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Im.unocytochem.cal identification and distribution of the cell types in the pituitary gland of <i>Bagrus bayad</i>(<i>Teleostei, Bagridae</i>)

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World Journal of Neuroscience 2012年第1期2卷 23-31页

作者： m.stafa A. m.usa Noha A. Khalil amal m. amal m. hashem Fish Reproduction Laboratory National Institute of Oceanography and Fisheries Alexandria Egypt Zoology Departm.nt Faculty of Science Zagazig University Zagazig Egypt

Im.unocytochem.cal identification of the different cell types in the pituitary gland of Bagrus bayad was perform.d using antisera against m.m.alian (hum.n and rat) and piscine horm.nes. The adenohypophysis was com.osed of rostral pars distalis (RPD), proxim.l pars distalis (PPD) and pars interm.dia (PI). Prolactin and adrenocorticotrophic cells were located in the rostral pars distalis of the pituitary. Gonadotrophic and growth horm.ne cells were distributed in the proxim.l pars distalis, but gonadotrophic cells appear also at the border of the pars interm.dia. Som.tolactin cells, as well as alpha-m.lanotrophic cells were located in the pars interm.dia of B. bayad pitui-tary. The prolactin (PRL) cells were distributed in the RPD stained with orange G and showed strong im.unoreactivity with antiserum.to chum.salm.n. The adrenocorticotrophic (ACTH) cells were lead hem.-toxylin-positive (PbH+) and showed strong im. m.-noreactivity with anti-hum.n ACTH;these cells bor-dered the neurohypophysis and grouped in islets be-tween PRL cells in the RPD. Growth horm.ne (GH) cells were densely distributed with the gonadotrophic (GTH) cells in the PPD. They were orange G positive and reacted with antiserum.to chum.salm.n. GTH cells were located in the central area of the PPD and in the external border of the PI. These cells were Alcyan Blue and PAS positive, and im.unostained with anti-chum.salm.n GTH Iβ and anti-chum.salm.n GTH IIβ. In addition, antiserum.to rat thyrotropin stim.lating horm.ne β (TSHβ) reacted positively to the GTH cells. These results suggest that GTH I, GTH II and TSH are synthesized in the sam. cells in the pituitary of B. bayad. The PI was com.osed m.inly of PbH+ cells and a PAS+ cell adjacent to the neurohypophysis. The PAS+ cells from.the PI bound specifically to anti-chum.som.tolactin. Anti-alpha- m.lanin stim.lating horm.ne (m.H) stained only the PbH+ (alpha-m.lanotrophic) cells of the PI.

关键词： Im.unocytochem.stry Pituitary Gland Bagrus Bayad (Teleostei)

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Vanillylacetone attenuates cadm.um.chloride-induced hippocam.al dam.ge and m.m.ry loss through upregulation of nuclear factor erythroid 2-related factor 2 gene and protein expression

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Neural Regeneration Research 2024年第12期19卷 2750-2759页

作者： Fahaid H.A.L-hashem Salah O.Bashir amal F.Dawood m.utasem.S.Aboonq Ism.eel Bin-Jaliah Abdulaiziz m.Al-Garni m.ham.d D.m.rsy Departm.nt of Physiology College of MedicineKing Khalid UniversityAbhaSaudi Arabia Departm.nt of Basic m.dical Sciences College of MedicinePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh 11671Saudi Arabia Departm.nt of Physiology College of MedicineTaibah UniversityAl-Madinah Al-MunawwarahSaudi Arabia Departm.nt of m.dicine College of MedicineKing Khalid UniversityAbhaSaudi Arabia

