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Conge.ital Me.oblastic Ne.hroma: A Case.Re.ort

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Ope. Journal of Pe.iatrics 2024年第5期14卷 834-840页

作者： e. A. Alinnor O. C. Ugwa I. O. Nnamani De.artme.t of Pae.iatrics University of Port Harcourt Teaching Hospital Port Harcourt Nigeria De.artme.t of Anatomical Pathology University of Port Harcourt Teaching Hospital Port Harcourt Nigeria

Background: Conge.ital Me.oblastic Ne.hroma (CMN) is a me.e.chymal re.al tumour of e.rly life. With a me.ian diagnosis of two months and ove. 90% of case. occurring within the.first ye.r of life. it is the.most pre.ale.t non-Wilms’ re.al tumour. e.e. though imaging can be.use. as a diagnosing tool, it is fre.ue.tly ide.tifie. in the.ne.natal pe.iod whe. the.baby has an abdominal mass. The.e.are.thre. diffe.e.t histologic type.: mixe., ce.lular, and classic. Radical ne.hre.tomy is the.usual mode.of tre.tme.t, though adjuvant che.othe.apy may be.ne.e.sary for the.ce.lular type. which may be.aggre.sive. Case.pre.e.tation: We.re.ort on a case.of a 2-day-old te.m male.ne.nate.born to a 27-ye.r-old mothe. through spontane.us ve.te. de.ive.y (SVD). He.pre.e.te. with a right-side. abdominal mass from birth. An abdominal ultrasound scan re.e.le. a huge. we.l-circumscribe. he.e.oge.e.us soft tissue.mass in the.right he.i-abdome. e.te.ding to the.le.t side. me.suring 10.2 cm by 8.0 cm. He.unde.we.t a right radical ne.hre.tomy with a tumour we.ght of 450 g and a size.of 18 cm × 15 cm × 6 cm. Histopathological diagnosis was Conge.ital Me.oblastic Ne.hroma (ce.lular type. Stage.1. Conclusion: Any infant with a re.al tumour should be.e.aluate. for conge.ital me.oblastic ne.hroma. De.aile. inve.tigation and comple.e.re.e.tion are.fundame.tal for e.suring an e.ce.le.t outcome.

关键词： Conge.ital Me.oblastic Ne.hroma Ne.hre.tomy Ne.nate

Le.rning the.optimal powe. flow:e.vironme.t de.ign matte.s

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e.e.gy and AI 2024年第3期17卷 432-443页

作者： Thomas Wolgast Astrid Nie.e Carl von Ossie.zky Unive.sität Olde.burg Department of Computing ScienceDigitalized Energy SystemsAmmerländer Heerstraße 114-118Oldenburg26129Germany

To solve.the.optimal powe. flow(OPF)proble.,re.nforce.e.t le.rning(RL)e.e.ge. as a promising ne. ***,the.RL-OPF lite.ature.is strongly divide. re.arding the.e.act formulation of the.OPF proble. as an RL *** this work,we.colle.t and imple.e.t dive.se.e.vironme.t de.ign de.isions from the.lite.ature.re.arding training data,obse.vation space.e.isode.de.inition,and re.ard function *** an e.pe.ime.tal analysis,we.show the.significant impact of the.e.e.vironme.t de.ign options on RL-OPF training ***,we.de.ive.some.first re.omme.dations re.arding the.choice.of the.e.de.ign *** cre.te. e.vironme.t frame.ork is fully ope.-source.and can se.ve.as a be.chmark for future.re.e.rch in the.RL-OPF fie.d.

关键词： Re.nforce.e.t le.rning Optimal powe. flow e.vironme.t de.ign e.onomic Dispatch Voltage.control Re.ctive.powe. marke.

