levels. Results from ion substitution experiments were consistent with a role for Na+/Ca2+ exchange, and swelling-induced Ca2+ enters into the cytoplasm via the plasma membrane and intracellular stores. Conclusions: Ca2+ homeostasis in chondrocytes from both species behaved in a similar manner to HTS and ion substitutions. Differences in resting [Ca2+]i could be associated with species, stage of maturation, or Fura-2 itself and require further investigation. These findings contribute to our understanding of the physiology of articular cartilage in different species, and their potential use as models for studying joint disease in humans.

关键词： Chondrocytes Calcium Fura-2 Hypotonic Species

CARCINOMA OF CERVIX IN PREGNANCY

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中华医学杂志(英文版) 1935年第7期49卷 671-675页

作者： stanley.W. MORIS M.D. Department of Obstetrics and Gynecology Peiping Union Medical College Peiping

Carcinoma of the cervix associated with pregnancy is a rare condition but it is of such grave importance to both the mother and child that it demands careful consideration. The following cases emphasize the difficulti...

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Hydronephrosis and Ureteral Obstruction in Crohn’s Disease

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Open Journal of Urology 2013年第5期3卷 219-221页

作者： Robert Jansen stanley.Zaslau Division of Urology West Virginia University Morgantown USA

Hydronephrosis and ureteral obstruction are rare sequelae of Crohn’s disease. Chronic obstruction can ultimately lead to dysfunction of the affected kidney, and atypical presenting symptoms create pitfalls in diagnosis. Few reviews in the literature focus on this process and are limited to isolated case reports and case reviews. We performed a PubMed search using such terms as “Hydronephrosis” AND “Crohn’s disease” AND/OR “ureteral obstruction.” References from selected papers were reviewed for relevance and used for information-gathering as well. Ureteral obstruction most commonly occurs on the right side, due to ileal involvement. Clinical diagnosis is difficult, as symptoms are notably not genitourinary in origin;rather they are more musculoskeletal in nature. Treatment centers on disease control and temporary drainage of the affected kidney. Though rare, hydronephrosis and ureteral obstruction may develop as a result of inflammatory bowel disease. Due to atypical presenting symptoms, a high clinical suspicion is needed to affirm the diagnosis and ensure proper treatment.

关键词： Hydronephrosis Ureteral Obstruction Crohn’s Disease

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I'll Get Back to You

英语学习 1998年第6期 9-11页

作者： stanley.BING 佚林

Remorse is a terrible ***-wonderful in its own way too. How often do wefeel had about what we've done,even when we should? I'll tell *** never.

关键词： I’ll Get Back to You

Gigantic Genomes Provide Empirical Tests of Transposable Element Dynamics Models

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Genomics, Proteomics & Bioinformatics 2021年第1期19卷 123-139页

作者： Jie Wang Michael W.Itgen Huiju Wang Yuzhou Gong Jianping Jiang Jiatang Li Cheng Sun stanley.K.Sessions Rachel Lockridge Mueller CAS Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization&Ecological Restoration and Biodiversity Conservation Key Laboratory of Sichuan Province Chengdu Institute of BiologyChinese Academy of SciencesChengdu 610041China Department of Biology Colorado State UniversityFort CollinsCO 80523USA School of Information and Safety Engineering Zhongnan University of Economics and LawWuhan 430073China Institute of Apicultural Research Chinese Academy of Agricultural SciencesBeijing 100093China Biology Department Hartwick CollegeOneontaNY 13820USA

Transposable elements(TEs)are a major determinant of eukaryotic genome *** collective properties of a genomic TE community reveal the history of TE/host evolutionary dynamics and impact present-day host structure and function,from genome to organism *** rare cases,TE community/genome size has greatly expanded in animals,associated with increased cell size and changes to anatomy and ***,we characterize the TE landscape of the genome and transcriptome in an amphibian with a giant genome—the caecilian Ichthyophis bannanicus,which we show has a genome size of 12.2 *** are an important model system because the clade includes independent cases of genomic *** *** genome differs compositionally from other giant amphibian genomes,but shares a low rate of ectopic recombination-mediated *** examine TE activity using expression and divergence plots;TEs account for 15%of somatic transcription,and most superfamilies appear *** quantify TE diversity in the caecilian,as well as other vertebrates with a range of genome sizes,using diversity indices commonly applied in community *** synthesize previous models that integrate TE abundance,diversity,and activity,and test whether the caecilian meets model predictions for genomes with high TE *** propose thorough,consistent characterization of TEs to strengthen future comparative *** analyses will ultimately be required to reveal whether the divergent TE assemblages found across convergent gigantic genomes reflect fundamental shared features of TE/host genome evolutionary dynamics.

关键词： TE expression TE diversity index Genome size evolution Caecilian Transposon ecology

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A Trip to Las Vegas

英语学习 1995年第10期 40-45页

作者： stanley.Bing 宋玉梅

You don't need to be rich or drunk to love Las ***,*** THE WAY OUT:They don't serve meals on *** have to be on a nine-hour flight to Sri Lankato get *** the snack is quite enough for me in my currentfestive mood—an a... 详细信息

关键词： A Trip to Las Vegas 拉斯维加斯

Planning and Construction of Low Carbon Cities:The Relevance of Cost-Benefit Analysis

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China City Planning Review 2011年第3期20卷 17-25页

作者： stanley.C.T.YIP College of Urban and Environment Sciences Peking University

Cities are the major source of carbon dioxide emissions in China,and are the critical locations where emissions should be effectively *** a low carbon urban development model is the pathway towards reducing the emissions.A low carbon city development model means achieving efficient and effective urban growth through low energy consumption and low *** many local authorities in China have started to express the intention to construct low carbon cities,it is important to emphasize the need to apply a Cost-Benefit Analysis (CBA) to low carbon urban policies and development *** all policies and projects will have their costs and benefits to the society,the effects of the policies and projects on reducing emissions should be measured and assessed *** the setting up of an analysis framework to assess the costs and benefits,one can provide a scientific basis for decision making,and enhance the overall efficiency in the use of resources for the society as a whole.

关键词： climate change low carbon cities Cost-Benefits Analysis carbon dioxide emissions

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Update on gastric varices

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World Journal of Gastrointestinal Endoscopy 2014年第5期6卷 168-175页

作者： Maria Triantafyllou Adrian J stanley Department of Gastroenterology Glasgow Royal Infirmary

Although less common than oesophageal variceal haemorrhage, gastric variceal bleeding remains a serious complication of portal hypertension, with a high associated mortality. In this review we provide an update on the aetiology, classification and management of gastric varices, including acute bleeding, prevention of rebleeding and primary prophylaxis. We describe the optimum management strategies for gastric varices including drug, endoscopic and radiological therapies, focusing on recent published evidence.

关键词： Varices Gastric Portal hypertension Tissue glue Transjugular intrahepatic portosystemic shunt