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Review of practice informing data and current state of NCCN consensus guidelines in hepatobiliary cancers

Hepatobiliary Surgery and Nutrition 2023年第5期12卷 798-803页

作者： Virginia Corbett Daneng Li aman chauhan Division of Medical Oncology Department of MedicineIcahn School of Medicine at Mount SinaiNew YorkNYUSA Department of Medical Oncology&Therapeutics Research City of Hope Comprehensive Cancer CenterDuarteCAUSA Division of Medical Oncology Department of Internal MedicineSylvester Comprehensive Cancer CenterUniversity of MiamiMiamiFLUSA

The most important recent updates to the US National Comprehensive Cancer Network(NCCN)guidelines include the addition of new immunotherapy agents to the armamentarium for both hepatocellular carcinoma(HCC)and biliary tract cancers(1).The publication and subsequent the US Food and Drug Administration(FDA)approval of the Single Tremelimumab Regular Interval Durvalumab(STRIDE)regimen established in the phase III HIMALAYA trial(2)adds an important option for first-line systemic treatment of advanced HCC and was included in the NCCN guidelines with the 4.

关键词： National Comprehensive Cancer Network(NCCN) hepatocellular carcinoma(HCC) biliary cancers

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Adjuvant therapy for lung neuroendocrine neoplasms

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World Journal of Clinical Oncology 2021年第8期12卷 664-674页

作者： Robert A Ramirez Katharine Thomas Aasems Jacob Karen Lin Yvette Bren-Mattison aman chauhan Department of Medicine-Division of Hematology/Oncology Vanderbilt University Medical CenterNashvilleTN 37232United States Department of Hematology and Oncology Louisiana State University Health Sciences CenterNew OrleansLA 70112United States Division of Medical Oncology University of KentuckyLexingtonKY 40536United States Department of Oncology Brookwood Baptist HealthBirminghamAL 35209United States Department of Surgery Louisiana State University Health Sciences CenterNew OrleansLA 70112United States New Orleans Louisiana Neuroendocrine Tumor Specialists(NOLANETS) Ochsner Medical CenterKennerLA 70065United States

Pulmonary neuroendocrine neoplasms(NENs)represent a minority of lung cancers and vary from slower growing pulmonary carcinoid(PC)tumors to aggressive small cell lung cancer(SCLC).While SCLC can account for up to 15%of lung cancer,PCs are uncommon and represent about 2%of lung *** resection is the standard of care for early-stage PCs and should also be considered in early stage large cell neuroendocrine carcinoma(LCNEC)and *** treatment is generally accepted for aggressive LCNEC and SCLC,however,less well established for *** admit a lack of trials to support a high-level recommendation for adjuvant *** manuscript will discuss the role for adjuvant therapy in NENs and review the available literature.

关键词： Neuroendocrine Adjuvant therapy Lung Pulmonary carcinoid Small cell lung cancer

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