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Bithalamic Ischemic Stroke in Sickle Cell Patient at the Kamenge University hospital in Burundi: Case Report

Open Journal of Medical Imaging 2024年第2期14卷 72-78页

作者： Sébastien Manirakiza Daniel Nduwayo Patrice Barasukana Chantal Murekatete Jean Bosco Bizimana Alice Ndayishimiye léopold Nzisabira hélène Bukuru Department of Radiology Kamenge University Hospital Center University of Burundi Bujumbura Burundi Department of Internal Medicine Neurology Kamenge University Hospital Center University of Burundi Bujumbura Burundi Department of Surgery Neurosurgery Kamenge University Hospital Center University of Burundi Bujumbura Burundi Department of Pediatrics Kamenge University Hospital Center University of Burundi Bujumbura Burundi

Aim: To describe the clinical and radiological diagnostic for a sickle cell patient who got a bithalamic vasculature accident. Observation: This was a 4-year-old female child admitted to the pediatric ward for convulsive seizures in a feverish context. The physical examination did not find signs of meningeal irritation. The effective workup including thick gout, lumbar puncture, complete blood count, and C reactive protein was normal. An electrocencephalogram was not performed due to lack of availability of the device. Based on clinical data and the fact that Burundi is an area of high malaria prevalence, antimalarial and anticonvulsant treatment has been started. An alteration of consciousness (the Glasgow score of 7) had motivated a CT scan. Bithalamic hypodensities in favor of a vascular accident have been demonstrated. Etiological investigation revealed homozygous sickle cell disease ss during hemoglobin electrophoresis. The final evolution has been characterized by a return to normal consciousness. Conclusion: The complexity of the clinical picture following occlusion of Percherons artery makes it difficult to diagnose. Sickle cell disease may favour the occurrence of ischaemic lesions. Cerebral imaging enables the diagnosis to be made with certainty and avoids delays in treatment.

关键词： Stroke Bithalamic Infarction Sickel Cell Percheron Artery

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An efficient descriptor model for designing materials for solar cells

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npj Computational Materials 2015年第1期1卷 38-46页

作者： Fahhad h.alharbi Sergey N Rashkeev Fedwa El-Mellouhi hans P lüthi Nouar Tabet Sabre Kais College of Science and Engineering Hamad Bin Khalifa UniversityDohaQatar Qatar Environment and Energy research Institute(QEERI) Hamad Bin Khalifa UniversityDohaQatar Department of Chemistry and Applied Bioscience ETH ZurichZurichSwitzerland

An efficient descriptor model for fast screening of potential materials for solar cell applications is *** works for both excitonic and non-excitonic solar cells materials,and in addition to the energy gap it includes the absorption spectrum(α(E))of the *** charge transport properties of the explored materials are modelled using the characteristic diffusion length(ld)determined for the respective fam.ly of *** presented model surpasses the widely used Scharber model developed for bulk heterojunction solar *** published experimental data,we show that the presented model is more accurate in predicting the achievable *** model both excitonic and non-excitonic systems,two different sets of parameters are used to account for the different modes of *** analysis of the presented descriptor model clearly shows the benefit of includingα(E)and ld in view of improved screening results.

关键词： material. designing model

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Development and Optimization of Universal Bone Conduction hearing Spectacles

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International Journal of Otolaryngology and head & Neck Surgery 2024年第5期13卷 344-358页

作者： Johannes Burkart Mona Kirstin Fehling Saadu Adamu Raúl Pérez Ramos Daniel häussler Department of Otorhinolaryngology Head and Neck Surgery University Hospital Mannheim Mannheim Germany National Ear Care Centre Kaduna Nigeria School of Advanced Education Research and Accreditation University Isabel I Castelln de la Plana Spain

Background: Non-implantable bone anchored hearing devices (BChDs) are utilized for patients with conductive or mixed hearing loss who are unsuitable for conventional hearing aids or have unresolved middle ear issues. These devices can be surgically implanted or attached using adhesive plates, dental sticks, elastic headbands, or bone conduction spectacles. Optimal fitting of bone conduction spectacles requires appropriate frame selection and contact pressure in the temporal and mastoid areas. The ANSI S3.6 and DIN EN ISO 389-3 standards recommend a contact area of approximately 1.75 cm2 and a maximum force of 5.4 N for effective sound transmission and comfort. Methods: This study aimed to evaluate the technical fit and mechanical stability of universal bone conduction hearing spectacles compared to established systems. A Sen-Pressure 02 thin-film sensor connected to an Arduino Uno R3 board measured contact force in the temporal and mastoid areas. Several BChDs were tested, including the Bruckhoff la belle BC D50/70, Radioear B71 headset, Radioear B71 elastic headband, Cochlear Baha SoundArc M, and Cochlear Baha elastic headband, on a PVC artificial head, with data analyzed using ANOVA and lSD post hoc tests. Results: The la belle BC D50/70 spectacles showed comparable contact force to established BChDs, ensuring adequate sound transmission and comfort. Significant differences were observed between the systems, with the Radioear B71 headset exhibiting the highest forces. The la belle BC D50/70 had similar forces to the Radioear B71 elastic headband. Conclusion: The la belle BC D50/70 universal bone conduction hearing spectacles are a technically equivalent alternative to established BChDs, maintaining pressure below 5.4 N. Future research should explore the impact of different contact forces on performance and comfort, and the integration of force control in modified spectacles. This study indicates that the la belle BC D50/70 is a viable alternative that meets audio