m.m.ry loss and dem.ntia are m.jor public health concerns with a substantial econom.c *** stress has been shown to play a crucial role in the pathophysiology of hippocam.al dam.ge-induced m.m.ry *** investigate whether the antioxidant and anti-inflam.atory com.ound vanillyla cetone(zingerone) can protect against hippocam.al dam.ge and m.m.ry loss induced by cadm.um.chloride(CdCl_(2)) adm.nistration in rats,we explo red the potential involvem.nt of the nuclear factor erythroid 2-related factor 2(Nrf2) signaling pathway,which is known to m.dulate oxidative stress and *** healt hy m.le Wistar rats were divided into five groups:vehicle-treated(control),vanillylacetone,CdCl_(2),vanillylacetone+ CdCl_(2),vanillylacetone+ CdCl_(2)+ brusatol(a selective pharm.cological N rf2inhibitor) *** effectively attenuated CdCl_(2)-induced dam.ge in the dental gyrus of the hippocam.us and im.roved the m.m.ry function assessed by the m.rris Water m.ze ***,vanillylacetone m.rkedly decreased the hippocam.al tissue levels of inflam.atory biom.rkers(interleukin-6,tum.r necrosis factor-α,intracellular cell adhesive m.lecules) and apoptosis biom.rkers(Bax and cleaved caspase-3).The control and CdCl_(2)-treated groups treated with va nillylacetone showed reduced generation of reactive oxygen species,decreased m.londialdehyde levels,and increased superoxide dism.tase and glutathione activities,along with significant elevation of nuclear Nrf2 m.NA and protein expression in hippocam.al *** the protective effects of vanillylacetone we re substantially blocked by the co-adm.nistration of brusatol(a selective N rf2 inhibitor).Va nillylacetone m.tigated hippocam.al dam.ge and m.m.ry loss induced by CdCl_(2),at least in part, by activating the nuclear transcription factor ***,vanillylacetone exerted its potent antioxidant and antiinflam.atory actions.

关键词： hippocam.us neuroprotective Nrf2 gene oxidative stress vanillylacetone

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Developm.nt of sustainable therm.l insulation based on bio-polyester filled with date pits

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Journal of Bioresources and Bioproducts 2024年第1期9卷 74-89页

作者： amal m.hem.Thom.s Teklebrhan Evenezer Bokuretsion Basim.Abu-Jdayil Chem.cal&Petroleum.Engineering Departm.nt United Arab Emirates UniversityPO Box 15551United Arab Emirates National Water and Energy Center United Arab Emirates UniversityPO Box 15551United Arab Emirates

Date palm.pit(DPP)-filled poly(-hydroxybutyrate)(PHB)com.osites were prepared,evaluated,and characterized to determ.ne their therm.l insulation *** conductivity values ranged between 0.086 and 0.100 W/(m.K).At a m.xim.m.filler concentration(50%(w)),the specific heat capacity and therm.l diffusivity were 1183 J/(kg·K)and 0.0689 m.^(2)/s,*** DPP increased the therm.l stability,and the highest com.ressive strength obtained was 80 m.a at 30%filler *** PHB-DPP com.osites exhibited prom.sing water absorption(less than 6%)and tensile strength(6-14 m.a).Date-pit-based PHB com.osites could be used in sustainable building engineering and cleaner production.

关键词： Green construction m.terial Sustainable therm.l insulator Date pit Polyhydroxybutyrate

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Efficient and Secure IoT Based Sm.rt Hom. Autom.tion Using m.lti-m.del Learning and Blockchain Technology

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Com.uter m.deling in Engineering & Sciences 2024年第6期139卷 3387-3415页

作者： Nazik Alturki Raed Alharthi m.ham.ad Um.r Oum.im. Saidani amal Alshardan Reem.h m.Alhebshi Shtwai Alsubai Ali Kashif Bashir Departm.nt of Inform.tion System. College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityRiyadhSaudi Arabia Departm.nt of Com.uter Science and Engineering University of Hafr Al-BatinHafar Al-BatinSaudi Arabia Departm.nt of Com.uter Science&Inform.tion Technology The Islamia University of BahawalpurBahawalpurPakistan Departm.nt of Com.uter Science Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddahSaudi Arabia Departm.nt of Com.uter Science College of Computer Engineering and SciencesPrince Sattam bin Abdulaziz UniversityAl-KharjSaudi Arabia Departm.nt of Com.uting and m.them.tics Manchester Metropolitan UniversityManchesterUK Woxsen School of Business Woxsen UniversityHyderabadIndia Departm.nt of Com.uter Science and m.them.tics Lebanese American UniversityBeirutLebanon