Proje.te. Change. in e.tre.e.e.e.t Indice. for Alaska

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Atmosphe.ic and Climate.Scie.ce. 2024年第2期14卷 191-209页

作者： John e. Walsh Kyle.Re.illa Norman Shippe. Lukas Che.ng David Bige.ow Ronni Wilcock Inte.national Arctic Re.e.rch Ce.te. University of Alaska Fairbanks Fairbanks USA Stante. Ottawa Canada Stante. Montreal Canada Stante. Calgary Canada Two Be.rs e.vironme.tal Consulting Anchorage USA

As climate.has warme. in re.e.t de.ade., Alaska has e.pe.ie.ce. a varie.y of high-impact e.tre.e.e.e.ts that include.he.t wave., wildfire., coastal storms and fre.zing rain. Be.ause.the.warming is proje.te. to continue. it is e.se.tial to conside. future.change. whe. planning adaptation actions and building re.ilie.ce. In this study, we.synthe.ize.information on future.change. in e.tre.e.e.e.ts in Alaska from an e.se.ble.of re.ional climate.mode. simulations pe.forme. as part of Arctic-CORDe. (Coordinate. Re.ional Climate.Downscaling e.pe.ime.t). A se. of 13 e.tre.e.e.e.t indice., base. on those.de.e.ope. by the.World Climate.Re.e.rch Programme.s e.pe.t Te.0} on Climate.Change.De.e.tion and Indice. (e.CCDI), are.e.aluate. from the.Arctic-CORDe. output for Alaska. Of the.13 indice., six pe.tain to te.pe.ature. five.to total pre.ipitation, one.to wind and one.to snow. The.re.ults for locations in se.e. diffe.e.t climate.zone. of Alaska include.large.incre.se. (5˚C - 10˚C) in the.te.pe.ature.thre.holds for the.five.hotte.t and colde.t days of the.ye.r, and large.incre.se. in warm spe.l duration and de.re.se. in cold spe.l duration. Change. in the.cold day te.pe.ature.thre.hold are.ge.e.ally large. than the.change. in the.hot day te.pe.ature.thre.hold, consiste.t with the.proje.tions of a stronge. warming in winte. than in summe. in Alaska ye.rly maximum 1-day and 5-day pre.ipitation amounts as we.l as the.ye.rly numbe. of conse.utive.we. days are.proje.te. to incre.se.at all locations. The.indice. for he.vy snow days and high-wind days show mixe. change., although the.re.ults indicate.incre.se. in he.vy snow days at the.more.northe.n locations and incre.se. in windy days at coastal locations. The.change. in the.e.tre.e.e.e.t indice. continue.through 2100 unde. the.highe.-e.ission (RCP 8.5) e.ission sce.ario, while.the.change. ge.e.ally stabilize.unde. the.lowe.-e.ission (RCP 4.5) sce.ario. .

关键词： e.tre.e.e.e.ts Te.pe.ature Pre.ipitation Alaska Climate

Inte.rate. Zoology calls for pape.s:spe.ial issue.on wildlife.dise.se. and parasitology

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Inte.rative.Zoology 2024年第3期19卷 424-425页

作者： Nubia e.MATTA We.hua XIONG De.artme.t of Biology Universidad Nacional de ColombiaBogotaColombia Inte.national Socie.y of Zoological Scie.ce. BeijingChina Institute.of Zoology Chinese Academy of SciencesBeijingChina

The.VI Inte.national Confe.e.ce.on Malaria and Othe. Blood Parasite. of Wildlife.and the.III Inte.national Symposium of the.Wildlife.Dise.se. Re.e.rch Ne.work are.sche.ule. to be.he.d in Me.e.lín,Colombia,from Nove.be. 26 to 30 of 2024(https://***/lLW79).It will be.hoste. by the.Unive.sity of Antioquia’s De.artme.t of Biology and the.Unive.sidad Nacional de.Colombia De.artme.t of Biology.

关键词： Blood Malaria dise.se.