关键词： Bone Conduction hearing Devices (BChD) Universal Bone Conduction hearing Spec-Tacles Non-Implantable hearing Aids Contact Pressure Optimization

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Validation of the TOPAS Monte-Carlo Code of the Off-Field Dose of a 6 MV Synergy linac

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Journal of Biosciences and Medicines 2024年第7期12卷 38-54页

作者： Kodjo Joel Fabrice N’Guessan Ibrahima Sakho Bogbé D. l. h. Gogon Department of Physics and Chemistry Faculty of Sciences and Technology Iba Der Thiam University of This This Senegal International Cancer Center of Dakar Dakar Senegal Department of Physics Faculty of Sciences and Technology Flix Houphouet Boigny University of Abidjan Abidjan Cte dIvoire

The risk of radiation-induced second cancer and the late tissue loss due to Off-field doses in radiotherapy remain a serious concern. Monte Carlo (MC) simulation is currently one of the most accurate methods for calculating these doses. MC simulation model based on the Particle Simulation Tool (TOPAS) has been developed to simulate the off-field dose of an Elekta Synergy linear accelerator (linac) emitting 6 MV photons. Measurements were taken in a water phantom using an ionization chamber to validate this model. The Percentage Depth Dose (PDD) at the depth of 0.0, 5.0, 10.0 and 15.0 cm from the beam axis for a 10 × 10 cm2 field size was measured and simulated. Off-field dose profiles at the depth of 1.5 (dmax), 5.0 and 10.0 cm for field sizes of 5 × 5, 10 × 10, 15 × 15, and 20 × 20 cm2 respectively were measured and simulated. Comparison of measured and simulated off-field dose values showed a good agreement. The average gamma passing rate of the PDDs and profiles curves for off-field doses were 87.5% and 98.11% respectively. The local dose difference based on the PDD curve between the measured and simulated was less than 6.0 % for all locations. For all field size considered in this study, the average difference between profile curves for off-field dose measured and simulated was 9.1%. PDDs and Profiles curves for off-field dose simulation uncertainties were less than 2.0% and 1.0% respectively. TOPAS-MC simulation model developed is a good representation of our 6 MV linac Elekta Synergy for assessing off-field dose, which would be the primary cause of some secondary cancers.

关键词： Radiotherapy Off-Field Dose Secondary Cancer TOPAS-MC Simulation Dosimetry

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Sustainability assessment of solar drying systems:a comparative life-cycle analysis of phase-change material-based *** solar dryers

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Clean Energy 2024年第4期8卷 183-196页

作者： Nakum Divyangkumar Kirtika Sharma N.l.Panwar Gande Saichandhu Department of Renewable Energy Engineering Maharana Pratap University of Agriculture and TechnologyUdaipur(Rajasthan)313001India Environmental Management Jawaharlal Nehru University TechnologyHyderabadIndia

Solar drying systems are becoming a popular alternative to traditional energy-based drying systems for agricultural products due to their effectiveness and reduced fuel *** the efficiency of solar drying systems has been thoroughly investigated,their sustainability has not been studied *** study aims to fill that gap by conducting a life-cycle assessment of two new solar drying systems built in Udaipur,Rajasthan,*** environmental implications of an innovative cylindrical solar-assisted drying system and a phase-change material-based solar drying system were evaluated using cradle-to-gate life-cycle *** study uses the ReCiPe 2016 endpoints(h)technique to calculate various aspects such as midpoint,endpoint,single score,normalization result,and network diagram for phase-change material-based solar drying and cylindrical solar-assisted *** show that phase-change material-based solar drying has an average of 40%more impact on the environment than cylindrical solar-assisted drying,with a high impact found in human non-carcinogenic toxicity,mainly due to the production of phase-change ma***,cylindrical solar-assisted drying system crossover phase-change material based solar drying in terms of its impact on human carcinogenic toxicity and fossil resource *** contribution to global warming of phase-change material-based solar drying is 13.7%more than that of cylindrical solar-assisted *** endpoint characterization indicates that phase-change material-based solar drying exceeds in terms of human health(40%)and ecosystem(37.04%),whereas cylindrical solar-assisted drying surpasses phase-change material-based solar drying in terms of impacts on resources,at 14%.The early drying in phase-change material-based solar drying makes up for its higher impact than that in cylindrical solar-assisted drying,which takes 3 hours longer to *** study offers guidance and methods for making the best choice of