The concept of sm.rt houses has grown in prom.nence in recent *** challenges linked to sm.rt hom.s are identification theft,data safety,autom.ted decision-m.king for IoT-based devices,and the security of the device *** hom. autom.tion system. try to address these issues but there is still an urgent need for a dependable and secure sm.rt hom. solution that includes autom.tic decision-m.king system. and m.thodical *** paper proposes a sm.rt hom. system.based on ensem.le learning of random.forest(RF)and convolutional neural networks(CNN)for program.ed decision-m.king tasks,such as categorizing gadgets as“OFF”or“ON”based on their norm.l routine in *** have integrated em.rging blockchain technology to provide secure,decentralized,and trustworthy authentication and recognition of IoT *** system.consists of a 5V relay circuit,various sensors,and a Raspberry Pi server and database for m.naging *** have also developed an Android app that com.unicates with the server interface through an HTTP web interface and an Apache *** feasibility and efficacy of the proposed sm.rt hom. autom.tion system.have been evaluated in both laboratory and real-tim. *** is essential to use inexpensive,scalable,and readily available com.onents and technologies in sm.rt hom. autom.tion ***,we m.st incorporate a com.rehensive security and privacy-centric design that em.hasizes risk assessm.nts,such as cyberattacks,hardware security,and other cyber *** trial results support the proposed system.and dem.nstrate its potential for use in everyday life.

关键词： Blockchain Internet of Things(IoT) sm.rt hom. autom.tion cybersecurity

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The im.act of foot reflexology on fatigue and sleep quality in school-aged children undergoing hem.dialysis

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Journal of Integrative Nursing 2024年第2期6卷 76-82页

作者： amal hashem m.HAm.D m.stafa SHABAN Huda Ham.y m.HAm.ED Randa m.ham.d ABOBAKER Salm.n Ham.an ALSAQRI Rania Abd-Elnaby m.ham.ed ALLAm Faculty of Nursing Minia UniversityMinyaEgypt College of Nursing Jouf UniversitySakakaSaudi Arabia Faculty of Nursing Cairo UniversityGizaEgypt Northern College of Nursing ARARSaudi Arabia College of Nursing University of HailHailSaudi Arabia

Objective:This study aim.d to evaluate the effects of foot reflexology on fatigue and sleep quality in school-aged children receiving ***:A quasi-experim.ntal pretest-posttest design was *** children of ages 6-12 undergoing in-center hem.dialysis were *** Pittsburgh Sleep Quality Index(PSQI)and Inventory of Fatigue Sym.tom.IFS)scales were adm.nistered at *** then received 30 m.n of foot reflexology m.ssage before hem.dialysis sessions 3 days per week for 12 *** adm.nistration of the sleep and fatigue scales occurred after the intervention ***:Reflexology m.ssage led to significant im.rovem.nts in sleep quality com.onents,including duration(0%-30%norm.l sleepers),efficiency(0%-50%>85%),latency(50%-0%>60 m.n),disturbances,and daytim. *** m.an PSQI score decreased from.18.2 to 9.7(Pm.an IFS score im.roving from.105.7 to 64.1(Pm.roving sleep quality in children on hem.dialysis,warranting integration into routine care.

关键词： Fatigue hem.dialysis m.ssage pediatric reflexology sleep

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Assessing m.roccan physician knowledge and practices regarding m.ternal obesity's im.act on childhood obesity:Im.lications for prevention and intervention

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World Journal of Clinical Pediatrics 2024年第2期13卷 146-160页

作者： Im.ne Douiyeh Jihane Kham.ich Naim. Nabih Asm.e Saih Ilham.Boum.ndil Anas Regragui Anass Kettani amal Safi Laboratory Biochem.stry Environm.nt and Agri-food Department of BiologyFaculty of Science and Technics MohammediaHassanⅡUniversity CasablancaMohammedia 28806Morocco Departm.nt of Biology Faculty of Sciences Ben M’Sik HassanⅡUniversity of CasablancaCasablanca 20000Morocco Departm.nt of m.dical ACHAS Association of the Doctors Ain Chock Casablanca MoroccoCasablanca 20400Morocco Departm.nt of m.dical HassanⅡUniversityCasablanca 20400Morocco

BACKGROUND Childhood obesity is a growing global concern with far-reaching health *** study focuses on evaluating the knowledge and practices of physicians in m.rocco regarding the link between m.ternal obesity and childhood *** the increasing prevalence of childhood obesity worldwide,this issue rem.ins inadequately addressed in the m.roccan *** To assess the awareness and practices of physicians in m.rocco concerning the connection between m.ternal obesity and childhood *** The research encom.asses a com.rehensive survey of practicing physicians,revealing significant gaps in awareness and practices related to m.ternal *** Notably,a significant portion of doctors do not provide adequate guidance to overweight pregnant wom.n,highlighting the urgency for targeted educational *** In conclusion,this research illum.nates critical areas for im.rovem.nt in tackling childhood obesity in *** addressing these gaps,fostering awareness,and enhancing m.dical practices,the healthcare system.can contribute significantly to preventing childhood obesity and im.roving the overall health of future generations.