Optimization of Random Fe.ture.Me.hod in the.High-Pre.ision Re.ime

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Communications on Applie. Mathe.atics and Computation 2024年第2期6卷 1490-1517页

作者： Jingrun Che. We.nan e.Yife. Sun School of Mathe.atical Scie.ce. and Suzhou Institute.for Advance. Re.e.rch Suzhou 215006JiangsuChina Unive.sity of Scie.ce.and Te.hnology of China Hefei 230026AnhuiChina Ce.te. for Machine.Le.rning Re.e.rch and School of Mathe.atical Scie.ce. Peking UniversityBeijing 100871China AI for Scie.ce.Institute Beijing 100084China School of Mathe.atical Scie.ce. Soochow UniversitySuzhou 215006JiangsuChina

Machine.le.rning has be.n wide.y use. for solving partial diffe.e.tial e.uations(PDe.)in re.e.t ye.rs,among which the.random fe.ture.me.hod(RFM)e.hibits spe.tral accuracy and can compe.e.with traditional solve.s in te.ms of both accuracy and ***,the.optimization proble. in the.RFM is more.difficult to solve.than those.that arise.in traditional *** the.broade. machine.le.rning re.e.rch,which fre.ue.tly targe.s tasks within the.low-pre.ision re.ime.our study focuse. on the.high-pre.ision re.ime.crucial for solving *** this work,we.study this proble. from the.following aspe.ts:(i)we.analyze.the.coe.fcie.t matrix that arise. in the.RFM by studying the.distribution of singular value.;(ii)we.inve.tigate.whe.he. the.continuous training cause. the.ove.fitting issue.(ii)we.te.t dire.t and ite.ative.me.hods as we.l as randomize. me.hods for solving the.optimization *** on the.e.re.ults,we.find that dire.t me.hods are.supe.ior to othe. me.hods if me.ory is not an issue.while.ite.ative.me.hods typically have.low accuracy and can be.improve. by pre.onditioning to some.e.te.t.

关键词： Random fe.ture.me.hod(RFM) Partial diffe.e.tial e.uation(PDe. Le.st-square. proble. Dire.t me.hod Ite.ative.me.hod

Olfactory immune.re.ponse.to SARS-CoV-2

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Ce.lular & Mole.ular Immunology 2024年第2期21卷 134-143页

作者： Se.astian A.We.lford e.Ashle. Mose.an De.artme.t of Inte.rative.Immunobiology Duke University School of MedicineDurhamNCUSA

Nume.ous pathoge.s can infe.t the.olfactory tract,ye. the.pande.ic cause. by SARS-CoV-2 has strongly e.phasize. the.importance.of the.olfactory mucosa as an immune.*** in the.nasal passage.,the.olfactory mucosa is dire.tly e.pose. to the.e.vironme.t to se.se.airborne.odorants;howe.e.,this also me.ns it can se.ve.as a dire.t route.of e.try from the.outside.world into the.*** a re.ult,olfactotropic infe.tions can have.se.ious conse.ue.ce.,including dysfunction of the.olfactory syste.,CNS invasion,disse.ination to the.lowe. re.piratory tract,and transmission be.we.n *** re.e.rch has shown that a distinctive.immune.re.ponse.is ne.de. to prote.t this ne.ronal and mucosal tissue.A be.te. unde.standing of innate.adaptive.and structural immune.barrie.s in the.olfactory mucosa is ne.de. to de.e.op e.fe.tive.the.ape.tics and vaccine. against olfactotropic microbe. such as ***,we.summarize.the.ramifications of SARS-CoV-2 infe.tion of the.olfactory mucosa,re.ie. the.subse.ue.t immune.re.ponse.and discuss important are.s of future.re.e.rch for olfactory immunity to infe.tious dise.se.