关键词： solar drying cylindrical hybrid solar dryer PCM-based solar dryer life-cycle assessment ReCiPe method impact assessment

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high-efficiency Carbonation Modification Methods of Recycled Coarse Aggregates

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Journal of Wuhan University of Technology(Materials Science) 2024年第2期39卷 386-398页

作者：张美香 YANG Xiaolin 丁亚红 SUN Bo ZhANG Xianggang lÜXiuwen Department of Civil Engineering Henan Polytechnic UniversityJiaozuo 454150China College of Architectural Engineering Xinyu UniversityXinyu 336500China

To solve the problem of only surface carbonation and realize high-efficiency carbonation of recycled coarse aggregate,the method of carbonated recycled coarse aggregate with nano materials pre-soaking was first put *** carbonation effect of modified recycled coarse aggregate with three different carbonation methods was evaluated,and water absorption,apparent density and crush index of modified recycled coarse aggregate were *** with XRD,SEM,and MIP microscopic analysis,the high-efficiency carbonation strengthening mechanism of modified recycled coarse aggregate was *** experimental results show that,compared with the non-carbonated recycled coarse aggregate,the physical and microscopic properties of carbonated recycled coarse aggregate are *** method of carbonation with nano-SiO_(2) pre-soaking can realize the high-efficiency carbonation of recycled coarse aggregate,for modified recycled coarse aggregate with the method,water absorption is reduced by 23.03%,porosity is reduced by 44.06%,and the average pore diameter is 21.82 *** high-efficiency carbonation strengthening mechanism show that the pre-socked nano-SiO_(2) is bound to the hydration product Ca(Oh)_(2) of the old mortar with nano-scale C-S-h,which can improve the CO_(2) absorption rate,accelerate the carbonation reaction,generate more stable CaCO_(3) and nano-scale silica gel,and bond to the dense three-dimensional network structure to realize the bidirectional enhancement of nano-materials and pressurized *** is concluded that the method of carbonation with nano-SiO_(2) pre-soaking is a novel high-efficiency carbonation modification of recycled coarse aggregate.

关键词： recycled coarse aggregate pressurized carbonation high-efficiency carbonation nano-SiO2 strengthening mechanism

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Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina hromada Patrick heimel Markus Kerbl lászlóGál Sylvia Nürnberger Barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.heinzel Antal Nógrádi Andreas h.Teuschl-Woller David hercher Department life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). however, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

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am.loid-beta and tau protein beyond Alzheimer's disease

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Neural Regeneration Research 2024年第6期19卷 1262-1276页

作者： Morteza Abyadeh Vivek Gupta Joao A.Paulo Arezoo Gohari Mahmoudabad Sina Shadfar Shahab Mirshahvaladi Veer Gupta Christine T.O.Nguyen David I.Finkelstein Yuyi You Paul A.haynes Ghasem h.Salekdeh Stuart l.Graham Mehdi Mirzaei ProGene Technologies Pty ltd. SydneyNSWAustralia Department of Clinical Medicine Faculty of MedicineHealth and Human SciencesMacquarie Medical SchoolMacquarie UniversityMacquarie ParkNorth RydeSydneyNSWAustralia Department of Cell Biology Harvard Medical SchoolBostonMAUSA School of Medicine Deakin UniversityGeelongVICAustralia Department of Optometry and Vision Sciences School of Health SciencesFaculty of Medicine Dentistry and Health SciencesUniversity of MelbourneParkvilleVICAustralia The Florey Institute of Neuroscience and Mental health The University of MelbourneParkvilleVICAustralia School of Natural Sciences Macquarie UniversityMacquarie ParkNSWAustralia

The aggregation of am.loid-beta peptide and tau protein dysregulation are implicated to play key roles in Alzheimer's disease pathogenesis and are considered the main pathological hallmarks of this devastating ***,these two proteins are produced and expressed within the normal human ***,under pathological conditions,abnormal expression,posttranslational modifications,conformational changes,and truncation can make these proteins prone to aggregation,triggering specific disease-related *** studies have indicated associations between aberrant behavior of am.loid-beta and tau proteins and various neurological diseases,such as Alzheimer's disease,Parkinson's disease,and amyotrophic lateral sclerosis,as well as retinal neurodegenerative diseases like Glaucoma and age-related macular ***,these proteins have been linked to cardiovascular disease,cancer,traumatic brain injury,and diabetes,which are all leading causes of morbidity and *** this comprehensive review,we provide an overview of the connections between am.loid-beta and tau proteins and a spectrum of disorders.