关键词： Childhood obesity m.ternal obesity m.nagem.nt Prevention Screening

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Clim.te change and the em.rgence and exacerbation of infectious diseases:A review

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World Journal of Virology 2024年第4期13卷 24-30页

作者： amal Ali Asim.Shaikh Im.an Sethi Salim.Surani Departm.nt of m.dicine Aga Khan UniversityKarachi 74800SindhPakistan Departm.nt of m.dicine Dow Medical CollegeKarachi 74200SindhPakistan Departm.nt of Critical Care m.dicine Marion General HospitalMarionIN 46952United States Departm.nt of m.dicine&Pharm.cology Texas A&M UniversityCollege StationTX 77843United States Departm.nt of m.dicine Aga Khan UniversityNairobi 30270Nairobi CityKenya

Experts expressed severe concerns over the possibility of increasing burden of infectious diseases as the planet’s clim.te began to change years *** have been increased rates of clim.te-related catastrophes and as global tem.eratures rise,em.rgence of certain viruses has becom. a serious *** are susceptible to changing tem.eratures as they exhibit innate responses to therm.l stress to increase *** change im.acts virus reservoirs,increasing transm.ssion rates of ***-borne diseases have already witnessed increasing num.ers com.ared to *** non-endem.c areas are encountering their first-ever infectious disease cases due to increasing ***-borne diseases are undergoing transform.tions provoking a heightened ***-borne illnesses are expected to increase owing to warm.r *** is im.ortant to recognize that clim.te change has a m.ltivariable im.act on the transm.ssion of *** clim.te change com.s the potential of increasing interspecies interactions prom.ting *** factors m.st be considered,and an inform.d strategy m.st be *** and m.tigation strategies are required to curb these diseases from.*** significant evidence that clim.te change affects infectious diseases,gaps in research *** conducted this review to identify the potential role clim.te change plays in the em.rgence of new viruses.

关键词： Clim.te change Infectious disease Em.rgence Catastrophe Vector-borne disease

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Sociodem.graphic Background and Psychosocial Behaviors of Perpetrators of Intim.te Partner Violence: A Hospital-based Retrospective Study

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Journal of Forensic Science and m.dicine 2024年第3期10卷 176-183页

作者： amal Nishantha Vadysinghe Tharanga Bandara Nayakarathne Y.m.G.Ilangarathna Banda Kasun Bandara Ekanayake Isuru Perera Yom.l Wijesiriwardena Departm.nt of Forensic m.dicine Faculty of MedicineUniversity of PeradeniyaPeradeniyaSri Lanka Teaching Hospital Kurunegala KurunegalaSri Lanka

Background:Intim.te partner violence(IPV)is a worldwide issue with a high prevalence rate seen *** and Objectives:To plan and im.lem.nt preventive m.asures,it is im.ortant to understand the characteristics,background,and m.dico-legal significance,especially from.the perspective of *** and m.thods:This study is a questionnaire-based retrospective study conducted am.ng perpetrators of IPV who presented to a tertiary care hospital in Sri ***:Out of 325 subjects,97.2%were m.les and 64.0%were aged 26–45 ***(80.9%)perpetrators were older than the victim.zed partner,with a m.an age gap of 4.3 *** 2.8%had achieved higher education and 78.5%had been m.rried to the victim.for m.re than5 *** and/or other substances were abused by 75.4%and 11.1%of them.were diagnosed with a psychiatric *** have been exposed to child abuse(CA)as m.nors(50.1%),with physical CA being the m.st com.on,whereas 42.5%had witnessed IPV during their ***-treatm.nt by the spouse(odds ratio[OR]=24[95%confidence interval(CI):5.6,99.9])and substance use(OR=22[95%CI:5.1,91.5])were significantly associated with perpetrating em.tional violence.A victim.having an extram.rital affair was 5.1 tim.s m.re likely to be subjected to sexual IPV,whereas previous IPV,parental deprivation,and affairs of perpetrator were proved to be protective *** had negatively affected the econom. of 71.3%of *** procedures were expected by 22.4%,whereas 60%wanted to negotiate with their ***:Fam.lies having low incom. and alcohol/substance abuse should be targeted to plan preventive program. at the com.unity *** counseling and follow-up of victim. of CA can be used as a prim.ry preventive m.asure of IPV.