关键词： Mucosal immunology Ne.roimmunology Infe.tious Dise.se Sars-CoV-2

Supple.e.tation of vitamin e.or a botanical e.tract as antioxidants to improve.growth pe.formance.and he.lth of growing pigs house. unde. the.mone.tral or he.t-stre.se. conditions

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Journal of Animal Scie.ce.and Biote.hnology 2024年第3期15卷 1101-1118页

作者： Yse.ia V.Silva‑Guille. Consue.o Are.lano Je.fre. Wie.e.t R.De.n Boyd Gabrie.a e.Martine. e.ic van He.gte. De.artme.t of Animal Scie.ce North Carolina State UniversityRaleighNC 27695USA De.artme.t of Statistics North Carolina State UniversityRaleighNC 27695USA De.artme.t of Animal Scie.ce Texas A&M UniversityCollege StationTX 77843USA Animal Nutrition Re.e.rch LLCAlvatonKY 42122USA.

Background He.t stre.s has se.e.e.ne.ative.conse.ue.ce. on pe.formance.and he.lth of pigs,le.ding to significant e.onomic *** obje.tive.of this study was to inve.tigate.the.e.fe.ts of supple.e.tal vitamin e.and a botanical e.tract in fe.d or drinking wate. on growth pe.formance.inte.tinal he.lth,and oxidative.and immune.status in grow-ing pigs house. unde. he.t stre.s *** Duplicate.e.pe.ime.ts we.e.conducte.,e.ch using 64 crossbre. pigs with an initial body we.ght of 50.7±3.8 and 43.9±3.6 kg and age.of 13-we.k and 12-we.k,***(n=128)we.e.house. individually and assigne. within we.ght blocks and se. to a 2×4 factorial arrange.e.t consisting of 2 e.vironme.ts(the.mo-ne.tral(21.2℃)or he.t-stre.se.(30.9℃))and 4 supple.e.tation tre.tme.ts(control die.;control+100 IU/L of D-α-tocophe.ol in wate.;control+200 IU/kg of DL-α-tocophe.yl-ace.ate.in fe.d;or control+400 mg/kg of a botanical e.tract in fe.d).Re.ults He.t stre.s for 28 d re.uce.(P≤0.001)final body we.ght,ave.age.daily gain,and ave.age.daily fe.d intake.-7.4 kg,-26.7%,and-25.4%,re.pe.tive.y)but no e.fe.ts of supple.e.tation we.e.de.e.te.(P>0.05).Se.um vitamin e.incre.se.(Pamin e.supple.e.tation in wate. and in fe.d(1.64 vs.3.59 and 1.64 vs.3.24),but not for the.botanical e.tract(1.64 vs.1.67 mg/kg)and was gre.te. whe. supple.e.te. in wate. ***(P=0.002).Live. vitamin e.incre.se.(Pamin e.supple.e.tations in wate.(3.9 vs.31.8)and fe.d(3.9 vs.18.0),but not with the.botanical e.tract(3.9 vs.4.9 mg/kg).Se.um malondialde.yde.was re.uce. with he.t stre.s on d 2,but incre.se. on d 28(inte.action,Pe.te.(Pe.e.tation compare. to *** prolife.ation was re.uce.(P=0.037)in the.je.unum unde. he.t stre.s,but incre.se. in the.ile.m whe. vitamin e.was supple.e.te. in fe.d and wate. unde. he.t stre.s(inte.action,P=0.04).Tumor ne.rosis factor-αin je.unum and ile.m mucosa de.re.se. by he.t stre.s(Pe

关键词： Botanical e.tract Growing pigs He.t stre.s Immune.status Oxidative.status Tocophe.ol Wate.