关键词： am.loid-beta cancer cardiovascular diseases diabetes neurodegeneration Tau traumatic brain injury

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Racial and Ethnic Differences in Orthorexia Nervosa Symptomatology and Other Disordered Eating

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Open Journal of Psychiatry 2024年第4期14卷 287-299页

作者： Dilan h. Arreguin Kendria S. Shields-Rhodes Melissa l. harel Crystal D. Oberle Department of Psychology Texas State University San Marcos TX USA

While some research has explored racial and ethnic differences in disordered eating, this study may be the first to examine these differences in orthorexia nervosa, involving obsessive-compulsive thoughts and behaviors concerning healthy eating, which negatively impact one’s life. Adult participants, recruited from college courses and social media, completed an online survey with the Orthorexia Nervosa Inventory (ONI) and the Eating Attitudes Test-26 (EAT-26). Regarding racial and ethnic background, 743 were White, 249 were hispanic, 87 were Black, 61 were Asian or Pacific Islander, and 110 were biracial/multiracial. A MANCOVA revealed that the racial and ethnic groups did not differ on the ONI subscales assessing orthorexic behaviors, impairments, and emotions, after accounting for gender, BMI, and EAT-26 total scores that were covariates. In contrast, a second MANCOVA did reveal group differences on the EAT-26 subscales, after accounting for gender, BMI, and ONI total scores that were covariates. Black participants scored significantly lower than the other racial and ethnic groups on the subscale assessing dieting behaviors characteristic of anorexia nervosa, and the subscale assessing binge-eating and purging behaviors characteristic of bulimia nervosa. Further, hispanic participants scored significantly lower than White participants on the latter subscale. These findings suggest that while orthorexic symptomatology does not differ based on race and ethnicity, a Black race and hispanic ethnicity may be protective factors against disordered eating, perhaps related either to cultural norms concerning body image or to the resiliency and social support among the Black and hispanic communities.

关键词： Race Ethnicity Orthorexia Disordered Eating

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am.litude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban h.-R.Bao V.Batozskaya K.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann h.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.l.Chang G.R.Che G.Chelkov C.Chen C.h.Chen Chao Chen G.Chen h.S.Chen M.l.Chen S.J.Chen S.l.Chen S.M.Chen T.Chen X.R.Chen X.T.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui h.l.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng J.h.Feng Y.T.Feng K.Fischer M.Fritsch C.D.Fu J.l.Fu Y.W.Fu h.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge Z.W.Ge C.Geng E.M.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong l.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Z.h.Duan P.Egorov Y.h.Fan J.Fang JA.Gilman K.Goetzen l.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.h.Gu Y.T.Gu C.Y.Guan Z.l.Guan A.Q.Guo l.B.Guo M.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.l.han T.T.han X.Q.hao F.A.harris K.K.he K.l.he F.h.heinsius C.h.heinz Y.K.heng C.herold T.holtmann P.C.hong G.Y.hou X.T.hou Y.R.hou Z.l.hou B.Y.hu h.M.hu J.F.hu T.hu Y.hu G.S.huang K.X.huang l.Q.huang X.T.huang Y.P.huang T.hussain F.h\"olzken N.h\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.h.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.l.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang h.B.Jiang P.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki X.l.Kang X.S.Kang M.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf M.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.lane P.larin l.lavezzi T.T.lei Z.h.lei h.leithoff M.lellmann T.lenz C.li C.li C.h.li Cheng li D.M.li F.li G.li h.li h.B.li h.J.li h.N.li hui li J.R.li J.S.li K.li l.J.li l.K.li lei li M.h.li P.R.li Q.M.li Q.X.li R.li S.X.li T.li W.D.li W.G.li X.li X.h.li X.l.li X.Y.li Y Institute of high Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China hangzhou Normal University Hangzhou 310036China hebei University Baoding 071002China helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University Kaifeng 475004China henan University of Science and Technology Luoyang 471003China henan University of Technology Zhengzhou 450001China huangshan College Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint am.litude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained am.litude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** am.litude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays am.litude analysis CP-even fraction

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