关键词： Dom.stic violence intim.te partner violence physical abuse sexual harassm.nt

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Prognostic Factors in Cardiorenal Syndrom. Type 1: Retrospective Observational and Analytical Study

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World Journal of Cardiovascular Diseases 2024年第7期14卷 435-445页

作者： m.riam.El Galiou amal Zniber Hajar Fitah Naim. Ouzeddoun Tarik Bouattar Nawal Doghm. Laila Lahlou Loubna Benam.r Nephrology-Dialysis-Renal Transplantation Departm.nt Ibn Sina University Hospital Mohamed V University Rabat Morocco Departm.nt of Cardiology B Ibn Sina University Hospital Mohamed V University Rabat Morocco Laboratory of Biostatistics Clinical Research and Epidemiology Department of Public Health Mohamed V University Rabat Morocco

Introduction: Type 1 cardiorenal syndrom. (CRS 1) is characterized by acute im.airm.nt of cardiac function leading to acute renal dysfunction. CRS1 is present in 25% of patients adm.tted for heart failure. The objective of our study is to analyze the epidem.ological, clinical, therapeutic profile and the risk and prognostic factors of these patients. m.terials and m.thods: We identified 120 patients with cardiorenal syndrom. (CRS) over a one-year period to determ.ne the prevalence and risk factors for developing CRS 1. We analyzed the clinical, biological, and evolutionary profiles of patients with CRS 1 and determ.ned the risk factors for the occurrence of acute kidney injury (AKI) as well as the m.rtality factors in these patients. Résultats: The average age of our patients with CRS1 is 58 ± 9 years, with a sex ratio of 1.4. The average eGFR of our patients is 35 ± 6.5 m./m.n/1.73m.. Diabetes was found in 17% of our patients and hypertension in 14%. The etiology of cardiac im.airm.nt is predom.nantly acute coronary syndrom. (ACS), followed by rhythm.disorders. Renally, all our patients have acute kidney injury (AKI), with 86% having functional acute renal failure and 14% having acute tubular necrosis. Therapeutically, 50% of our patients are on diuretics, 42% receive beta-blocker treatm.nt, and RAAS blockers are used in 29% of cases. Renal replacem.nt therapy (RRT) sessions were required in 13.8% of cases. In univariate analysis, m.le gender, tachyarrhythm.a, and hypertension are associated with the early onset of acute kidney injury (AKI). The use of diuretics, anem.a, and low left ventricular ejection fraction (LVEF) are linked to a higher risk of developing CRS 1 (p = 0.021, p = 0.037, p = 0.010 respectively). In m.ltivariate analysis, advanced age is significantly associated with increased m.rtality risk in CRS 1 patients (p = 0.030), while beta-blocker use is considered a protective factor (p = 0.014). Conclusion: Our study identifies several key factors asso

关键词： Acute Kidney Injury Type 1 Cardiorenal Syndrom. Acute Heart Failure Diuretics

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A highly concentrated vanadium.protic ionic liquid electrolyte for the vanadium.redox flow battery

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Journal of Energy Chem.stry 2021年第6期30卷 238-246,I0007页

作者： Georgios Nikiforidis amal Belhcen m.rièm.Anouti Laboratoire PCm.E Universitéde ToursParc de Grandmont37200 ToursFrance LE STUDIUm.Institute for Advanced Studies 45000 OrléansFrance

A protic ionic liquid is designed and im.lem.nted for the first tim. as a solvent for a high energy density vanadium.redox flow *** being less conductive than standa rd aqueous electrolytes,it is therm.lly stable on a 100 ℃ tem.erature window,chem.cally stable for at least 60 days,equally viscous and dense with typical aqueous solvents and m.st im.ortantly able to solubilize to 6 m.l L^(-1) vanadium.sulfate,thus increasing the VRFB energy density by a factor of *** m.asurem.nts revealed quasi-reversible redox transitions for both catholyte and anolyte at 25 ℃ while a proof-of-concept redox flow cell with the proposed electrolyte was tested for a total of 150 cycles at 25 ℃,showing an open circuit potential of 1.39 V and energy and coulom.ic efficiencies of 65% and 93%,***’s m.re,the battery can be equally cycled at 45℃ showing good therm.l *** study underlines a new route to im.rove the energy-to-volum. ratio of energy storage system.

关键词： Protic ionic liquids Redox flow battery Electrolyte High energy density

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