Human de.tal pulp ste./stromal ce.ls in clinical practice

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World Journal of Ste. Ce.ls 2024年第2期16卷 54-57页

作者： Mohamme. e.Grawish De.artme.t of Oral Biology Faculty of DentistryMansoura UniversityMansoura 35561Egypt De.artme.t of Oral Biology Faculty of Oral and Dental MedicineDelta University for Science and TechnologyMansoura 11152Egypt

De.tal pulp ste./stromal ce.ls(DPSCs)are.fibroblast-like.ne.ral cre.t-de.ive.,and multipote.t ce.ls that can diffe.e.tiate.into se.e.al *** are.re.ative.y e.sy to isolate.from he.lthy and inflame. pulps,with little.e.hical conce.ns and can be.succe.sfully cryopre.e.ve. and *** the.ape.tic e.fe.ts of DPSCs de.ive. from animal or human source. have.be.n e.te.sive.y studie. through in-vitro and in-vivo animal e.pe.ime.ts and the.findings indicate. that DPSCs are.e.fe.tive.not only for de.tal dise.se. but also for syste.ic *** that translational re.e.rch is a critical ste. through which the.fundame.tal scie.tific discove.ie. could be.translate. into applicable.diagnostics and the.ape.tics that dire.tly be.e.it humans,se.e.al clinical studie. we.e.carrie. out to ge.e.ate.e.ide.ce.for the.e.ficacy and safe.y of autoge.ous or alloge.e.c human DPSCs(hDPSCs)as a tre.tme.t modality for use.in ce.l-base. the.apy,re.e.e.ative.me.icine.de.tistry and tissue.*** clinical me.icine.hDPSCs we.e.e.fe.tive.for tre.ting acute.ische.ic stroke.and human e.foliate. de.iduous te.th-conditione. me.ium(SHe.-CM)re.aire. vascular damage.of the.corpus cave.nous,which is the.main cause.of e.e.tile.*** in clinical de.tistry,autologous SHe. was able.to re.e.ne.ate.ne.rotic de.tal pulp afte. implantation into injure. te.th,and micrografts e.riche. with autologous hDPSCs and collage. sponge.we.e.conside.e. a tre.tme.t option for human intrabony *** contrast,hDPSCs did not add a significant re.e.e.ative.e.fe.t whe. the. we.e.use. for the.tre.tme.t of post-e.traction ***-scale.clinical studie. across dive.se.populations are.still lacking to provide.robust e.ide.ce.on the.safe.y and e.ficacy of hDPSCs as a ne. tre.tme.t option for various human dise.se. including de.tal-re.ate. proble.s.

关键词： De.tal pulp ste./stromal ce.ls Human clinical studie. Re.e.e.ative.me.icine Re.e.e.ative.de.tistry Ce.l-base. the.apy

Formadinium Cation Doping Stabilize. Ultra-de.p-blue.Le.d Halide.Pe.ovskite.Nanocrystal Light-e.itting Diode.

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Che.ical Re.e.rch in Chine.e.Unive.sitie. 2024年第3期40卷 556-560页

作者： Pui Ke. KO Jonathan e.HALPe.T De.artme.t of Che.istry The Hong Kong University of Science and TechnologyKowloonHong Kong 999077P.R.China

The.halide.migration e.fe.t in mixe.-halide.le.d-base. pe.ovskite.is a se.ious proble. hinde.ing the.de.e.opme.t of its display *** this study,we.have.succe.sfully addre.se. this issue.by re.orting formadinium(FA)dope. mixe.-halide.pe.ovskite.nanocrystals(NCs)with ultra-de.p-blue.e.ission of 450 nm,narrow bandwidth of 16 nm,and a high photolumine.ce.ce.quantum yie.d(PLQY)of 66%.The.pe.ovskite.nanocrystal light-e.itting diode.(NC-Le.s)using this nanocrystal as an active.laye. achie.e. a maximum e.te.nal quantum e.ficie.cy(e.e.of 0.32%,30-fold improve. compare. to that of pristine.and stable.e.e.trolumine.ce.ce.e.)spe.tra at 450 nm unde. a 4.9–8.0 V *** findings de.onstrate.the.pote.tial of our approach in de.e.oping stable.and e.ficie.t de.p blue.pe.ovskite.NC-Le.s.

关键词： Halide.pe.ovskite Light-e.itting diode De.p-blue